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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | The First Imported Case of Monkeypox in the Mainland of China—Chongqing Municipality,China,September 16,2022显示文摘Monkeypox is a zoonotic viral disease caused by the monkeypox virus(MPXV),and historically,all outbreaks have been linked to Africa;however,monkeypox has been posing an alarming challenge to the world in 2022(1)as approximately 60,000 cases have been reported in more than 100 nations and regions worldwide(2).Currently,many cases of monkeypox were identified in many nonendemic countries outside of Central and West Africa,and human-to-human transmission has occurred frequently,especially among men who have sex with men(MSM)presenting new clinical symptoms similar to syphilis and other sexually transmitted infections(3). | Hua Zhao Wenling Wang Li Zhao Sheng Ye Jingdong Song Roujian Lu Hua Zong Changcheng Wu Wei Huang Baoying Huang Yao Deng Ruhan A Wujuan Xie Li Qi Wenbo Xu Hua Ling Wenjie Tan | 2022 | China CDC weekly2022,4,38: | 35 |
| 3 | Polymorphism Analyses of Hepatitis B Virus X Gene in Hepatocellular Carcinoma Patients from Southern China显示文摘长期的肝炎 B 病毒( HBV )感染是主要原因 ofhepatocellular 癌( HCC )之一,并且 HBV X ( HBx )基因在HBV相关的 HCC.We 的分子的致病起一个关键作用调查了是否有特别 HBx 基因变化,从南部的中国在病人与 HCC 联系。HBx 基因被嵌套的聚合酶链反应(PCR ) 从 HBVcarrier 与 HCC 和 25 件浆液样品从病人在 51paraffin-embedded 肿瘤织物样品检验,搁浅单人赛的 conformational 多型性 andheteroduplex 分析。有从肿瘤织物样品的潜在地重要的变化的 HBx 基因被克隆,在肿瘤织物样品与出版 HBx 基因 sequence.HBV 遗传型定序并且排列被在肿瘤织物的31.3% HBx 基因碎片取样的基因多型性显示出的 HBx 的嵌套的 PCR.Analyses 分析有特殊 pattern.A 在 29 点突变伴随的 HBxgene 的 nt 382-400 的普通删除随机在四被检测有在 HBx 开的读物引起了框架移动的这个模式的选择肿瘤织物样品在 atnt 上与一条新站鳕鱼装裱 1818 ,导致 HBx 多肽链在这些情况中在 C 结束截断了。在四件随机选择的样品之中,三是 HBV 遗传型 B ,并且一个人没被我们的现在的 assay.Inanother 肿瘤织物样品检测,全身的 HBx 基因的扩大产出揭示的这碎片的 shorterfragment.Sequencing 在 1577 HBVgene.These 和 1840 结果建议的 nt 之间的 264 bp 删除那个 HBx 基因变化在 HCC 样品经常发生,并且在 HBx 基因的 nt 382-400 的删除可能在南部的中国在 HCC 的 carcinogenesis 起一个作用。 | Ping'an ZHU Deming TAN Zhongtian PENG Fei LIU Lin SONG | 2007 | Acta Biochimica et Biophysica Sinica2007,39,4: | 29 |
| 4 | Exploring atmospheric free-radical chemistry in China:the self-cleansing capacity and the formation of secondary air pollution显示文摘Since 1971,it has been known that the atmospheric free radicals play a pivotal role in maintaining the oxidizing power of the troposphere.The existence of the oxidizing power is an important feature of the troposphere to remove primary air pollutants emitted from human beings as well as those from the biosphere.Nevertheless,serious secondary air-pollution incidents can take place due to fast oxidation of the primary pollutants.Elucidating the atmospheric free-radical chemistry is a demanding task in the field of atmospheric chemistry worldwide,which includes two kinds of work:first,the setup of reliable radical detection systems;second,integrated field studies that enable closure studies on the sources and sinks of targeted radicals such as OH and NO3.In this review,we try to review the Chinese efforts to explore the atmospheric free-radical chemistry in such chemical complex environments and the possible link of this fast gas-phase oxidation with the fast formation of secondary air pollution in the city-cluster areas in China. | Keding Lu Song Guo Zhaofeng Tan Haichao Wang Dongjie Shang Yuhan Liu Xin Li Zhijun Wu Min Hu Yuanhang Zhang | 2019 | National Science Review2019,6,3: | 26 |
| 5 | Clinical evaluations of mineralized collagen in the extraction sites preservation显示文摘The purpose of this study was to explore the different effects between biomimetic mineralized collagen(MC)and ordinary physically blended hydroxyapatite/collagen(HA/Col)composite in evaluating new bone formation and regenerated bone height in human extraction sockets.Thirty-four patients who cannot retain teeth caused by trauma or decay were randomly selected from Department of Stomatology of Dongzhimen Hospital from December 2013 to December 2014.The patients were randomly divided into two groups.After the operation of tooth extraction,17 patients were implanted with biomimetic MC(MC group),and other 17 patients were implanted with ordinary physically blended nHA/Col composite(nHA/Col group).X-ray positioning projection by auto-photographing was taken to test the distance between the lowest position and the neighboring CEJm-CEJd immediately,1 month and 3 months after the operation.The height of new bone formation of the MC group was significantly higher than the nHA/Col group.Biomimetic MC showed better clinical outcomes in the bone formation for extraction site preservation and would have broad application prospect in the field of oral and maxillofacial surgeries. | Lu Feng Liang Zhang Yun Cui Tian-Xi Song Zhi-Ye Qiu Xiu-Mei Wang Bao-Sheng Tan | 2016 | Regenerative Biomaterials2016,3,1: | 26 |
| 6 | Surveillance, epidemiology, and pathogen spectrum of hand, foot, and mouth disease in mainland of China from 2008 to 2017显示文摘Hand,foot and mouth disease(HFMD)was reported in May 2,2008 to be the 38th legally notifiable disease in China's National Notifiable Disease Reporting and Surveillance System.In order to solve the infection,an extensive three-level HFMD surveillance laboratory network was established.In this study,the framework of that network is assessed and the incidence of HFMD in China from 2008 to 2017 is reported using a descriptive epidemiologic method.During these 10 years,a series of techniques have been widely applied in all the network laboratories.Using information and material obtained from the network,a virus bank and database containing 18,238 viruses were established.Nationally,18,184,834 HFMD cases,including 152,436 severe cases and 3633 fatal cases,were reported in mainland of China.The average annual incidence in the population was 133.99/100,000 people,with a maximum incidence of 205.06/100,000 people in 2014.The incidence and mortality rates of HFMD were the highest in children aged 1–2 years.The numbers of reported cases fluctuated,with a high incidence observed every 2 years.An overall increase in the number of reported cases was also observed throughout the study period.Despite this,the incidence of severe cases and the mortality rate have been decreasing.High-risk regions are located in southern,eastern,and central China.Two peaks of HFMD infection cases were observed annually except for Northeast China.Different proportions of enterovirus serotypes were observed during the studied years.The predominant enterovirus varies from year to year,but the disease severity is always closely related to the specific serotype.EV-A71 is the dominant serotype associated with severe and fatal cases,with constituent ratios of 70.03%and 92.23%,respectively.The studied highly sensitive and efficient surveillance network provides information that is critical for prevention and control of the disease.It is extremely necessary and important to continuously conduct extensive virological surveillance for HFMD. | Tianjiao Ji Taoli Han Xiaojuan Tan Shuangli Zhu Dongmei Yan Qian Yang Yang Song Aili Cui Yan Zhang Naiying Mao Songtao Xu Zhen Zhu Dandan Niu Yong Zhang Wenbo Xu | 2019 | Biosafety and Health2019,1,1: | 26 |
| 7 | Deep Learning and Its Applications in Biomedicine显示文摘Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data,such as medical images,electroencephalography,genomic and protein sequences.Learning from these data facilitates the understanding of human health and disease.Developed from arti?cial neural networks,deep learning-based algorithms show great promise in extracting features and learning patterns from complex data.The aim of this paper is to provide an overview of deep learning techniques and some of the state-of-the-art applications in the biomedical?eld.We?rst introduce the development of arti?cial neural network and deep learning.We then describe two main components of deep learning,i.e.,deep learning architectures and model optimization.Subsequently,some examples are demonstrated for deep learningapplications,including medical image classi?cation,genomic sequence analysis,as well as protein structure classi?cation and prediction.Finally,we offer our perspectives for the future directions in the?eld of deep learning. | Chensi Cao Feng Liu Hai Tan Deshou Song Wenjie Shu Weizhong Li Yiming Zhou Xiaochen Bo Zhi Xie | 2018 | Genomics, Proteomics & Bioinformatics2018,16,1: | 22 |
| 8 | Age-related rhesus macaque models of COVID-19显示文摘Background:Since December 2019,an outbreak of the Corona Virus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus(SARS-CoV-2)in Wuhan,China,has become a public health emergency of international concern.The high fatality of aged cases caused by SARS-CoV-2 was a need to explore the possible age-related phenomena with non-human primate models.Methods:Three 3-5 years old and two 15 years old rhesus macaques were intratracheally infected with SARS-CoV-2,and then analyzed by clinical signs,viral replication,chest X-ray,histopathological changes and immune response.Results:Viral replication of nasopharyngeal swabs,anal swabs and lung in old monkeys was more active than that in young monkeys for 14 days after SARS-CoV-2 challenge.Monkeys developed typical interstitial pneumonia characterized by thickened alveolar septum accompanied with inflammation and edema,notably,old monkeys exhibited diffuse severe interstitial pneumonia.Viral antigens were detected mainly in alveolar epithelial cells and macrophages.Conclusion:SARS-CoV-2 caused more severe interstitial pneumonia in old monkeys than that in young monkeys.Rhesus macaque models infected with SARS-CoV-2 provided insight into the pathogenic mechanism and facilitated the development of vaccines and therapeutics against SARS-CoV-2 infection. | Pin Yu Feifei Qi Yanfeng Xu Fengdi Li Peipei Liu Jiayi Liu Linlin Bao Wei Deng Hong Gao Zhiguang Xiang Chong Xiao Qi Lv Shuran Gong Jiangning Liu Zhiqi Song Yajin Qu Jing Xue Qiang Wei Mingya Liu Guanpeng Wang Shunyi Wang Haisheng Yu Xing Liu Baoying Huang Wenling Wang Li Zhao Huijuan Wang Fei Ye Weimin Zhou Wei Zhen Jun Han Guizhen Wu Qi Jin Jianwei Wang Wenjie Tan Chuan Qin | 2020 | Animal Models and Experimental Medicine2020,3,1: | 22 |
| 9 | Long-term results of endovascular therapy for proximal subclavian arterial obstructive lesions显示文摘背景 Endovascular 治疗是为锁骨下的动脉的局部性的吸藏的一种处理选择。在与 59 个病人一起的长期的经验是在1998年6月和2008年9月之间的 presented.Methods 的这份报告,我们使用了 endovascular 治疗在 59 个病人对待 61 锁骨下的动脉的妨碍的损害( 46 男性和 13 女性,有一个平均数的 34-82 岁变老( 61.9 眠瑩?佃?????????????? | WANG Ke-qin WANG Zhong-gao YANG Bao-zhong YUAN Chao ZHANG Wang-de YUAN Biao XING Tong SONG Sheng-han LI Tan LIAO Chuan-jun ZHANG Yang | 2010 | Chinese Medical Journal2010,,1: | 21 |
| 10 | USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors显示文摘(K63 ) 离氨酸 63 连接了 RIG-I 戏的 ubiquitination 在类型的激活的一个关键角色我干扰素小径,然而,为它的 deubiquitination 负责的分子的机制仍然糟糕被理解。这里,我们报导 deubiquitination 酶 ubiquitin 特定的朊酶(USP3 ) 3 否定地调整类型的激活我干扰素由指向 RIG-I 发信号。USP3 击倒 RIG-I 的明确地提高的连接 K63 的 ubiquitination, upregulated IRF3 的 phosphorylation 并且扩充了类型的生产我干扰素 cytokines 和抗病毒的免疫。我们进一步证明在 unstimulated 或 uninfected 房间在 USP3 和 RIG-I-like 受体( RLR )之间没有相互作用,但是在病毒的感染或 ligand 刺激之上, USP3 绑在 RLR 的 caspase 激活招募领域然后通过它的锌手指的合作劈开 polyubiquitin 链Ub有约束力的领域和 USP 催化领域。变化分析表明到 RIG-I 上的 polyubiquitin 链的 USP3 的那绑定是为它 polyubiquitin 链的劈开的前提步。我们的调查结果在 RIG-I 激活识别 USP3 的一个以前未被认出的角色并且提供卓见进 USP3 由禁止 RIG-I 发信号和抗病毒的免疫的机制。 | Jun Cui Yanxia Song Yinyin Li Qingyuan Zhu Peng Tan Yunfei Qin Helen Y Wang Rong-Fu Wang | 2014 | Cell Research2014,24,4: | 20 |
| 11 | Sperm DNA damage has a negative effect on early embryonic development following in vitro fertilization显示文摘精子 DNA 损坏作为男不孕的重要 biomarker 被认出。调查这,精子 DNA 损坏被精液的测试和能动精子由联合密度坡度 centrifugation (DGC ) 收获了的精子染色质分散(SCD ) 估计,在 161 的游泳起来联合在 vitro 授精(IVF ) 经历。精液分析和精子 DNA 损坏结果在确实完成了怀孕的夫妇之间被比较。精子 DNA 损坏水平在二个组之间是显著地不同的(P < 0.05 ) 并且否定地与 IVF 结果被相关。逻辑回归分析证实它是为完成临床的怀孕的一个独立预言者。IVF 结果上的精子 DNA 损坏的不同层次的效果也被比较。在白天 3 胚胎质量,胚囊形成率,和培植和怀孕率有重要差别(P < 0.05 ) ,然而并非处于在二个组之间的基本授精率。因此,由 SCD 测量了的精子 DNA 损坏为预言临床的怀孕率追随者 IVF 显得有用。 | Wei-Wei Zheng Ge Song Qi-Ling Wang Shan-Wen Liu Xiao-Li Zhu Shun-Mei Deng An Zhong Yu-Mei Tan Ying Tan | 2018 | Asian Journal of Andrology2018,20,1: | 19 |
| 12 | Experimental study on dynamic mechanical property of cemented tailings backfill under SHPB impact loading显示文摘Cemented tailings backfill(CTB) have increasingly been used in recent years to improve the stability of mining stopes in deep underground mines. Deep mining processes are often associated with rock bursting and high-speed dynamic loading conditions. Therefore, it is important to investigate the characteristics and dynamic mechanical behavior of CTB. This paper presents the results of dynamic tests on CTB specimens with different cement and solid contents using a split Hopkinson pressure bar(SHPB). The results showed that some CTB specimens exhibited one to two lower stress peaks after reaching dynamic peak stress before they completely failed. The greater the cement-to-tailings ratio is, the more obvious the strain reaction. This property mainly manifested as follows. First,the dynamic peak stress increased with the increase of the cement-to-tailings ratio when the impact velocity was fixed. Second, the dynamic peak stress had a quadratic relationship with the average stress rate. Third, the cement-to-tailings ratio could enhance the increase rate of dynamic peak stress with strain rate. In addition, the dynamic strength enhancement factor K increased with the increase of strain rate, and its value was larger than that of the rock samples. The failure modes of CTB specimens under low-speed impact were tensile failure and X conjugate shear failure, where were nearly the same as those under static uniaxial and triaxial compression. The CTB specimens were crushed and broken under critical strain, a failure mode similar to that of low-strength concrete. The results of the experimental research can improve the understanding of the dynamic mechanical properties of CTB and guide the strength design of deep mining backfills. | Yu-ye Tan Xin Yu Davide Elmo Lin-hui Xu Wei-dong Song | 2019 | International Journal of Minerals,Metallurgy and Materials2019,26,4: | 19 |
| 13 | IPO initial returns in China: Underpricing or overvaluation?显示文摘This paper separates the amount of IPO underpricing(primary market underpricing) and overvaluation(secondary market overvaluation) from the value of an IPO's initial return to evaluate the relative importance of these two factors and their main determinants. Using data on the IPOs of 948 Chinese firms, we find that average initial returns are 66% and that underpricing and overvaluation are between 14–22% and 44–53%, respectively, depending on the method used to assess firms' intrinsic values. In addition, while both the value of the initial return and the extent of overvaluation are significantly negatively related to post-IPO long-run stock performance, overvaluation can predict post-IPO performance better than the value of the initial return. Value uncertainty in IPOs is positively related to both underpricing and overvaluation, and both the underwriter's reputation and the existence of pricing regulation are positively related to underpricing. Investor sentiment has a positive effect on overvaluation but has no effect or a negative effect on underpricing. Overall, our results suggest that in China overvaluation accounts for a larger proportion of the initial return than underpricing,and that underpricing and overvaluation have different determinants. | Shunlin Song JinSong Tan Yang Yi | 2014 | China Journal of Accounting Research2014,,1: | 19 |
| 14 | Microarray-Assisted Fine-Mapping of Quantitative Trait Loci for Cold Tolerance in Rice显示文摘包括冷压力抵抗,许多重要农学的特点由量的特点 loci (QTL ) 复杂、控制。这些 QTL 的隔离将极大地有益于农业工业,但是它是一项挑战性的任务。这研究由把 microarray 与印射 QTL 相结合以便在早幼苗的舞台从寒冷容忍的变化 IL112 识别寒冷容忍的 QTL 探索了综合策略。IL112 的所有早幼苗在 45 点为 9 d 通常幸存吗?? | Fengxia Liu Wenying Xu Qian Song Lubin Tan Jiayong Liu Zuofeng zhu Yongcai Fu Zhen Su Chuanqing Sun | 2013 | Molecular Plant2013,6,3: | 17 |
| 15 | Follow-up study of hepatitis C virus infection in uremic patients on maintenance hemodialysis for 30 months显示文摘INTRODUCTIONA high prevalence of antibodies to hepatitis C virus(HCV)(range from 3.3%-80%)has beenreported in hemodialysis(HD)patients,andworrisome as it often becomes chronic and induceschronic liver disease,therefore thenephrologists face a major challenge of how toprevent it.The main route of HCV transmission | Nian Song Wang Lu Tan Liao Yan Juan Zhu Wei Pan Fang Fang | 2000 | World Journal of Gastroenterology2000,6,6: | 17 |
| 16 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021,3,21: | 16 |
| 17 | Stability of QTL Across Environments and QTL-by-Environment Interactions for Plant and Ear Height in Maize显示文摘Better understanding of genotype-by-environment interaction(GEI)is expected to provide a solid foundation for genetic improvement of crop productivity especially under drought-prone environments.To elucidate the genetic basis of the plant and ear height,2 F2:3 populations were derived from the crosses of Qi 319 × Huangzaosi(Q/H)and Ye 478 × Huangzaosi(Y/H)with 230 and 235 families,respectively,and their parents were evaluated under 3 diverse environments in Henan,Beijing,and Xinjiang,China during the year of 2007 and 2008,and all the lines were also evaluated under water stress environment.The mapping results showed that a total of 21 and 12 QTLs were identified for plant height in the Q/H and Y/H population,respectively,and 24 and 13 QTLs for ear height,respectively.About 56 and 73% of the QTLs for 2 traits did not present significant QTL-by-environment interaction(QEI)in the normal joint analyses for Q/H and Y/H population,respectively,and about 73% of the QTLs detected did not show significant QEI according to joint analyses for stress condition in Q/H.Most of the detected major QTLs exhibited high stability across different environments.Besides,several major QTLs were detected with large and consistent effect under normal condition(Chr.6 and 7 in Q/H;Chr.1,3 and 9 in Y/H),or across 2 water regimes(Chr.1,8 and 10 for in Q/H).There were several constitutive QTLs(3 for Q/H and 1 for Y/H)with no or minor QTL-by-environment for the 2 populations.Finally,we found several genomic regions(Chr.1,10,etc.)to be co-located across the populations,which could provide useful reference for genetic improvement of these traits in maize breeding programs.Comparative genomic analysis revealed that 3 genes/genetic segments associated with plant height in rice were orthologous to these 3 identified genomic regions carrying the major QTLs for plant and ear height on Chr.1,6,and 8,respectively. | ZHANG Yan LI Yong-xiang WANG Wang LIU Zhi-zhai LIU Cheng PENG Bo TAN Wei-wei WANG Di SHI Yun-su SUN Bao-cheng SONG Yan-chun WANG Tian-yu LI Yu | 2010 | Agricultural Sciences in China2010,9,10: | 16 |
| 18 | Influence of mesoscale eddies on primary production in the South China Sea during spring inter-monsoon period显示文摘Mesoscale eddies have been suggested to have an impact on biological carbon fixation in the South China Sea(SCS). However, their overall contribution to primary production during the spring inter-monsoon period is still unknown. Based on large-scale biological and environmental in situ observations and synchronous remote sensing data, the distribution patterns of phytoplankton biomass and the primary production, and the role of mesoscale eddies in regulating primary production in different eddy-controlled waters were investigated. The results suggested that the surface chlorophyll a concentrations and water column integrated primary production(IPP) are significantly higher in cyclonic eddies and lower in the anticyclonic eddies as compared to that in non-eddy waters. Although eddies could affect various environmental factors, such as nutrients, temperature and light availability, nutrient supply is suggested to be the most important one through which mesoscale eddies regulated the distribution patterns of phytoplankton biomass and primary production. The estimated IPP in cyclonic and anticyclonic eddies are about 29.5% higher and 16.6% lower than the total average in the whole study area, respectively, indicating that the promotion effect of mesoscale cold eddies on the primary production was much stronger than the inhibition effect of the warm eddies per unit area. Overall, mesoscale eddies are crucial physical processes that affect the biological carbon fixation and the distribution pattern of primary production in the SCS open sea, especially during the spring inter-monsoon period. | HU Zifeng TAN Yehui SONG Xingyu ZHOU Linbin LIAN Xiping HUANG Liangmin HE Yinghui | 2014 | Acta Oceanologica Sinica2014,33,3: | 16 |
| 19 | The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize显示文摘Maize is a globally important crop that was a classic model plant for genetic studies. Here, we report a 2.2 Gb draft genome sequence of an elite maize line, HuangZaoSi (HZS). Hybrids bred from HZS-improved lines (HILs) are planted in more than 60% of maize fields in China. Proteome clustering of six completed sequeneed maize genomes show that 638 proteins fall into 264 HZS-specific gene families with the majority of contributions from tandem duplication events. Resequencing and comparative analysis of 40 HZSrelated lines reveals the breeding history of HILs. More than 60% of identified selective sweeps were clustered in identity.by.descent conserved regions, and yield-related genes/QTLs were enriched in HZS characteristic selected regions. Furthermore, we dem on strated that HZS-specific family genes were not uniformly distributed in the genome but enriched in improvement/function.related genomic regions. This study provides an important and novel resource for maize genome research and expands our knowledge on the breadth of genomic variation and improvement history of maize. | Chunhui Li Wei Song Yingfeng Luo Shenghan Gao Ruyang Zhang Zi Shi Xiaqing Wang Ronghuan Wang Fengge Wang Jidong Wang Yanxin Zhao Aiguo Su Shuai Wang Xin Li Meijie Luo Shuaishuai Wang Yunxia Zhang Jianrong Ge Xinyu Tan Ye Yuan Xiaochun Bi Hang He Jianbing Yan Yuandong Wang Songnian Hu Jiuran Zhao | 2019 | Molecular Plant2019,12,3: | 15 |
| 20 | Bioptical microcycles of laminated speleothems from China and their chronological significance显示文摘Interfaces of microlayers, in most stalagmites from China, consist of opaque and organic materials. Observed with microscope, the interfaces seem dark under transmitted light and luminiferous under reflected fluorescent light. Stalagmites in which the two optical characters are unified spatially would be most suitable for cross-dating use, and can play an important role in the study on speleochronology and speleoclimatology. | Ming Tan Xiaoguang Qin Linmei Shen Xianfeng Wang Yongjin Wang Tieying Li Linhua Song Laihong Wang Dongsheng Liu | 1999 | Chinese Science Bulletin1999,44,17: | 14 |