|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer显示文摘AIM:To study how lymph node metastasis(LNM) risk is stratified in undifferentiated-type early gastric cancer(undiff-EGC) dependent on combinations of risk factors.METHODS:Five hundred and sixty-seven cases with undiff-EGC undergoing gastrectomy with lymphadenectomy were examined retrospectively.Using clinicopathological factors of patient age,location,size,an endoscopic macroscopic tumor form,ulceration,depth,histology,lymphatic involvement(LI) and venous involvement(VI),LNM risk was examined and stratified by conventional statistical analysis and datamining analysis.RESULTS:LNM was positive in 44 of 567 cases(7.8%).Univariate analysis revealed > 2 cm,protrusion,submucosal(sm),mixed type,LI and VI as significant prognostic factors and > 2 cm and LI-positive were independent factors by multivariate analysis.In preoperatively evaluable factors excluding LVI,sm and > 2 cm were independent factors.According to the depth and size,cases were categorized into the low-risk group [m and ≤ 2 cm,0%(LNM incidence)],the moderaterisk group(m and > 2 cm,5.6%; and sm and ≤ 2 cm,6.0%),and the high-risk group(sm and > 2 cm,19.3%).On the other hand,LNM occurred in 1.4% in all LI-negative cases,greatly lower than 28.2% in all LI-positive cases,and LNM incidence was low in LInegative cases even in the moderate- and high-risk groups.CONCLUSION:LNM-related factors in undiff-EGC were depth and size preoperatively while those were LI and size postoperatively.Among these factors,LI was the most significantly correlated factor. | Yukiko Asakawa Masahiko Ohtaka Shinya Maekawa Mitsuharu Fukasawa Yasuhiro Nakayama Tatsuya Yamaguchi Taisuke Inoue Tomoyoshi Uetake Minoru Sakamoto Tadashi Sato Yoshihiko Kawaguchi Hideki Fujii Kunio Mochizuki Masao Hada Toshio Oyama Tomotaka Yasumura Kosaku Omata Atsushi Nishiyama Keiichi Naito Hideo Hata Yoshiaki Haba Kazuyuki Miyata Haruhisa Saitoh Yoichi Yamadera Kazuo Miura Akira Kawaoi Tohru Abe Hajime Tsunoda Yuji Honda Masayuki Kurosaki Nobuyuki Enomoto | 2015 | World Journal of Gastroenterology2015，21，9： | 8 |
| 2 | Clinicopathological and prognostic significance of microRNA-107 andits relationship to DICER1 mRNA expression in gastric cancer显示文摘 | Taisuke Inoue Hisae Iinuma Etsushi Ogawa Tsuyoshi Inaba Ryoji Fukushima | 2012 | Oncology Reports2012，，6： | 2 |
| 3 | Differential Diagnosis of Hepatic Tumors: Value of Contrast-Enhanced Harmonic Sonography Using the Newly Developed Contrast Agent, Sonazoid显示文摘 | Hatanaka Kinuyo Kudo Masatoshi Minami Yasunori Ueda Taisuke Tatsumi Chie Kitai Satoshi Takahashi Shunsuke Inoue Tatsuo Hagiwara Satoru Chung Hobyung Ueshima Kazuomi Maekawa Kiyoshi | 2008 | Intervirology2008，，： | 1 |
| 4 | Analysis of viral amino acids sequences and the IL28B SNP influencing the development of hepatocellular carcinoma in chronic hepatitis C显示文摘 | Mika Miura Shinya Maekawa Makoto Kadokura Ryota Sueki Kazuki Komase Hiroko Shindo Takako Ohmori Asuka Kanayama Kuniaki Shindo Fumitake Amemiya Yasuhiro Nakayama Takatoshi Kitamura Tomoyoshi Uetake Taisuke Inoue Minoru Sakamoto Shunichi Okada Nobuyuki Enom | 2012 | Hepatology International2012，，1： | 1 |
| 5 | Assessment of Gd-EOB-DTPA-enhanced MRI for HCC and dysplastic nodules and comparison of detection sensitivity versus MDCT显示文摘 | Tatsuo Inoue Masatoshi Kudo Mina Komuta Sosuke Hayaishi Taisuke Ueda Masahiro Takita Satoshi Kitai Kinuyo Hatanaka Norihisa Yada Satoru Hagiwara Hobyung Chung Toshiharu Sakurai Kazuomi Ueshima Michiie Sakamoto Osamu Maenishi Tomoko Hyodo Masahiro Okada Se | 2012 | Journal of Gastroenterology2012，，9： | 1 |
| 6 | Analysis of viral amino acids sequences and the IL28B SNP influencing the development of hepatocellular carcinoma in chronic hepatitis C显示文摘 | Mika Miura Shinya Maekawa Makoto Kadokura Ryota Sueki Kazuki Komase Hiroko Shindo Takako Ohmori Asuka Kanayama Kuniaki Shindo Fumitake Amemiya Yasuhiro Nakayama Takatoshi Kitamura Tomoyoshi Uetake Taisuke Inoue Minoru Sakamoto Shunichi Okada Nobuyuki Enom | 2012 | Hepatology International2012，，1： | 1 |
| 7 | Elevation of serum matrix metalloproteinase-3 as a predictive marker for the long-term disability of rheumatoid arthritis patients in a prospective observational cohort IORRA显示文摘 | Mikiko Shinozaki Eisuke Inoue Ayako Nakajima Masako Hara Taisuke Tomatsu Naoyuki Kamatani Hisashi Yamanaka | | 0，，： | 1 |
| 8 | Deep-Sequencing Analysis of the Association between the Quasispecies Nature of the Hepatitis C Virus Core Region and Disease Progression显示文摘 | Mika Miura Shinya Maekawa Shinichi Takano Nobutoshi Komatsu Akihisa Tatsumi Yukiko Asakawa Kuniaki Shindo Fumitake Amemiya Yasuhiro Nakayama Taisuke Inoue Minoru Sakamoto Atsuya Yamashita Kohji Moriishi Nobuyuki Enomoto | 2013 | Journal of Virology2013，，23： | 1 |
| 9 | Clinical effects of adalimumab treatment with concomitant azathioprine in Japanese Crohn's disease patients显示文摘AIM:To assess adalimumab's efficacy with concomitant azathioprine (AZA) for induction and maintenance of clinical remission in Japanese Crohn's disease (CD) patients. METHODS:This retrospective, observational, singlecenter study enrolled 28 consecutive CD patients treated with adalimumab (ADA). Mean age and mean disease duration were 38.1 ± 11.8 years and 11.8 ± 10.1 years, respectively. The baseline mean Crohn's disease activity index (CDAI) and C-reactive protein were 177.8 ± 82.0 and 0.70 ± 0.83 mg/dL, respectively. Twelve of these patients also received a concomitant stable dose of AZA. ADA was subcutaneously administered:160 mg at week 0, 80 mg at week 2, followed by 40 mg every other week. Clinical response and remission rates were assessed via CDAI and C-reactive protein for 24 wk. RESULTS:The mean CDAI at weeks 2, 4, 8, and 24 was 124.4, 120.2, 123.6, and 135.1, respectively. The CDAI was significantly decreased at weeks 2 and 4 with ADA and was significantly suppressed at 24 wk with ADA/AZA. Overall clinical remission rates at weeks 4 and 24 were 66.7% and 63.2%, respectively. Although no statistically significant difference in C-reactive protein was demonstrated, ADA with AZA resulted in a greater statistically significant improvement in CDAI at 24 wk, compared to ADA alone. CONCLUSION:Scheduled ADA with concomitant AZA may be more effective for clinical remission achievement at 24 wk in Japanese Crohn's disease patients. | Kumi Ishida Takuya Inoue Kaori Fujiwara Taisuke Sakanaka Ken Narabayashi Sadaharu Nouda Toshihiko Okada Kazuki Kakimoto Takanori Kuramoto Ken Kawakami Yosuke Abe Toshihisa Takeuchi Mitsuyuki Murano Satoshi Tokioka Eiji Umegaki Kazuhide Higuchi | 2013 | World Journal of Gastroenterology2013，19，17： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员