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| 1 | Deep-learning classifier with ultrawide-field fundus ophthalmoscopy for detecting branch retinal vein occlusion显示文摘AIM: To investigate and compare the efficacy of two machine-learning technologies with deep-learning(DL) and support vector machine(SVM) for the detection of branch retinal vein occlusion(BRVO) using ultrawide-field fundus images. METHODS: This study included 237 images from 236 patients with BRVO with a mean±standard deviation of age 66.3±10.6 y and 229 images from 176 non-BRVO healthy subjects with a mean age of 64.9±9.4 y. Training was conducted using a deep convolutional neural network using ultrawide-field fundus images to construct the DL model. The sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and area under the curve(AUC) were calculated to compare the diagnostic abilities of the DL and SVM models. RESULTS: For the DL model, the sensitivity, specificity, PPV, NPV and AUC for diagnosing BRVO was 94.0%(95%CI: 93.8%-98.8%), 97.0%(95%CI: 89.7%-96.4%), 96.5%(95%CI: 94.3%-98.7%), 93.2%(95%CI: 90.5%-96.0%) and 0.976(95%CI: 0.960-0.993), respectively. In contrast, for the SVM model, these values were 80.5%(95%CI: 77.8%-87.9%), 84.3%(95%CI: 75.8%-86.1%), 83.5%(95%CI: 78.4%-88.6%), 75.2%(95%CI: 72.1%-78.3%) and 0.857(95%CI: 0.811-0.903), respectively. The DL model outperformed the SVM model in all the aforementioned parameters(P<0.001). CONCLUSION: These results indicate that the combination of the DL model and ultrawide-field fundus ophthalmoscopy may distinguish between healthy and BRVO eyes with a high level of accuracy. The proposed combination may be used for automatically diagnosing BRVO in patients residing in remote areas lacking access to an ophthalmic medical center. | Daisuke Nagasato Hitoshi Tabuchi Hideharu Ohsugi Hiroki Masumoto Hiroki Enno Naofumi Ishitobi Tomoaki Sonobe Masahiro Kameoka Masanori Niki Yoshinori Mitamura | 2019 | International Journal of Ophthalmology(English edition)2019，12，1： | 16 |
| 2 | Hypertriglyceridemia is positively correlated with the development of colorectal tubular adenoma in Japanese men显示文摘瞄准:决定在浆液类脂化合物层次和结肠的息肉形成之间的真实协会。方法:我们执行了大规模分析在表面的腺瘤或癌和禁食浆液在为为结肠癌屏蔽经历了全部的结肠镜检查的病人全部的胆固醇(TC ) 和 triglycerides (TG ) 铺平的肤色的发生之间的关联的回顾的学习。结果:没有任何肿瘤的损害,两水平显著地作为与病人相比与腺瘤在病人被提高(TC 207.6+/-29.5 对 199.5+/-34.3, n=4883, P<0.001;TG 135.0+/-82.2 对 108.7+/-71.5, n=4874, P<0.001 ) 。差别在有管状腺瘤然而并非在那些与的病人是重要的覆有一层绒毛或 serrated 腺瘤。包括年龄和性别的多重逻辑回归分析表明 TG 是在男性(P<0.01 ) ,然而并非在女病人的一个独立关联因素。在有侵略的癌的病人的 TG 的水平没与腺瘤在病人从那显示出重要举起。这些调查结果建议 hypertriglyceridemia 是为在人的结肠的腺瘤的一个独立风险因素。结论:尽管浆液甘油三酸酯的高水平不看起来机械地涉及癌的发展,有全部的结肠镜检查的浆液 TG 和集中的监视的减小可以与 hypertriglyceridemia 在人有利益。 | Masafumi Tabuchi Joji Kitayama Hirokazu Nagawa | 2006 | World Journal of Gastroenterology2006，12，8： | 11 |
| 3 | Transient receptor potential vanilloid 4-dependent calcium influx and ATP release in mouse and rat gastric epithelia显示文摘AIM: To explore the expression of transient receptor potential vanilloid 4(TRPV4) and its physiological meaning in mouse and rat gastric epithelia. METHODS: RT-PCR and immunochemistry were used to detect TRPV4 m RNA and protein expression in mouse stomach and a rat normal gastric epithelial cell line(RGE1-01), while Ca2+-imaging and electrophysiology were used to evaluate TRPV4 channel activity. ATP release was measured by a luciferin-luciferase assay. Gastric emptying was also compared between WT and TRPV4 knockout mice. RESULTS: TRPV4 m RNA and protein were detected in mouse tissues and RGE1-01 cells. A TRPV4-specific agonist(GSK1016790A) increased intracellular Ca2+ concentrations and/or evoked TRPV4-like current activities in WT mouse gastric epithelial cells andRGE1-01 cells, but not TRPV4 KO cells. GSK1016790 A or mechanical stimuli induced ATP release from RGE1-01 cells while TRPV4 knockout mice displayed delayed gastric emptying in vivo. CONCLUSION: TRPV4 is expressed in mouse and rat gastric epithelium and contributes to ATP release and gastric emptying. | Hiroshi Mihara Nobuhiro Suzuki Ammar Abdullkader Boudaka Jibran Sualeh Muhammad Makoto Tominaga Yoshiaki Tabuchi Toshiro Sugiyama | 2016 | World Journal of Gastroenterology2016，22，24： | 5 |
| 4 | Low-dose rectal diclofenac for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a randomized controlled trial显示文摘 | Taiga Otsuka Seiji Kawazoe Shunya Nakashita Saori Kamachi Satoshi Oeda Chinatsu Sumida Takumi Akiyama Keisuke Ario Masaru Fujimoto Masanobu Tabuchi Takahiro Noda | 2012 | Journal of Gastroenterology2012，，8： | 4 |
| 5 | Expression of microRNA-208 is Associated With Adverse Clinical Outcomes in Human Dilated Cardiomyopathy显示文摘 | Mamoru Satoh Yoshitaka Minami Yuji Takahashi Tsuyoshi Tabuchi Motoyuki Nakamura | 2010 | Journal of Cardiac Failure2010，，5： | 2 |
| 6 | Changes in choroidal thickness in healthy pediatric individuals: a longitudinal study显示文摘● AIM: To investigate the changes in the choroidal thickness in healthy pediatric children in a longitudinal study, and to determine the ocular and systemic parameters that were significantly correlated with the changes in the choroidal thickness.● METHODS: This study included 64 eyes of 34 healthy Japanese children with a mean age(±SD) of 4.4(±0.4)y(range, 3.6-5.8 y) at baseline. Swept-source optical coherence tomography(SS-OCT) was used to record images of the retina and choroid at the baseline and after a mean followup period of about 1.5 y. The 3 D raster scan protocol was used to construct the choroidal thickness map. Mean choroidal thickness was calculated for each of the nine sectors of the Early Treatment Diabetic Retinopathy Study grid. Best-corrected visual acuity, axial length, body height, and weight were also measured. Changes in measurements were defined as the baseline values subtracted from the values at the final visit. A generalized estimating equation was used to eliminate the effect of within-subject intereye correlations.● RESULTS: The mean central choroidal thickness was significantly reduced during the follow-up period(baseline, 301.8±8.6 μm; final visit, 286.6±8.0 μm, P<0.001). The decrease in the choroidal thickness was greatest in the central sector, followed by the sectors of the inner and outer rings. The inner and outer rings had diameters of 1 to 3 mm and 3 to 6 mm, respectively. The changes in the choroidal thickness in the central, inner ring, and outer ring sectors were significantly and negatively correlated with the age, baseline body height, baseline body weight, and elongation of the axial length.● CONCLUSION: These results indicate that the choroidal thickness among preschool-aged Japanese children decreased significantly during the follow-up period. The choroidal thinning is significantly associated with the elongation of axial length. These characteristics should be considered in the evaluation of choroidal thickness in younger children with retinochoroidal disorders. | Eiko Ohsugi Yoshinori Mitamura Kayo Shinomiya Masanori Niki Hiroki Sano Toshihiko Nagasawa Yukiko Shimizu Daisuke Nagasato Hitoshi Tabuchi | 2018 | International Journal of Ophthalmology(English edition)2018，11，7： | 2 |
| 7 | Optimum Treatment Strategy for Superficial Esophageal Cancer: Endoscopic Mucosal Resection versus Radical Esophagectomy显示文摘 | Hiromasa Fujita Susumu Sueyoshi Hideaki Yamana Koji Shinozaki Uhi Toh Yuichi Tanaka Takashi Mine Masahiro Kubota Kazuo Shirouzu Atsushi Toyonaga Hiroshi Harada Sigeki Ban Masahide Watanabe Yukihiko Toda Emi Tabuchi Naofumi Hayabuchi Hiroki Inutsuka | 2001 | World Journal of Surgery2001，，4： | 2 |
| 8 | Cervical spondylosis: Evaluation of microstructural changes in spinal cord white matter and gray matter by diffusional kurtosis imaging显示文摘 | Masaaki Hori Satoshi Tsutsumi Yukimasa Yasumoto Masanori Ito Michimasa Suzuki Fumine S. Tanaka Shinsuke Kyogoku Masanobu Nakamura Takashi Tabuchi Issei Fukunaga Yuriko Suzuki Koji Kamagata Yoshitaka Masutani Shigeki Aoki | 2014 | Magnetic Resonance Imaging2014，，： | 2 |
| 9 | Achieving the Goals of Healthy China 2030 Depends on Increasing Smoking Cessation in China:Comparative Findings from the ITC Project in China,Japan,and the Republic of Korea显示文摘Summary Tobacco smoking is the number one preventable cause of disease and death in China as it is globally.Indeed,the toll of smoking in China is much greater than its status as the world’s most populous country.There is a persistent and continuing need for China to implement the measures specified in the global tobacco control treaty,the World Health Organization(WHO)Framework Convention on Tobacco Control(FCTC),which China ratified in 2005. | Geoffrey T.Fong Jiang Yuan Lorraine V.Craig Steve Shaowei Xu Gang Meng Anne C.K.Quah Hong-Gwan Seo Sungkyu Lee Itsuro Yoshimi Kota Katanoda Takahiro Tabuchi | 2021 | China CDC weekly2021，3，22： | 2 |
| 10 | Preparation and Characterization of Natural Lower Dimensional Layered Perovskite- type Compounds显示文摘 | Tabuchi Y Asai K Rikukawa M | 2000 | Journal of Physics and Chemistry of Solid2000，61，： | 2 |
| 11 | Evaluation of microstructure and creep damage in high-Cr ferritic steel welds显示文摘11Cr-0.4Mo-2W-CuVNb steel (ASME Gr.122) is used for boiler components in ultra-supercritical (USC) thermal power plants.The creep strength of high-Cr steel welds decreases due to the formation of Type IV creep damage in the heat-affected zone (HAZ) during long-term use at high temperatures.In the present study,the processes and mechanisms of Type IV creep damage were elucidated by investigating the long-term creep strength,microstructure and damage behavior of Gr.122 steel welds.Creep tests using thick welded joints were interrupted at several time steps,and the initiation,evolution and distribution of creep damage were measured.It was found that the formation and growth of creep damage was suppressed during the steady-state stage;creep voids formed at 0.5 of life,and coalesced to form a crack after 0.9 of life.Type IV creep damage was mostly observed in the area about 30% below the surface of the plate.Differences in creep damage behavior between Gr.122 and Gr.91 steel welds were examined.Experimental creep damage distribution was compared with computed versions using the finite element method and damage mechanics. | Masaaki TABUCHI Hiromichi HONGO | 2011 | Acta Metallurgica Sinica(English Letters)2011，24，3： | 2 |
| 12 | Why is the coexistence of gastric cancer and duodenal ulcer rare? Examination of factors related to both gastric cancer and duodenal ulcer显示文摘 | Hideyuki Ubukata Hiroyuki Nagata Takanobu Tabuchi Satoru Konishi Teruhiko Kasuga Takafumi Tabuchi | 2011 | Gastric Cancer2011，，1： | 2 |
| 13 | Z -Phase formation in welded joints of high chromium ferritic steels after long - term creep显示文摘 | K Sawada M Tabuchi H Hongo | 2007 | Mater Characterization2007，，68： | 1 |
| 14 | Study of the capacity fading mechanism for Fe-substitute LiCoO2 positive electrode显示文摘 | Mclaren V L West A R Tabuchi M | 2004 | J Electrochem Soc2004，151，5： | 1 |
| 15 | Intracarotid urokinase with thromboembolic occlusion of the middle cerebral artery显示文摘 | Mori E Tabuchi M Yamadori AI | 1988 | Stroke1988，19，： | 1 |
| 16 | A multiphase model for cold start of polymer electrolyte fuel cells显示文摘 | MAO L WANG C Y TABUCHI Y | 2007 | J of the Electrochemical Society2007，154，3： | 1 |
| 17 | Inhibition of DNA-dependent protein kinase promotes ultrasound-induced cell death including apoptosis in human leukemia cells显示文摘 | Yukihiro Furusawa Yoshisada Fujiwara Mariame Ali Hassan Yoshiaki Tabuchi Akinori Morita Atsushi Enomoto Takashi Kondo | 2012 | Cancer Letters2012，，1： | 1 |
| 18 | Relief of posttonsillectomy pain by release of lidoeaine from fi brin glue 显示文摘 | Kitajiri S Tabuchi K Hiraumi H | 2001 | Laryngoscope2001，111，： | 1 |
| 19 | Preparation of dense LiFePO4/C composite positive electrodes using spark-plasma-sintering process 显示文摘 | Takeuchi T Tabuchi M | 2005 | J Power Sources2005，146，2： | 1 |
| 20 | Creep damage eval- uation of 9Cr-I Mo-V-Nb steel welded joints showing type IV fracture显示文摘 | Watanabe T Tabuchi M Yamazaki M | 2006 | International Journal of Pressure Vessels and Piping2006，，： | 1 |
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