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| 1 | 基本参数法X-射线荧光光谱同时分析镍、钴和铁基合金显示文摘用基本参数法分析了镍、钴和铁基合金,对每种元素在整个含量范围内用单一校准进行了测定,并获得了满意的结果。研究显示,本方法可以采用多通道光谱仪对主次元素进行分析测定。例如,对镍元素来说,在质量分数0%到100%的浓度范围内,准确度达到质量分数0.14%。我们还发现,在铬的分析中,三级激发很显著,对整体强度的贡献率达到2.4%。通过将三级激发考虑进理论强度计算,方法的准确度可由质量分数0.14%提高到0.10%。对灵敏度进行了最小二乘拟合法校准,研究显示二次拟合多项式用单一校准曲线在整个浓度范围内都能给出很好的结果。在多通道光谱仪中,当通道不再适合谱线重叠时,理论强度重叠校正法是有效的手段。 | KATAOKA Yoshiyukki FURUSAWA Eiichi KOHNO Hisayuki ARAI Tomoya MARTIN Al INOUE Hisashi MANTLER Michael | 2009 | 冶金分析2009，29，5： | 9 |
| 2 | Gene expression of CCL8 and CXCL10 in peripheral blood leukocytes during early pregnancy in cows显示文摘Background: The aim of the present study was to evaluate CCL8 and CXCL10 expression and its regulatory mechanism in peripheral blood leukocytes(PBLs) at the time of maternal recognition in cows. Blood samples were collected on 14, 15, 16, 17 and 18 d after artificial insemination(AI). Based on the day of return of estrus, cows were divided into three groups, pregnant(n = 5), early embryonic mortality(EEM; n = 5) and late embryonic mortality(LEM; n = 5). The gene expression levels in PBLs were assessed with quantitative real-time reverse transcription PCR.Results: The expression of CCL8 and CXCL10 mRNA in PBLs gradually increased from 14 to 18 d of pregnant cows and significant differences were observed on 18 d(P < 0.05), whereas no significant changes were observed both in EEM and LEM cows. Interferon-stimulated protein 15 k Da(ISG15), myxovirus-resistance gene(MX) 1 and MX2 mRNA expression in PBLs increased from 14 to 18 d which was significant on 18 d of pregnant cows as well as in LEM cows(P < 0.05), but no changes were observed in EEM cows. To determine whether the expression of CCL8 and CXCL10 in PBLs was regulated by pregnancy-related substances or not, expression level was assessed after exposure to interferon-τ(IFNT) and CCL16. Monocytes, granulocytes and lymphocytes were obtained using density-gradient centrifugation and flow cytometry. The addition of IFNT(100 ng/mL) and CCL16(100 ng/mL) to cultured PBLs increased the expression of CCL8 and CXCL10 mRNA(P < 0.05). The expression of ISG15, MX1 and MX2 mRNA in PBLs was also stimulated by IFNT and CCL16(P < 0.05).Conclusions: The expression of CCL8 and CXCL10 genes increased in PBLs during early pregnancy. Since IFNT stimulated CCL8 and CXCL10 expression in cultured PBLs, the increase of CCL8 and CXCL10 might be pregnancy-dependent events.The expression of both CCL8 and CXCL10 in PBLs was stimulated by CCL16 as wel as IFNT, suggesting a chemokine interaction that at least includes CCL8, CXCL10 and CCL16, and may play a role in regulating maternal recognition in cows. | Ryosuke Sakumoto Kosuke Iga Ken-Go Hayashi Shiori Fujii Hiroko Kanahara Misa Hosoe Tadashi Furusawa | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 3 |
| 3 | Modelocked laser based on ytterbium doped holey fibre显示文摘 | Furusawa K | 2001 | Electrronics Letters2001，37，9： | 2 |
| 4 | Microstructure and performance of biodegradable magnesium alloy tubes fabricated by local-heating-assisted dieless drawing显示文摘Magnesium(Mg)alloy stents are expected to be the next generation of stents because of good biocompatibility and biodegradability.Compared with cold drawing,dieless drawing with local heating is an effective method for manufacturing the Mg alloy microtubes since a large reduction in area can be achieved in a single pass.However,the microstructure and properties of dieless drawn tubes have not been clarified,leading to the problems in practical application of dieless drawn tubes.In this study,the microstructure and performance of dieless drawn tubes are clarified.The results show that temperature and speed in the dieless drawing process are two factors in determining the grain size of dieless drawn tubes since decreasing the temperature or increasing the speed promotes the generation of fine-grained microstructure.Twins are also generated during the dieless drawing process,which 1)disintegrates grains leading to refinement and 2)causes Hall-Petch law effect on dieless drawn tubes.Tensile tests show that grain size is the main factor in determining the mechanical properties of dieless drawn tubes,namely,0.2%proof stress 135-180MPa,ultimate tensile strength(UTS)200-250MPa,and elongation 8-12%.In 0.9 wt%NaCl solution,localized corrosion is the key factor in initiating the corrosion of dieless drawn tubes,but refined grains and fewer twins can alleviate local corrosion.These results imply that dieless drawn tubes are promising in the clinical application of Mg alloy stents for cardiovascular disease. | Peihua Du Shusaku Furusawa Tsuyoshi Furushima | 2020 | Journal of Magnesium and Alloys2020，8，3： | 2 |
| 5 | Unraveling the mystery of enhanced cell-killing effect around the Bragg peak region of a double irradiation source^(9)C-ion beam显示文摘An enhanced cell-killing effect at the penetra- tion depths around the Bragg peak of a β-delayed particle decay 9C-ion beam has been observed in our preceding ra- diobiological experiments in comparison with a therapeutic 12C beam under the same conditions, and RBE values of the 9C beam were revealed to be higher than those of the comparative 12C beam by a factor of up to 2. This study is aimed at investigating the biophysical mechanisms underlying the important experimental phenomenon. First of all, a model for calculating the stopping probability density of the experimentally applied 9C beam is worked out, where all determinants such as the initial momentum spread of the 9C beam, the fluence attenuation with penetration depth due to the projectile-target nuclear reaction and the energy strag- gling effect are taken into account. On the basis of the calcu- lated 9C-ion stopping distribution, it has been found that the area corresponding to the enhanced cell-killing effect of the 9C beam appears at the stopping region of the incident 9C ions. The stopping 9C-ion density in depth, then, is derived from the calculated probability density. Moreover, taking entrance dose 1 Gy for the 9C beam as an example, the aver- age stopping 9C-ion numbers per cell at various depths are deduced. Meanwhile, the mean lethal damage events induced by the 9C and comparative 12C beams at the depths with al- most equal dose-averaged LETs are derived from the meas- ured cell surviving fractions at these depths for the 9C and 12C beams. Under the condition of the same absorbed doses, there are indeed good agreements between the average stop- ping 9C-ion number pre cell and the difference of the mean lethal damage events between the 9C and 12C beams at the depths of similar dose-averaged LETs. It can be inferred that if a 9C ion comes to rest in a cell, the cell would undergo dy- ing. In view of the decay property of 9C nuclide, clustered damage would be caused in the cell by the emitted low-energy particles. Therefore, the results achieved in this work can be taken as indirect evidence supporting that damage cluster is more efficient in leading to cell lethality. | LI Qiang Y. Furusawa M. Kanazawa A. Kitagawa | 2005 | Chinese Science Bulletin2005，50，22： | 2 |
| 6 | Irradiation ofmixed beam and design of spread-out bragg peak for heavy-ion radiotherapy显示文摘 | Kanai T Furusawa Y Fukutsu K | 1997 | Radiat Res1997，147，1： | 1 |
| 7 | Anterior decompression and fusion for cervical myeloradiculopathy secondary to ossification of the posterior ligament 显示文摘 | Baba H Furusawa N Tanaka Y | 1994 | Int Orthop1994，18，： | 1 |
| 8 | Matrix solid-phase dispersion extraction and high-performance liquid chromatographic determination of residual sulfonamides in chicken显示文摘 | Kunihiro Kishida Naoto Furusawa | 2001 | Journal of Chromatography A2001，937，： | 1 |
| 9 | Primary central nervoussystem lymphoma presenting as diffuse cerebral infiltration 显示文摘 | Furusawa T Okamoto K Ito J | 1998 | Radiat Med1998，16，2： | 1 |
| 10 | Cell growth inhibition by membrane active components in brownish scale of onion显示文摘 | FURUSAWA M TSUCHIYA H NAYAYAMA M | 2006 | Journal of Health Science2006，52，5： | 1 |
| 11 | Inhibition of DNA-dependent protein kinase promotes ultrasound-induced cell death including apoptosis in human leukemia cells显示文摘 | Yukihiro Furusawa Yoshisada Fujiwara Mariame Ali Hassan Yoshiaki Tabuchi Akinori Morita Atsushi Enomoto Takashi Kondo | 2012 | Cancer Letters2012，，1： | 1 |
| 12 | Noise measurement by echo integrator显示文摘 | TAKAO Y FURUSAWA M | | 0，，： | 1 |
| 13 | Effect of atorvastatin and etidronate combination therapy on regression of aortic atheroselerotic plaques evaluated by magnetic resonance imaging显示文摘 | Kawahara T Nishikawa M Furusawa T | 2011 | J Atheroscler Thromb2011，18，： | 1 |
| 14 | Concurrent use of granulocyte colony-stimulating factor with low-dose cytosine arabinoside and aclarubicin for previously treated acute myelogenous leukemia: a pilot study显示文摘 | YamadaK FurusawaS SaitoK | 1995 | Leukemia1995，9，1： | 1 |
| 15 | Hetero-Coagulation Behavior of Polymer Latices with Spherical Silica显示文摘 | Furusawa K Anzai C | 1992 | Colloid and Surface1992，63，12： | 1 |
| 16 | Cladding pumped ytterbium-doped fiber laser with holey inner and outer cladding显示文摘 | FURUSAWA K MALINOWSKI A PRICE J H V | 2001 | Ontics Express2001，9，13： | 1 |
| 17 | Effect of flexural rigidity of tool on ma- chining accuracy during microgrooving by ultrosonic vibra- tion cutting method显示文摘 | Toshiaki Furusawa | 2010 | Japanese Joural of Applied Physics2010，，12： | 1 |
| 18 | Imaging of calvarial eosinophil granuloma显示文摘 | K. Okamoto J. Ito T. Furusawa K. Sakai S. Tokiguchi | 1999 | Neuroradiology1999，，10： | 1 |
| 19 | Mi- crocapsule with a heterogeneous catalyst for the methanolysis of rapeseed oil显示文摘 | KURAYAMA F YOSHIKAWA T FURUSAWA T | 2013 | Bioresour Technol2013，135，： | 1 |
| 20 | Development of maternal IgG-free chick obtained from surgically bursectomized hen 显示文摘 | Yasuda M Furusawa S Matsuda K 1998 | 1998 | Comp Immunol Microbiol Infect1998，21，3： | 1 |
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