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| 1 | Pseudocirrhosis in a pancreatic cancer patient with liver metastases: A case report of complete resolution of pseudocirrhosis with an early recognition and management显示文摘We report a case of pseudocirrhosis arising in the setting of regression of liver metastases from pancreatic cancer. A 55-year-old asymptomatic woman presented to our clinic with newly diagnosed metastatic pancreatic cancer with extensive liver metastases. She underwent systemic chemotherapy with gemcitabine and oxaliplatin (GEMOX). After 8 cycles of therapy, she had a remarkable response to the therapy evidenced by decline of carcinoembryonic antigen (CEA) and CA19 by > 50% and nearly complete resolution of hepatic metastases in computed tomography (CT) scan. Shortly after, she developed increasing bilateral ankle edema and ascites, associated with dyspnea, progressive weight gain, and declining performance status. Gemcitabine and oxaliplatin were discontinued as other causes of her symptoms such as congestive heart disease or venous thrombosis were ruled out. CT scan 6 mo after the initiation of GEMOX revealed worsening ascites with a stable pancreatic mass. However, it also revealed a lobular hepatic contour, segmental atrophy, and capsular retraction mimicking the appearance of cirrhosis. She was managed with aggressive diuresis and albumin infusions which eventually resulted in a resolution of the above- mentioned symptoms as well as complete resolution of pseudocirrhotic appearance of the liver and ascites in CT scan. This case demonstrates that pancreatic cancer patients can develop pseudocirrhosis. Clinicians and radiologist should be well aware of this entity asearly recognition and management can lead to a near complete recovery of liver function and much improved quality of life as illustrated in this case. | Soonmo Peter Kang Tamar Taddei Bruce McLennan Jill Lacy | 2008 | World Journal of Gastroenterology2008，14，10： | 4 |
| 2 | Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study显示文摘AIM To increase our insight in the neuronal mechanisms underlying cognitive side-effects of antiepileptic drug(AED) treatment.METHODS The relation between functional magnetic resonance-acquired brain network measures, AED use, and cognitive function was investigated. Three groups of patients with epilepsy with a different risk profile for developing cognitive side effects were included: A 'low risk' category(lamotrigine or levetiracetam, n=16), an 'intermediate risk' category(carbamazepine, oxcarbazepine, phenytoin, or valproate, n=34) and a 'high risk' category(topiramate, n=5). Brain connectivity was assessed using resting state functional magnetic resonance imaging and graph theoretical network analysis. The Computerized Visual Searching Task was used to measure central information processing speed, a common cognitive side effect of AED treatment. RESULTS Central information processing speed was lower in patients taking AEDs from the intermediate and high risk categories, compared with patients from the low risk category. The effect of risk category on global efficiency was significant(P < 0.05, ANCOVA), with a significantly higher global efficiency for patient from the low category compared with the high risk category(P < 0.05, post-hoc test). Risk category had no significant effect on the clustering coefficient(ANCOVA, P > 0.2). Also no significant associations between information processing speed and global efficiency or the clustering coefficient(linear regression analysis, P > 0.15) were observed. CONCLUSION Only the four patients taking topiramate show aberrant network measures, suggesting that alterations in functional brain network organization may be only subtle and measureable in patients with more severe cognitive side effects. | Tamar M van Veenendaal Dominique M IJff Albert P Aldenkamp Richard H C Lazeron Paul A M Hofman Anton J A de Louw Walter H Backes Jacobus F A Jansen | 2017 | World Journal of Radiology2017，9，6： | 2 |
| 3 | Trends in Management and Outcome of Hospitalized Patients With Acute Stroke and Transient Ischemic Attack: The National Acute Stroke Israeli (NASIS) Registry显示文摘 | David Tanne Silvia Koton Noa Molshazki Uri Goldbourt Tamar Shohat Rakefet Tsabari Ehud Grossman Natan M. Bornstein | 2012 | Stroke2012，，： | 2 |
| 4 | At Long Last: Evidence for Pexophagy in Plants显示文摘 | Tamar Avin-Wittenberg Alisdair R. Fernie | 2014 | Molecular Plant2014，7，8： | 2 |
| 5 | Locomotion, assessment, and regulatory fit: Value transfer from “how” to “what”显示文摘 | Tamar Avnet E Tory Higgins | 2003 | Journal of Experimental Social Psychology2003，，5： | 2 |
| 6 | A study of edge detection algorithms显示文摘 | Tamar Peli David Malah | 2009 | Computer Graphics and Image Processing2009，20，1： | 1 |
| 7 | Gradually internationalizing 'born global' firms, an oxymoron?显示文摘 | Niron Hashai and Tamar Almor | 2004 | International Business Review2004，13，： | 1 |
| 8 | On the effectofa pificularin detoxifying substance ferulic acid on the tissue resistance office plants to the blastfungal infection显示文摘 | TAMAR | 1996 | Ann Phytopath Soc Japan1996，32，： | 1 |
| 9 | A semantic analysis of addition and subtraction word problems in arithmetic显示文摘 | Pearla Nesher Tamar Katriel | 1977 | Educational Studies in Mathematics1977，，3： | 1 |
| 10 | Antiproliferative effect of thalidomide alone and combined with carmusitine against C6 rat glioma显示文摘 | Arrieta O Guevara P Tamarize J | 2002 | Int J Exp Pathol2002，83，2： | 1 |
| 11 | Morphology-based algorithm for point target detection in infrared background显示文摘 | Victor T T Tamar P | 1993 | Proceedings of SPIE1993，1954，： | 1 |
| 12 | Stabihty and chang in curriculum evaluation显示文摘 | Tamar Levine | 2002 | studies in educational evaluation2002，，28： | 1 |
| 13 | Promises of novel multi-target neuroprotective and neurorestorative drugs for Parkinson's disease显示文摘 | Moussa BHY Lana K Tamar A | 2014 | Parkinsonism Relat Disord2014，45，20： | 1 |
| 14 | Characterization of the envelope protein of pseudorabies virus 显示文摘 | Hartmut Hampl Tamar Ben-porat Lorentz Ehrlicher | 1984 | J Virol1984，12，2： | 1 |
| 15 | Introduction:Approaches to the Informal Economy显示文摘 | Tamar Wilson | 2011 | Urban Anthropology2011，，34： | 1 |
| 16 | Polymer-drug conjugates: progress in polymeric prodrugs 显示文摘 | KHANDARE J TAMAR A | 2006 | Prog Polym Sci2006，31，4： | 1 |
| 17 | Neurological mechanisms of green tea polyphenols inAlzheimer's and Parkinson's diseases显示文摘 | Orly W Silvia M Tamar A | 2004 | J Nutri Biochem2004，15，： | 1 |
| 18 | Effectiveness of vitamin B(12)in treating recurrent aphtbous stomatitis a randomized,double-blind,placebo-controlled trial显示文摘 | Ilia Volkov Inna Bndoy Tamar Freud | 2009 | J Am Board Fam Med2009，22，： | 1 |
| 19 | Is obesity a risk factor for psychopathology among adolescents? 显示文摘 | Erermis S Cetin N Tamar M | 2004 | Pediatr Int2004，46，3： | 1 |
| 20 | Temperature effects on photosynthetic capacity,respiraton and growth rates of bloom-forming cyanobacteria显示文摘 | RICHARD D R TAMAR Z | 1987 | New Zealand Journal of Marine and Freshwater Research1987，21，： | 1 |
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