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| 1 | Endothelial-specific m^6A modulates mouse hematopoietic stem and progenitor cell development via Notch signaling显示文摘 | Junhua Tv Yifan Zhang Suwei Gao Chunxia Zhang Yusheng Chen Wei Li Yun-Gui Yang Qi Zhou Feng Liu | 2018 | Cell Research2018，28，2： | 12 |
| 2 | An atypical component of RNA-directed DNA methylation machinery has both DNA methylation-dependent and -independent roles in locus-specific transcriptional gene silencing显示文摘指导 RNA 的 DNA methylation (RdDM ) 是在植物的一条重要 de novo DNA methylation 小径。RdDM 调停许多内长的 genomic loci,其大多数是联系的 transposon 的 transcriptional silencing。一幅前面的遗传屏幕在 Arabidopsis 为 RdDM 作为一个新部件识别了 DTF1 (DNA 有约束力的抄写因素 1 ) 。在 DTF1 的 Loss-of-function 变化释放 RdDM 目标 loci 的 transcriptional silencing 并且减少 24-nt 的累积从一些目标的小介入 RNA (siRNAs ) 。在 dtf1 异种植物,有趣地,在 solo-LTR 的 transcriptional 基因 silencing 的版本被减少的 siRNA 累积然而并非由减少的 DNA methylation 伴随。这些结果建议 DTF1 是 RdDM 的一个不正常的部件并且在 transcriptional 基因 silencing 有 methylation 依赖的两 DNA 和独立角色。我们建议除 DNA methylation 以外, siRNAs 可以引起某另外的 uncharacterized 导致 transcriptional 基因 silencing 的 epigenetic 修正。 | Jun Liu Ge Bai Cuijun Zhang Wei Chen Jinxing Zhou Suwei Zhang Qing Chen Xin Deng Xin-Jian He Jian-Kang Zhu | 2011 | Cell Research2011，21，12： | 6 |
| 3 | Particulate matter pollution in Kunshan High-Tech zone: Source apportionment with trace elements, plume evolution and its monitoring显示文摘Particulate matter(PM) in the Kunshan High-Tech zone is studied during a three-month campaign. PM and trace elements are measured by the online pollution monitoring, forecastwarning and source term retrieval system AS3. Hourly measured concentrations of PM_(10), PM_(2.5) and 16 trace elements in the PM_(2.5) section(Ca, Pb, Cu, Cl, V, Cr, Fe, Ti, Mn, Ni, Zn, Ga, As, Se, Sr, Ba)are focused. Source apportionment of trace elements by Positive Matrix Factorization modeling indicates that there are five major sources, including dust, industrial processing, traffic,combustion, and sea salt with contribution rate of 23.68%, 21.66%, 14.30%, 22.03%, and 6.89%,respectively. Prediction of plume dispersion from concrete plant and traffic emissions shows that PM_(10) pollution of concrete plant is three orders of magnitude more than that of the traffic. The influence range can extend to more than 3 km in 1 hr. Because the footprint of the industrial plumes is constantly moving according to the local meteorological conditions, the fixed monitoring sites scattered in a few hundred meters haven't captured the heaviest pollution plume at the local scale of a few km^2. As a more intensive monitoring network is not operationally possible, the use of online modeling gives accurate and quantitative information of plume location, which increases the spatial pollution monitoring capacity and improves the understanding of measurement data. These results indicate that the development of the AS3 system, which combines monitoring equipment and air pollution modeling systems, is beneficial to the real-time pollution monitoring in the industrial zone. | Suwei Zhang Qijie Zhang Armand Albergel Didier Buty Liangmin Yu Haiting Wang Wuxia Bi Peng Cheng Fu Chen Jun Fang Ruirui Hou Xudong Luan Changgan Shu Jingjing Su | 2018 | Journal of Environmental Sciences2018，30，9： | 3 |
| 4 | Steroids and triterpenoids of Antrodia cinnamomea-A fungi parqasitic on cinnamomum microranthum显示文摘 | Shen Yuanchu Chen Changhang | 1996 | Phytochemistry1996，41，5： | 1 |
| 5 | Gradual Evolution from Fluvial Dominated to Tide Dominated Deltas and Channel Type Transformation: A Case Study of MPE3 Block in the Orinoco Heavy Oil Belt of the Eastern Venezuelan Basin显示文摘Based on the data of core description and sporopollen analysis,the gradual evolution of deltas in vertical direction and transition of channel types in the MPE3 block of the eastern Venezuela Basin have been surveyed by seismic phase and well logging facies interpretation.The results show that due to the great sea level rise,the sedimentary system of the Miocene Oficina Formation in the MPE3 block shifted from the distal-source sandy braided river delta to tide-affected delta,and eventually to tide-dominated delta.Vertically,during the early stage of sedimentation of Oficina Formation,the distributary channels of the delta were dominated by braided river channels.While in the later stage,as the tidal effect was gradually intensified,the channel changed from braided channel to meandering channel.On plane,as a result of differential transgression,sedimentary framework and distribution of sand bodies vary across the study area.Compared with the eastern part,the western part has more braided channels,larger channel bars,less developments of distributary bay and higher ratio of sand to mud.Whereas the braided channels in the south are larger than those in the north.It is the first time we pointed out the impact of marine transgression differences on the sedimentary facies distribution and river type transition in the study area.Factors like the structural and paleogeomorphological change,sea level variation,supply of sediments have strong influence on the evolution of sedimentary system and distribution of sandbodies.It is predicted that the major sandbody is more developed in the central south,which can guide the subsequent horizontal well development. | HUANG Wensong CHEN Heping XU Fang MENG Zheng ZHANG Fanqin WU Suwei | 2019 | Acta Geologica Sinica(English Edition)2019，93，6： | 1 |
| 6 | Tourmaline geochemistry and boron isotopic variations as a guide to fluid evolution in the Qiman Tagh W-Sn belt, East Kunlun, China显示文摘The Qiman Tagh W-Sn belt lies in the westernmost section of the East Kunlun Orogen, NW China, and is associated with early Paleozoic monzogranites, tourmaline is present throughout this belt. In this paper we report chemical and boron isotopic compositions of tourmaline from wall rocks, monzogranites, and quartz veins within the belt, for studying the evolution of ore-forming fluids. Tourmaline crystals hosted in the monzogranite and wall rocks belong to the alkali group, while those hosted in quartz veins belong to both the alkali and X-site vacancy groups. Tourmaline in the walk rocks lies within the schorl-dravite series and becomes increasingly schorlitic in the monzogranite and quartz veins. Detrital tourmaline in the wall rocks is commonly both optically and chemically zoned,with cores being enriched in Mg compared with the rims. In the Al-Fe-Mg and Ca-Fe-Mg diagrams,tourmaline from the wall rocks plots in the fields of Al-saturated and Ca-poor metapelite, and extends into the field of Li-poor granites, while those from the monzogranite and quartz veins lie within the field of Li-poor granites. Compositional substitution is best represented by the MgFe_(-1), Al(NaR)_(-1), and AlO(Fe(OH))_(-1) exchange vectors. A wider range of δ^(11)B values from -11.1‰ to -7.1‰ is observed in the wall-rock tourmaline crystals, the B isotopic values combining with elemental diagrams indicate a source of metasediments without marine evaporates for the wall rocks in the Qiman Tagh belt. The δ^(11)B values of monzogranite-hosted tourmaline range from -10.7‰ and-9.2‰, corresponding to the continental crust sediments, and indicate a possible connection between the wall rocks and the monzogranite. The overlap in δ^(11)B values between wall rocks and monzogranite implies that a transfer of δ^(11)B values by anataxis with little isotopic fractionation between tourmaline and melts. Tourmaline crystals from quartz veins have δ^(11)B values between -11.0‰ and-9.6‰, combining with the elemental diagrams and geological features, thus indicating a common granite-derived source for the quartz veins and little B isotopic fractionation occurred. Tourmalinite in the wall rocks was formed by metasomatism by a granite-derived hydrothermal fluid, as confirmed by the compositional and geological features.Therefore, we propose a single B-rich sedimentary source in the Qiman Tagh belt, and little boron isotopic fractionation occurred during systematic fluid evolution from the wall rocks, through monzogranite, to quartz veins and tourmalinite. | Zhen Zheng Yanjing Chen Xiaohua Deng Suwei Yue Hongjin Chen Qingfei Wang | 2019 | Geoscience Frontiers2019，10，2： | 1 |
| 7 | Decreased miRNA-148a is associated with lymph node metastasis and poorclinical outcomes and functions as a suppressor of tumor metastasis in non-smallcell lung cancer显示文摘 | Yong Chen Lingfeng Min Xizhi Zhang Suwei Hu Buhai Wang Wei Liu Rui Wang Xuewen Gu Weigan Shen Houning Lv Jing Zou Yuexiang Chen Xingxiang Xu Longbang Chen | 2013 | Oncology Reports2013，，4： | 1 |
| 8 | Development of SLS fuel cell current collectors 显示文摘 | CHEN Suwei MURPHY J HERLEHY J | 2006 | Rapid Prototyping Journal2006，12，5： | 1 |
| 9 | Antioxidant properties of aspirin: Characterization of the ability of aspirin to inhibit silica-induced lipid peroxidation, DNA damage, NF-κB activation, and TNF-α production显示文摘 | Xianglin Shi Min Ding Zigang Dong Fei Chen Jiangping Ye Suwei Wang Stephen S. Leonard Vince Castronova Val Vallyathan | 1999 | Molecular and Cellular Biochemistry (-)1999，，1： | 1 |
| 10 | Phase transition and piezoelectric property of (Ag,K)NbO_(3) ceramics显示文摘AgNbO_(3) is an antiferroelectric (AFE) material with double hysteresis loop. Both the antiferroelectricityand ferroelectricity can be enhanced by doping. Herein, the ferroelectricity of AgNbO_(3) ceramics wasenhanced via K-doping and the phase diagram of the (Ag_(1-x)K_(x))NbO_(3) ceramics was upgraded. In details,(Ag_(1-x)K_(x))NbO_(3) ceramics are ferrielectric (FIE) M1 phase as x=5.00-5.50 mol% and ferroelectric (FE) Ophase as x=5.75-6.00 mol% before poling, and FE O phase as x=5.00-6.00 mol% after poling at roomtemperature. With increasing temperature, (Ag_(1-x)K_(x))NbO_(3) ceramics show the phase evolutions from FIEM1, AFE M2 to paraelectric (PE) T phase at x=5.00-5.50 mol% and from FE O, FE T to PE T phase at x=5.75-6.00 mol% before poling, and from FE O, FE T to PE T phase at x=5.00-6.00 mol% after poling.High d33 values of 180 pC/N and 285 pC/N are obtained at the FE O-FE T and FE T-PE T phase boundaries.This work sheds light on a novel and promising lead-free piezoelectric system. | Lin Chen Mingyuan Zhao Jing Wang Suwei Zhang Fuhua Sun Lei Zhao | 2022 | Journal of Materiomics2022，8，4： | 0 |
| 11 | Rationally designed ultrathin Ni(OH)_(2)/titanate nanosheet heterostructure for photocatalytic CO_(2) reduction显示文摘Dye-sensitized photocatalysis has been extensively studied for photocatalytic solar energy conversion due to the advantage in capturing long-wavelength photons with a high absorption coefficient.The rational integration of photosensitizer with semiconductor and cocatalyst to collaboratively operate in one system is highly desired.Here,we fabricate a Ni(OH)_(2)-loaded titanate nanosheet(Ni(OH)_(2)/H_(2)Ti_(6)O_(13))composite for high-performance dye-sensitized photocatalytic CO_(2) reduction.The ultrathin H_(2)Ti_(6)O_(13) nanosheets with negative surface charge provide an excellent support to anchor the dye photosensitizer,while the loaded Ni(OH)2 serves as an adsorbent of CO_(2) and electron sink of photoelectrons.As such,the photoelectrons derived from the[Ru(bpy)3]Cl_(2) sensitizer can be targeted transfer to the Ni(OH)_(2) active sites via the H_(2) Ti_(6)O_(13) nanosheets linker.A high CO production rate of 1801μmol g^(-1) h^(-1) is obtained over the optimal Ni(OH)_(2)/H_(2)Ti_(6)O_(13),while the pure H_(2)Ti_(6)O_(13) shows significantly lower CO_(2) reduction performance.The work is anticipated to trigger more research attention on the rational design and synthesis of earth-abundant transition metal-based cocatalysts decorated on ultrathin 2D platforms for artificially photocatalytic CO_(2) reduction. | Wanru Liao Suwei Lu Weihang Chen Shuying Zhu Yuzhou Xia Min-Quan Yang Shijing Liang | 2022 | Green Chemical Engineering2022，3，3： | 0 |
| 12 | The Anzhen Risk Scoring System for Acute Type A Aortic Dissection:A Prospective Observational Study Protocol显示文摘Introduction:Acute type A aortic dissection(ATAAD)is a catastrophic disease with fatal outcomes.Malperfusion syndrome(MPS)is a serious complication of ATAAD,with an incidence of 20–40%.Many studies have shown that MPS is the main risk factor for poor ATAAD prognosis.However,a risk scoring system for ATAAD based on MPS is lacking.Here,we designed a risk scoring system for ATAAD to assess mortality through quantitative assessment of relevant organ malperfusion and subsequently develop rational treatment strategies.Methods and analysis:This was a prospective observational study.Patients’perioperative clinical data were col-lected to establish a database of ATAAD(N≥3000)and determine whether these patients had malperfusion complica-tions.The Anzhen risk scoring system was established on the basis of organ malperfusion by using a random forest survival model and a logistics model.The better method was then chosen to establish a revised risk scoring system.Ethics and dissemination:This study received ethical approval from the Ethics Committees of Beijing Anzhen Hospital,Capital Medical University(KS2019034-1).Patient consent was waived because biological samples were not collected,and no patient rights were violated.Findings will be disseminated at scientific conferences and in peer-reviewed publications. | Bo Jia Cheng Luo Chengnan Li Yipeng Ge Yongliang Zhong Zhiyu Qiao Haiou Hu Suwei Chen Junming Zhu | 2023 | Cardiovascular Innovations and Applications2023，7，1： | 0 |
| 13 | Recent advances in chemical protein synthesis:method developments and biological applications显示文摘The central dogma of modern biology underscores the pivotal roles proteins play in diverse biological processes,the study of which necessitates advanced methods to produce proteins with precision and versatility.Chemical protein synthesis,a powerful approach utilizing chemical reactions for the de novo construction of structurally accurate proteins,has emerged as a transformative tool for studying proteins and generating protein derivatives/mimics inaccessible by natural biological machinery,including post-translationally modified proteins,proteins comprised of unnatural amino acids,as well as mirror-image proteins.This review summarizes recent strides in synthetic method developments for chemical protein synthesis,including innovative techniques in solid-phase peptide synthesis,the challenges presented by difficult sequences in either synthesis or folding and the exploration of novel ligation reactions using both chemical and enzymatic methods.Furthermore,the review also delves into newly developed protocols for site-selective protein modifications and the generation of stapled or macrocyclized peptides/miniproteins,highlighting the power of chemical methods to make structurally diverse proteins.Recent applications of synthetic proteins in investigating post-translational modifications(phosphorylation,lipidation,glycosylation,ubiquitination,etc.),mirror-image biological processes and drug development are further discussed.Together,these topics provide a comprehensive overview of the current landscape of chemical protein synthesis. | Suwei Dong Ji-Shen Zheng Yiming Li Huan Wang Gong Chen Yongxiang Chen Gemin Fang Jun Guo Chunmao He Honggang Hu Xuechen Li Yanmei Li Zigang Li Man Pan Shan Tang Changlin Tian Ping Wang Bian Wu Chuanliu Wu Junfeng Zhao Lei Liu | 2024 | Science China Chemistry2024，67，4： | 0 |
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