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| 1 | Collision Tectonics between the Tarim Block(Basin)and the Northwestern Tibet Plateau:New Observations from a Multidisciplinary Geoscientific Investigation in the Western Kunlun Mountains显示文摘New results from deep seismic reflection profiling, wide-angle reflection-refraction profiling and broadband seismic experiments reveal that a series of south-dipping reflectors occur on the southern margin of the Tarim block (basin). However, it is these south-dipping structures that are intercepted by another series of north-dipping reflectors at depths from 30 to about 150 km beneath the foreland of the W Kunlun Mountains. No evidence from the above geophysical data as well as geochemical and surface geological data indicate the southward subduction of the Tarim block beneath the W Kunlun Mountains (NW Tibet plateau), forming the so-called “two-sided subduction” model for the Tibet plateau as proposed by previous studies. So the authors infer that the tectonic interaction between the Tarim block and the W Kunlun block was chiefly affected by a “horizontal compression in opposite directions”, which brought about “face-to-face contact” between these two lithospheric blocks and led to the thickening, shortening and densifying of the lithosphere. Hence a “delamination” was formed due to the gravitational instability created by the thickening and densifying; then alkaline basic volcanic rocks (mainly shoshonite series) was erupted along the northern margin of the Tibet plateau owing to the delamination. This inference for the formation of the alkaline basic volcanics has been confirmed by recent geochemical and petrological studies in Tibet, indicating that different contacts control different magmatic activities: the alkali basalts are always developed in the “horizontal shortening boundary (contact)” on the northern margin of the Tibet plateau, while the muscovite granite and two-mica granite (leucogranite) in the “subductional contact” on the southern margin of the Tibet plateau. | XIAO Xuchang LIU Xun GAO Rui Houn KAO LUO Zhaohua | 2001 | Acta Geologica Sinica(English Edition)2001，75，2： | 19 |
| 2 | Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins显示文摘Members of the RAS proto-oncogene superfamily are indispensable molecular switches that play critical roles in cell proliferation, differentiation, and cell survival. Recent studies have attempted to prevent the interaction of RAS/GTP with RAS guanine nucleotide exchange factors(GEFs), impair RASeffector interactions, and suppress RAS localization to prevent oncogenic signalling. The present study aimed to investigate the effect of the natural triterpenoic acid inhibitor glycyrrhetinic acid, which is isolated from the roots of Glycyrrhiza plant species, on RAS stability. We found that glycyrrhetinic acid may bind to the P-loop of RAS and alter its stability. Based on our biochemical tests and structural analysis results, glycyrrhetinic acid induced a conformational change in RAS. Meanwhile, glycyrrhetinic acid abolishes the function of RAS by interfering with the effector protein RAF kinase activation and RAS/MAPK signalling. | Yuan Zhang Zhihua Wang Xiaoyao Ma Shengnan Yang Xueyan Hu Jin Tao Yuanyuan Houn Gang Bai | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 7 |
| 3 | Ionizaition of chlorine nitrate on ice at 180 K 显示文摘 | SODEAU J R HOUN A B BANHAM S F | 1995 | Phys Chem1995，99，： | 1 |
| 4 | Screening mammography in community practice: positive predictive value of abnormal find- ings and yield of follow-up diagnostic procedures 显示文摘 | Brown ML Houn F Sickles EA | 1995 | AJR Am J Roentgenology1995，165，6： | 1 |
| 5 | Competencies for glob- al heath graduate education显示文摘 | Ca|houn G Spencer HC Buekens P | 2011 | Infect Dis Clin North Am2011，25，3： | 1 |
| 6 | Screening Mam- mography in community practice 1 positive predictive value of abnormal findings and yield of diagnostic procedures 显示文摘 | Brown ML Houn F Sickles EA | 1995 | Am J Roentgenol1995，165，： | 1 |
| 7 | Management of severe traumatic brain injury by decompressive cranectomy显示文摘 | Muunch E Houn P Schurer A | 2000 | Neurosurgery2000，47，： | 1 |
| 8 | Synthesis of nanostructttre γ- alumina with a cationic sttrfactant and controlled amounts of water显示文摘 | Hyun Chul Lee Hae Jin Kim Chang Houn Rhee | 2005 | Microporous and Mesoporous Materials2005，79，13： | 1 |
| 9 | Rice OsHKT2 : 1 transporter mediates large Na+ influx component into K ^+ -starved roots for growth显示文摘 | Tomoaki Horie Alex Costa Tae Houn Kim | 2007 | The EMBO Journal2007，26，12： | 1 |
| 10 | Screening mammography in community practice: positive predictive value of abnormal findings and yield of follow-up diagnostic procedures显示文摘 | Brown ML Houn F Sickels EA | 1995 | A JR1995，16，： | 1 |
| 11 | Synthesis of nanostructure γ- alumina with a cationic surfactant and controlled amounts of water显示文摘 | Lee Hyun Chul Kim Hae Jin Rhee Chang Houn | 2005 | Micropor Mesopor Mater2005，79，13： | 1 |
| 12 | Expansion of a novel CAG frinucleotide repeat in the S'region of PPP2R2B is associated with SCA12显示文摘 | Hounes SE O'Hearn EF McInnis MG | | 0，，： | 1 |
| 13 | Giant multilocular prostatic cystadenoma presenting with obstructive aspermia 显示文摘 | Jong-Pil Park Nam Houn Cho Young Tack Oh | 2007 | Yonsei Medical Journal2007，48，3： | 1 |
| 14 | Noninflammatory chronicpelvic pain syndrome s immunological study in blood, ejaculate- and prostate tissue显示文摘 | John H Barg houn A FunkeG | 2001 | Eur Urol2001，39，1： | 1 |
| 15 | Decreased miRNA-148a is associated with lymph node metastasis and poorclinical outcomes and functions as a suppressor of tumor metastasis in non-smallcell lung cancer显示文摘 | Yong Chen Lingfeng Min Xizhi Zhang Suwei Hu Buhai Wang Wei Liu Rui Wang Xuewen Gu Weigan Shen Houning Lv Jing Zou Yuexiang Chen Xingxiang Xu Longbang Chen | 2013 | Oncology Reports2013，，4： | 1 |
| 16 | Management of severe traumatic brain injury by decompressive craniotomy显示文摘 | Muunch E Houn P Schurer A | 2000 | Neurosurgery2000，47，4： | 1 |
| 17 | Managing the teratogenic risk of thalidomide and J enalidomide: an industry perspective显示文摘 | Bwire R Freeman J Houn F | | Expert Opin Drug Saf0，10，1： | 1 |
| 18 | Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, doublebling trial显示文摘 | Ballantyne C M Houn J Notarbartolo A | 2003 | Circulation2003，107，19： | 1 |
| 19 | Pilot study of mass screening for Wilson's disease in Korea显示文摘 | Si Houn Hahn Soo Young Lee Young-Ju Jang | 2002 | Molecular Genetics and Metabolism2002，76，2： | 1 |
| 20 | Impairedsonichedgehogpathwaycontributestocardiacdysfunctionintype1diabeticmicewithmyocardialinfarction显示文摘 | XiaoQ HouN WangYP etal | 2012 | CardiovascRes2012，95，4： | 1 |
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