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144篇 您的检索式：作者名="Sumii"

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	题名	作者	年代	出处	被引量
1	Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis显示文摘AIM:To investigate the clinical significance of mucosal expression of suppressors of cytokine signaling 1 (SOCS1) and SOCS3 in human ulcerative colitis (UC). METHODS:Biopsy specimens for histological analysis and mRNA detection were obtained endoscopically from the rectum of 62 patients with UC (36 men; age 13-76 years). The patients were classified endoscopically according to Matts' grade (grade 1 to 4). Expression of SOCS1 and SOCS3 mRNAs was quantified in samples by competitive reverse transcription-polymerase chain reaction (RT-PCR). GAPDH was used as an internal control for efficiency of RT-PCR and amount of RNA. RESULTS:SOCS3 mRNA expression was significantly higher in inflamed mucosa of UC than in inactive mucosa. The level of expression was well correlated with the degree of both endoscopic and histologic inflammation. Interestingly,among the patients in remission,the group with relatively low expression of SOCS3 showed a higher rate of remission maintenance over a 12-mo period. In contrast,SOCS1 mRNA was expressed in both inflamed and non-inflamed colonic mucosa and was not correlated with the activity of colonic mucosa or prognosis. CONCLUSION:These observations suggest that increased expression of mucosal SOCS3,but not of SOCS1,may play a critical role in the development of the colonic inflammation of UC.	Yoshihiro Miyanaka Yoshitaka Ueno Shinji Tanaka Kyoko Yoshioka Tsuyoshi Hatakeyama Masaru Shimamoto Masaharu Sumii Kazuaki Chayama	2007	World Journal of Gastroenterology2007，13，21：	2
2	Selective etching of GaN polar surface in potassium hydroxide solutionstudied by x- ray photoelectron spectroscopy显示文摘	Dongsheng Li Sumiy M Fuke S	2001	Journal of Applied Physics2001，90，8：	1
3	Correlation of ratio of serum pepsinogen Ⅰ and Ⅱ with prevalence of gastric cancer and adenoma in Japanese subjects显示文摘	Yoshihara M Sumii K Haruma K	1998	Am J Gastroenterol1998，93，：	1
4	Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caapase activation and oxidative stress 显示文摘	Wang XY Mori T Sumii T	2002	Stroke2002，33，7：	1
5	Autoimmune Pancreatitis as a New Clinical Entity (Three Cases of Autoimmune Pancreatitis with Effective Steroid Therapy)显示文摘	Tetsuhide Ito Itsuro Nakano Shujiro Koyanagi Toshihiko Miyahara Yoshikatsu Migita Keiichiro Ogoshi Hironori Sakai Shizu Matsunaga Osamu Yasuda Toshihiko Sumii Hajime Nawata	1997	Digestive Diseases and Sciences1997，，7：	1
6	Thermal expansion coefficient of titanium casting 显示文摘	Low D Sumii T Swain M	2001	J Oral Rehabil2001，28，3：	1
7	Influence of type 2 diabetes mellitus on cardiovascular disease mortality: findings from the Hawaii-Los Angeles, Hiroshimta Study 显示文摘	Imazu M Sumii K Yamamoto H	2002	Diabetes Res Clin Pract2002，57，1：	1
8	Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia显示文摘	Sumii T Fini ME	2001	Neuroreport2001，12，：	1
9	Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia显示文摘	Asahi M Sumii T Fini M E	2001	Neuroreport2001，12，13：	1
10	Comparison of the bonding strength of porcelain with different bonding systems and alloys as measured by interfacial toughness 显示文摘	Yamada K Suansuwan N Sumii T	2001	J of Dent Res2001，80，：	1
11	Matrix metalloproteinase 2 gene knockout tins no effect on acute brain injury after focal ischemia显示文摘	Asahi M Sumii T Fini ME Itohara S Lo EH	2001	Neuroreport2001，12，13：	1
12	Znvolement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats 显示文摘	Sumii T Lo EH	2002	Stroke2002，33，3：	1
13	Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats 显示文摘	Aoki T Sumii T Mori T	2002	Stroke2002，33，11：	1
14	Evaluation of tumor growth rate in patients with early gastric carcinoma of the elevated type显示文摘	Ken Haruma Takehiko Suzuki Toshitaka Tsuda Masaharu Yoshihara Koji Sumii Goro Kajiyama	1991	Gastrointestinal Radiology1991，，1：	1
15	Blood - brain barrier disruption and matrix metalloproteinase - 9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats显示文摘	AOKI T SUMII T MORI T	2002	Stroke2002，33，：	1
16	Thermal Expansion coefficient of titanium casting显示文摘	Low D Sumii T Swain M	2001	Journal of Oral Rehabilitation2001，28，3：	1
17	Helicobacter pylori-associated gastritis is related to babA2 expression without heterogeneity of the 3 region of the cagA genotype in gastric biopsy specimens显示文摘	Xie XF Ito M Sumii M	2007	Pathobiology2007，74，5：	1
18	Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats 显示文摘	Sumii T Lo EH	2002	Stroke2002，33，3：	1
19	Prediction of short and intermediate-term prognoses of patients with acute myocardial infarction using myocardial contrast echo cardiography one day after recanalization显示文摘	SAKUMA T HAYASHI Y SUMII K	1998	JACC1998，32，6：	1
20	Serum pepsinogen in screening for gastric cancer显示文摘	Kodoi A Yoshihara M Sumii K	1995	J Gastroenterol1995，30，4：	1

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