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| 1 | Tool Life and Surface Integrity in High-speed Milling of Titanium Alloy TA15 with PCD/PCBN Tools显示文摘Titanium alloys are widely used in aeronautics that demand a good combination of high strength, good corrosion resistance and low mass. The mechanical properties lead to challenges in machining operations such as high process temperature as well as rapidly increasing tool wear. The conventional tool materials are not able to maintain their hardness and other mechanical properties at higher cutting temperatures encountered in high speed machining. In this work, the new material tools, which are polycrystalline diamond (PCD) and polycrystalline cubic boron nitride (PCBN) tools, are used in high-speed milling of Ti-6.5Al-2Zr-1Mo-1V (TA15) alloy. The performance and wear mechanism of the tools are investigated. Compared to PCBN tool, PCD tool has a much longer tool life, especially at higher cutting speeds. Analyses based on the SEM and EDX suggest that attrition, adhesion and diffusion are the main wear mechanisms of PCD and PCBN tools in high-speed milling of TA15. Oxidation wear is also observed at PCBN tool/workpiece interface. Roughness, defects, micro-hardness and microstructure of the machined surface are investigated. The recorded surface roughness values with PCD/PCBN tools are bellow 0.3 μm at initial and steady cutting stage. Micro-hardness analysis shows that the machined surface hardening depth with PCD and PCBN tools is small. There is no evidence of sub-surface defects with PCD and PCBN tools. It is concluded that for TA15 alloy, high-speed milling can be carried out with PCD/PCBN tools. | SU Honghua LIU Peng FU Yucan XU Jiuhua | 2012 | Chinese Journal of Aeronautics2012，25，5： | 39 |
| 2 | Cold expansion technology of connection holes in aircraft structures:A review and prospect显示文摘As one kind of key anti-fatigue manufacture approaches with simplicity and effectiveness, the hole cold expansion technology satisfies the increasing needs for light weight and durability of aircraft structures.It can improve the fatigue life by several times at no additional weight conditions.The hole cold expansion technology has been widely used in manufacturing and repairing of both fighters and commercial aircraft, and has become a research hotspot in the strengthening technology.In recent years, hole cold expansion process methods, residual stress around expanded holes, the behavior of fatigue crack initiation and propagation, and fatigue lives after cold expansion are researched extensively through lots of experiments and finite element simulations.A review on the hole cold expansion technology research status in the last twenty years is presented in this paper.Via the analysis of the current characteristics and defects of the hole cold expansion technology, combined with the actual needs in design and manufacture of new-generation aircraft, development trends and novel research directions are presented for realizing precise and high-efficiency anti-fatigue manufacture. | Fu Yucan Ge Ende Su Honghua Xu Jiuhua Li Renzheng | 2015 | Chinese Journal of Aeronautics2015，28，4： | 31 |
| 3 | Duck egg drop syndrome virus:an emerging Tembusu-related flavivirus in China显示文摘Duck egg drop syndrome virus(DEDSV) is a newly emerging pathogenic flavivirus isolated from ducks in China.DEDSV infection mainly results in severe egg drop syndrome in domestic poultry,which leads to huge economic losses.Thus,the discovery of ways and means to combat DEDSV is urgent.Since 2010,a remarkable amount of progress concerning DEDSV research has been achieved.Here,we review current knowledge on the epidemiology,symptomatology,and pathology of DEDSV.A detailed dissection of the viral genome and polyprotein sequences,comparative analysis of viral antigenicity and the corresponding potential immunity against the virus are also summarized.Current findings indicate that DEDSV should be a distinct species from Tembusu virus.Moreover,the adaption of DEDSV in wildlife and its high homology to pathogenic flaviviruses(e.g.,West Nile virus,Japanese encephalitis virus,and dengue virus),illustrate its reemergence and potential to become a zoonotic pathogen that should not be overlooked.Detailed insight into the antigenicity and corresponding immunity against the virus is of clear significance for the development of vaccines and antiviral drugs specific for DEDSV. | LIU PeiPei LU Hao LI Shuang WU Ying George Fu GAO SU JingLiang | 2013 | Science China(Life Sciences)2013，56，8： | 28 |
| 4 | A mouse model for HBV immunotolerance and immunotherapy显示文摘一个适当小动物模型的缺乏仍然是一个主要障碍因为学习 immunotolerance 和 immunopathogenesis 由肝炎 B 病毒(HBV ) 导致了感染。在这研究,我们与 recombinant 在感染以后与持续 HBV viremia 报导一个老鼠模型带一个可复制的 HBV 染色体(AAV/HBV ) 的联系 adeno 的病毒(AAV ) 。类似于临床的 HBV 搬运人,感染 AAV/HBV 的老鼠为对 HBV 表面抗原(HBsAg ) 的抗体是 sero 否定的。有面对铝助手疫苗的常规 HBV 的免疫没能在这些老鼠对 HBV 得到有免疫力的回答。为了识别一支疫苗,那能潜在地围绕这忍耐, TLR9 收缩筋 CpG 作为一个助手被加到 HBsAg。有 HBsAg/CpG 的老鼠的种痘导致了 viremia,而且强壮的抗体生产和 T 房间回答的不仅清理。而且, DNA 复制和 HBV 的蛋白质表示显著地在 AAV/HBV-infected 鼠标的肝被减少。因此, AAV/HBV-infected 老鼠可以作为一个柔韧的模型被使用调查 HBV immunotolerance 并且为开发新奇免疫疗法根除的内在的机制 HBV 感染。 | Dan Yang Longchao Liu Danming Zhu Hua Peng Lishan Su Yang-Xin Fu Liguo Zhang | 2014 | Cellular & Molecular Immunology2014，11，1： | 25 |
| 5 | Variations of pore water sulfate gradients in sediments as indicator for underlying gas hydrate in Shenhu Area, the South China Sea显示文摘Shenhu Area is one of the most promising areas for gas hydrate exploration in the northern South China Sea (SCS). Pore water sulfate gradient, sulfate-methane interface (SMI) depth, and sulfate flux were analyzed at 53 sites in this area. SO42 gradient ranges between 0.33 and 4.43 mmol L-1 m-1 . SMI depths are from 7.7 to 87.9mbsf. Sulfate flux varies between 2.0 and 26.9 mmol m-2 yr-1 , with a mean of 11.7 mmol m-2 yr-1 . Correlation coefficient between SMI depth and methane flux for the 53 sites is 0.80, implying that methane flux regulates the rate of anaerobic methane oxidation (AMO), SMI depth, and sulfate flux. Twelve anomalous fields with high methane flux and steep sulfate gradients were recognized. Bottom simulating reflector (BSR) is distributed mainly in areas where SMI depth is less than 50 mbsf or places with sulfate flux larger than 3.5 mmol m-2 yr-1 . It is suggested that the Baiyun Sag and the Southern Uplift are potential areas for gas hydrate exploration. | WU LuShan YANG ShengXiong LIANG JinQiang SU Xin FU ShaoYing SHA ZhiBin YANG Tao | 2013 | Science China Earth Sciences2013，56，4： | 24 |
| 6 | Review on monolayer CBN superabrasive wheels for grinding metallic materials显示文摘A state-of-the-art review on monolayer electroplated and brazed cubic boron nitride(CBN) superabrasive wheels for grinding metallic materials has been provided in this article. The fabrication techniques and mechanisms of the monolayer CBN wheels are discussed. Grain distribution, wheel dressing, wear behavior, and wheel performance are analyzed in detail. Sample applications of monolayer CBN wheel for grinding steels, titanium alloys, and nickel-based superalloys are also provided. Finally, this article highlights opportunities for further investigation of monolayer CBN grinding wheels. | Ding Wenfeng Barbara Linke Zhu Yejun Li Zheng Fu Yucan Su Honghua Xu Jiuhua | 2017 | Chinese Journal of Aeronautics2017，30，1： | 24 |
| 7 | Autoantibody to MOG suggests two distinct clinical subtypes of NMOSD显示文摘We characterized a unique group of patients with neuromyelitis optica spectrum disorder(NMOSD) who carried autoantibodies of aquaporin-4(AQP4) and myelin-oligodendrocyte glycoprotein(MOG). Among the 125 NMOSD patients, 10(8.0%) were AQP4- and MOG-ab double positive, and 14(11.2%) were MOG-ab single positive. The double-positive patients had a multiphase disease course with a high annual relapse rate(P=0.0431), and severe residual disability(P<0.0001). Of the double-positive patients, 70% had MS-like brain lesions, more severe edematous, multifocal regions on spinal magnetic resonance imaging(MRI), pronounced decreases of retinal nerve fiber layer thickness and atrophy of optic nerves. In contrast, patients with only MOG-ab had a higher ratio of monophasic disease course and mild residual disability. Spinal cord MRI illustrated multifocal cord lesions with mild edema, and brain MRIs showed more lesions around lateral ventricles. NMOSD patients carrying both autoantibodies to AQP4 and MOG existed and exhibited combined features of prototypic NMO and relapsing-remitting form of MS, whereas NMOSD with antibodies to MOG only exhibited an 'intermediate' phenotype between NMOSD and MS. Our study suggests that antibodies against MOG might be pathogenic in NMOSD patients and that determination of anti-MOG antibodies maybe instructive for management of NMOSD patients. | Yaping Yan Yujing Li Ying Fu Li Yang Lei Su Kaibin Shi Minshu Li Qiang Liu Aimee Borazanci Yaou Liu Yong He Jeffrey L Bennett Timothy L Vollmer Fu-Dong Shi | 2016 | Science China(Life Sciences)2016，59，12： | 20 |
| 8 | Contemporary crustal tectonic movement in the southern Sichuan-Yunnan block based on dense GPS observation data显示文摘We analyzed 360 permanent and campaign GPS data from 1999 to 2017 in the southern Sichuan-Yunan block, and obtained crustal horizontal deformation in this region.Then, we derived the strain rate using a multi-scale spherical wavelet method.Results reveal a complex pattern of tectonic movement in the southern Sichuan-Yunnan block.Compared to the stable Eurasian plate, the maximum rate of the horizontal deformation in the southern Sichuan-Yunnan block is approximately 22 mm/a.The Xiaojiang fault shows a significantly lower deformation—a left-lateral strike-slip movement of 9.5 mm/a.The Honghe fault clearly shows a complex segmental deformation from the north to south.The northern Honghe fault shows 4.3 mm/a right strike-slip with 6.7 mm/a extension; the southern Honghe fault shows 1.9 mm/a right strike-slip with 1.9 mm/a extension; the junction zone in the Honghe and Lijiang–Xiaojinhe faults shows an obvious clockwise-rotation deformation.The strain calculation results reveal that the maximum shear-strain rate in this region reaches 70 nstrain/a, concentrated around the Xiaojiang fault and at the junction of the Honghe and Lijiang–Xiaojinhe faults.We note that most of the earthquakes with magnitudes of 4 and above that occurred in this region were within the high shear strain-rate zones and the strain rate gradient boundary zone, which indicates that the magnitude of strain accumulation is closely related to the seismic activities.Comparison of the fast shear-wave polarization direction of the upper-crust with the upper-mantle anisotropy and the direction of the surface principal compressive strain rate obtained from the inversion of the GPS data reveals that the direction of the surface principal compressive strain is basically consistent with the fast shear-wave polarization direction of the upper crust anisotropy, but different from the polarization direction of the upper mantle.Our results support the hypothesis that the principal elements of the deformation mechanism in the southern Sichuan-Yunnan block are decoupling between the upper and lower crust and ductile flow in the lower crust. | HongLin Jin Yuan Gao XiaoNing Su GuangYu Fu | 2019 | Earth and Planetary Physics2019，3，1： | 18 |
| 9 | Land Use Change and Anthropogenic Driving Forces:A Case Study in Yanhe River Basin显示文摘Human activities alter land use patterns and affect landscape sustainability. It is therefore very important to investigate the relationship between land use change and human activities. This study focuses on the detection of changing land use patterns in the Yanhe River Basin in northern Loess Plateau of China between 1995 and 2008. Landscape metrics were used to analyze the changing land use patterns and to explore the related anthropogenic driving forces. Results show that:1) Totally, 186 590 ha of croplands were converted into alternate land-use types (equivalent to 61.7% of the original cropland area). The majority of cropland areas were found to be converted into grassland and woodland areas (accounting for 55.9% and 4.9% respectively of the original cropland areas). 2) Both cropland and woodland demonstrated an increasing fragmentation tendency while grasslands showed a decreasing fragmentation tendency. 3) Multiple driving forces of land use change were thought to act together to changes in landscape metrics in the Yanhe River Basin. The anthropogenic driving forces were analyzed from four perspectives:ecological conservation policy, labor force transfer, industrial development, and rural settlement. The policy of the GfG (Grain for Green) project was the main driving factor which expedited the conversion from cropland to woodland and grassland. Industrial development was also found to affect land use change through the direct impact of economic activities such as oil exploration and agricultural production, or through indirect impacts such as the industrial structures readjustment. Labor force transfer from rural to urban areas was found to follow the industrial structure readjustment and further drove land use change from cropland to off-farm land use. Establishment of new tile-roofed houses instead of cave-type dwellings in rural settlements has helped to aggregate the original scattered land-use type of construction. | SU Changhong FU Bojie LU Yihe LU Nan ZENG Yuan HE Anna Halina LAMPARSKI | 2011 | Chinese Geographical Science2011，21，5： | 18 |
| 10 | Simvastatin inhibits apoptosis of endothelial cells induced by sepsis through upregulating the expression of Bcl-2 and downregulating Bax显示文摘BACKGROUND: Many studies have showed that apoptosis of endothelial cells plays a curial role in the progress of sepsis. But the role of simvastatin in apoptosis of endothelial cells induced by sepsis is not clear. The present study aimed to investigate the role of simvastatin in apoptosis of endothelial cells induced by sepsis and its mechanism.METHODS: Human umbilical vein endothelial cells(HUVECs) were randomly divided into three groups: control group, sepsis serum intervention group(sepsis group) and simvastatin+sepsis serum intervention group(simvastatin group). After 24-hour incubation with corresponding culture medium, the relative growth rate of HUVECS in different groups was detected by MTT assay; the apoptosis of HUVECs was detected by Hoechst33258 assay and fl ow cytometry; and the expression of the Bcl-2 and Bax genes of HUVECs was detected by PCR.RESULTS: Compared with the sepsis group, HUVECs in the simvastatin group had a higher relative growth rate. Apoptotic HUVECs decreased significantly in the simvastatin group in comparison with the sepsis group. Expression of the Bcl-2 gene in HUVECs decreased obviously, but the expression of the Bax gene increased obviously after 24-hour incubation with sepsis serum; however, the expression of the Bcl-2 and Bax genes was just the opposite in the simvastatin group.CONCLUSIONS: Our study suggests that simvastatin can inhibit apoptosis of endothelial cells induced by sepsis through upregulating the expression of Bcl-2 and downregulating Bax. It may be one of the mechanisms for simvastatin to treat sepsis. | Hui Fu Qiao-sheng Wang Qiong Luo Si Tan Hua Su Shi-lin Tang Zheng-liang Zhao Li-ping Huang | 2014 | World Journal of Emergency Medicine2014，5，4： | 18 |
| 11 | Microarray-Assisted Fine-Mapping of Quantitative Trait Loci for Cold Tolerance in Rice显示文摘包括冷压力抵抗,许多重要农学的特点由量的特点 loci (QTL ) 复杂、控制。这些 QTL 的隔离将极大地有益于农业工业,但是它是一项挑战性的任务。这研究由把 microarray 与印射 QTL 相结合以便在早幼苗的舞台从寒冷容忍的变化 IL112 识别寒冷容忍的 QTL 探索了综合策略。IL112 的所有早幼苗在 45 点为 9 d 通常幸存吗?? | Fengxia Liu Wenying Xu Qian Song Lubin Tan Jiayong Liu Zuofeng zhu Yongcai Fu Zhen Su Chuanqing Sun | 2013 | Molecular Plant2013，6，3： | 17 |
| 12 | Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients显示文摘 | ZHENG Ying CAI Guang-yan CHEN Xiang-mei FU Ping CHEN Jiang-hua DING Xiao-qiang YU Xue-qing LIN Hong-li LIU Jian XIE Ru-juan WANG Li-ning NI Zhao-hui LIU Fu-you YIN Ai-ping XING Chang-ying WANG Li SHI Wei LIU Jian-she HE Ya-ni DING Guo-hua LI Wen-ge WU Guang-li MIAO Li-ning CHEN Nan SU Zhen MEI Chang-lin ZHAO Jiu-yang GU Yong BAI Yun-kai LUO Hui-min LIN Shan CHEN Meng-hua GONG Li YANG Yi-bin YANG Xiao-ping LI Ying WAN Jian-xin WANG Nian-song LI Hai-ying XI Chun-sheng HAO Li XU Yan FANG Jing-ai LIU Bi-cheng LI Rong-shan WANG Rong ZHANG Jing-hong WANG Jian-qin LOU Tan-qi SHAO Feng-min MEI Feng LIU Zhi-hong YUAN Wei-jie SUN Shi-ren ZHANG Ling ZHOU Chun-hua CHEN Qin-kai JIA Shun-lian GONG Zhi-feng GUAN Guang-ju XIA Tian ZHONG Liang-bao | 2013 | Chinese Medical Journal2013，，12： | 16 |
| 13 | A Chromosome-Level Genome Assembly of Garlic (Allium sativum) Provides Insights into Genome Evolution and Allicin Biosynthesis显示文摘Garlic,an economically important vegetable,spice,and medicinal crop,produces highly enlarged bulbs and unique organosulfur compounds.Here,we report a chromosome-level genome assembly for garlic,with a total size of approximately 16.24 Gb,as well as the annotation of 57561 predicted protein-coding genes,making garlic the first Allium species with a sequenced genome.Analysis of this garlic genome assembly reveals a recent burst of transposable elements,explaining the substantial expansion of the garlic genome.We examined the evolution of certain genes associated with the biosynthesis of allicin and inulin neoseries-type fructans,and provided new insights into the biosynthesis of these two compounds.Furthermore,a large-scale transcriptome was produced to characterize the expression patterns of garlic genes in different tissues and at various growth stages of enlarged bulbs.The reference genome and large-scale transcriptome data generated in this study provide valuable new resources for research on garlic biology and breeding. | Xiudong Sun Siyuan Zhu Ningyang Li Yi Cheng Jing Zhao Xuguang Qiao Li Lu Shiqi Liu Yanzhou Wang Chan Liu Benping Li Wu Guo Shuang Gao Zemao Yang Fu Li Zheng Zeng Qing Tang Yupeng Pan Mengjiao Guan Jian Zhao Xiaomi ng Lu Huanwe n Meng Zhenlin Han Chun she ng Gao Wenkai Jiang Xing Zhao Shilin Tian Jianguang Su Zhihui Cheng Touming Liu | 2020 | Molecular Plant2020，13，9： | 14 |
| 14 | Kiwifruit recognition at nighttime using artificial lighting based on machine vision显示文摘Most researches involved so far in kiwifruit harvesting robot suggest the scenario of harvesting in daytime for taking advantage of sunlight.A robot operating at nighttime can overcome the problem of low work efficiency and would help to minimize fruit damage.In addition,artificial lights can be used to ensure constant illumination instead of the variable natural sunlight for image capturing.This paper aims to study the kiwifruit recognition at nighttime using artificial lighting based on machine vision.Firstly,an RGB camera was placed underneath the canopy so that clusters of kiwifruits could be included in the images.Next,the images were segmented using an R-G color model.Finally,a group of image processing conventional methods,such as Canny operator were applied to detect the fruits.The image processing results showed that this capturing method could reduce the background noise and overcome any target overlapping.The experimental results showed that the optimal artificial lighting ranged approximately between 30-50 lx.The developed algorithm detected 88.3%of the fruits successfully. | Fu Longsheng Wang Bin Cui Yongjie Su Shuai Yoshinori Gejima Taiichi Kobayashi | 2015 | International Journal of Agricultural and Biological Engineering2015，8，4： | 14 |
| 15 | Gas Sources of Natural Gas Hydrates in the Shenhu Drilling Area, South China Sea: Geochemical Evidence and Geological Analysis显示文摘The Shenhu gas hydrate drilling area is located in the central Baiyun sag, Zhu Ⅱ depression, Pearl River Mouth basin, northern South China Sea. The gas compositions contained in the hydrate-bearing zones is dominated by methane with content up to 99.89% and 99.91%. The carbon isotope of the methane (δ13C1 ) are 56.7‰ and 60.9‰, and its hydrogen isotope (δD) are 199‰ and 180‰, respectively, indicating the methane from the microbial reduction of CO2 . Based on the data of measured seafloor temperature and geothermal gradient, the gas formed hydrate reservoirs are from depths 24-1699 m below the seafloor, and main gas-generation zone is present at the depth interval of 416-1165 m. Gas-bearing zones include the Hanjiang Formation, Yuehai Formation, Wanshan Formation and Quaternary sediments. We infer that the microbial gas migrated laterally or vertically along faults (especially interlayer faults), slump structures, small-scale diapiric structures, regional sand beds and sedimentary boundaries to the hydrate stability zone, and formed natural gas hydrates in the upper Yuehai Formation and lower Wanshan Formation, probably with contribution of a little thermogenic gas from the deep sedments during this process. | ZHU Youhai HUANG Xia FU Shaoying SU Pibo | 2013 | Acta Geologica Sinica(English Edition)2013，87，3： | 13 |
| 16 | Effects of soil moisture and plant interactions on the soil microbial community structure显示文摘 | Chen MM Zhu YG Su YH Chen BD Fu BJ Marschner P | 2007 | 中国生物学文摘2007，21，6： | 13 |
| 17 | Jiao-tai-wan Up-regulates Hypothalamic and Peripheral Circadian Clock Gene Cryptochrome and Activates PI3K/AKT Signaling in Partially Sleep-deprived Rats显示文摘 | Wen-ya HUANG Xin ZOU Fu-er LU Hao SU Chu ZHANG Yan-lin REN Ke FANG Li-jun XU Kai- fu WANG Qing-jie CHEN Hui DONG | 2018 | Current Medical Science2018，38，4： | 13 |
| 18 | Comparisons in finite element analysis of minimally invasive, locking,and non-locking plates systems used in treating calcaneal fractures of Sanders type Ⅱ and type Ⅲ显示文摘 | He Kai Fu Su Liu Song Wang Zhifa Jin Dan | 2014 | Chinese Medical Journal2014，，22： | 13 |
| 19 | Curative effect of acupuncture on quality of life in patient with depression: a clinical randomized single-blind placebo-controlled study显示文摘OBJECTIVE:To evaluate the effect of acupuncture on the quality of life in patients with depression by clinical randomized single-blind placebo-controlled study.METHODS:one hundred and sixty-three cases of depression according with the inclusion criteria were randomly divided into a group of acupuncture dredging liver and regulating flow of theosophy(group 1),a group of acupoint shallow stab(group 2)and a group of non-acupoint shallow stab(group 3)at 1∶1∶1 ratio,and treated with acu-puncture,moxibustion,and intradermal embedding of needle,twice a week,for a total of 12 weeks.Scale of Quality of Life(SF-36)was used to measure the scores at four different time points and evaluate the effect of acupuncture on the quality of life of the patients with depression.RESULTS:At each time point after treatment,in scores of the 8 items,physical function,physical role,bodily pain,general physical condition,energy,social function,emotional function and mental health there were statistically significant differences among the 3 groups(P<0.0125).CONCLUSION:Acupuncture can effectively improve the quality of life of patients with depression. | Fan Ling Fu Wenbin Chen Zhao Xu Nenggui Liu Jianhua LǚAiping Li Ziping Su Shengyong Wu Taixiang Ou Aihua | 2016 | Journal of Traditional Chinese Medicine2016，36，2： | 12 |
| 20 | Sequencing of p53 mutation in established human hepatocellular carcinoma cell line of HHC4 and HHC15 in nude mice显示文摘INTRODUCTIONAlthoughtheetiopathologyofhumanhepatocelularcarcinoma(hHCC)isstilunknown,alotofevidencestronglysuggestedthatinfec... | YANG Shan Min, ZHOU Hong, CHEN Rui Chuan, WANG Yu Fang, CHEN Fu, ZHANG Chang Gong, ZHEN Yun, YAN Jiang Hua and SU Jin Hua | 1998 | World Journal of Gastroenterology1998，4，6： | 11 |
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