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| 1 | Ultrasound-assessed non-culprit and culprit coronary vessels differ by age and gender显示文摘AIM: To investigate age-and gender-related differences in non-culprit versus culprit coronary vessels assessed with virtual histology intravascular ultrasound (VH-IVUS). METHODS: In 390 patients referred for coronary angiography to a single center (Luzerner Kantonsspital, Switzerland) between May 2007 and January 2011, 691 proximal vessel segments in left anterior descending, circumflex and/or right coronary arteries were imaged by VH-IVUS. Plaque burden and plaque composition(fibrous, fibro-fatty, necrotic core and dense calcium volumes) were analyzed in 3 age tertiles, according to gender and separated for vessels containing non-culprit or culprit lesions. To classify as vessel containing a culprit lesion, the patient had to present with an acute coronary syndrome, and the VH-IVUS had to be performed in a vessel segment containing the culprit lesion according to conventional coronary angiography. RESULTS: In non-culprit vessels the plaque burden increased significantly with aging (in men from 37% ± 12% in the lowest to 46% ± 10% in the highest age tertile, P < 0.001; in women from 30% ± 9% to 40% ± 11%, P < 0.001); men had higher plaque burden than women at any age (P < 0.001 for each of the 3 age tertiles). In culprit vessels of the lowest age tertile, plaque burden was significantly higher than that in non- culprit vessels (in men 48% ± 6%, P < 0.001 as compared to non-culprit vessels; in women 44% ± 18%, P = 0.004 as compared to non-culprit vessels). Plaque burden of culprit vessels did not significantly change during aging (plaque burden in men of the highest age tertile 51% ± 9%, P = 0.523 as compared to lowest age tertile; in women of the highest age tertile 49% ± 8%, P = 0.449 as compared to lowest age tertile). In men, plaque morphology of culprit vessels became increasingly rupture-prone during aging (increasing percentages of necrotic core and dense calcium), whereas plaque morphology in non-culprit vessels was less rupture-prone and remained constant during aging. In women, necrotic core in non-culprit vessels was very low at young age, but increased during aging resulting in a plaque morphology that was very similar to men. Plaque morphology in culprit vessels of young women and men was similar. CONCLUSION: This study provides evidence that age-and gender-related differences in plaque burden and plaque composition significantly depend on whether the vessel contained a non-culprit or culprit lesion. | Andreas W Schoenenberger Nadja Urbanek Stefan Toggweiler Andreas E Stuck Thérèse J Resink Paul Erne | 2013 | World Journal of Cardiology2013，5，3： | 7 |
| 2 | A striking local esophageal cytokine expression profile in eosinophilic esophagitis显示文摘 | Carine Blanchard Emily M. Stucke Beatriz Rodriguez-Jimenez Karen Burwinkel Margaret H. Collins Annette Ahrens Eileen S. Alexander Bridget K. Buckmeier Butz Sean C. Jameson Ajay Kaul James P. Franciosi Jonathan P. Kushner Philip E. Putnam J. Pablo Abonia M | 2010 | The Journal of Allergy and Clinical Immunology2010，，1： | 3 |
| 3 | Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin Ⅱ are prevented by AMP-activated protein kinase 显示文摘 | Stuck B J Lenski M Bfhm M | 2008 | J Biol Chem2008，283，32： | 1 |
| 4 | Preven-ting disability in elderly people 显示文摘 | Stuck AE Beck JC Egger M | 2004 | Lancet2004，364，9446： | 1 |
| 5 | Volumetric tissre reduction in radiofrequeney Surgery of the tongue 显示文摘 | Stuck B A Kopke J Hormann K | 2005 | Otolaryngol head neck surg2005，123，： | 1 |
| 6 | Am 1 a price-fixer? a behavioral economics analysis of Cartels显示文摘 | MAURICE E STUCKE | 2010 | University of Tennessee Legal Studies Research Paper2010，97，： | 1 |
| 7 | Minimum error dispersion linear filtering of scalar symmetric stable processes显示文摘 | STUCK B W | 1978 | IEEE Transaction Automatic Control1978，23，3： | 1 |
| 8 | Concomitant administration of varicella vaccine with combined measles,mumps and rubella vaccine in healthy children aged 12 to 24 months of age显示文摘 | Stuck B Stehr K Bock HL | | 0，，02： | 1 |
| 9 | Ego depletion and aggressive behavior: Is the inhibition of aggression a limited resource? 显示文摘 | Stucke T S Baumeister R F | 2006 | European Journal of Social Psychology2006，，： | 1 |
| 10 | Rituximab added to first - line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma:an East German Study Group Hematology and Oncology Study显示文摘 | Herald M Haas A Stuck S | 2007 | J Clio Oncol2007，25，15： | 1 |
| 11 | Com- plications of tempera 2ture - cont rolled radiof re- quency volumet ric tissue reduction forsleep - disorder-ed breat hing显示文摘 | Stuck B A Starzak K Verse T | 2003 | Acta Otolaryngol2003，123，4： | 1 |
| 12 | Metabolic switch and hy-pertrophy of cardiomyocytes following treatment with angiotensinⅡare prevented by AMP-activated protein kinase显示文摘 | Stuck BJ Lenski M B?hm M | 2008 | J Biol Chem2008，283，32： | 1 |
| 13 | Farm-level studies of particulate phosphorus transport in the Everglades Agricultural Area 显示文摘 | STUCK J D LZUNO E T CAMPBELL K L | 2001 | Transactions of the American Society of Agncultural Engineers2001，44，： | 1 |
| 14 | Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis 显示文摘 | Blanchard C Stucke EM Burwinkel K ct al | 2010 | J Immunol2010，184，7： | 1 |
| 15 | Comparison of popula- tion genetic diversity between a rare, narrowly distributed species and a common, widespread species of Alnu ( Betu- laeeae) 显示文摘 | Gibson J P Rice S A Stucke C M | 2008 | Am J Bot2008，95，： | 1 |
| 16 | Comparison of popula- tion genetic diversity between a rare, narrowly distributed species and a common,widespread species of Alnus (Betu- laceae) 显示文摘 | Gibson J P Rice S A Stucke C M | 2008 | Am J Bot2008，95，： | 1 |
| 17 | Fleroxacin clinical pharmacokinetics显示文摘 | Stuck A E Kim D K Frey F J | 1992 | Clin Pharmacokinet1992，22，： | 1 |
| 18 | Effects of sevoflurane on excitatory neurotrans- mission to medullary expiratory neurons and on phrenic nerve activity in a decerebrate dog model显示文摘 | STUCKE A G STUTH E A TONKOVIC-CAPIN V | 2001 | Anesthesiology2001，95，2： | 1 |
| 19 | Another possible mechanism for bronchospasm after rapacuronium显示文摘 | STUTH EA STUCKE AG SETLOCK MA | 2002 | Anesthesiology2002，96，6： | 1 |
| 20 | Palatal implants for primary snoring:short-term results of a new minimally invasive surgical technique显示文摘 | Maurer JT Verse T Stuck BA | 2005 | Otolaryngol Head Neck Surg2005，132，： | 1 |
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