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| 1 | MRI-determined fat content of human liver,pancreas and kidney显示文摘AIM:To assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body weight.METHODS:Magnetic resonance spectroscopy and a previously validated gradient echo magnetic resonance imaging method with Dixon's two point technique were used in this study to quantify fat in liver,pancreas as well as kidney.RESULTS:In 36 volunteers with body mass index(BMI) ranging from 20.0 to 42.9 kg/m2,the median fat content of liver,pancreas and kidney was 2.3%(interquartile range:0.2%-7.8%),2.7%(1.0%-6.5%) and 0.7%(0.1%-1.4%),respectively.BMI and subcutaneous fat correlated significantly with liver and pancreas fat content.We show for the first time the significant correlation of liver and pancreas fat content in healthy controls(r = 0.43,P < 0.01).These observations are related to body weight as measured by BMI and the amount of subcutaneous fat.Kidney fat content is very low and correlates with none of the other fat depots.CONCLUSION:Renal lipid accumulation,unlike the coupled accumulations of fat in liver and pancreas,is not observed in obese subjects.Unlike suggestions made in previous studies,renal lipid accumulation appears not to be involved in the pathogenesis of renal disease in humans. | Paul E Sijens Mireille A Edens Stephan JL Bakker Ronald P Stolk | 2010 | World Journal of Gastroenterology2010,16,16: | 14 |
| 2 | 两种新型骨水泥的组织学和生物力学研究显示文摘我们研制了两种可被骨长入的骨水泥:一种是部分可吸收的骨水泥(PRC),以双酚α-甲基丙烯酸甘油酯(Bis-GMA)为基质,混合硅铝陶瓷和可吸收性聚合体颗粒调制成;另一种是磷酸钙骨水泥(CPC),由磷酸三钙、一水磷酸二氢钙、二水磷酸二钙和黄原胶组成。将这两种骨水泥分别植入家兔股骨和胫骨髁的骨缺损中,植入后2、4、12和24周取材,进行组织学观察和生物力学测试。结果发现,CPC组有递增的骨整合,伴有生物降解及巨噬细胞出现,力学测试显示抗压强度在4周之前一直降低,4周后才轻微升高,弹性模量随时间普遍降低。到第4周时,组织学观察还发现新生骨与CPC边缘直接接触。整个观察过程中未发现炎症反应。PRC组,骨整合及生物降解都很轻微,但在各个观察阶段,其抗压强度比松质骨和CPC组高(p<0.05),在4周之前,它的弹性模量高于松质骨和CPC组,4周后低于松质骨。(Bone 25:41S--45S;1999)。 | 卢建熙 I ABOUT G STEPHAN P VAN LANDUYT J DEJOU M FIOCCHI J LEMAITRE J-P PROUST | 2000 | 医用生物力学2000,15,3: | 10 |
| 3 | Clinical End Points in Coronary Stent Trials: A Case for Standardized Definitions显示文摘 | Donald E. Cutlip Stephan Windecker Roxana Mehran Ashley Boam David J. Cohen Gerrit-Anne van Es P Gabriel Steg Marie-angèle Morel Laura Mauri Pascal Vranckx Eugene McFadden Alexandra Lansky Martial Hamon Mitchell W. Krucoff Patrick W. Serruys | 2007 | Circulation2007,,17: | 4 |
| 4 | Aligned carbon nanotube arrays formed by cutting a polymer resin-nanotube composite显示文摘 | Ajayan P M Stephan O Colliex C | 1994 | Science1994,265,16: | 2 |
| 5 | Distal femoral fractures显示文摘 | Schandelmaier P Stephan C Krettek C | 2000 | Unfallchirurg2000,103,6: | 1 |
| 6 | Aligned carbon nanotube arrays formed by cutting a polymer resin-nanotube composite显示文摘 | AJAYAN P M STEPHAN O COLLIEX C | 1994 | Science1994,265,: | 1 |
| 7 | Aligned carbon nanotube arrays formed by cutting a polymer resin-nanotube composite显示文摘 | STEPHAN O COLLIEX C | 1994 | Science1994,265,: | 1 |
| 8 | The use of Poller sc'rews as blocking screws in stabilising tibial frac- tures treated with small diameter intramedullary nails 显示文摘 | Krettek C Stephan C Schandelmaier P | 1999 | J Bone Joint Surg Br1999,81,6: | 1 |
| 9 | 显示文摘 | Ajayan P M Stephan D Redlich P H | 1993 | Nature1993,361,: | 1 |
| 10 | Effect of supplementing head-down displays with 3-Daudio during visual target acquisition显示文摘 | PARKER S P A SIMITH S E STEPHAN K L | 2004 | InternationalJournal of aviation psychology2004,14,3: | 1 |
| 11 | 2014 ESC/EACTS guidelines on myocardial revascularization显示文摘 | Stephan W Kolh P Alfonso F | 2015 | Rev Esp Cardiol(Engl Ed)2015,68,2: | 1 |
| 12 | Wavelet compression of four-dimensional arbitrarily size echocardiographic data显示文摘 | LI Zeng Jansen P Christian Marsch Stephan | 2002 | IEEE Trans on Medical Imaging2002,21,9: | 1 |
| 13 | The use of Poller screws as blocking screws in stabilizing tibial frac-tures treated with small diameter intrarnedullary nails显示文摘 | Krettek C Stephan C Schandelmaier P | 1999 | J Bone Joint Surg (Br)1999,81,6: | 1 |
| 14 | Aligned carbon nanotube arrays for med by cutting a polymer resin - nanotube composite 显示文摘 | Ajayan P M Stephan O Col lexC | 1994 | Science1994,265,5176: | 1 |
| 15 | Enforced expression of EBF in hematopoietic stem cells restricts lymphopoiesis to the B cell lineage显示文摘 | Zheng Z Claudiu V C Robert P Stephan | 2003 | EMBO J2003,22,: | 1 |
| 16 | Analysis of the heat transfer coefficient of grooved heat pipe evaporator walls显示文摘 | STEPHAN P C BUSSE C A | 1992 | Int J Heat Mass Transfer1992,35,2: | 1 |
| 17 | High-flow nasal oxygen vs noninvasive positive airway pressure in hypox- emic patients after cardiothoracic surgery: a randomized clinical Trial显示文摘 | Stephan F Barrucand B Petit P | 2015 | JAMA2015,313,23: | 1 |
| 18 | Design and Optimization of Three-dimesional Extrusion Dies Using Constraint Optimization Algorithm显示文摘 | Nadhir L Fahriee S Stephan P | 2009 | Analysis and Design2009,45,: | 1 |
| 19 | 显示文摘 | Ajayan P M Stephan D Redlich P H | 1995 | Nature1995,375,: | 1 |
| 20 | Selenium and Tellurium Systematics of the Earth's Mantle from High Precision Analyses of Ultra-Depleted Orogenic Peridotites显示文摘 | Stephan K Ambre L Jean P L | 2012 | Geochimical et Cosmochimica Acta2012,86,: | 1 |