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| 1 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 2 | The role of diagnostic radiology in compressive and entrapment neuropathies显示文摘 | Spratt JD Stanley A J Grainger A J | 2008 | Eur Radiol2008，12，： | 1 |
| 3 | Spinal pedicle fixation: reliability and validity of roentgenogram-based assessment and surgical factors on successful screw placement 显示文摘 | Weinstein J N Spratt K F Spengler D | 1988 | Spine1988，13，9： | 1 |
| 4 | Modeling shifts in microbial populations associated with health or disease显示文摘 | Dalwai F Spratt DA Pratten J | 2006 | Appl Environ Microbiol2006，72，5： | 1 |
| 5 | An in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates显示文摘 | Spratt DA Pratten J Wilson M | 2001 | Inter End J2001，34，： | 1 |
| 6 | Modeling shifts in microbial populations associated with health or disease 显示文摘 | DALWAI F SPRATT DA PRATTEN J | 2006 | Appl Environ Microbiol2006，72，5： | 1 |
| 7 | Thoracolumbar burst fracturces:The Clinical efficacy and outcome of nouoperative management显示文摘 | Mumford J Wein stein JN Spratt KF | 1993 | Spine1993，18，： | 1 |
| 8 | Sulfate reduction in peat from a New Jersey Pinelands cedar swamp 显示文摘 | Henry G Spratt J Morgan M D | 1987 | Appl Environ Microbiol1987，53，7： | 1 |
| 9 | Impact of FDG PE- T/CT on delineation of the gross tumor volume for radiation planning in non-small-cell lung cancer显示文摘 | Spratt DE Diaz R McElmurray J | 2010 | Clin Nucl Med2010，35，4： | 1 |
| 10 | Clinical defiv erysystem for intraperitoneal hyeahemie chemotherapy 显示文摘 | Spratt J S Adcoek R A Muxeovin M | 1980 | Cancer Res1980，40，2： | 1 |
| 11 | Studies on semen collection in waterfowl by electrical stimulations显示文摘 | Samour H J Spratt D M J Hutton R E | 1985 | British Veterinary Journal1985，141，： | 1 |
| 12 | Spinal pedicle fixation:reliability and validity of roentgenogram-based assessment and surgical factors on successful screw placement 显示文摘 | WEINSTEIN J N SPRATT K F SPENGLER D | 1988 | Spine1988，13，： | 1 |
| 13 | 显示文摘 | Zorinsky E J Spratt D B Virkus R L | 1986 | J IEDM1986，86，： | 1 |
| 14 | Lumbar discography in normal subjects:a controlled prospective study显示文摘 | Walsh T Werstein J Spratt K | 1990 | J Bone Joint Surg(Am)1990，72，7： | 1 |
| 15 | Crustal rheology of the Himalaya and Southern Tibet inferred from magnetotelluric data显示文摘 | Unsworth M J Jones A G Wei W Marquis G Gokarn S G Spratt J E and the INDEPTH-MT team | 2005 | Nature2005，438，7064： | 1 |
| 16 | Plaque stabilisation by systemic and local drug administration显示文摘 | Spratt J C Eamenzined E | 2004 | Heart2004，90，12： | 1 |
| 17 | Grion dissection显示文摘 | Spratt J | 2000 | J Surg Oncol2000，73，4： | 1 |
| 18 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 19 | Effi- cacy of flexion and extension treatments incorporating braces for low-back pain patients with retrodisplacement, spondylolisthe- sis, or normal sagittal translation显示文摘 | SPRATT K F WEINSTEIN J N LEHMANN T R et aI | 1993 | Spine1993，18，13： | 1 |
| 20 | Hip fracture outcome:is there a 'July effect'显示文摘 | ANDERSON K L KOVAL K J SPRATT K F | 2009 | Am Orthop(Belle Mead NJ)2009，38，12： | 1 |
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