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| 1 | Review on Stress Corrosion and Corrosion Fatigue Failure of Centrifugal Compressor Impeller显示文摘Corrosion failure,especially stress corrosion cracking and corrosion fatigue,is the main cause of centrifugal compressor impeller failure.And it is concealed and destructive.This paper summarizes the main theories of stress corrosion cracking and corrosion fatigue and its latest developments,and it also points out that existing stress corrosion cracking theories can be reduced to the anodic dissolution(AD),the hydrogen-induced cracking(HIC),and the combined AD and HIC mechanisms.The corrosion behavior and the mechanism of corrosion fatigue in the crack propagation stage are similar to stress corrosion cracking.The effects of stress ratio,loading frequency,and corrosive medium on the corrosion fatigue crack propagation rate are analyzed and summarized.The corrosion behavior and the mechanism of stress corrosion cracking and corrosion fatigue in corrosive environments,which contain sulfide,chlorides,and carbonate,are analyzed.The working environments of the centrifugal compressor impeller show the behavior and the mechanism of stress corrosion cracking and corrosion fatigue in different corrosive environments.The current research methods for centrifugal compressor impeller corrosion failure are analyzed.Physical analysis,numerical simulation,and the fluid-structure interaction method play an increasingly important role in the research on impeller deformation and stress distribution caused by the joint action of aerodynamic load and centrifugal load. | SUN Jiao CHEN Songying QU Yanpeng LI Jianfeng | 2015 | Chinese Journal of Mechanical Engineering2015，28，2： | 14 |
| 2 | Effects of Temperature and Pressure on Stress Corrosion Cracking Behavior of 310S Stainless Steel in Chloride Solution显示文摘310S is an austenitic stainless steel for high temperature applications, having strong resistance of oxidation, hydrogen embrittlement and corrosion. Stress corrosion cracking(SCC) is the main corrosion failure mode for 310 S stainless steel. Past researched about SCC of 310 S primarily focus on the corrosion mechanism and influence of temperature and corrosive media, but few studies concern the combined influence of temperature, pressure and chloride. For a better understanding of temperature and pressure's effects on SCC of 310 S stainless steel, prepared samples are investigated via slow strain rate tensile test(SSRT) in different temperature and pressure in NACE A solution. The result shows that the SCC sensibility indexes of 310 S stainless steel increase with the rise of temperature and reach maximum at 10 MPa and 160℃, increasing by 22.3% compared with that at 10 MPa and 80 ℃. Instead, the sensibility decreases with the pressure up. Besides, the fractures begin to transform from the ductile fracture to the brittle fracture with the increase of temperature. 310 S stainless steel has an obvious tendency of stress corrosion at 10 MPa and 160℃ and the fracture surface exists cleavage steps, river patterns and some local secondary cracks, having obvious brittle fracture characteristics. The SCC cracks initiate from inclusions and tiny pits in the matrix and propagate into the matrix along the cross section gradually until rupture. In particular, the oxygen and chloride play an important role on the SCC of 310 S stainless steel in NACE A solution. The chloride damages passivating film, causing pitting corrosion, concentrating in the cracks and accelerated SSC ultimately. The research reveals the combined influence of temperature, pressure and chloride on the SCC of 310 S, which can be a guide to the application of 310 S stainless steel in super-heater tube. | ZHONG Yunpan ZHOU Cheng CHEN Songying WANG Ruiyan | 2017 | Chinese Journal of Mechanical Engineering2017，30，1： | 9 |
| 3 | How do Chinese medicines that tonify the kidney inhibit dopaminergic neuron apoptosis?显示文摘Wistar rats were intragastrically perfused with Chinese medicines used for tonifying the kidney.These included 0.180 g/mL of Herba Epimedii(Epimedium), Semen Cuscutae(Dodder Seed), or Herba Cistanches(Desertliving Cistanche), 0.04 mg/mL monoamine oxidase-B inhibitor selegiline,or distilled water for 14 consecutive days to prepare drug-containing serum or blank serum.MES23.5 cells in the logarithmic phase were cultured in media supplemented with 15%drug-containing serum for 24 hours, followed by incubation in culture solution containing 100 μmol/L H2O2for 3 hours. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) and flow cytometry results showed that all drug-containing serums improved the survival rate of H2O2-injured MES23.5 cells, inhibited pro-apoptotic FasL and caspase-3 expression, promoted anti-apoptotic Bcl-2 expression. However, drug-containing serums had little influence on Fas expression in H2O2-injured MES23.5 cells. Enzyme-linked immunosorbent assay results showed that serum containing Herba Cistanches or Herba Epimedii increased the expression of nerve growth factor,brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in injured MES23.5cells; serum containing Semen Cuscutae only increased brain-derived neurotrophic factor expression; while expression of the above neurotrophic factors remained the same in cells treated with serum containing selegiline. These findings indicate that Chinese medicines used to tonify the kidney can protect nerve cells by regulating the expression of apoptosis-related factors and neurotrophic factors in MES23.5 cells. | Shaogang Lin Shuifen Ye Jinmu Huang Yun Tian Yihui Xu Mengqi Wu Jingxia Wang Songying Wu Jing Cai | 2013 | Neural Regeneration Research2013，8，30： | 9 |
| 4 | Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway显示文摘Whether and how garlic-derived S-allylmercaptocysteine(SAMC) inhibits hepatocellular carcinoma(HCC) is largely unknown. In the current study, the role of low-density lipoprotein receptor(LDLR)-related protein 6(LRP6) in HCC progression and the anti-HCC mechanism of SAMC was examined in clinical sample, cell model and xenograft/orthotopic mouse models. We demonstrated that SAMC inhibited cell proliferation and tumorigenesis, while induced apoptosis of human HCC cells without influencing normal hepatocytes. SAMC directly interacted with Wnt-pathway co-receptor LRP6 on the cell membrane. LRP6 was frequently over-expressed in the tumor tissue of human HCC patients(66.7% of 48 patients) and its overexpression only correlated with the over-expression of β-catenin, but not with age, gender, tumor size, stage and metastasis. Deficiency or over-expression of LRP6 in hepatoma cells could partly mimic or counteract the anti-tumor properties of SAMC, respectively. In vivo administration of SAMC significantly suppressed the growth of Huh-7 xenograft/orthotopic HCC tumor without causing undesirable side effects. In addition, stable down-regulation of LRP6 in Huh-7 facilitated the anti-HCC effects of SAMC. In conclusion, LRP6 can be a potential therapeutic target of HCC. SAMC is a promising specific anti-tumor agent for treating HCC subtypes with Wnt activation at the hepatoma cell surface. | Jia Xiao Feiyue Xing Yingxia Liu Yi Lv Xiaogang Wang Ming-Tat Ling Hao Gao Songying Ouyang Min Yang Jiang Zhu Yu Xia Kwok-Fai So George L.Tipoe | 2018 | Acta Pharmaceutica Sinica B2018，8，4： | 6 |
| 5 | The emerging roles of the DDX41 protein in immunity and diseases显示文摘RNA helicases 涉及几乎 RNA 的每个方面,从抄写到 RNA 腐烂。DExD/H-box helicases 包括最大的 SF2 helicase 总科,它被二个保存象 RecA 一样领域描绘。在最近的年里,这些蛋白质的越来越多的意外功能被发现了。他们不仅在天生的有免疫力的反应而且在象癌症和长期的丙肝一样的疾病起重要作用。在这评论,我们在 SF2 总科的一个成员上总结最近的文学,死了盒子的蛋白质 DDX41。在细菌或病毒的感染以后, DNA 或 cyclic-di-GMP 被释放到房间。在由 BTK kinase 的 Tyr414 的 phosphorylation 以后, DDX41 将充当一个传感器认出侵略者,由类型的正式就职列在后面我干扰素(IFN ) 。在有免疫力的反应以后, DDX41 被 E3 ligase TRIM21 降级,用象 ubiquitination 地点的 DDX41 的 Lys9 和 Lys115。除在天生的免疫的角色以外, DDX41 也与疾病有关。越来越多的在 DDX41 继承了并且获得变化基因从 myelodysplastic 症候群或尖锐 myeloid 白血病(MDS/AML ) 被识别病人。评论在果蝇集中于 DDX41,以及它的相当或相同的事物 Abstrakt,它是重要的因为幸存根本全部上演苍蝇的生命周期。 | Yan Jiang Yanping Zhu Zhi-Jie Liu Songying Ouyang | 2017 | Protein & Cell2017，8，2： | 6 |
| 6 | Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage显示文摘Asparaginyl endopeptidase (AEP ) 是有为在 P1 地点的天门冬素残余的偏爱的 endo/lysosomal 半胱氨酸 endopeptidase 并且在像使用费的受体 3/7/9 的成熟起一个重要作用。AEP 被知道为催化激活在酸的 pH 经历 autoproteolytic 成熟。这里,我们描述 AEP 酶原的水晶结构和 AEP 的成熟形式。在 AEP 和 caspases 之间的结构的比较在关键残余的作文并且在催化机制揭示了类似。Mutagenesis 研究作为为肽底层的劈开是必要的残余识别了 N44, R46, H150, E189, C191, S217/S218 和 D233。在成熟期间, AEP 的帽子领域的 autoproteolytic 劈开在核心领域上开创存取到活跃地点。出人意料地,一个中间的 autoproteolytic 成熟阶段被发现在近似 pH 4.5 在哪个部分激活的 AEP 能被颠倒回到它的酶原形式。这个唯一的特征被 AEP pH4.5 (AEP 在 pH 被成熟 4.5 并且在 pH 结晶 8.5 ) ,在哪个破肽契约被重新绑扎,结构被转变回到它的酶原形式。另外, AEP 禁止者 cystatin C 能被充分激活的 AEP 消化,但是不能被激活的组织蛋白酶消化。因此,我们第一次证明 cystatins 可以为活跃地点通过底层竞争调整 AEP 的活动。 | Lixia Zhao Tian Hua Christopher Crowley Heng Ru Xiangmin Ni Neil Shaw Lianying Jiao Wei Ding Lu Qu Li-Wei Hung Wei Huang Lei Liu Keqiang Ye Songying Ouyang Genhong Cheng Zhi-Jie Liu | 2014 | Cell Research2014，24，3： | 6 |
| 7 | Structural insights into Cas13b-guided CRISPR RNA maturation and recognition显示文摘Dear Editor,CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins)systems are RNA-guided adaptive immune systems in prokaryotes.^1,2 Class 2 CRISPR-Cas systems (including type Ⅱ,Ⅴ,and Ⅵ)involve large single effector proteins in complex with crRNA for interference. | Bo Zhang Weiwei Ye Yangmiao Ye Huan Zhou Abdullah F.U.H.Saeed Jing Chen Jinying Lin Vanja Perculija Qi Chen Chun-Jung Chen Ming-Xian Chang Muhammad lqbal Choudhary Songying Ouyang | 2018 | Cell Research2018，28，12： | 5 |
| 8 | Genetic divergence of weedy rice populations associated with their geographic location and coexisting conspecific crop: Implications on adaptive evolution of agricultural weeds显示文摘蔓延的米饭,栽培米饭的一样的生物种类,是大批出没于世界范围的稻田的一棵有害杂草。在中国决定蔓延的米饭的基因差异,结构,和关系,我们使用了插入 / 删除(InDel ) 分析蔓延的米饭人口从的分子的指纹对作为参考书种区域,使用的装饰用的梨树和 indica 米饭栽培变种的南部的米饭东北。InDel 指纹显示了相对高的全面基因差异(H 为从 14 张蔓延的米饭人口的 240 件样品的 e = 0.42) 。然而,许多更低的在内人口差异被检测,特别地为从东北、南部的中国的人口,与 H e 价值从 0.006 ~ 0.06 。江苏人口显示出高得多的在内人口基因差异(H e = 0.12-0.31) 比那些从另外的区域。分子的变化和 F st 显示出 ∼88% 在蔓延的米饭人口之中的基因变化。主要部件和结构分析显示了实质的 japonica-indica 蔓延的米饭人口的基因区别。从江苏省的蔓延的米饭甚至在人口以内正在经历 indica 装饰用的梨树区别,它由于由在这个区域的装饰用的梨树米饭变化的 indica 的代替是可能的。在结论,重要基因分叉在中国发生在蔓延的米饭人口之中,它与他们的地理地点和共存的米饭变化被联系。从栽培米饭的基因渗入在在人影响的 agro 生态系统塑造蔓延的米饭人口的基因差异和结构有一个关键角色。 | Zhuo-Jun songI Zhe Wang Yang Feng Nan Yao Ji Yang Bao-Rong Lu | 2015 | Journal of Systematics and Evolution2015，53，4： | 5 |
| 9 | Mechanism of the Rpn13-induced activation of Uch37显示文摘 | Lianying Jiao Songying Ouyang Neil Shaw Gaojie Song Yingang Feng Fengfeng Niu Weicheng Qiu Hongtao Zhu Li-Wei Hung Xiaobing Zuo V. Eleonora Shtykova Ping Zhu Yu-Hui Dong Ruxiang Xu Zhi-Jie Liu | 2014 | Protein & Cell2014，5，8： | 4 |
| 10 | Fault Detection in Coal Seam by the Channel Wave Method显示文摘 | Wei Wang Xing Gao Songying Li Yong Le Jiwen Teng Yuying Li | 2014 | 地球科学期刊(中英文版)2014，4，1： | 2 |
| 11 | Prevention,diagnosis,and management of interstitial pregnancy:A review of the literature显示文摘Objective:The incidence of interstitial pregnancy(IP)has increased by using assisted reproductive technology,especially after ipsilateral salpingectomy.This review aimed to examine the current state of prevention,risk factors,diagnosis,and management of IP,based on the current literature.Data sources:We searched PubMed for English language articles published up to June 2018.The search terms included interstitial pregnancy,ectopic pregnancy or cornual pregnancy,angular pregnancy,and combinations of these terms.Study selection:Articles were obtained and reviewed to analyze risk factors,diagnosis,prevention,and management of IP.Results:Ipsilateral salpingectomy is the main high-risk factor of IP,especially after in vitro fertilization.Cornual suture at the time of salpingectomy helps to reduce the IP rate.Laparoscopic cornuostomy appears to be an effective treatment in intact cases,although it sometimes needs to be combined with methotrexate therapy in ruptured cases complicated by persistent disease. | Jianmin Chen Dong Huang Libing Shi Songying Zhang | 2019 | Laparoscopic, Endoscopic and Robotic Surgery2019，2，1： | 2 |
| 12 | A comparison of intrauterine balloon, intrauterine contraceptive device and hyaluronic acid gel in the prevention of adhesion reformation following hysteroscopic surgery for Asherman syndrome: a cohort study显示文摘 | Xiaona Lin Minling Wei T.C. Li Qiongxiao Huang Dong Huang Feng Zhou Songying Zhang | 2013 | European Journal of Obstetrics and Gynecology2013，，： | 2 |
| 13 | Chronic cornual ectopic pregnancy presenting as large cornual mass after in vitro fertilization-embryo transfer:A case report显示文摘Chronic cornual ectopic pregnancy is rare.A 37-year-old woman,G1P0,presented with cornual mass,mild vaginal bleeding,and low serum human chorionic gonadotropin.Cornuostomy and cornual repair were performed by laparoscopy.With atypical symptoms,chronic cornual ectopic pregnancy is a challenge for the gynecologists to make accurate diagnosis and effective treatment. | Cuiyu Yang Dong Huang Songying Zhang | 2019 | Laparoscopic, Endoscopic and Robotic Surgery2019，2，4： | 2 |
| 14 | Progress in pharmacological research of Platycodon grandiflorurm显示文摘 | SongY(宋杨) QiY(齐云) | 2006 | 中国药房2006，17，： | 1 |
| 15 | Cholesteryl ester transfer protein actitity and athergenic parameters in rabbits supplemented with cholesterol and garlic powder 显示文摘 | Kwon MJ SongYS Choi MS | 2003 | Life Sci2003，72，： | 1 |
| 16 | Thermoelectricpropertiesofgraphenenanosheets-modifiedpolyanilinehybridnanocompositesbyaninsituchemicalpolymeriztion显示文摘 | LuY SongY WangF | 2012 | MaterialsChemistryandPhysics2012，138，1： | 1 |
| 17 | Binding of bacterial secondary messenger molecule c di-GMP is a STING operation显示文摘Initial skirmishes between the host and pathogen result in spillage of the contents of the bacterial cell.Amongst the spillage,the secondary messenger molecule,cyclic dimeric guanosine monophosphate(c di-GMP),was recently shown to be bound by stimulator of interferon genes(STING).Binding of c di-GMP by STING activates the Tank Binding Kinase(TBK1)mediated signaling cascades that galvanize the body’s defenses for elimi-nation of the pathogen.In addition to c di-GMP,STING has also been shown to function in innate immune re-sponses against pathogen associated molecular pat-terns(PAMPs)originating from the DNA or RNA of pathogens.The pivotal role of STING in host defense is exemplified by the fact that STING-/-mice die upon infection by HSV-1.Thus,STING plays an essential role in innate immune responses against pathogens.This opens up an exciting possibility of targeting STING for development of adjuvant therapies to boost the im-mune defenses against invading microbes.Similarly,STING could be targeted for mitigating the inflamma-tory responses augmented by the innate immune sys-tem.This review summarizes and updates our current understanding of the role of STING in innate immune responses and discusses the future challenges in de-lineating the mechanism of STING-mediated responses. | Neil Shaw Songying Ouyang Zhi-Jie Liu | 2013 | Protein & Cell2013，4，2： | 1 |
| 18 | 显示文摘 | ZHAO JW SONGY P MA PT | 2009 | J Solid State Chem2009，182，7： | 1 |
| 19 | Structure of Severe Fever with Thromboeytopenia Syndrome Virus Nucleocapsid protein in Complex with Suramin Reveals Therapeutic Potentials显示文摘 | Lianying Jiao Songying Ouyang Mifang Liang | 2014 | J Virol Aprilm2014，88，73： | 1 |
| 20 | Deregulated expression of Notch re- ceptors in human hepatocenular carcinoma 显示文摘 | Gao J Songy Z Chen Y | 2008 | Dig Liver Dis2008，40，2： | 1 |
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