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3篇 您的检索式:作者名="Solmaz Assa"
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1Rectal administration of d-alpha tocopherol for active ulcerative colitis:A preliminary report显示文摘AIM: To investigate the anti-oxidant and anti-neutrophil recruitment effects of rectal d-alpha (d-α) tocopherol administration on mild and moderately active ulcerative colitis (UC). METHODS: Fifteen patients with mild and moderately active ulcerative colitis were enrolled in an open-label study of d-α tocopherol enema (8000 U/d) for 12 wk. All patients were receiving concomitant therapy with 5-aminosalicylic acid derivatives (5-ASA) and/or immunomodulator medications. Endoscopic evaluation was performed at baseline and after 4th and 12th weeks. Disease activity was measured with the Mayo disease activity index (DAI) and remission was defined as DAI of ≤ 2 with no blood in stool. Clinical response was defined as a DAI reduction of ≥ 2. RESULTS: At the end of 12th week,the average DAI score significantly decreased compared to the beginning of the study (2.3 ± 0.37 vs 8 ± 0.48,P < 0.0001). One patient was withdrawn after 3 wk for being unavailable to follow-up. On the 4th week of therapy,12 patients showed clinical response,3 of whom (21.4%) achieving remission. After 12 wk,all 14 patients responded clinically to the therapy and remission was induced in 9 of them (64%). No patient reported adverse events or was hospitalized due to worsened disease activity. CONCLUSION: This preliminary report suggests that rectal d-α tocopherol may represent a novel therapy for mild and moderately active UC. The observed results might be due to the anti-inflammatory and anti-oxidative properties of vitamin E.Seyed Amir Mirbagheri Behtash Ghazi Nezami Solmaz Assa Mannan Hajimahmoodi 2008World Journal of Gastroenterology2008,14,39:4
2Chronic lithium treatment protects the rat kidney against ischemia/reperfusion injury: The role of nitric oxide and cyclooxygenase pathways显示文摘Saman Shafaat Talab Hamed Emami Azadeh Elmi Behtash Ghazi Nezami Solmaz Assa Armin Farajzadeh Deroee Ali Daneshmand Seyed Mohammad Tavangar Ahmad Reza Dehpour 2010European Journal of Pharmacology2010,,1:1
3Chronic Upregulation of the Endogenous Opioid System Impairs the Skin Flap Survival in Rats显示文摘Behtash Ghazi Nezami Saman Shafaat Talab Hamed Emami Solmaz Assa Mohammad Reza Rasouli Shahrzad Asadi Seyed Mohammad Tavangar Ahmad Reza Dehpour 2009Annals of Plastic Surgery2009,,5:1
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