2篇
您的检索式：作者名="Simone Frea"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Berberine behind the thriller of marked symptomatic bradycardia显示文摘Berberine is used in traditional Chinese medicine for the treatment of congestive heart failure, hypertension, diabetes, and dyslipidaemia and has a good safety profile. We report a case of a 53-year-old sportsman referred to our hospital for the onset of fatigue and dyspnoea upon exertion after he started berberine to treat hypercholesterolaemia. An electrocardiogram showed sinus bradycardia (45 bpm), first-degree atrioventricular block, and competitive junctional rhythm. An ergometric stress test showed slightly reduced chronotropic competence and the presence of runs of competitive junctional rhythm, atrial tachycardia, and sinus pauses in the recovery. After 10 d of wash-out from berberine, the patient experienced a complete resolution of symptoms, and an ergometric stress test showed good chronotropic competence. An electrocardiogram Holtershowed a latent hypervagotonic state. This is the first case report that shows that berberine could present certain side effects in hypervagotonic people, even in the absence of a situation that could cause drug accumulation. Therefore, berberine's use should be carefully weighed in hypervagotonic people due to the drug's bradycardic and antiarrhythmic properties, which could became proarrhythmic, exposing patients to potential health risks. | Margherita Cannillo Simone Frea Cristina Fornengo Elisabetta Toso Giancarlo Mercurio Stefania Battista Fiorenzo Gaita | 2013 | World Journal of Cardiology2013，5，7： | 3 |
| 2 | Meta-Analysis of the Usefulness of Mitraclip in Patients With Functional Mitral Regurgitation显示文摘 | Fabrizio D’ascenzo Claudio Moretti Walter Grosso Marra Antonio Montefusco Pierluigi Omede Salma Taha Davide Castagno Oliver Gaemperli Maurizio Taramasso Simone Frea Stefano Pidello Volker Rudolph Olaf Franzen Daniel Braun Cristina Giannini Huseyin Ince Le | 2015 | The American Journal of Cardiology2015，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员