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| 1 | Incidence of gallstone disease in Italy:Results from a multicenter,population-based Italian study (the MICOL project)显示文摘AIM:To evaluate gallstone incidence and risk factors in a large population-based study. METHODS: Gallstone incidence and risk factors, were evaluated by structured questionnaire and physical examination, respectively, in 9611 of 11 109 (86.5%) subjects who were gallstone-free at the cross-sectional study. RESULTS: Six centers throughout Italy enrolled 9611 subjects (5477 males, 4134 females, aged 30-79 years), 9517 of whom were included into analysis: 424 subjects (4.4%) had gallstones and 61 (0.6%) had been cholecystectomized yielding a cumulative incidence of 0.67% per year (0.66% in males, 0.81% in females). Increasing age, a high body mass index (BMI), a history of diabetes, peptic ulcer and angina, and low cholesterol and high triglyceride levels were identifi ed as risk factors in men while, in females, the only risk factors were increasing age and a high BMI.Increasing age and pain in the right hypocondrium in men and increasing age in females were identifi ed as predictors of gallstones. Pain in the epigastrium/ right hypocondrium was the only symptom related to gallstones; furthermore, some characteristics of pain (forcing to rest, not relieved by bowel movements) were significantly associated with gallstones. No correlation was found between gallstone characteristics and clinical manifestations, while increasing age in men and increasing age and BMI in females were predictors of pain. CONCLUSION:Increasing age and BMI represent true risk factors for gallstone disease (GD); pain in the right hypocondrium and/or epigastrium is confi rmed as the only symptom related to gallstones. | Davide Festi Ada Dormi Simona Capodicasa Tommaso Staniscia Adolfo F Attili Paola Loria Paolo Pazzi Giuseppe Mazzella Claudia Sama Enrico Roda Antonio Colecchia | 2008 | World Journal of Gastroenterology2008，14，34： | 23 |
| 2 | 显示文摘 | Simona S Giancarlo F Sandro C | 2007 | Journal of Molecu lar Catalysis B: Enzymatic2007，44，3： | 1 |
| 3 | Phenotypic and functional characteristics of tumor-derived microvascular endothelial cells显示文摘 | Giulio A Renato GS Simona F | 1999 | Clin Expe Metast1999，17，： | 1 |
| 4 | Modeling the alpha-helix to beta-hairpin transition mechanism and the formation of oligomeric aggregates of the fibrillogenic peptide Abeta (12-28):insights from all-atom molecular dynamics simulations显示文摘 | SIMONA F TIANA G BROGLIA RA | 2004 | J Mol Graph Model2004，23，3： | 1 |
| 5 | Prognostic value of cystatin C in acute coronary syndromes:enhancer of atherosclerosis and promising therapeutic target 显示文摘 | Simona F Giuseppe M Elia MB | 2011 | Clin Chem Lab Med2011，49，9： | 1 |
| 6 | Giant piezoelectric effect in GaN self-assembled quantum dots显示文摘 | Simona J Pelekanosa N T | 1999 | Microelectronics Journal1999，30，： | 1 |
| 7 | Horseradish peroxidase in ionic liquids reactions with water insoluble phenolic substrates显示文摘 | Simona S Giancarlo F Sandro C | | 0，，： | 1 |
| 8 | Antioxidant activity of phenolic and phenylethanoid glycosides from Teucrium polium L显示文摘 | Simona DM Carmen F Franco Z | | 0，，01： | 1 |
| 9 | Horseradish peroxides in i- onic liquids reactions with water insoluble phenolic substrates显示文摘 | Simona S Giancarlo F Sandro C | 2007 | Journal of Molecular Catalysis B : Enzymatic2007，44，3： | 1 |
| 10 | CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB/WF1 mice显示文摘 | Juergen F Simona S Robert SM | 2003 | J Clin Invest2003，111，10： | 1 |
| 11 | Contribution of pro- teomics to understanding the role of tumor-derived exo- somes in cancer progression: State of the art and new per- spectives 显示文摘 | Simona F Laura S Simona T | 2013 | Proteomics2013，13，： | 1 |
| 12 | Formation of Coloured Maillard reaction Products in a Glutenglucose ModelSystem显示文摘 | Vincenzo F Simona M M Teresa M | 1999 | Food Chemistry1999，66，： | 1 |
| 13 | Sertoli-Leydig cell tumor - a rare androgen secreting ovarian tumor in postmenopausal women显示文摘 | Ancuta GG Simona F Dana C | 2003 | J Cell Mol Med2003，7，4： | 1 |
| 14 | A metrological comparison between different methods for harmonic pollution metering显示文摘 | ALESSANDRO F MARCO P SIMONA S | 2012 | IEEE Transactions on Instrumentation and Measurement2012，61，11： | 1 |
| 15 | β cells are responsible for CXCR3 mediated T-cell infiltration in insulitis 显示文摘 | Simona F Tobias J Bao L | 2002 | Nat Med2002，8，12： | 1 |
| 16 | Biochemical basis for retinol deficiency induced by the 141N and G75D mutations in human plasma retinol-binding protein 显示文摘 | Claudia F Simona V Marco B | 2005 | Biochemical and Biophysical Research Communications2005，336，： | 1 |
| 17 | Optimization of mid-dilution hemodiafiltration:technique and performance显示文摘 | Luciano AP Annalisa F Simona Z | 2009 | Nephrol Dial Transplant2009，24，5： | 1 |
| 18 | A Fourth-Order Single-Bit Switched-Capacitor E- A Modulator for Distributed Sensor Applications 显示文摘 | Simona B Fabrizio F Piero M | 2004 | IEEE Transactions on Instrumentation and Meas- urement2004，53，2： | 1 |
| 19 | Behavioral modeling of switch capacitor sigma delta modulators 显示文摘 | Piero M Simona B Fabrizio F | 2003 | IEEE Transanctions on Circuits and Systems- I2003，50，3： | 1 |
| 20 | Towards Automatic Systems Architecting 显示文摘 | Simona F Pinheiro G Loureiro G | 2007 | Complex Systems Concurrent Engineering2007，，： | 1 |
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