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257篇 您的检索式:作者名="Simko"
    题名 作者 年代 出处 被引量
1Multiplex biomarker approach to cardiovascular diseases显示文摘个性化的药部分基于指导 biomarker 的诊断,治疗和预后,它在现代心病学正在成为一个不可避免的概念。然而,单个 biomarker 研究的临床的意义是相当有限的。一条有希望的新奇途径涉及把多重标记合为一块复合面板,它能与心血管的病理精制一个特别病人的管理。二种主要不同的试金格式被开发了便于多重抗原的同时的 quantification:平面数组试金和 microbead 试金。这些途径可以帮助更好评估复杂性和病理学的过程的动态自然并且与传统的连接酶的 immunosorbent 相比提供实质的费用和样品积蓄试金(ELISA ) 大小。然而,一条复合 multimarker 途径不能成为一个通常传播的方法直到分析问题被解决并且推进研究证实改进临床的结果被完成。这些缺点位于一小部分系统的研究迄今为止关于在心血管的药的一条复合 biomarker 途径的使用是可得到的事实下面。我们的观点在临床、试验性的心脏病专家的密切合作下面在一个更宽的概念的框架强调复合途径的使用的重要潜力, pathophysiologists 和生物化学家以便个性化的途径可以基于测试的标准化 multimarker 改进各种各样的心血管的病理的管理并且成为导出人口的基于证据的药的一个无所不在的搭挡。Michaela ADAMCOVA Fedor SIMKO 2018Acta Pharmacologica Sinica2018,39,7:3
2Enigmatic lipoprotein (a) and cardiovascular dis - ease显示文摘Ginter E Simko V 2010Bratisl Lek Listy2010,111,10:1
3Influence of Cooking in Content in Smoked Sausages显示文摘Simko P Gergely S Karovicova J 1993Meat Science1993,34,:1
4Determination of polycyclic aromatic hydrocarbons in smoked meat products and smoke favoring food additives显示文摘SIMKO P 2002Journal of Chromatography B2002,770,:1
5Chronic antioxidant therapy fails to ameliorate hypertension: potential mechanisms mechanisms显示文摘Pechanova O Simko F 2009J Hypertens Suppl2009,27,6:1
6The role of nitric oxide in the maintenance of vasoaetive balance 显示文摘PECHANOVA O SIMKO F 2007Physiol Res2007,56,2:1
7The Balance Sheet as an Earnings Management Constraint 显示文摘Barton J Simko P 2002Accounting Review2002,77,4:1
8The role of nitric oxide in the maintenance ofvasoactive balance显示文摘Pechanova O Simko F 2007Physiol Res2007,56,2:1
9Up-front therapy for LCH : is it time to test an alternative to vinblastine/prednisone? 显示文摘Simko SJ McClain KL Allen CE 2015British Journal of Haematology2015,169,2:1
10What is the perceived quality of life of adults with congenital heart disease and does it differ by anomaly显示文摘Simko LC McGinnis KA 2005J Cardiovasc Nurs2005,20,3:1
11Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro:possible immune cell activation显示文摘Simko M Mattsson MO 2004J Cell Biochem2004,93,1:1
12Induction of cell activation processes by low frequency electromagnetic fields 显示文摘Simko M 2004Sci World J2004,4,2:1
13Statins: a perspective for left ventricular hypertrophy treatment显示文摘Simko F 2007Eur J Clin Invest2007,37,9:1
14Differences in laboratory findings for cerebrospinal fluid specimens obtained from patients with meningitis or encephalitis due to herpes simplex virus (HSV) documented by detection of HSV DNA显示文摘SIMKO JP CALIENDO AM HOGLE K 2002Clin Infect Dis2002,35,4:1
15Determination of synthetic phenolic antioxidants in food by high performance liquid chro- matography 显示文摘KAROVICOVA J SIMKO P 2000J Chromatogr A2000,882,12:1
16Surgical treatment of intra-articular calcaneal fractures显示文摘Popelka V Simko P 0,,02:1
17Left ventricular hypertrophy regression as a process with variable biological implications显示文摘 1996Can J Cardiol1996,,:1
18Effects of the flaxseed lignana secoisolaricircsinol diglucoside and its aglycone on serum and hepatic lipids in hypedipidaemic rats显示文摘WOO G SIMKO E KROL E S 2009Br J Nutr2009,102,3:1
19The Balance Sheet as an Earnings Management Constraint显示文摘Barton J Simko P 2002The Accounting Review2002,,77:1
20Vacuum glazing—A new component for insulating windows显示文摘R.E. Collins G.M. Turner A.C. Fischer-Cripps J.-Z. Tang T.M. Simko C.J. Dey D.A. Clugston Q.-C. Zhang J.D. Garrison 1995Building and Environment1995,,4:1
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