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| 1 | Relationship between Crohn’s disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patients显示文摘AIM: To study the association between Crohn’s disease (CD), Mycobacterium avium subspecies paratubercu- losis (MAP), and genetic factors by examining the role of natural resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms (now SLC11A1) in Sar dinian patients with CD and controls. METHODS: Thirty-seven CD patients and 34 controls with no inflammatory bowel disease (IBD) were recruited at the University of Sassari after giving written con sent. Six SCL11A1 polymorphisms previously reported to be the most significantly associated with IBD were searched. M. paratuberculosis was identified by IS900 PCR and sequencing. Logistic regression was used to cal culate odds ratios (OR) for the associations among CD presence of MAP, and 6 loci described above. RESULTS: For the first time, a strong association was observed between polymorphisms at NRAMP1 locus 823C/T and CD. While CD was strongly associated withboth NRAMP1 and MAP, NRAMP1 polymorphisms and MAP themselves were not correlated. CONCLUSION: Combined with previous work on the NOD2/CARD15 gene, it is clear that the interplay of ge- netic, infectious, and immunologic factors in the etiology of CD is complex. | Leonardo A Sechi Maria Gazouli Lee E Sieswerda Paola Molicotti Niyaz Ahmed John Ikonomopoulos Antonio M Scanu Daniela Paccagnini Stefania Zanetti | 2006 | World Journal of Gastroenterology2006，12，44： | 3 |
| 2 | Early life history of the starry flounder, Platichthys stellatus, reared through metamorphosis in the laboratory显示文摘 | POLICANSKY D SIESWERDA P | 1979 | Transactions of the American Fisheries Society1979，108，： | 1 |
| 3 | Effects of high- dose insulin infusion on left ventricular function in normal subjects 显示文摘 | Klein LJ van Campen CMC Sieswerda GT | 2010 | Neth Heart2010，18，4： | 1 |
| 4 | Omega-3 fatty acids in affective and psychotic disorders 显示文摘 | Ross BM Sieswerda LE | 2006 | Omega-3 Fatty Acid Res2006，，： | 1 |
| 5 | Assessment of Myocardial Reperfusion by Intravenous Myocardial Contrast Echocardiography and Coronary Flow Reserve After Primary Percutaneous Transluminal Coronary Angiography in Patients With Acute Myocardial Infarction显示文摘 | Wolfgang Lepper Rainer Hoffmann Otto Kamp Andreas Franke Carel C. de Cock Harald P. Kühl Gertjan T. Sieswerda Jürgen vom Dahl Uwe Janssens Paolo Voci Cees A. Visser Peter Hanrath | 2000 | Circulation: Journal of the American Heart Association2000，，20： | 1 |
| 6 | Predictive value of markers of myocardial reperfusion in acute myocardial infarction for follow-up left ventricular function显示文摘 | Lepper W Sieswerda GT Vanoverschelde JL | 2001 | Am J Cardiol2001，88，12： | 1 |
| 7 | Schema modes and childhood abuse in borderline and antisocial personality disorders 显示文摘 | Lobbestael J Amtz A Sieswerda S | 2005 | J Behav Ther Exp Psychiatry2005，36，3： | 1 |
| 8 | Predictive value of markers of myocardial reperfusion in acute myocardial infarction for follow-up left ventricular function显示文摘 | Lepper W Sieswerda GT | 2001 | Am J Cardiol2001，88，： | 1 |
| 9 | Comparison of effects on systolic and diastolic left ventricular function of nebivolol versus atenolol in patients with uncomplicated essential hypertension 显示文摘 | KAMP O SIESWERDA GT VISSER CA | 2003 | Am J Cardiol2003，92，3： | 1 |
| 10 | Early life history of the starry flounder, Platichthys stellatus, reared through metamorphosis in the laboratory 显示文摘 | David Policansky Paul Sieswerda | 1979 | Transactions of the American Fisheries Society1979，108，： | 1 |
| 11 | Predictive value of make is of myocardial reperfusion in acute myocardial infarction of follow-up left ventricular function显示文摘 | Lepper W Sieswerda GT Vanoversehelds JL | 2001 | Am J Cardiol2001，88，12： | 1 |
| 12 | Predictive value of markers of myocardial reperfusion in acute myocardial infarction for follow-up left ventricular function显示文摘 | Lepper W Sieswerda GT Vanoverschelde JL | 2001 | Am J Cardiol2001，88，： | 1 |
| 13 | Predictive value of markers of myocardial reperfusion in acute myocardial infarction for follow-up left ventricular function显示文摘 | Wolfgang Lepper Gertjan Tj Sieswerda Jean Louis Vanoverschelde Andreas Franke Carel C de Cock Otto Kamp Harald P Kühl Agnes Pasquet Paolo Voci Cees A Visser Peter Hanrath Rainer Hoffmann | 2001 | The American Journal of Cardiology2001，，12： | 1 |
| 14 | Quantitative evaluation of myocardial perfusion in patients with revascularized myocardial infarction:comparison between intravenous myocardial contrast echocardiography and 99mTc-sestamibi single photon emission computed tomography显示文摘 | Sieswerda G T Klein L J Kamp O | 2004 | Eur J Echocardiogr2004，5，： | 1 |
| 15 | Predictive value of markers of myocardial reperfusion in acute myocardial infarction for follow-up left ventricular function 显示文摘 | Lepper W Sieswerda GT Vanoverschelde JL | 2001 | Am J Cardiol2001，88，12： | 1 |
| 16 | Intravenous myocardial contrast echocardiography predicts left ventricular remodeling in patients with acute myocardial infarction显示文摘 | Wolfgang Lepper Otto Kamp Jean Louis Vanoverschelde Andreas Franke Gertjan Tj. Sieswerda Agnes Pasquet Harald P. Kühl Paolo Voci Cees A. Visser Peter Hanrath Rainer Hoffmann | 2002 | Journal of the American Society of Echocardiography2002，，： | 1 |
| 17 | Predictive value of markers of myocardial reperfusion in acute myocardial infarction for follow-up left ventdcular function显示文摘 | Lepper W Sieswerda GT Vanoverschelde JL | 2001 | Am J Cardiol2001，88，： | 1 |
| 18 | Quantitative evaluation of myocardial perfusion in patients with revascularized myocardial infarction:comparison between intravenous myocardial contrast echocardiography and 99m Tc-sestamibi single photon emission computed tomography显示文摘 | Sieswerda GT Klein LJ Kamp O | 2004 | Eur J Echocardiog2004，5，1： | 1 |
| 19 | The use of liposomal anthracycline analogues for childhood malignancies;A systematic review显示文摘 | Sieswerda E Kremer LC Caron HN | | 0，，： | 1 |
| 20 | Quantification of myocardialperfusion using intravenous myocardial contrast echocardiography in healthyvolunteers:comparison with positron emission tomography显示文摘 | Dijkmans PA Knaapen P Sieswerda GT | 2006 | J Am Soc Ech-ocardiogr2006，19，3： | 1 |
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