|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The classification and assessment of freeze-thaw erosion in Tibet显示文摘Freeze-thaw erosion is the third largest soil erosion type after water erosion and wind erosion. Restricted by many factors, few researches on freeze-thaw erosion have so far been done at home and abroad, especially those on the assessment method of freeze-thaw erosion. Based on the comprehensive analysis of impact factors of free-thaw erosion, this paper chooses six indexes, including the annual temperature range, annual precipitation, slope, aspect, vegetation and soil, to build the model for relative classification of freeze-thaw erosion using weighted and additive methods, and realizes the relative classification of the freeze-thaw erosion in Tibet with the support of GIS software. Then a synthetic assessment of freeze-thaw erosion in Tibet has been carried out according to the relative classification result. The result shows that the distribution of freeze-thaw eroded area is very extensive in Tibet, accounting for 55.3% of the total local land area; the spatial differentiation of freeze-thaw erosion with different intensities is obvious; and the difference in distribution among different regions is also obvious. | ZHANG Jianguo LIU Shuzhen YANG Siquan | 2007 | Journal of Geographical Sciences2007，17，2： | 12 |
| 2 | Effect of different sources and levels of iron in the diet of sows on iron status in neonatal pigs显示文摘This study was conducted to determine the effects of maternal dietary supplementation of ferrous glycine chelate(Fe-Gly) and ferrous sulfate monohydrate(FeSO_4·H_2O) on the relative organ weight, tissue iron contents, red blood cells(RBC), hemoglobin concentration(HGB) and hematocrit(HCT) in blood, as well as ferritin(Fn), serum iron(SI), and total iron binding capacity(TIBC) in serum of newborn piglets.Forty-five sows(Landrace × Large white, mean parity 3 to 4, no significant differences in BW) were randomly allotted to 9 treatments(n=5 sows/treatment): control(basal diet with no Fe supplementation), the basal diet supplemented with 50, 80, 110 or 140 mg Fe/kg as Fe-Gly, and the basal diet supplemented with 50, 80, 110 or 140 mg Fe/kg as FeSO_4·H_2O.The neonatal piglets(n=45) were used to determine the relative organ weight, tissue iron contents and blood biochemical indices.Compared with the control, the relative weight of spleen and kidney were significantly increased(P < 0.05) in the Fe-Gly groups.The iron contents in liver,spleen, kidney and femur were also found increased(P < 0.05) in the Fe-Gly groups.The RBC(d 1 and 21),HGB(d 1 and 21) and HCT(d 1 and 21) in blood and Fn(d 1) and SI(d 1 and 21) significantly increased(P < 0.05), but the TIBC(d 1 and 21) in serum decreased(P < 0.05) in the Fe-Gly groups.Moreover, the kidney relative weight, iron content in liver, spleen, kidney and femur, RBC(d 1) and HGB(d 21) in blood, and SI(d 1)in the Fe-Gly groups increased(P < 0.05) compared with the FeSO_4·H_2O treatment.Linear and quadratic responses of the kidney relative weight, the iron content in liver, spleen, kidney and femur, RBC(d 1 and 21),HGB(d 1 and 21) and HCT(d 1 and 21) in whole blood, SI(d 1) and TIBC(d 1 and 21) in the Fe-Gly groups were observed(P < 0.05).Linear responses of Fn(d 1 and 21) and SI(d 21) in the Fe-Gly groups, and spleen relative weight, HCT(d 1), Fn(d 1) and TIBC(d 1 and 21) in the FeSO_4·H_2O groups were observed(P < 0.05).These finding suggest that Fe-Gly supplemented at the level of 110 mg/kg in the diet of sows in this experiment is superior to other forms of supplementation, based on HGB concentration, the relative organ weight, tissue iron contents and blood biochemical indices of piglets. | Yan Li Weiren Yang Donghua Dong Shuzhen Jiang Zaibin Yang Yuxi Wang | 2018 | Animal Nutrition2018，，2： | 11 |
| 3 | A Study of Tensile Strength Tests of Arborous Species Root System in Forest Engineering Technique of Shallow Landslide显示文摘One experiment was conducted, through tensile tests of Albazzia and Eucalypt roots culled from the fields. The other experiment was conducted, by testing anti-drawing strength of these root systems in the Albazzia and Eucalypt lands. These two experiments had an aim to give insights into the maximum tensile strength and anti-drawing strength of the root systems. Results indicated that the maximum tensile strength of root system is in an exponential relation with the diameter of root system while the maximum tensile strength is positively correlative with the diameter of root system. Anti-drawing force of root system together with root diameter, length, and soil bulk density are folded into a regression equation in an attempt to figure out the static friction coefficient between root system and its ambient soil. | YANG Yonghong LIU Shuzhen WANG Chenghua TANG Chuan | 2006 | Wuhan University Journal of Natural Sciences2006，11，4： | 6 |
| 4 | Effects of purified zearalenone on selected immunological and histopathologic measurements of spleen in post-weanling gilts显示文摘The present study was aimed at investigating the adverse effects of dietary zearalenone(ZEA) on the lymphocyte proliferation rate(LPR), interleukin-2(IL-2), mRNA expressions of pro-inflammatory cytokines, and histopathologic changes of spleen in post-weanling gilts. A total of 20 crossbred piglets(Yorkshire × Landrace × Duroc) with an initial BW of 10.36 ± 1.21 kg(21 d of age) were used in the study.Piglets were fed a basal diet with an addition of 0.1.1,2.0, or 3.2 mg/kg purified ZEA for 18 d ad libitum.The results showed that LPR and IL-2 production of spleen decreased linearly(P < 0.05) as dietary ZEA increased. Splenic mRNA expressions of interleukin-1β(IL-1β) and interleukin-6(IL-6) were linearly upregulated(P < 0.05) as dietary ZEA increased. On the contrary, linear down-regulation(P<0.05) of mRNA expression of interferon-γ(IFN-γ) was observed as dietary ZEA increased. Swelling splenocyte in1.1 mg/kg ZEA treatments, atrophy of white pulp and swelling of red pulp in 2.0 and 3.2 mg/kg ZEA treatments were observed. The cytoplasmic edema in 1.1 mg/kg ZEA treatments, significant chromatin deformation in 2.0 mg/kg ZEA treatment and phagocytosis in 3.2 mg/kg ZEA treatment were observed.Results suggested that dietary ZEA at 1.1 to 3.2 mg/kg can induce splenic damages and negatively affect immune function of spleen in post-weanling gilts. | Peng Chen Tingjun Liu Shuzhen Jiang Zaibin Yang Libo Huang Faxiao Liu | 2017 | Animal Nutrition2017，，3： | 5 |
| 5 | Effects of purified zearalenone on selected immunological measurements of blood in post-weaning gilts显示文摘Zearalenone(ZEA), an estrogenic mycotoxin, is produced mainly by Fusarium fungi. Previous studies have indicated that acute ZEA exposure induced various damages in different species; however, its transparent hematotoxicity in female piglets at dietary levels of 1.1 to 3.2 mg/kg has not been shown. The present study was conducted to investigate the effects of dietary ZEA(1.1—3.2 mg/kg) on hematology, T lymphocyte subset, immunoglobulin, antibody titer, lymphocyte proliferation rate(LPR), and interleukin-2(IL-2) in peripheral blood of post-weaning gilts. A total of 20 female piglets(Landrace × Yorkshire × Duroc),weaned at 42 d with an average body weight of 10.36 ± 1.21 kg were used in the study. Female piglets were kept in a temperature controlled room, divided into four treatments, and fed a diet based on corn-soybean meal-fishmeal-whey, with an addition of 0, 1.1, 2.0, or3.2 mg/kg purified ZEA for 18 d ad libitum. Feed intake and refusal were measured daily and individual pigs were weighed weekly. Blood and serum samples were collected for selected immunological measurements. Female piglets fed different levels of dietary ZEA grew similarly with no difference in feed intake. Hematological values including leukocytes, platelets, lymphocytes, hematocrit, and mean corpuscular hemoglobin(MCH) decreased linearly(P < 0.05) as dietary ZEA increased. Female piglets fed diets containing 2.0 mg/kg ZEA or greater showed significantly decreased CD4+CD8+, CD4+, and CD4+/CD8^+ in comparison to the control(P < 0.05), whereas CD8^+ was significantly increased(P = 0.026) in the gilts which were fed the diet containing 3.2 mg/kg ZEA. Serum immunoglobulin G(IgG) and the antibody titer on d 18 were reduced linearly as dietary ZEA levels increased(P < 0.001). Linear decrease in LPR was observed(P < 0.05). Female piglets fed diets containing 2.0 mg/kg ZEA or more showed significantly decreased IL-2 in comparison to the control(P < 0.05). The results suggested that dietary ZEA at the levels of 1.1 to 3.2 mg/kg can induce different degrees of hematotoxicity and negatively affect immune function in female piglets. | Lijie Yang Weiren Yang Qiang Feng Libo Huang Guiguo Zhang Faxiao Liu Shuzhen Jiang Zaibin Yang | 2016 | Animal Nutrition2016，，3： | 5 |
| 6 | 152 W high-power blue diode laser operated at 447 nm显示文摘We demonstrate a high-power blue diode laser operated at 447 nm combining laser diodes using an optical fiber bundle. As many as 127 diode lasers at 447 nm were coupled into 400 μm/0.22 NA fibers using an aspherical lens group with different focus lengths. The bare fibers were mechanically bundled through high temperature ultraviolet adhesive after the coatings of the 127 fibers were stripped. The diameter of the fiber bundle was 6 mm. The total output power of such a bundle was 152 W with electro-optical conversion efficiency of 27.56%and the RMS power instability was less than ±1% within 3 h. | Peng Wu Ling Zhang Haijuan Yu Xiandan Yuan Zhiyan Zhang Pengfei Zhao Shuzhen Zou Chaojian He Yaoyao Qi Yingying Yang Gang Li Xubao Wang Xuechun Lin | 2017 | Journal of Semiconductors2017，38，7： | 4 |
| 7 | Prognostic significance of combining high mobility group Box-1 and OV-6 expression in hepatocellular carcinoma显示文摘The inflammatory environment and existence of cancer stem cells are critical for progression and intrahepatic recurrence of hepatocellular carcinoma(HCC) after curative resections. Here, we investigated the prognostic significance of combining high mobility group box 1(HMGB1) expression and hepatic progenitor marker OV6 in hepatocellular carcinoma. Expression of HMGB1 and OV6 was evaluated using immunohistochemistry profiling in tissue microarrays containing samples from 208 HCC patients. Invasive clinical or pathological factors were found in patients with high expression of HMGB1 or OV6. Higher HMGB1 was associated with poorer clinical outcomes, and independently related to elevated 5-year recurrence incidence(85.5% vs. 62.4%, P<0.001). We also found that more OV6 positive staining was correlated with poor prognosis of HCC patients(P<0.001). Notably, expression of HMGB1 was positively correlated with OV6 in density(R2=0.032, P<0.001) and reversely related to HCC outcomes. Abnormal expression of HMGB1 in combination with positive staining of OV6 displayed poorer prognostic performance than single biomarker alone(area under curve(AUC) survival=0.696). Therefore, HMGB1 and OV6 positive staining are promising prognostic parameters for HCC, and we propose that HMGB1 and OV6 may cooperate with each other and predict poor prognosis of HCC. | Jihui Zhu Han Yu Shuzhen Chen Pinghua Yang Zihui Dong Yan Ling Hao Tang Shilei Bai Wen Yang Liang Tang Feng Shen Hongyang Wang Wen Wen | 2018 | Science China(Life Sciences)2018，61，8： | 4 |
| 8 | Neuroprotective effect of Longshengzhi capsule following permanent middle cerebral artery occlusion in rats显示文摘Objective:Longshengzhi capsule(LSZC)is an optimized preparation based on the traditional Chinese Medicine formula Buyanghuanwu Decoction(BYHWD),and is approved by the China Food and Drug Administration for treating stroke-induced disability and vascular diseases.Herein,we examined the pharmacodynamics,anti-apoptotic and anti-oxidant actions,and potential mechanisms of action of LSZC following stroke in rats.Methods:Permanent middle cerebral artery occlusion(MCAO)was used as an ischemic stroke model.LSZC was administered intragastrically.We examined the survival rate,bodyweight,and neurological deficits in stroke rats.Brain infarct size was determined by 2,3,5-triphenyltetrazolium chloride staining.Brain pathology was examined using hematoxylin and eosin staining,Nissl staining,and TdT-mediated dUTP Nick-End Labeling staining.Malondialdehyde,catalase,superoxide dismutase,and glutathione levels were examined by commercial kits.Expression of Nrf2,heme oxygenase-1,Bax,Bcl-2,cleaved caspase-3,and caspase-3 proteins in brain tissue was measured by Western blot.Results:LSZC markedly improved the survival rate and bodyweight,and reduced infarct volume and neurological deficit scores,in MCAO stroke rats.LSZC also significantly attenuated oxidative stress,as indicated by decreased expression of malondialdehyde,and upregulation of Nrf2,heme oxygenase-1,catalase,superoxide dismutase,and glutathione.Moreover,LSZC significantly decreased apoptosis,including a decrease in Bax and cleaved caspase-3 expression,and an increase in Bcl-2,as well as a reduction in numbers of apoptotic neurons.Conclusion:LSZC treatment is neuroprotective against ischemic stroke,potentially via reducing oxidative stress and apoptosis.The Nrf2 and apoptotic signaling pathways may play important roles in the antioxidant and anti-apoptotic actions of LSZC. | Xiaoli Sun Shuzhen Guo Yong Wang Bangze Fu Junjie Liu Yili Zhang Ruocong Yang Chun Li Jian Gao Li Gao Wei Wang | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，1： | 4 |
| 9 | Near-field 3D imaging approach combining MJSR and FGG-NUFFT显示文摘A near-field three-dimensional(3 D)imaging method combining multichannel joint sparse recovery(MJSR)and fast Gaussian gridding nonuniform fast Fourier transform(FGGNUFFT)is proposed,based on a perfect combination of the compressed sensing(CS)theory and the matched filtering(MF)technique.The approach has the advantages of high precision and high efficiency:multichannel joint sparse constraint is adopted to improve the problem that the images recovered by the single channel imaging algorithms do not necessarily share the same positions of the scattering centers;the CS dictionary is constructed by combining MF and FGG-NUFFT,so as to improve the imaging efficiency and memory requirement.Firstly,a near-field 3 D imaging model of joint sparse recovery is constructed by combining the MF-based imaging method.Secondly,FGG-NUFFT and reverse FGG-NUFFT are used to replace the interpolation and Fourier transform in MF-based imaging methods,and a sensing matrix with high precision and high efficiency is constructed according to the traditional imaging process.Thirdly,a fast imaging recovery is performed by using the improved separable surrogate functionals(SSF)optimization algorithm,only with matrix and vector multiplication.Finally,a 3 D imagery of the near-field target is obtained by using both the horizontal and the pitching interferometric phase information.This paper contains two imaging models,the only difference is the sub-aperture method used in inverse synthetic aperture radar(ISAR)imaging.Compared to traditional CS-based imaging methods,the proposed method includes both forward transform and inverse transform in each iteration,which improves the quality of reconstruction.The experimental results show that,the proposed method improves the imaging accuracy by about O(10),accelerates the imaging speed by five times and reduces the memory usage by about O(10~2). | WANG Shuzhen FANG Yang ZHANG Jin’gang LUO Mingshi LI Qing | 2019 | Journal of Systems Engineering and Electronics2019，30，6： | 3 |
| 10 | Screening of Transgenic Soybean Transformed by Means of Pollen-tube Using Kanamycin显示文摘Kanamycin was used to screen T0 seeds of the variety Dongnong 46 transformed by means of pollen-tube method. The results showed that 400 mg·L-1 kanamycin could inhibit growth of non-transgenic plants, and 2 positive plants were gotten combined with Gus dyeing and PCR detection. It is proved that this method is e-conomic and effective in preliminary screening the transgenic plants. | ZHANG Shuzhen XU Pengfei ZHANG Dayong LIN Shifeng LI Wenbin HAN Yingpeng YANG Chuanping | 2006 | Journal of Northeast Agricultural University(English Edition)2006，13，1： | 2 |
| 11 | Cellular localization of NLRP3 inflammasome显示文摘Infl ammasome is a large protein complex activated upon cellular stress or microbial infection,which triggers maturation of pro-inflammatory cytokines interleukin-1βand interleukin-18 through caspase-1 activation.Nod-like receptor family protein 3(NLRP3)is the most character-ized infl ammasome activated by various stimuli.However,the mechanism of its activation is unclear and its exact cellular localization is still unknown.We examined the potential co-localization of NLRP3 infl ammasome with mi-tochondria and seven other organelles under adenosine triphosphate,nigericin or monosodium urate stimulation in mouse peritoneal macrophages using confocal micros-copy approach.Our results revealed that the activated endogenous apoptosis-associated speck-like protein containing a CARD(ASC)pyroptosome forms in the cyto-plasm and co-localizes with NLRP3 and caspase-1,but not with any of the organelles screened.This study indicates that the ASC pyroptosome universally localizes within the cytoplasm rather than with any specifi c organelles. | Yan Wang Chen Yang Kairui Mao Shuzhen Chen Guangxun Meng Bing Sun | 2013 | Protein & Cell2013，4，6： | 2 |
| 12 | A COVID-19 Outbreak Emerging in a Food Processing Company——Harbin City,Heilongjiang Province,China,January-February 2021显示文摘Summary What is already known about this topic?The coronavirus disease 2019(COVID-19)epidemic in China had been effectively controlled for several months,but as the ambient temperature dropped,large gathering-initiated epidemics occurred in northern China,including Hebei,Liaoning,and Jilin provinces. | Lei Hou Hao Zhou Nanxi Meng Xue Yu Xin Wang Tuo Wang Jianfeng Zhang Yan Wang Shie Li Shuzhen Guo Jianxing Yu Muxin Chen Wenhui Shi Ning Xiao Chao Yang Jianxiang Liu | 2021 | China CDC weekly2021，3，32： | 2 |
| 13 | 北京地区2013–2017年细颗粒物爆发增长事件的演变特征及气象成因分析显示文摘本文详细分析了2013–2017年北京地区细颗粒物爆发增长事件的演变特征,并结合气态前体物和常规气象要素对3种事件类型(3h, 6h和9h事件)的污染来源及其气象成因进行了探讨。北京地区细颗粒物爆发增长事件呈逐年下降趋势,且多发生在秋冬季;事件的生消过程中NO2的增长速率远高于SO2,表明移动源的贡献要高于固定源。风向-风速-PM2.5的polar Plot结果表明,来自北京东南方向气团的污染物输送对于3h事件有较大影响, 9h事件受主要受局地排放及二次转化的影响, 6h事件则源于局地排放和区域传输的共同贡献。 | SHI Shuzhen LIU Zirui XU Zhongjun YANG Shuanghong LIU Jingda WANG Yuesi | 2020 | Atmospheric and Oceanic Science Letters2020，13，1： | 2 |
| 14 | Arsenic accumulation and speciation in maize as affected by in- oculation with arbuscular mycorrhizal fungus glomus mosseae 显示文摘 | YU Yang ZHANG Shuzhen HUANG Honglin | 2009 | Agric Food Chem2009，57，： | 1 |
| 15 | Establishment of a Breeding System of Disease-free Clean Canes of Sugarcane显示文摘 | Yang benpeng Zhang shuzhen | 2007 | The Proceedings of the China Association for Science and Technology2007，4，1： | 1 |
| 16 | Near field 3-D imaging approach for joint high-resolution imaging and phase error correction显示文摘This paper combines compressed sensing(CS) imaging theory and range migration algorithm(RMA), and then proposes a near-field three-dimensional(3-D) imaging approach for joint high-resolution imaging and phase error correction. Firstly, a sparse measurement matrix construction method based on a logistic sequence is proposed, which conducts nonlinear transformation for the determined logistic sequence, making it obey uniform distribution, then conducts sign function mapping, and generates the pseudorandom sequence with Bernoulli distribution, thus leading to good signal recovery under down-sampling and easy availability for engineering realization. Secondly, in combination with the RMA imaging approach, the dictionary with all scene information and phase error correction is constructed for CS signal recovery and error correction. Finally, the non-quadratic solution model jointing imaging and phase error correction based on regularization is built, and it is solved by two steps — the separable surrogate functionals(SSF) iterative shrinkage algorithm is adopted to realize target scattering estimate; the iteration mode is adopted for the correction of the dictionary model, so as to achieve the goal of error correction and highly-focused imaging. The proposed approach proves to be effective through numerical simulation and real measurement in anechoic chamber. The results show that,the proposed approach can realize high-resolution imaging in the case of less data; the designed measurement matrix has better non-coherence and easy availability for engineering realization.The proposed approach can effectively correct the phase error,and achieve highly-focused target image. | Yang Fang Baoping Wang Chao Sun Zuxun Song Shuzhen Wang | 2017 | Journal of Systems Engineering and Electronics2017，28，2： | 1 |
| 17 | Chemical constituents from the seeds of Alpinia katsumadai Hayata显示文摘 | WANG Xiaobing YANG Changshui HUA Shuzhen | | 0，，06： | 1 |
| 18 | Probing the connection of PBSs to the photosystems in Spirulina plat- ens/s by artificially induced fluorescence fluctuations 显示文摘 | LI Heng YANG Shuzhen XIE Jie | 2007 | Journal of Luminescence2007，，1： | 1 |
| 19 | Behavior of mercury in a soil–plant system as affected by inoculation with the arbuscular mycorrhizal fungus Glomus mosseae显示文摘 | Yang Yu Shuzhen Zhang Honglin Huang | 2010 | Mycorrhiza2010，，6： | 1 |
| 20 | Design of a novel chimeric peptide via dual blockade of CD47/SIRPαand PD-1/PD-L1 for cancer immunotherapy显示文摘Although immune checkpoint inhibition has been shown to effectively activate antitumor immunity in various tumor types,only a small subset of patients can benefit from PD-1/PD-L1 blockade.CD47 expressed on tumor cells protects them from phagocytosis through interaction with SIRPαon macrophages,while PD-L1 dampens T cell-mediated tumor killing.Therefore,dual targeting PD-L1 and CD47 may improve the efficacy of cancer immunotherapy.A chimeric peptide Pal-DMPOP was designed by conjugating the double mutation of CD47/SIRPαblocking peptide(DMP)with the truncation of PD-1/PD-L1 blocking peptide OPBP-1(8-12)and was modified by a palmitic acid tail.Pal-DMPOP can significantly enhance macrophage-mediated phagocytosis of tumor cells and activate primary T cells to secret IFN-γin vitro.Due to its superior hydrolysis-resistant activity as well as tumor tissue and lymph node targeting properties,Pal-DMPOP elicited stronger anti-tumor potency than Pal-DMP or OPBP-1(8-12)in immune-competent MC38 tumor-bearing mice.The in vivo anti-tumor activity was further validated in the colorectal CT26 tumor model.Furthermore,Pal-DMPOP mobilized macrophage and T-cell anti-tumor responses with minimal toxicity.Overall,the first bispecific CD47/SIRPαand PD-1/PD-L1 dual-blockade chimeric peptide was designed and exhibited synergistic anti-tumor efficacy via CD8^(+)T cell activation and macrophage-mediated immune response.The strategy could pave the way for designing effective therapeutic agents for cancer immunotherapy. | Zheng Hu Wanqiong Li Shaomeng Chen Danhong Chen Ran Xu Danlu Zheng Xin Yang Shuzhen Li Xiuman Zhou Xiaoshuang Niu Youmei Xiao Zhuoying He Huihao Li Juan Liu Xinghua Sui Yanfeng Gao | 2023 | Science China(Life Sciences)2023，66，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员