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2篇 您的检索式:作者名="Shingo Hamaguchi"
    题名 作者 年代 出处 被引量
1Inferior mesenteric arteriovenous fistula during treatment with bevacizumab in colorectal cancer patient: A case report显示文摘BACKGROUND Fistula formation is a severe adverse event related to antiangiogenetic agents such as bevacizumab and inferior mesenteric arteriovenous fistula(IMAVF) is a result of acquired factor, especially colon surgery. However, IMAVF occurs very rarely and there are few reports in patients during chemotherapy. We report a case of a patient who developed IMAVF during treatment with bevacizumab in metastatic colorectal cancer(mCRC) after colon surgery.CASE SUMMARY An 81-year-old man was diagnosed with descending colon cancer and underwent left hemicolectomy without any complications. He was definitely diagnosed with high-risk stage 2 and received tegafur-uracil plus leucovorin as adjuvant chemotherapy. Three years and 6 mo after the operation, the cancer relapsed with peritoneal dissemination. The patient underwent CyberKnife radiosurgery targeting the recurrent tumor and received chemotherapy with S-1 plus bevacizumab. At 1 year after chemotherapy, he complained of severe diarrhea, which is suspected drug-induced colitis. As diarrhea worsened despite the termination of treatment, he underwent colonoscopy and computed tomography (CT) scans that revealed edematous change from sigmoid to rectosigmoid colon. CT scans also revealed an aneurysm adjacent to the inferior mesenteric vein and multidetector CT angiography showed the IMAVF. Elective angiography confirmed the diagnosis of an IMAVF and it was successfully treated by arterial embolization. The patient resumed chemotherapy with only S-1 6 mo after embolization.CONCLUSION Clinicians should keep in mind the probability of severe diarrhea arose from IMAVF in mCRC patients treated with bevacizumab.Ayako Doi Hiroyuki Takeda Kumiko Umemoto Ryosuke Oumi Shinji Wada Shingo Hamaguchi Hidefumi Mimura Hiroyuki Arai Yoshiki Horie Takuro Mizukami Naoki Izawa Takashi Ogura Takako EguchiNakajima Yu Sunakawa 2020World Journal of Gastrointestinal Oncology2020,12,11:1
2A case of lymphoepithelioma-like carcinoma of the colon with ulcerative colitis显示文摘Yasuyuki Kojima Masatoshi Mogaki Ryo Takagawa Ikuko Ota Mitsutaka Sugita Shiho Natori Yohei Hamaguchi Haruki Kurosawa Tadao Fukushima Hidenobu Masui Shingo Fukazawa Shoji Yamanaka Yukio Tsuura Kaoru Nagahori 2007Journal of Gastroenterology2007,,2:1
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