|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Decreased miR-320 expression is associated with breast cancer progression, cell migration, and invasiveness via targeting Aquaporin 1显示文摘我们的以前的研究证明了 Aquaporin 1 (AQP1 ) 是在乳癌的 overexpressed。然而,机制留下逃犯。MicroRNA 320 (miR-320 ) downregulation 在癌症的各种各样的类型被报导了,并且它可以调整 AQP1 表示。在这研究, miR-320 和 AQP1 表情被量的反向的 transcription-PCR 调查,在 situ 杂交,和 immunohistochemistry。这些分子的 clinicopathological 含意也被分析。我们发现那 miR-320 表情在人的乳癌病人是在血浆和肿瘤织物的 downregulated。幸存分析证明 miR-320 的那减少的表情和 AQP1 的 overexpression 与更坏的预后被联系。酶试金证明 miR-320 否定地调整 AQP1 表示。另外,房间增长,移植,和侵略试金被执行在乳癌房间上调查 miR-320 的效果。我们的结果证明 miR-320 overexpression 由 downregulating AQP1 在乳癌房间禁止房间增长,移植,和侵略。这些观察建议 miR-320 downregulation 可以在乳癌提高 AQP1 表示,赞成肿瘤前进。我们的调查结果显示 miR-320 和 AQP1 可以在乳癌的治疗用作预示的 biomarkers 和治疗学的目标。 | Liang Luo Rui Yang Shaojie Zhao Yu Chen Shanchao Hong Ke Wang Tiejun Wang Jing Cheng Ting Zhang Daozhen Chen | 2018 | Acta Biochimica et Biophysica Sinica2018，50，5： | 6 |
| 2 | Effects of spatial distribution of soil parameters on soil moisture retrieval from passive microwave remote sensing显示文摘In this paper,we studied the effect of spatial distribution of soil parameters on passive soil moisture retrieval at pixel scale.First,we evaluated the forward microwave emission model and soil moisture retrieval algorithm accuracy through the observa-tion of field experiments.Then,we used soil parameters in different spatial distribution patterns,including random,normal,and uniform distribution,to determine the different levels of heterogeneity on soil moisture retrieval,in order to seek the rela-tionship between heterogeneity and soil moisture retrieval error.Finally,we conducted a controlled heterogeneity effect ex-periment measurements using a Truck-mounted Multi-frequency Radiometer(TMMR) to validate our simulation results.This work has proved that the soil moisture retrieval algorithm had a high accuracy(RMSE=0.049 cm3 cm 3) and can satisfy the need of this research.The simulation brightness temperatures match well with observations,with RMSE=9.89 K.At passive microwave remote sensing pixel scale,soil parameters with different spatial distribution patterns could have different levels of error on soil moisture estimation.Overall,we found that soil moisture with a random distribution in a satellite pixel scale can cause the largest error,with a normal distribution being the second,and a uniform distribution the least due to the smallest het-erogeneity. | ZHANG Tao ZHANG LiXin JIANG LingMei ZHAO ShaoJie ZHAO TianJie LI YunQing | 2012 | Science China Earth Sciences2012，55，8： | 5 |
| 3 | Assessment and analysis of microwave emissivity and transmissivity of a deciduous forest towards the estimate of vegetation biomass显示文摘Forests play an important role in the global carbon cycle and have a potential impact on global climatic change.Monitoring forest biomass is of considerable importance in understanding the hydrological cycle.Because of the problem of dense forest cover,no reliable method with which to retrieve soil moisture in forest areas from the microwave emission signature has been established.All of these issues relate to the microwave emissivity and transmissivity characteristics of a forest.The microwave emission contribution received by a sensor above a forest canopy comes from both the soil surface and the vegetation layer.To analyze the relationship of forest biomass and forest emission and transmissivity,a high-order emission model,the matrix-doubling model,which consists of both soil and vegetation models,was developed and then validated for a young deciduous forest stand in a field experiment.To simulate the emissivity and transmissivity of a deciduous forest in the L and X bands using the matrix-doubling model,the parameters of components of deciduous trees when the leaf area index varies from 1 to10 were generated by an L-system and a forest growth model.The emissivity and transmissivity of a forest and the relationships of these parameters to forest biomass are presented and analyzed in this paper.Emissivity in the L band when the leaf area index is less than 6 and at viewing angles less than 40°,and transmissivity in the L band are the most sensitive parameters in deciduous forest biomass estimation. | ZHANG ZhongJun YU XianChuan ZHAO ShaoJie CHAI LinNa | 2014 | Science China Earth Sciences2014，57，3： | 2 |
| 4 | A High-Performance Composite Epoxy Coating Based on the Cooperative Enhancement of 2D Co_(2)(OH)2BDC and Electrospun PAN Nanofiber Membrane显示文摘Based on a two-dimensional(2D)Co-MOF(Co_(2)(OH)_(2)BDC)with a self-contained organic interface and low conductivity,a composite epoxy coating(2D Co_(2)(OH)_(2)BDC-PAN/EP)was constructed by a two-step preparation.First,a polyacrylonitrile(PAN)nanofiber membrane was electrospuned on the surface of Q235 steel,followed by coating using the epoxy coating(EP)containing 2D Co_(2)(OH)_(2)BDC.The 2D Co_(2)(OH)_(2)BDC-PAN/EP composite epoxy coatings showed robust mechanical performance and excellent corrosion resistance capacity. | Zhao Huarong Zhang Yueshuang Gan Shaojie Yue Qiankun Liu Zan Cheng Zhilin | 2022 | China Petroleum Processing & Petrochemical Technology2022，24，2： | 2 |
| 5 | Displacement of surrounding rock in a deep circular hole considering double moduli and strength-stiffness degradation显示文摘The problem of cavity stability widely exists in deep underground engineering and energy exploitation.First,the stress field of the surrounding rock under the uniform stress field is deduced based on a post-peak strength drop model considering the rock’s characteristics of constant modulus and double moduli.Then,the orthogonal non-associative flow rule is used to establish the displacement of the surrounding rock under constant modulus and double moduli,respectively,considering the stiffness degradation and dilatancy effects in the plastic region and assuming that the elastic strain in the plastic region satisfies the elastic constitutive relationship.Finally,the evolution of the displacement in the surrounding rock is analyzed under the effects of the double modulus characteristics,the strength drop,the stiffness degradation,and the dilatancy.The results show that the displacement solutions of the surrounding rock under constant modulus and double moduli have a unified expression.The coefficients of the expression are related to the stress field of the original rock,the elastic constant of the surrounding rock,the strength parameters,and the dilatancy angle.The strength drop,the stiffness degradation,and the dilatancy effects all have effects on the displacement.The effects can be characterized by quantitative relationships. | Zenghui ZHAO WeiSUN Shaojie CHEN Yuanhui FENG Weiming WANG | 2020 | Applied Mathematics and Mechanics(English Edition)2020，41，12： | 2 |
| 6 | Cross-Layer Framework for Fine-Grained Channel Access in Next Generation High-Density Wi Fi Networks显示文摘Densely deployed Wi Fi networks will play a crucial role in providing the capacity for next generation mobile internet. However, due to increasing interference, overlapped channels in Wi Fi networks and throughput efficiency degradation, densely deployed Wi Fi networks is not a guarantee to obtain higher throughput. An emergent challenge is how to effi ciently utilize scarce spectrum resources, by matching physical layer resources to traffi c demand. In this aspect, access control allocation strategies play a pivotal role but remain too coarse-grained. As a solution, this research proposes a flexible framework for fine-grained channel width adaptation and multi-channel access in Wi Fi networks. This approach, named SFCA(Subcarrier Fine-grained Channel Access), adopts DOFDM(Discontinuous Orthogonal Frequency Division Multiplexing) at the PHY layer. It allocates the frequency resource with a subcarrier granularity, which facilitates the channel width adaptation for multi-channel access and thus brings more fl exibility and higher frequency efficiency. The MAC layer uses a frequencytime domain backoff scheme, which combines the popular time-domain BEB scheme with a frequency-domain backoff to decrease access collision, resulting in higher access probability for the contending nodes. SFCA is compared with FICA(an established access scheme)showing significant outperformance. Finally we present results for next generation 802.11 ac Wi Fi networks. | ZHAO Haitao ZHANG Shaojie Emiliano Garcia-Palacios | 2016 | China Communications2016，13，2： | 2 |
| 7 | Luminescence,Concentration Quenching and Thermal Stability of White Emitting Phosphor Ba_2Ca(BO_3)_2:Dy^(3+)显示文摘A white emitting phosphor Ba2Ca(BO3)2:Dy3+ was synthesized via a high temperature solid state reaction at 1000℃ for 5 h. The luminescence, mole fraction quenching and thermal stability of Ba2Ca(BO3)2:Dy3+ were investigated. According to the phase composition analyzed by X-ray powder diffraction, there is no crystalline phase except Ba2Ca(BO3)2 in the sample. Ba2Ca(BO3)2:Dy3+ can produce white emission under 348 nm excitation. The emission intensities of Ba2Ca(BO3)2:Dy3+ are affected by Dy3+ concentration. The concentration quenching effect was analyzed, and the concentration quenching mechanism was verified as dipole-dipole interaction. The critical distance(R c) obtained based on the crystal structure data is 2.911 nm. At 150℃, the emission intensity of Ba2Ca(BO3)2:Dy3+ is 68.0% of the initial value at room temperature. The activation energy for the thermal quenching calculated is 0.202 e V. Moreover, the CIE chromaticity coordinates of Ba2Ca(BO3)2:Dy3+ locate in the white region of(0.319, 0.356). | SONG Huiling ZHOU Fen CAO Heying GUO Mingchao ZHAO Jiawei WANG Zhijun LIU Haiyan GAO Shaojie LI Panlai | 2015 | Journal of the Chinese Ceramic Society2015，，2： | 1 |
| 8 | High-level expression, purification, and characterization of non-tagged Aspergillus Xavus urate oxidase in Escherichia coli显示文摘 | Li Jianmin Chen Zhao Hou Lihua Fan Hongyan Weng Shaojie Xu Chun'e Ren Jun Li Bing Chen Wei | 2006 | Protein Expression and Purification2006，491，： | 1 |
| 9 | Acoustic Goos-H?nchen effect显示文摘We report two models of the lateral displacement of acoustic-wave scattering on a fluid-solid interface that reveal an acoustic analog of the Goos-H?nchen effect in optics. This acoustic analog is called the acoustic Goos-H?nchen effect. Using newly proposed models, we made numerical calculations for the system of a water-Perspex interface. Specifically, in the post-critical-angle region,we observed a lateral displacement(and transition time) of the reflected P-wave with respect to the incident P-wave. The first arrival of the acoustic signal from the interface is found to be a reflected P-wave rather than the sliding-refraction P-wave usually described in traditional acoustic-logging sliding P-wave theory. For both proposed models, the effective propagation speed of the reflected P-wave along the interface depends on not only the physical properties of the interfacial media but also the incident angle.These observations are intriguing and warrant further investigation. | Lin Fa Ling Xue YuXiao Fa YongLan Han YanDong Zhang HongShen Cheng PengFei Ding GuoHui Li ShaoJie Tang ChunLing Bai BingJie Xi XiaoLin Zhang MeiShan Zhao | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，10： | 1 |
| 10 | Imbalanced Intrahepatic Cytokine Expression of Interferon-γ, Tumor Necrosis Factor-α, and Interleukin-10 in Patients With Acute-on-Chronic Liver Failure Associated With Hepatitis B Virus Infection显示文摘 | Zhengsheng Zou Baosen Li Dongping Xu Zheng Zhang Jing-Min Zhao Guangde Zhou Yanling Sun Lei Huang Junliang Fu Yongping Yang Lei Jin Wei Zhang Jun Zhao Ying Sun Shaojie Xin Fu-Sheng Wang | 2009 | Journal of Clinical Gastroenterology2009，，2： | 1 |
| 11 | Utilizationof steel slag,iron tailings and fly ash as aggregates toprepare a polymer-modified waterproof mortar with a core-shell styrene-acrylic copolymer as the modifier 显示文摘 | Liu Shaojie Hu Qianqian Zhao Fengqing | 2014 | Construction and Building Materials2014，72，： | 1 |
| 12 | Synthesis and Thermal Properties of Three Energetic Ion Salts of 3,6-Bis[(1H-1,2,3,4-tetrazol-5-yl)-amino]- 1,2,4,5-tetr azine显示文摘Three energetic ion salts of 3,6-bis[(1H-1,2,3,4-tetrazol-5-yl)-amino]-1,2,4,5-tetrazine(BTATz), namely, methylamine salt(compound 1), ethylenediamine salt(compound 2), and diethylamine salt(compound 3), were synthesized and characterized by elemental analysis, Fourier transform infrared spectrometry, NMR spectroscopy, and ^13C NMR spectroscopy. The crystal structure of compound 1 was determined by single-crystal X-ray crystallography, and structural analysis revealed that it belonged to the monoclinic system with P21/c space group. In addition, the thermal behavior of the three compounds was studied by differential scanning calorimetry and thermogravimetry techniques. The thermal decomposition peak temperatures of the compounds were 574.89, 545.60, and 606.72 K, indicating that the three ion salts exhibited good thermal stability. Tlie kinetic mechanism equations of the main decomposition process and the entropy of activation(△S^≠), enthalpy of activation(△H^≠), and Gibbs free energy of activation(△G^≠) of the three compounds were also obtained. Moreover, the thermal safety of the compounds was evaluated by the values of the self^accelerated decomposition temperature(Tsadt)5 thermal ignition temperature(TTIT), and critical temperature of thermal explosion(7b). The results showed that all the compounds demonstrated good thermal safety, and the thermal safety of compound 3 was better than that of the others. | ZHOU Jie WU Shaojie ZHANG Wenhui LIU Qmg YANG Bin REN Yinghui MA Haixia ZHAO Fengqi HU Rongzu | 2019 | Chemical Research in Chinese Universities2019，35，3： | 1 |
| 13 | Shear behaviour of anchored jointed rock mass under different engineering conditions considering damage and joint surface morphology显示文摘According to different geological conditions and engineering disturbance,three dimensional numerical models of anchored jointed rock mass with two kinds of boundary conditions of constant normal load(CNL)and constant normal stiffness(CNS)were constructed considering the ductility damage of rockbolt,the stiffness degradation of grouting layer and the joint surface roughness.The effects of anchorage angle,joint surface morphology,and boundary conditions on the shear performance of anchorage system were analyzed,and the failure characteristics under different working conditions were revealed.Finally,the analytical solution of shear strength of anchored system was established.Results show that the larger the anchorage angle is,the more serious the necking phenomenon of rockbolt will be.The damage degree of the bonding layer and the horizontal displacement of the bedding rock mass decrease with the increase of the joint surface roughness.The CNL condition is to instantaneously apply high normal stress,and the CNS condition is to gradually form a high normal stress environment through the superposition of increment on the basis of the initial value,which can resist greater transverse load.This is equivalent to enhancing the ductility of the rockbolt.The shear strength of the system increases with the increase of normal stress and normal stiffness.Ignoring the normal stiffness will underestimate the shear strength. | Zenghui Zhao Wei Sun Shaojie Chen Hao Liu | 2023 | Underground Space2023，，6： | 0 |
| 14 | Development of a UPLC–MS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study显示文摘A simple, rapid and sensitive method based on an ultra-performance liquid chromatography–tandem mass spectrometry(UPLC–MS/MS) has been developed and validated for the determination of pimavanserin in rat plasma. The analyte was extracted by protein precipitation with methanol and separated on an ACQUITY BEH C_(18) column(100 mm × 2.1 mm, 1.7 μm; Waters, USA), with an isocratic elution of acetonitrile-water containing 10 mM ammonium acetate(70:30, v/v), at a flow rate of 0.2 m L/min for 2.5 min. The analyte and clarithromycin(the internal standard) were detected and quantified in positive ion mode using multiple reaction monitoring transitions at m/z 428.2 → 223.0 for pimavanserin and m/z 748.5 → 589.5 for clarithromycin. Relative coefficient(r) for the calibration curve was more than 0.9980. The intra-day and inter-day precisions(relative standard deviation, RSD%) were less than 13.3% and 10.5%, respectively, and the accuracy(relative error, RE%) was within ± 11.5%. The analytical method was successfully applied to a routine pharmacokinetic study of pimavanserin in rats after oral administration at the dose of 10 mg/kg. | Shixiao Wang Yang Wang Shuang Gao Yuanyuan Zhang Hanpei Wang Longshan Zhao Kaishun Bi Shaojie Wang Xiaohui Chen | 2017 | Journal of Pharmaceutical Analysis2017，7，6： | 0 |
| 15 | Morphology and Molecular Identification of Root-knot Nematode in Partial Tobacco-growing Areas in Yunnan Province显示文摘[Objectives]The species and distribution of root-knot nematodes in tobacco growing regions of Yunnan were investigated,in order to provide reference for comprehensive prevention of root-knot nematodes disease and tobacco variety layout. [Methods]Fifty-four samples of root-knot nematode host on tobacco crops were collected from Kunming,Qujing and Yuxi cities in Yunnan from August to October in 2015. The species of root-knot nematodes were identified by observing perineal patterns and molecular biological testing( PCR of ribosomal DNA of ITS region and sequence characterized amplified region,SCAR). [Results] There were 24 samples belonging to Meloidogyne arenaria,accounting for 44. 44%; seven M. incognita samples,accounting for 12. 96%; one M. javanica sample,accounting for 1. 85%. Eleven samples were compound populations of M. javanica and M. arenaria,accounting for 20. 37%. Five were compound populations of M. incognita and M. arenaria,accounting for 9. 26%. Three were compound populations of M. incognita and M. javanica,accounting for 5. 56%. Three belonged to compound population of M. incognita,M. javanica and M. arenaria,accounting for 5. 56%. [Conclusions] The species of root-knot nematodes in tobacco growing areas of Yunnan mainly include M. incognita,M. javanica and M. arenaria. M. arenaria is the dominant population. | Yang Yanmei Liang Yan Yuan Shaojie Zhao Xicheng Hu Xianqi | 2017 | Plant Diseases and Pests2017，8，2： | 0 |
| 16 | Construction of Arabidopsis thaliana ugt84a2/ugt84a4 Double Mutants Mediated by CRISPR/Cas9显示文摘[Objectives]The CRISPR/Cas9(Clustered regulatory interspaced short palindromic repeat/Cas9)gene editing technology is the third generation of'genome fixed-point editing technology'following the'zinc finger endonuclease(ZFN)'and'transcription activator effector nuclease(TALEN)'.Glucotransferase genes UGT84A2 and UGT84A4,can simultaneously convert hydroxycinnamate into 1-O-β-glucose esters as isozymes.The CRISPR/Cas9 technology was used to construct double mutants of Arabidopsis thaliana ugt84a2/ugt84a4.[Methods]A CRISPR/Cas9 double mutant expression vector was constructed using UGT84A2 and UGT84A4 as the target genes.The Agrobacterium-mediated dip dyeing method was used to transform wild-type A.thaliana,and the CRISPR/Cas9system was used to target and knock out A.thaliana UGT84A2 and UGT84A4 genes.[Results]The descendants of A.thaliana with the UGT84A2/UGT84A4 gene were sequenced and analyzed.Thirteen positively transformed plants obtained were analyzed according to the sequencing results,and the ugt84a2/ugt84a4 double mutants were screened.[Conclusions]This study provides a reference for the functional study of UGT84A2 and UGT84A4 isoenzyme genes in other species,as well as strong theoretical and method support for accelerating the development and utilization of UGT84A2/UGT84A4 functional gene resources. | Xiumei GONG Xuelin WU Kaixuan ZHOU Wei ZHAO Yuanyuan SUN Shaojie SANG Guizhi ZHANG Jundong HE | 2022 | Agricultural Biotechnology2022，11，4： | 0 |
| 17 | Xingshentongqiao Decoction Mediates Proliferation, Apoptosis, Orexin-A Receptor and Orexin-B Receptor Messenger Ribonucleic Acid Expression and Represses Mitogen-activated Protein Kinase Signaling显示文摘 | Yuanli Dong Mei Li Shaojie Wang Yuwei Dong Hongxia Zhao Zhong Dai | 2015 | Chinese Medical Journal2015，，1： | 0 |
| 18 | Assessing Landsat-8 atmospheric correction schemes in low to moderate turbidity waters from a global perspective显示文摘Atmospheric correction is one of the major challenges in ocean color remote sensing,thus threatening comprehensive evaluation of water quality within aquatic environments.In this study,five state-of-the-art atmospheric correction(AC)processors(i.e.Acolite,C2RCC,iCOR,L2gen,and Polymer)were applied to Operational Land Imager(OLI)Landsat-8 scenes and evaluated against in situ measurements across various types of waters worldwide.A total of 262 matchups between in situ measured and satellite-derived remote sensing reflectance(R_(rs))at 20 sites were obtained between August 2013 and August 2021.Classification of optical water types(OWTs)was carried out using in situ measurements with matched satellite observations.OWT-specific analysis demonstrated that L2gen produced the most accurate Rrs with R^(2)≥0.74 and root mean squared error(RMSE)≤0.0018 sr^(–1) for the four visible bands of OLI,followed by Polymer,C2RCC,iCOR,and Acolite.In terms of R_(rs) spectral similarity,C2RCC yielded the lowest spectral angle(SA)of 8.55°,followed by L2gen(SA=9.20°).The advantage and disadvantage of each AC scheme were discussed.Recommendations to improve the accuracy for atmospheric correction were made,such as polarization observations and concurrent aerosol and ocean color measurements. | Nanyang Yan Zhen Sun Wei Huang Zhao Jun Shaojie Sun | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
| 19 | Clinical Study of Endovascular Treatment of Severe Middle Cerebral Artery Stenosis or Occlusion and Vascular Cognitive Impairment显示文摘It is very important to study the factors affecting the incidence,progress and prognosis of patients with vascular dementia.50 cases of severe middle cerebral artery stenosis or occlusion underwent endovascular treatment(25 cases of mild cognitive dysfunction,25 cases of moderate cognitive dysfunction)were divided into two groups,where a medical drug treatment group and a control group established with 25 cases in each group.The cognitive function of each group of patients was evaluated before operation,7 days after operation,30 days after operation,and 180 days after operation.CTP was used to compare the hemodynamic changes in patients before and after operation.The severe stenosis or occlusion of the middle cerebral artery in patients can be improved,and the intracranial blood supply of patients with poorly compensated medial cranial circulation and hypoperfusion can be restored to a certain extent.Meanwhile,improvement of cognitive function was definitive in some patients with cognitive dysfunction.To guide the formulation of treatment plans for patients with severe middle cerebral artery stenosis or occlusion. | Shaojie Yuan Tong Zhang Xiaohui Zhao Liying Yuan Dan Wang | 2021 | Journal of Advances in Medicine Science2021，4，2： | 0 |
| 20 | Effects of external dynamic disturbances and structural plane on rock fracturing around deep underground cavern显示文摘The occurrence of disasters in deep mining engineering has been confirmed to be closely related to the external dynamic disturbances and geological discontinuities.Thus,a combined finite-element method was employed to simulate the failure process of an underground cavern,which provided insights into the failure mechanism of deep hard rock affected by factors such as the dynamic stress-wave amplitudes,disturbance direction,and dip angles of the structural plane.The crack-propagation process,stress-field distribution,displacement,velocity of failed rock,and failure zone around the circular cavern were analyzed to identify the dynamic response and failure properties of the underground structures.The simulation results indicate that the dynamic disturbance direction had less influence on the dynamic response for the constant in situ stress state,while the failure intensity and damage range around the cavern always exhibited a monotonically increasing trend with an increase in the dynamic load.The crack distribution around the circular cavern exhibited an asymmetric pattern,possibly owing to the stress-wave reflection behavior and attenuation effect along the propagation route.Geological discontinuities significantly affected the stability of nearby caverns subjected to dynamic disturbances,during which the failure intensity exhibited the pattern of an initial increase followed by a decrease with an increase in the dip angle of the structural plane.Additionally,the dynamic disturbance direction led to variations in the crack distribution for specific structural planes and stress states.These results indicate that the failure behavior should be the integrated response of the excavation unloading effect,geological conditions,and external dynamic disturbances. | Fan Feng Shaojie Chen Xingdong Zhao Diyuan Li Xianlai Wang Jiqiang Cui | 2022 | International Journal of Coal Science & Technology2022，9，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员