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202篇 您的检索式：作者名="Settleman"

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	题名	作者	年代	出处	被引量
1	癌症启动中Kras的特异性功能显示文摘三种密切相关的Ras蛋白,即Kras、Hras和Nras构成了小分子GTP酶的Ras超家族成员,它们可以作为分子开关,传递细胞外信号从而引发一系列基本的细胞过程.包括增殖、存活和分化。癌症生物学家发现在人类肿瘤细胞中,编码这些蛋白的基因突变率较高。大约30%的人类肿瘤细胞中出现Ras基因突变,也有一系列参与Ras途径的基因发生突变。由于GTP水解作用可灭活蛋白,因此RasGTP酶信号转导通常具有自限性,	Margaret P. Quinlan Jeffrey Settleman	2008	癌症2008，27，7：	8
2	A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations显示文摘	Sreenath V. Sharma Diana Y. Lee Bihua Li Margaret P. Quinlan Fumiyuki Takahashi Shyamala Maheswaran Ultan McDermott Nancy Azizian Lee Zou Michael A. Fischbach Kwok-Kin Wong Kathleyn Brandstetter Ben Wittner Sridhar Ramaswamy Marie Classon Jeff Settleman	2010	Cell2010，，1：	2
3	EMT,cancer stem cells and drug resistance:an emerging axis of evil in the war on cancer显示文摘	Singh A Settleman J		0，，34：	1
4	The Rho-GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation 显示文摘	Barrett K Leptin M Settleman J	1997	Cell1997，91，7：	1
5	Oncogene addiction:setting the stage for molec-ularly targeted cancer therapy显示文摘	Sharma SV Settleman J	2007	Genes Dev2007，21，24：	1
6	The complexity of targeting EGFR signalling in cancer: from expression to turnover显示文摘	SEBASTIAN S SETTLEMAN J RESHKIN SJ	2006	Biochim Biophys Acta2006，1766，1：	1
7	Personalized cancer therapy with selective kinase inhibitors:an emerging paradigm in medical oncology显示文摘	McDermott U Settleman J	2009	J ClinOncol2009，27，：	1
8	EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer显示文摘	Singh A Settleman J	2010	Oncogene2010，29，34：	1
9	EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer 显示文摘	Singh A Settleman J	2010	Oncogene2010，29，34：	1
10	Epidermal growth factor receptor mutations in lung cancer 显示文摘	Sharma SV Bell DW Settleman J	2007	Nature Rev Cancer2007，7，3：	1
11	Epidermal growth factor receptor mutations in lung cancer显示文摘	Sharma SV Bell DW Settleman J	2007	Nat Rev Cancer2007，7，3：	1
12	Epidermal growth factor receptor mutations in lung cancer显示文摘	Sharma S V Bell D W Settleman J	2007	Nat Rev Cancer2007，7，3：	1
13	Epidermal growth factor receptor mutations in lung cancer显示文摘	Sharma SV Bell DW Settleman J		0，，03：	1
14	Epidermal growth factor receptor mutations in lung cancer 显示文摘	Sharma SV Bell DW Settleman J	2007	Nat Rev Cancer2007，7，3：	1
15	The Complexity of Targe- ting EGFR Signalling in Cancer :from Expression to Turnover 显示文摘	Sebastian S Settleman J Reshkin S J	2006	Biochim Biophys Acta2006，1766，1：	1
16	EMT, cancer stem cells and drug resist- ance: an emerging axis of evil in the war on cancer 显示文摘	Singh A Settleman J	2010	Onco- gene2010，29，34：	1
17	Epidermal growth factor receptor mutations in lung cancer显示文摘	Sharma SV Bell DW Settleman J	2007	Nat Rev Cancer2007，7，3：	1
18	Epidermal growth fac-tor receptor mutations in lung cancer显示文摘	Bell DW Settleman J	2007	Nat Rev cancer2007，7，：	1
19	Epidermal growth factor receptor mutations in lung cancer显示文摘	Sharma SV Bell DW Settleman J	2007	Nat Rev Cancer2007，7，3：	1
20	Oncogene addiction:setting the stage for molecularly targeted cancer therapy显示文摘	Sharma SV Settleman J	2007	Genes Dev2007，21，24：	1

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