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| 1 | Changing trends in the mortality rate at 1-year post hip fracture-a systematic review显示文摘BACKGROUND Traditionally, the mortality rate at 1-year post hip fracture was quoted as approximately 30% of all hip fractures. There have been recent improvements in hip fracture care in the main driven by national hip fracture registries with reductions in 30-d mortality rates reported.AIM To address recent 1-year post hip fracture mortality rates in the literature.METHODS Systematic literature review, national hip fracture registries/databases, local studies on hip fracture mortality, 5 years limitation(2013-2017), cohorts > 100,studies in English. Outcome measure: Mortality rate at 1-year post hip fracture.RESULTS Recent 1-year mortality rates were reviewed using the literature from 8 National Registries and 36 different countries. Recently published 1-year mortality rates appear lower than traditional figures and may represent a downward trend.CONCLUSION There appears to be a consistent worldwide reduction in mortality at 1-year post hip fracture compared to previously published research. Globally, those which suffer hip fractures may currently be benefiting from the results of approximately 30 years of national registries, rigorous audit processes and international collaboration. The previously quoted mortality rates of 10% at 1-mo and 30% at 1-year may be outdated. | Colum Downey Martin Kelly John F Quinlan | 2019 | World Journal of Orthopedics2019，10，3： | 17 |
| 2 | Induction of decision trees显示文摘 | J. R. Quinlan | 1986 | Machine Learning1986，，1： | 13 |
| 3 | 癌症启动中Kras的特异性功能显示文摘三种密切相关的Ras蛋白,即Kras、Hras和Nras构成了小分子GTP酶的Ras超家族成员,它们可以作为分子开关,传递细胞外信号从而引发一系列基本的细胞过程.包括增殖、存活和分化。癌症生物学家发现在人类肿瘤细胞中,编码这些蛋白的基因突变率较高。大约30%的人类肿瘤细胞中出现Ras基因突变,也有一系列参与Ras途径的基因发生突变。由于GTP水解作用可灭活蛋白,因此RasGTP酶信号转导通常具有自限性, | Margaret P. Quinlan Jeffrey Settleman | 2008 | 癌症2008，27，7： | 8 |
| 4 | Cost benefit analysis of the use of tranexamic acid in primary lower limb arthroplasty: A retrospective cohort study显示文摘AIM: To examine the cost benefit conferred by the perioperative administration of intravenous tranexamic acid(TXA) in lower limb arthroplasty.METHODS: This study evaluates the use of TXA in 200 consecutive lower limb arthroplasties performed in a single surgeon series. The initial 100 patients(control group) underwent surgery without perioperative administration of TXA while the subsequent 100 patients(TXA group) all received 1 g TXA at the time of induction of anaesthesia. Pre- and post-operative haemoglobin, platelet count, haematocrit, the use of blood product post-operatively, length of stay were examined. A financial analysis of both groups was then undertaken. RESULTS: The mean age of patients in both groups was 63 ± 13 years. There were no significant differences between groups in terms of gender(P = 0.47), proportion of total hip replacement to total knee replacement(P = 0.25) or pre-operative haemoglobin(P = 0.43). In the control group, the transfusion rate was 22%. In the TXA group, the transfusion rate dropped to 2%(P < 0.001). The mean post-operative haemoglobin was 10.82 ± 1.55g/dL in the control group vs 11.33 ± 1.27 g/dL in the TXA group(P = 0.01). The total cost of transfused blood products was €11055 and €603 respectively. The mean length of stay in the control group was 6.53 ± 5.93 d vs 5.47 ± 4.26 d in the TXA group(P = 0.15) leading to an estimated financial saving of €114586. There was one pulmonary embolus in the control group and one deep venous thrombosis in the TXA group.CONCLUSION: Intravenous TXA reduces blood loss in lower limb arthroplasty. This leads to lower transfusion rates, shorter length of stay in hospital and significant financial savings. | Niall P McGoldrick Eabhann M O'Connor Nikos Davarinos Rose Galvin John F Quinlan | 2015 | World Journal of Orthopedics2015，6，11： | 3 |
| 5 | Induction of decision trees显示文摘 | J. R. Quinlan | 1986 | Machine Learning1986，，1： | 3 |
| 6 | Simplifying decision trees显示文摘 | QUINLAN J R | 1987 | Int J Man-Mach Stud1987，27，： | 2 |
| 7 | Decision trees and decision making显示文摘 | Quinlan J R | 1990 | IEEE Transactions on Systems Man and Cybernetics1990，20，2： | 2 |
| 8 | A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations显示文摘 | Sreenath V. Sharma Diana Y. Lee Bihua Li Margaret P. Quinlan Fumiyuki Takahashi Shyamala Maheswaran Ultan McDermott Nancy Azizian Lee Zou Michael A. Fischbach Kwok-Kin Wong Kathleyn Brandstetter Ben Wittner Sridhar Ramaswamy Marie Classon Jeff Settleman | 2010 | Cell2010，，1： | 2 |
| 9 | Induction of decision trees显示文摘 | Quinlan J R | 1986 | Machine Learning1986，1，1： | 2 |
| 10 | Induction of logic programs: FOIL and related systems显示文摘 | Quinlan J R Cameron-Jones R M | 1995 | New Generation Computing1995，13，34： | 2 |
| 11 | Induction of Decision Trees显示文摘 | Quinlan 3 R | 1986 | Machine Learning1986，，01： | 1 |
| 12 | Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma 显示文摘 | Xu H J Quinlan D C Davidson A G | 1994 | J Natl Cancer Inst1994，86，9： | 1 |
| 13 | Induction of decision trees显示文摘 | Quinlan J R | 1986 | Machine Learning1986，，： | 1 |
| 14 | Induction of decision tree显示文摘 | Quinlan J R | 1986 | Machine Learning1986，1，1： | 1 |
| 15 | The effect of repeated exposure to particulate air pollution (PM10) on the bone marrow显示文摘 | MUKAE H VINCENT R QUINLAN K | 2001 | Am J Respir Crit Care Med2001，163，： | 1 |
| 16 | Extended-duration prophylaxis against venous thromboembolism after total hip or knee replacement:a meta anlysis of the randomized trials显示文摘 | Eikel boom JW Quinlan DJ Douketis JD | 2001 | Lancet2001，358，： | 1 |
| 17 | Cardioprotective signaling to mitochondria显示文摘 | Garlid KD Costa AD Quinlan CL | 2009 | J Mol Cell Cardiol2009，46，6： | 1 |
| 18 | Inter- and in- tra-observer variability associated with the use of the Mirels' sco- ring system for metastatic bone lesions 显示文摘 | Mac Nioeaill RF Quinlan JF Stapleton RD | 2011 | Int Orthop2011，35，1： | 1 |
| 19 | A molecular mechanism for stabilization of learning-induced synaptic modifications显示文摘 | QUINLAN E M LEBEL D BROSH I | 2004 | Neuron2004，41，： | 1 |
| 20 | The relationship between stool hardness and stool composition in breast-and formula-fed infants显示文摘 | Quinlan PT Lockton S Irwin J | 1995 | J Pediatr Gastroenterol Nutr1995，，： | 1 |
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