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| 1 | Antiviral innate immunity pathways显示文摘最近的研究揭开了激活主人的二个发信号小径对病毒的感染的天生的免疫。小径之一利用像使用费的受体(TLR ) 的成员检测通过 endocytosis 进入内涵体的病毒的家庭。TLR 小径通过最终导致抄写因素 NF-kappaB, IRF3 和 IRF7 的激活的几发信号的蛋白质导致干扰素生产。另外的抗病毒的小径为细胞内部的病毒的双 stranded RNA 把 RNA helicase RIG-I 用作受体。RIG-I 通过最近识别的适配器蛋白质 MAVS 激活 NF-kappaB 和 IRF,包含居住在 mitochondrial 膜的蛋白质的一个卡片领域。MAVS 为抗病毒的天生的免疫是必要的,但是它也用作丙肝病毒(HCV ) 的一个目标,它采用病毒的朊酶劈开 MAVS 离开线粒体,从而允许 HCV 逃离主人免疫系统。 | Rashu B Seth Lijun Sun Zhijian J Chen | 2006 | Cell Research2006，16，2： | 45 |
| 2 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 3 | Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern,the greater sage-grouse,in humanaltered environments显示文摘Introduction:Ground-nesting birds experience high levels of nest predation.However,birds can make selection decisions related to nest site location and characteristics that may result in physical,visual,and olfactory impediments to predators.Methods:We studied daily survival rate[DSR]of greater sage-grouse(Centrocercus urophasianus)from 2008 to 2010 in an area in Wyoming experiencing large-scale alterations to the landscape.We used generalized linear mixed models to model fixed and random effects,and a correlation within nesting attempts,individual birds,and years.Results:Predation of the nest was the most common source of nest failure(84.7%)followed by direct predation of the female(13.6%).Generally,landscape variables at the nest site(≤30 m)were more influential on DSR of nests than features at larger spatial scales.Percentage of shrub canopy cover at the nest site(15-m scale)and distances to natural gas wells and mesic areas had a positive relationship with DSR of nests,whereas distance to roads had a negative relationship with DSR of nests.When added to the vegetation model,maximum wind speed on the day of nest failure and a 1-day lag in precipitation(i.e.,precipitation the day before failure)improved model fit whereby both variables negatively influenced DSR of nests.Conclusions:Nest site characteristics that reduce visibility(i.e.,shrub canopy cover)have the potential to reduce depredation,whereas anthropogenic(i.e.,distance to wells)and mesic landscape features appear to facilitate depredation.Last,predators may be more efficient at locating nests under certain weather conditions(i.e.,high winds and moisture). | Stephen L Webb Chad V Olson Matthew R Dzialak Seth M Harju Jeffrey B Winstead Dusty Lockman | 2012 | Ecological Processes2012，1，1： | 2 |
| 4 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 5 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 6 | Percutaneous intracoronary cellular cardiomyoplasty for nonischemic cardiomyopathy:clinical and histopathological results:the first-in-man ABCD (Autologous Bone Marrow Cells in Dilated Cardiomyopathy) trial显示文摘 | Seth S Narang R Bhargava B | | 0，，11： | 1 |
| 7 | Replacing asbestos steam path gaskets显示文摘 | Jones W F Seth B | 1993 | Power Engineering1993，96，3： | 1 |
| 8 | Influence of surfactants treatment on silver powder and its thick films 显示文摘 | RANE S B SETH T PHATAK G J | 2003 | Mater Lett2003，57，20： | 1 |
| 9 | Multivariate granger causality and generalized variance显示文摘 | Barrett A B Barnett L Seth A K | 2010 | Physical Review E2010，81，04： | 1 |
| 10 | Damage mechanics approach for bearing lifetime prognostics显示文摘 | Qiu J Zhang C Seth B B Liang S Y | 2002 | Mechanical Systems and Signal Processing2002，16，5： | 1 |
| 11 | Biochemical effects of some pesticides on lipid peroxidation and free- radical scavengers显示文摘 | BANERJEE B D SETH V BHATTACHARYA A | 1999 | Toxicology Letters1999，107，： | 1 |
| 12 | Pigmentary Disorders 显示文摘 | JEAN L B SETH J O | 2000 | Melanotype Biology2000，，1： | 1 |
| 13 | Effect of inorganic binders on the properties of silver thick films 显示文摘 | RANE S B SETH T PHATAK G J | 2004 | J Mater Sci: Mater Electron2004，15，： | 1 |
| 14 | Effect of inorganic binders on the properties of silver thick films显示文摘 | Rane S B Seth T Phatak G J | 2004 | Materials in Electronics2004，15，： | 1 |
| 15 | Efficacy of postoperative patient - controlled and continuous ifusion epidural analgesia versus intravenous patient controlled analgesia with opioi- da 显示文摘 | CHRISTOPHER L W SETH R COHEN B C | 2005 | Anrsthesiology2005，103，6： | 1 |
| 16 | Flavonoids from the flowers of Clerodendron infortunatum 显示文摘 | Sinha N K Seth K K Pandey V B | 1981 | Planta Med1981，42，： | 1 |
| 17 | How normal is'normal'? mild tremor in a multiethnic cohort of normal subject 显示文摘 | LOUIS ED FORD B SETH P | 1998 | Arch Neurol1998，55，： | 1 |
| 18 | Stages of em- bryonic development of the Zebrafish显示文摘 | Charles B K William W B Seth R K | 1995 | Dev Dyn1995，203，： | 1 |
| 19 | Biochemical effects of some pesticides on lipid peroxidation and free-radical scavengers显示文摘 | BANERJEE B D SETH V BHATTARYA A | | 0，，： | 1 |
| 20 | Monitoring of black tea fermentation process using electronic nose显示文摘 | Bhattacharyya N Seth S Tudu B | 2007 | Joumal of Food Engineering2007，80，4： | 1 |
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