|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 活性氧在柠檬醛抑制黄曲霉产毒过程中的作用显示文摘为探究ROS在柠檬醛抑制黄曲霉产毒过程中的作用,对柠檬醛作用下黄曲霉细胞释放ROS的含量、胞内ROS水平、抗氧化酶类活性和细胞氧化损伤程度的变化进行监测。结果表明,柠檬醛会使黄曲霉细胞内ROS含量明显增多,并部分释放到胞外。与甘油处理组相比,柠檬醛处理组的黄曲霉毒素含量明显较低,柠檬醛作用下的黄曲霉胞内抗氧化酶(CAT、SOD和GSH-Px)活性明显增强,胞内MDA和蛋白质羰基含量明显增大。扫描电镜观察发现,柠檬醛处理组的细胞损伤程度明显高于甘油处理组。综上,黄曲霉在柠檬醛作用下产生ROS,造成黄曲霉氧化损伤,从而抑制黄曲霉毒素的产生。本研究结果对粮食仓储具有一定理论指导意义。 | 李金寒 商博 梁丹丹 Jonathan Nimal Selvaraj 鲁志松 刘阳 | 2016 | 核农学报2016，30，7： | 11 |
| 2 | Groundwater Potential Zoning in Thirumanimuttar Sub-Basin Tamilnadu, India—A GIS and Remote Sensing Approach显示文摘The main objective of the study is to identify groundwater potential zones in Thirumanimuttar basin with an integrated approach using Remote Sensing and geographical information system(GIS).FCC Image of Landsat TM 30 m resolution data and topographic maps has been used to generate thematic maps like geology,geomorphology,lineament and lineament density,drain-age,drainage density,and slope map of the study area.A number of geomorphic units such as Denudational hills,structural hills,Bajadas,Colluvial plain,Pediplain,Deep Pediment and Alluvial plains have been observed.A composite groundwater potential map has been generated as very high,high,medium,low and very low based on the groundwater availability area.The upper,mid-dle and downstream of the basins have been identified as potential zones for groundwater exploration.The regions of lineaments and intersecting lineaments proved for groundwater potential zones.The data generated was validated with field checks and ob-served to be in conformity with the same. | MURUGESAN Vasanthavigar KRISHNARAJ Srinivasamoorthy KANNUSAMY Vijayaragavan SELVARAJ Gopinath SUBRAMANYA Sarma | 2011 | Geo-Spatial Information Science2011，14，1： | 10 |
| 3 | 储存寿命超过2000小时的高功率双面钙钛矿太阳能电池显示文摘有机-无机杂化钙钛矿太阳能电池自问世以来,因其光电转换效率迅速提升得到全球的广泛关注.目前,其光电转换效率已高达25.2%.为实现实际应用,提高其稳定性已成为该领域最为关键的问题.本文作者进行了室温磁控溅射ITO的技术研究,成功利用ITO代替钙钛矿太阳能电池的金属顶电极,其制备的半透明电池光电转换效率可达16.7%.最重要的是其在手套箱中储存2000小时以上,电池效率无任何衰减.此外,研究人员发现该半透明太阳能电池具有非常高的双面电池的应用前景,通过改变电池背电极后的反射介质可成功将其输出功率提高至20 m W/cm^2.最后文章指出目前室温下制备的ITO仍然存在透射率低的问题,随着该技术的进一步优化,不断提高其透过率,其双面光伏特性可得到大幅提高.届时,该类电池也将在光伏建筑一体化应用中崭露头角. | 程远航 谢晨超 刘希夏 朱光耀 李皓华 Selvaraj Venkataraj Zhi-Kuang Tan 丁黎明 Armin Gerhard Aberle 林棻 | 2020 | Science Bulletin2020，65，8： | 7 |
| 4 | Mycotoxin detection——Recent trends at global level显示文摘Mycotoxin contamination in agro-food systems has been a serious concern globally during the last few decades. Mycotoxins are toxic secondary metabolites produced by fungi when they grow in agro-food products and feedstuff. Several detection techniques have been developed in recent years to detect mycotoxins in the food and feed effectively. HPLC based techniques are very common in usage in the laboratories for the testing of mycotoxins. In recent years,immuno-based assays is widely used and have been reported at large due to its sensitivity and limited detection time. Immuno assay-based kits were developed effectively to be used in the fields and in storage systems to detect the mycotoxin levels. Microarray-based immunoassays developed in the recent years could simultaneously detect aflatoxin,ochratoxin,and zearalenone with the higher sensitivity. Aptamer-based assays could target the detection of ochratoxin and aflatoxins and fumonisins at high specificity in food products. In recent years,several assays reported for the simultaneous multiple detection of different mycotoxin was based on HPLC and LC-MS/MS. There is a need for the use of these advanced technologies in the commercial scale. | Jonathan Nimal Selvaraj ZHOU Lu WANG Yan ZHAO Yue-ju XING Fu-guo DAI Xiao-feng LIU Yang | 2015 | Journal of Integrative Agriculture2015，14，11： | 6 |
| 5 | Nanotechnologies in Food Science:Applications,Recent Trends,and Future Perspectives显示文摘Nanotechnology is a key advanced technology enabling contribution,development,and sustainable impact on food,medicine,and agriculture sectors.Nanomaterials have potential to lead qualitative and quantitative production of healthier,safer,and high-quality functional foods which are perishable or semi-perishable in nature.Nanotechnologies are superior than conventional food processing technologies with increased shelf life of food products,preventing contamination,and production of enhanced food quality.This comprehensive review on nanotechnologies for functional food development describes the current trends and future perspectives of advanced nanomaterials in food sector considering processing,packaging,security,and storage.Applications of nanotechnologies enhance the food bioavailability,taste,texture,and consistency,achieved through modification of particle size,possible cluster formation,and surface charge of food nanomaterials.In addition,the nanodelivery-mediated nutraceuticals,synergistic action of nanomaterials in food protection,and the application of nanosensors in smart food packaging for monitoring the quality of the stored foods and the common methods employed for assessing the impact of nanomaterials in biological systems are also discussed. | Shivraj Hariram Nile Venkidasamy Baskar Dhivya Selvaraj Arti Nile Jianbo Xiao Guoyin Kai | 2020 | Nano-Micro Letters2020，12，3： | 6 |
| 6 | Evaluation of wound healing and antimicrobial potentials of Ixora coccinea root extract显示文摘Objective:To evaluate the wound healing and antimicrobial activity of root extracts of Ixora coccinea(I.coccinea).Methods:To investigate the wound healing efficacy of root extract of I.coccinea Linn,five groups of animals were divided each containing six animals.Two wound models including incision and excision wound models were used in this study.The parameters studied were tensile strength on incision wound model and in terms of wound contraction for excision wound model were compared with standard Nitrofurazone(NFZ) ointment(0.2%w/w). Six extracts(ethanol.aqueous,petroleum ether,benzene,chloroform and ethyl acetate ) of I. coccinea were screened for in vitro growth inhibiting activity against different bacterial strains riz. Staphylococcia aureus.Bacillus pumilius,Enterococcus facialis.Escherichia coli,Salmonella typhi and Pseudomonas aeruginosa and fungi Candida albicans and Aspergillus niger were compared with the standard drugs ciprofloxacin and chloramphenicol for antibacterial and griscofulvin for antifungal screening.The serial dilution and cup(or) well plate methods were used for the antimicrobial study and MIC was determined.Results:The ethanolic extract showed significant (P<0.001) wound healing activity when compared to standard drug NFZ with respect to normal control group.Amongst all.ethanolic extract showed highly significant antibacterial activity against all bacterial strains used in this study when compared to standard.The aqueous extract showed moderate significant inhibition against all bacterial strains when compared to standard. All the extracts were shown negligible activity against the fungal strains used in this study. Conclusions:The ethanolic root extract of I.coccinea showed pronounced wound healing and antibacterial activity.The probable reason to heal the wound was that the external application of the extract prevented the microbes to invade through the wound thus the protection of wound occurs against the infection of the various organisms. | Nagaraj Selvaraj Baskar Lakshmanan Papiya Mitra Mazumder Muthukumar Karuppasamy Simon Santosh Jena Ashok Kumar Pattnaik | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，12： | 5 |
| 7 | 花状硫化铟纳米多级结构的液相合成及形貌调控机理显示文摘以C2H5NS和In(NO3)3为前驱物,采用简单的液相法成功制备了In2S3纳米多级结构,C2H5NS作为硫源的同时也起到了模板剂的作用.研究结果表明,前驱物浓度对In2S3形貌控制起着重要作用.随着In(NO3)3/C2H5NS摩尔比从1∶1.5增加到1∶6,In2S3纳米花呈现了不同的形貌和尺寸.XRD谱图显示,In2S3纳米花晶体具有立方结构.SEM和TEM照片显示,制备的In2S3纳米结构呈多级花状结构,这种结构由纳米片堆积组装而成.通过第一性原理计算并结合实验结果对C2H5NS影响纳米片生长的机理进行了分析,结果表明C2H5NS在In2S3(001)晶面上的吸附可以有效降低晶面的表面能,起到稳定晶面的作用;纳米花的形成是在C2H5NS影响In2S3的晶面稳定性及其成核速率之间的一个协同效应.In2S3纳米晶的形貌可以通过调整反应溶液中的C2H5NS浓度来调节. | 戚克振 王艳 付嘉琦 Rengaraj Selvaraj 王贵昌 | 2014 | 高等学校化学学报2014，35，12： | 5 |
| 8 | A Distributed Mechanism for Handling of Adaptive/Intelligent Selfish Misbehaviour at MAC Layer in Mobile Ad Hoc Networks显示文摘Medium access control(MAC) protocols such as IEEE 802.11 are used in wireless networks for sharing of the wireless medium.The random nature of the protocol operation together with the inherent difficulty of monitoring in the open poses significant challenges.All nodes are expected to comply with the protocol rules.But,some nodes in order to gain greater benefits misbehave by not complying with the rules.One such selfish misbehavior is waiting for smaller back-off intervals when compared to the other nodes in the same subnet.Such selfish misbehavior is being tackled in this paper.A diagnosis scheme and a penalty scheme are being proposed for overcoming such selfish-misbehavior at MAC layer of mobile ad hoc networks which could be extended to other types of networks also. | Raja Gunasekaran Vaidheyanathan Rhymend Uthariaraj Uamapathy Yamini Rajagopalan Sudharsan Selvaraj Sujitha Priyadarshini | 2009 | Journal of Computer Science & Technology2009，24，3： | 4 |
| 9 | Kinetics of Atmospheric Corrosion of Mild Steel in Marine and Rural Environments显示文摘在执行更新印度的腐蚀地图的广泛的研究的继续,在这研究,低碳钢的降级坐飞机,污染物质沿着 Tamilnadu 的东方海岸从 Nagore 在 16 个不同地点被学习到 Ammanichatram,在二年的一个时期上的印度。重量损失学习证明低碳钢腐蚀是在 Nagapattinam 地点的更多,当时与 Ammanichatram 和 Maravakadu 地点相比。试验性的数据的线性回归分析被尝试预言腐蚀的机制。在低碳钢表面上形成的腐蚀产品的作文被 XRD 技术识别。获得的腐蚀率价值根据捱过的参数被讨论,大气的污染物质象盐内容那样与那么 < 潜水艇 class= “ a-plus-plus ” > 在空气的 2 个 层次,在低碳钢表面上形成的腐蚀产品。 | S. Palraj M. Selvaraj K. Maruthan M. Natesan | 2015 | Journal of Marine Science and Application2015，14，1： | 4 |
| 10 | Biological activities of Solanum pseudocapsicum(Solanaceae)against cotton bollworm,Helicoverpa armigera Hübner and armyworm,Spodoptera litura Fabricius(Lepidotera:Noctuidae)显示文摘Objective:To evaluate the antifeedant,insecticidal and growth inhibition activities of Solanum pseudocapsicum(S.pseudocapsicum)seed extracts against Spodoptera litura(S.litura)and Helicotverpa armigera(H.armigera).Methods:Hcxane,diethyl cther,dichloromethanc and ethyl acetate seed extracts were prepared and tested for autifeedant,insecticidal and growth inhibitory activities against fourth instar larvae of&litura and H.armigera.Results:Ethyl acetate extract showed promising antifeedant and insecticidal activities against S.litura and H.armigera.Percentage of deformed larvae,pupae and adults were maximum in treatment of ethyl acetate extract.Percentage of successful adult emergence was deteriorated by seeds on extract treated larvae.Conclusions:Ethyl acetate extracts of S.pseudocapsicum,showed higher efficiency of antifeedant,insecticidal and growth inhibition activities.Hence,it can be used to controll agricultural insect pests,S.litura and H.armigera. | Alagarmalai Jeyasankar Selvaraj Premalatha Kuppusamy Elumalai | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，12： | 4 |
| 11 | Increased plasma malondialdehyde and fructosamine in anemic H pylori infected patients:Effect of treatment显示文摘AIM: To unravel the possible association of malon-dialdehyde (MDA) and fructosamine in anemic H pylori infected patients and to observe the alteration in MDA and fructosamine levels in these patients after treatment for one month.METHODS: Fructosamine, MDA and glucose were estimated in 22 anemic H pylori infected patients and 16 healthy controls. Hematological parameters were also evaluated in both the groups using Sysmex-K-100 automated cell counter. The H pylori infected patients were randomly divided into two groups. H pylori infected patients in GroupⅠreceived both iron supplementation and anti-H pylori therapy, while patients in Group Ⅱ received only iron supplementation. All the biochemical and hematological parameters were estimated after one month of treatment. RESULTS: In anemic H pylori infected patients, while MDA (5.41 ± 2.16 vs 2.26 ± 0.50; P < 0.05) and fructosamine (2.64 ± 0.93 vs 1.60 ± 0.35; P < 0.05) were significantly increased, iron (32.72 ± 14.93 vs 110.25 ± 26.58; P < 0.05), hemoglobin (6.9 ± 2.6 vs 12.66 ± 0.74; P < 0.05) and ferritin (28.82 ± 16.27 vs 140.43 ± 30.72; P < 0.05) levels were significantly decreased compared with the controls. With partial correlation analysis, fructosamine was found to have a significant positive correlation with MDA. In GroupⅠ, while MDA level decreased significantly (3.11 ± 1.73 vs 5.50 ± 2.46; P < 0.05), there was a significant increase in iron (84.09 ± 29.51 vs 36.09 ± 17.81; P < 0.05), hemoglobin (10.40 ± 1.11 vs 7.42 ± 1.90; P < 0.05) and ferritin (116.91 ± 63.34 vs 30.46 ± 17.81; P < 0.05) levels after one month. There was no significant change in the levels of fructosamine in groupⅠafter treatment. Similarly, no significant alterations were noted in the levels of MDA, fructosamine, hemoglobin or ferritin in Group Ⅱ patients after one month of treatment.CONCLUSION: An increased level of fructosamine and MDA was found in anemic H pylori infected patients. Present data supports the premise that lipid peroxides per se do play a role in the glycation of plasma proteins. Furthermore, the findings from this study indicate that treatment for both anemia and H pylori infections is required for lowering the levels of lipid peroxides in these patients. | G Vijayan RC Sundaram Zachariah Bobby Abdoul Hamide N Selvaraj N Rattina Dasse | 2007 | World Journal of Gastroenterology2007，13，5： | 4 |
| 12 | Synergism of essential oils with lipid based nanocarriers: emerging trends in preservation of grains and related food products显示文摘Grains are one of the major food staples in the world.The cereal grains are easily susceptible to damage by moisture content,flour beetles and food pathogens during storage,harvesting and post harvesting.Food preservative techniques namely drying,freezing,and dehydration,acquire little advantages.However,they cause few undesirable alterations in the organoleptic and nutritional properties of the preserved food items.Therefore,there is a continuous search for new preservation techniques in food industries,to satisfy the customer demands on the addition of natural food preservatives,devoid of pathogenic contaminants and without changes in organoleptic properties.Essential oils(EOs)have been predicted as“natural food additives”in the preservative process.The synergistic potential of EOs with various nanocarriers plays an emerging role in the food industry.Therefore,the present review has focused on the lipid based nanocarriers,and the methods used for the functionalization or encapsulation of EOs and applications in the preservation of food items such as cooked rice,rice flour,grains,sliced breads have also been discussed.The present review ascertains the antimicrobial significance of active EOs loaded lipid nanocarriers in the form of nano emulsions,solid lipid nanoparticles and liposomes for preserving grains and flours. | Satyavani Kaliamurthi Gurudeeban Selvaraj Lifen Hou Zhao Li Yongkai Wei Keren Gu Dongqing Wei | 2019 | Grain & Oil Science and Technology2019，2，1： | 4 |
| 13 | Impact of gene mutation in the development of Parkinson’s disease显示文摘Parkinson’s disease(PD)is the second most common age related neurodegenerative disorder worldwide and presents as a progressive movement disorder.Globally seven million to 10 million people have Parkinson’s disease.Parkinsonism is typically sporadic in nature.Loss of dopaminergic neurons from substantia nigra pars compacta(SNpc)and the neuronal intracellular Lewy body inclusions are the major cause of PD.Gene mutation and protein aggregation play a pivotal role in the degeneration of dopamine neurons.But the actual cause of dopamine degeneration remains unknown.However,several rare familial forms of PD are associated with genetic loci,and the recognition of causal mutations has provided insight into the disease process.Yet,the molecular pathways and gene transformation that trigger neuronal susceptibility are inadequately comprehended.The discovery of a mutation in new genes has provided a basis for much of the ongoing molecular work in the PD field and testing of targeted therapeutics.Single gene mutation in a dominantly or recessively inherited gene results a great impact in the development of Parkinson’s disease.In this review,we summarize the molecular genetics of PD. | Suganya Selvaraj Shanmughavel Piramanayagam | 2019 | Genes & Diseases2019，6，2： | 3 |
| 14 | Larvicidal activity of green synthesized silver nanoparticles using bark aqueous extract of Ficus racemosa against Culex quinquefasciatus and Culex gelidus显示文摘Objective:To investigate the larvicidal activity of synthesized silver nanoparticles(Ag NPs) utilizing aqueous bark extract of Ficus racemosa(F.racemosa) was tested against fourth instar larvae of filariasis vector,Culex quinquefasciatus(Cx.quinquefasciatus) and japanese encephalitis vectors,Culex gelidus(Cx.gelidus).Methods:The synthesized Ag NPs was characterized by UV-vis spectrum,X-ray diffraction(XRD),Scanning electron microscopy(SEM) and Fourier transform infrared(FTIR).The larvicidal activities were assessed for 24 h against the larvae of Cx.quinquefasciatus and Cx.gelidus with varying concentrations of aqueous bark extract off.racemosa and synthesized Ag NPs.LC50 and r2 values were calculated.Results:The maximum efficacy was observed in crude aqueous extract of F.racemosa against the larvae of Cx.quinquefasciatus and Cx.gelidus(LC50=67.72 and 63.70 mg/L;r2=0.995 and 0.985) and the synthesized Ag NPs(LC50=12.00 and 11.21 mg/L;r2=0.997 and 0.990).respectively.Synthesized Ag NPs showed the XRD peaks at 2θvalues of 27.61,29.60,35.48,43.48 and 79.68 were identified as (210),(121),(220),(200) and(311) reflections,respectively.The FTIR spectra of Ag NPs exhibited prominent peaks at 3 425,2 878,1 627 and 1 382 in the region 500-3 000 cm-1.The peaks correspond to the presence of a stretching vibration of(NH) C=O group.SEM analysis showed shape in cylindrical,uniform and rod with the average size of 250.60 nm.Conclusions:The biosynthesis of silver nanoparticles using bark aqueous extract of F.racemosa and its larvicidal activity against the larvae of disease spreading vectors.The maximum larvicidal efficacy was observed in the synthesized Ag NPs. | Kanayairam Velayutham Abdul Abdul Rahuman Govindasamy Rajakumar Selvaraj Mohana Roopan Gandhi Elango Chinnaperumal Kamaraj Sampath Marimuthu Thirunavukkarasu Santhoshkumar Moorthy Iyappan Chinnadurai Siva | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，2： | 2 |
| 15 | Mosquitocidal properties of Solanum trilobatum L.(Solanaceae) leaf extracts against,three important human vector mosquitoes(Diptera:Culicidae)显示文摘Objective:To determine the larvicidal and pupicidal activites of Solanum trilobatum(S. trilobatum) leaf extracts against Aedes aegypti(Ae.aegypti),Culex quinquefasciatus(Cx. quinquefasciatus) and Anopheles stephensi(An.stephensi).Methods:The larvicidal and pupucidal was determined at five different concentrations of 50,100,150,200 and 250 ppm.Percentage of larval mortality was assessed after 48 h.Results:Methanol extracts of S.trilobatum was found to be more susceptible against the larvae of Ae.aegypti.Cx.quinquefasciatus and An.stephensi at 250 ppm with a LC_(50) value of 125.43,127.77 and 116.64 ppm respectively.Leaf methanol extracts of S.trilobatum also exhibited pupicidal and adult emergence properties.Conclusions:These results suggested that the leaf extracts of S.Irilobalum showed potential to be used as an ideal ecofriendly approach for the control of the Ae.Aegypti,Cx.quinquefasciatus and An.stephensi. | Selvaraj Premalatha Kuppusamy Elumalai Alagarmalai Jeyasankar | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，11： | 2 |
| 16 | DNA Barcode ITS Effectively Distinguishes the Medicinal Plant Boerhavia diffusa from Its Adulterants显示文摘Boerhavia diffusa (B. diffusa), also known as Punarnava, is an indigenous plant in India and an important component in traditional Indian medicine. The accurate identification and collection of this medicinal herb is vital to enhance the drug's efficacy and biosafety. In this study, a DNA barcoding technique has been applied to identify and distinguish B. diffusa from its closely-related species. The phylogenetic analysis was carried out for the four species of Boerhavia using barcode candidates including nuclear ribosomal DNA regions ITS, ITS1, ITS2 and the chloroplast plastid gene psbA-trnH. Sequence alignment revealed 26% polymorphic sites in ITS, 30% in ITS1, 16% in ITS2 and 6% in psbA-trnH, respectively. Additionally, a phylogenetic tree was constructed for 15 species using ITS sequences which clearly distinguished B. diffusa from the other species. The ITS1 demonstrates a higher transition/transversion ratio, percentage of variation and pairwise distance which differentiate B. diffusa from other species of Boerhavia. Our study revealed that ITS and ITS1 could be used as potential candidate regions for identifying B. diffusa and for authenticating its herbal products. | Dhivya Selvaraj Dhivya Shanmughanandhan Rajeev Kumar Sarma Jijo C. Joseph Ramachandran V. Srinivasan Sathishkumar Ramalingam | 2012 | Genomics, Proteomics & Bioinformatics2012，10，6： | 2 |
| 17 | Carbon Geochemistry of Gas Hydrate-associated Sediments in the Southwestern Taiwan Basin显示文摘Marine gas hydrates, one of the largest methane reservoirs on Earth, may greatly affect the deep sea sedimentary environment and biogeochemistry; however, the carbon geochemistry in gas hydrate-bearing sediments is poorly understood. In this study, we investigated the carbon variables in sediment core 973-3 from the southwestern Taiwan Basin in the South China Sea to understand the effect of environmental factors and archaeal communities on carbon geochemistry. The carbon profiles suggest the methanogenesis with the incerase of dissolved inorganic carbon(DIC) and high total organic carbon(TOC)(mean = 0.46%) originated from terrigenous organic matter(mean δ^(13)C_(TOC) value of-23.6‰) driven by the abundant methanogen ‘Methanosaeta and Methanomicrobiales'. The active anaerobic oxidation of methane is characterized by the increase of DIC and inorganic carbon(IC), and the depleted δ^(13)C_(IC), coupled with the increase of TOC and the decrease of δ^(13)C_(TOC) values owing to the methanotroph ‘Methanosarcinales/ANME' in 430–840 cm. Environmental factors and archaeal communities in core 973-3 are significantly correlated to carbon variables owing to methane production and oxidation. Our results indicate that the carbon geochemical characteristics are obviously responding to the formation and decomposition of gas hydrates. Furthermore, pH, Eh and grain size, and Methanosaeta greatly affect the carbon geochemistry in gas hydrate-associated sediments. | LEI Huaiyan YANG Yufeng Selvaraj KANDASAMY SHI Chunxiao | 2018 | Acta Geologica Sinica(English Edition)2018，92，1： | 2 |
| 18 | Evolving role of magnetic resonance techniques in primary sclerosing cholangitis显示文摘Development of non-invasive methods to risk-stratify patients and predict clinical endpoints have been identified as one of the key research priorities in primary sclerosing cholangitis(PSC). In addition to serum and histological biomarkers, there has been much recent interest in developing imaging biomarkers that can predict disease course and clinical outcomes in PSC.Magnetic resonance imaging/magnetic resonance cholangiopancreatography(MRI/MRCP) continue to play a central role in the diagnosis and follow-up of PSC patients. Magnetic resonance(MR) techniques have undergone significant advancement over the last three decades both in MR data acquisition and interpretation. The progression from a qualitative to quantitative approach in MR acquisition techniques and data interpretation, offers the opportunity for the development of objective and reproducible imaging biomarkers that can potentially be incorporated as an additional endpoint in clinical trials. This review article will discuss how the role of MR techniques have evolved over the last three decades from emerging as an alternative diagnostic tool to endoscopic retrograde cholangiopancreatography, to being instrumental in the ongoing search for imaging biomarker of disease stage, progression and prognosis in PSC. | Emmanuel A Selvaraj Emma L Culver Helen Bungay Adam Bailey Roger W Chapman Michael Pavlides | 2019 | World Journal of Gastroenterology2019，25，6： | 2 |
| 19 | Studies on the Functional Properties of Protein Concentrate of Kappaphycus alvarezii (Doty) Doty – An Edible Seaweed显示文摘 | K. Suresh Kumar K. Ganesan Kandasamy Selvaraj P.V. Subba Rao | 2013 | Food Chemistry2013，，： | 2 |
| 20 | 限制铬鞣过程中的用水量显示文摘工业生产如铬鞣常常需要耗费大量的水,导致全球需求的宝贵资源枯竭。而在胶原基质中铬的水解、扩散、分布和固定,水是必须的。虽然可以通过使用绿色溶剂如生物乙醇使铬鞣所需水量达到最小来获得比较绿色和可持续的解决方案,但这一问题已争议了数年。本研究通过冻干技术显示,对于铬鞣使胶原基质内部含水量最低55%~65%是必须的。通过光学和电子显微镜分析结合x一射线能谱分析证实,随着冷冻时间的延长,皮基质内含水量从65%降低到15%,铬在革中的含量与分布呈线性降低。 | Silambarasan Selvaraj Aravindhan Rathinam Raghava Rao Jonnalagadda 石永固 | 2015 | 西部皮革2015，0，16： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员