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| 1 | Ameliorative effects of bombesin and neurotensin on trinitrobenzene sulphonic acid-induced colitis,oxidative damage and apoptosis in rats显示文摘AIM:To investigate the effects of bombesin (BBS) and neurotensin (NTS) on apoptosis and colitis in an ulcerative colitis model. METHODS:In this study, a total of 50 rats were divided equally into 5 groups. In the control group, no colitis induction or drug administration was performed. Colitis was induced in all other groups. Following the induction of colitis, BBS, NTS or both were applied to three groups of rats. The remaining group (colitis group) received no treatment. On the 11th d after induction of colitis and drug treatment, blood samples were collected for TNF-α and IL-6 level studies. Malondialdehyde (MDA), carbonyl, myeloperoxidase (MPO) and caspase-3 activities, as well as histopathological findings, evaluated in colonic tissues. RESULTS:According to the macroscopic and microscopic findings, the study groups treated with BBS, NTS and BBS + NTS showed significantly lower damage and inflammation compared with the colitis group (macroscopic score, 2.1 ± 0.87, 3.7 ± 0.94 and 2.1 ± 0.87 vs 7.3 ± 0.94;microscopic score, 2.0 ± 0.66, 3.3 ± 0.82 and 1.8 ± 0.63 vs 5.2 ± 0.78, P < 0.01). TNF-α and IL-6 levels were increased significantly in all groups compared with the control group. These increases were significantly smaller in the BBS, NTS and BBS + NTS groups compared with the colitis group (TNF-α levels, 169.69 ± 53.56, 245.86 ± 64.85 and 175.54 ± 42.19 vs 556.44 ± 49.82;IL-6 levels, 443.30 ± 53.99, 612.80 ± 70.39 and 396.80 ± 78.43 vs 1505.90 ± 222.23, P < 0.05). The colonic MPO and MDA levels were significantly lower in control, BBS, NTS and BBS + NTS groups than in the colitis group (MPO levels, 24.36 ± 8.10, 40.51 ± 8.67 and 25.83 ± 6.43 vs 161.47 ± 38.24;MDA levels, 4.70 ± 1.41, 6.55 ± 1.12 and 4.51 ± 0.54 vs 15.60 ± 1.88, P < 0.05). Carbonyl content and caspase-3 levels were higher in the colitis and NTS groups than in control, BBS and BBS + NTS groups (carbonyl levels, 553.99 ± 59.58 and 336.26 ± 35.72 vs 209.76 ± 30.92, 219.76 ± 25.77 and 220.34 ± 36.95;caspase-3 levels, 451.70 ± 68.27 and 216.20 ± 28.17 vs 28.60 ± 6.46, 170.50 ± 32.37 and 166.50 ± 30.95, P < 0.05). CONCLUSION:The results of this study suggest BBS and NTS, through their anti-inflammatory actions, support the maintenance of colonic integrity and merit consideration as potential agents for ameliorating colonic inflammation. | Alper Akcan Sebahattin Muhtaroglu Hulya Akgun Hizir Akyildiz Can Kucuk Erdogan Sozuer Alper Yurci Namik Yilmaz | 2008 | World Journal of Gastroenterology2008，14，8： | 14 |
| 2 | Hepatocellular carcinoma review:Current treatment,and evidence-based medicine显示文摘We read with great interest the recent article entitled'Hepatocellular carcinoma review:Current treatment,and evidence-based medicine'by Raza et al,published in World Journal of Gastroenterology.Authors evaluated treatments for early and advanced stage hepatocellular carcinoma based on an extensive review of the relevant literature.They reported that radiofrequency ablation is the most effective local ablative therapy.They concluded that RF ablation is equivalent to surgical resection in well selected patients with early stage hepatocellular carcinoma.In addition,we want to mention microwave ablation besides RF ablation. | Bulent Karaman Bilal Battal Sebahattin Sari Samet Verim | 2014 | World Journal of Gastroenterology2014，20，47： | 9 |
| 3 | Seroprevalence and genotyping of hepatitis B,hepatitis C and HIV among healthy population and Turkish soldiers in Northern Cyprus显示文摘AIM: To compare the prevalence of hepatitis viral markers among soldiers from Turkey, blood donors from Northern Cyprus, and soldiers from Northern Cyprus. METHODS: Hepatitis B surface antigen (HBsAg), anti- HCV and anti-human immunodeficiency virus (HIV) seroprevalence, HBV DNA, HCV RNA and HCV genotyping among soldiers from Turkey (groupⅠ), civil blood donors from Northern Cyprus (group Ⅱ), and soldier candidates from Northern Cyprus (group Ⅲ) were studied and compared to one another. In total, 17 545 cases (13 546 males and 3999 females with a mean age of 34.5 ± 10.3 year, groupⅠ= 11 234, group Ⅱ = 5057, and group Ⅲ = 1254) were included into the study. RESULTS: Among all cases, HBsAg positivity rates were 2.46%, anti-HCV was 0.46% and anti-HIV was 0.00%. HBV DNA was 2.25%, HCV RNA was 0.33% in all groups. HBsAg positivity rates were 2.16% in groupⅠ, 3.00% in group Ⅱ and 2.71% in group Ⅲ. There was a significant difference between groupⅠand group Ⅱ (χ2 = 6.11, P = 0.047 < 0.05). Anti-HCV positivity rates were 0.45% in groupⅠ, 0.45% in group Ⅱ, and 0.56% in group Ⅲ. Genotypes of HCV were 1b and 1a in groupⅠ, 1b, 1a and 2 in group Ⅱ, and 1b, 1a in group Ⅲ. HBsAg carrier rates were 2.20% in females and 2.53% in males. Anti- HCV prevalence was 0.38% in females and 0.48% in males. HBsAg positivity rates were 2.53% in individuals younger than 50, and 1.47% in older than 50. There was a significant difference between the two groups (χ2 =23.48, P = 0.001). CONCLUSION: Prevalences of HBsAg, HCV and HIV infections in Northern Cyprus population are similar to those of Turkey. | Mustafa Altindis Sebahattin Yilmaz Tansel Dikengil Hamit Acemoglu Salih Hosoglu | 2006 | World Journal of Gastroenterology2006，12，42： | 4 |
| 4 | Blockchain technology in the future of business cyber security and accounting显示文摘This study looks into the current,and potential uses of Blockchain technology in business,specifically in Accounting and in cybersecurity.We relate Blockchain uses to current concerns within cybersecurity and accounting.We review the literature that includes topics such as Big Data in Accounting,blockchain’s use in financial security and cybersecurity,and its use in financial accounting though the use of ledger technology and also as a system of tracking financial misconduct.We also review the Department of Homeland Security plan for cybersecurity over the next few years to understand what the US Government plans because of the importance of cybersecurity development.We show that Blockchain impacts auditing in different ways that will change the profession drastically.We also find that blockchain should be effectively implemented into different aspects of cybersecurity,and accounting,such as Auditing and general accounting procedures. | Sebahattin Demirkan Irem Demirkan Andrew McKee | 2020 | Journal of Management Analytics2020，7，2： | 3 |
| 5 | Production and characterization of ZnO nanoparticles and porous particles by ultrasonic spray pyrolysis using a zinc nitrate precursor显示文摘ZnO nanoparticles and porous particles were produced by an ultrasonic spray pyrolysis method using a zinc nitrate precursor at various temperatures under air atmosphere. The effects of reaction temperature on the size and morphology of ZnO particles were investi-gated. The samples were characterized by energy dispersive spectroscopy, X-ray diffraction, transmission electron microscopy, and scanning electron microscopy. ZnO particles were obtained in a hexagonal crystal structure and the crystallite shapes changed from spherical to hex-agonal by elevating the reaction temperature. The crystallite size grew by increasing the temperature, in spite of reducing the residence time in the heated zone. ZnO nanoparticles were obtained at the lowest reaction temperature and ZnO porous particles, formed by aggregation of ZnO nanoparticles due to effective sintering, were prepared at higher temperatures. The results showed that the properties of ZnO particles can be controlled by changing the reaction temperature in the ultrasonic spray pyrolysis method. | Burak Ebin Elif Arτg Burak zkal Sebahattin Gürmen | 2012 | International Journal of Minerals,Metallurgy and Materials2012，19，7： | 2 |
| 6 | Behcet's syndrome显示文摘 | Sebahattin Y Hasan Y | 2008 | Best Pracrce & Research Clinical Rheumatology2008，22，5： | 1 |
| 7 | The behavior of organic components in copper recovery from electroless plating bath effluents using 3D electrode systems显示文摘 | G?khan Orhan Sebahattin Gürmen Servet Timur | 2004 | Journal of Hazardous Materials2004，，3： | 1 |
| 8 | Acidic Leaching of Scheelite Concentrate and Production of Hetero-poly-tung- state Salt显示文摘 | Sebahattin G Servet T Cuneyt A | 1999 | Hydrometallurgy1999，51，2： | 1 |
| 9 | Synthesis of nanosized spherical cobalt powder by ultrasonic spray pyrolysis显示文摘 | Sebahattin Gurmen Srec ko Stopic Bernd Friedrich | 2006 | Materials Research Bulletin2006，41，： | 1 |
| 10 | Development of innovation strategies for sports education 显示文摘 | SEBAHATTIN D HASAN S MURAT T | 2012 | Social Behav Sci2012，，46： | 1 |
| 11 | The Shortened Cochlea : its Classification and Histopathologic Features显示文摘 | Yiqing Z Patricia AS Sebahattin C | 2002 | Int J Pediatr Otorhi2002，63，1： | 1 |
| 12 | Synthesis of nanosized spherical cobalt powder by ultrasonic spray pyrolysis 显示文摘 | GuRMEN Sebahattin STOPIC Srecko FRIEDRICH Bemd | 2006 | Materials Research Bulletin2006，41，： | 1 |
| 13 | Influence of Ulva meal on growth,feed utilization and body composition of juvenile Nile tilapia(Orechromis niloticuss)at two levels of dietary lipid显示文摘 | Sebahattin E Murat S Betul G | 2009 | Aquaculture International2009，17，： | 1 |
| 14 | Peliosis hepatis: One pathology, a thousand faces, and a clinical and radiological diagnostic challenge显示文摘 | Bilal Battal Veysel Akgun Sebahattin Sari | 2014 | Journal of Digestive Diseases2014，，5： | 1 |
| 15 | Influence of Ulva meal on growth,feed utilization and body composition of juvenile Nile tilapia (Orechromis niloticuss) at two levels of dietary lipid显示文摘 | Sebahattin E Murat S Betul G | 2009 | Aquaculture International2009，17，： | 1 |
| 16 | Financial status, corpo- rate governance qualityand the likelihood of managers u- sing discretionary accruals 显示文摘 | Sebahattin Demirkan Harlan Platt | 2010 | Accounting Research Jour- nal2010，2，22： | 1 |
| 17 | Nonalcoholic fatty liver disease is an independent risk factor for atherosclerosis in young adult men显示文摘 | Kadir Ozturk Ahmet Uygun Ahmet Kerem Guler Hakan Demirci Cafer Ozdemir Mehmet Cakir Yusuf Serdar Sakin Turker Turker Sebahattin Sari Seref Demirbas Y?ld?r?m Karsl?o?lu Mutlu Saglam | 2015 | Atherosclerosis2015，，： | 1 |
| 18 | Clinical features of Beh?et’s disease in children: An international collaborative study of 86 cases显示文摘 | Isabelle Koné-Paut Sebahattin Yurdakul Sultan A. Bahabri Nahid Shafae Seza Ozen Huri ?zdogan Jean Louis Bernard | 1998 | The Journal of Pediatrics1998，，4： | 1 |
| 19 | Susceptibility-Weighted Imaging in the Diagnosis of Isolated Cortical Vein Thrombosis显示文摘 | Battal Bilal Sari Sebahattin Hamcan Salih Akgun Veysel | 2014 | 2014 (1-2)2014，，1： | 1 |
| 20 | Clinical features of behcet'disease in children: A international collaborative study of 86 cases 显示文摘 | Labelle KP Sebahattin Y Sultan A | 1998 | J Pediatr1998，132，： | 1 |
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