|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Demographics, societal aging, and meat consumption in China显示文摘Drawn on the data collected by surveying 1 340 urban households from six cities in China, this paper estimates the impacts of demographic structure and population aging on household meat consumption, by jointly considering meat consumed at home and away from home. Based on the trajectories of population, a simple simulation on meat demand trend in China is conducted subsequently. The results suggest: 1) Meat consumed away from home averagely accounts for near 30% of household total meat consumption in terms of quantity, so that its omission likely leads to a significant underestimate of total meat consumption and misunderstanding the driving forces; 2) population aging significantly and negatively affects per capita meat consumption, suggesting that the expected meat demand in China without considering population aging will be overestimated. The findings from this study have important implications for better understanding the relative issues on China's meat consumption under the situation of population aging. | MIN Shi BAI Jun-fei James Seale Jr. Thomas Wahl | 2015 | Journal of Integrative Agriculture2015，14，6： | 11 |
| 2 | 非洲裔美国人体力活动与高血压发生的相关性显示文摘非洲裔美国人在美国各种族(民族)中高血压患病率(男性为40.8%,女性为41.5%)最高。有证据表明,与美国其他种族(民族)相比,非洲裔美国人高血压与因心肌梗死、脑卒中和终末期肾脏疾病引起的过早功能丧失和死亡呈不成比例地升高相关。需要确定控制非洲裔美国人危险因素的措施,以减轻其发生高血压的风险。在许多其他人群中已证实,体力活动对预防高血压有保护作用。因此,高血压指南推荐采用体力活动作为预防性生活行为方式。 | Diaz KM Booth JN 3rd Seals SR Abdalla M Dubbert PM Sims M Ladapo JA Redmond N Muntner P Shimbo D | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 3 | Bemisia tabaci Phylogenetic Groups in India and the Relative Transmission Efficacy of Tomato leaf curl Bangalore virus by an Indigenous and an Exotic Population显示文摘Bemisia tabaci adults from various host-plant species were collected from 31 regions across India.266 B.tabaci samples were first screened by RAPD-PCR to examine molecular variability and to select individuals with different fingerprints.Host-plant and region of collection were then used to select 25 individuals for PCR amplification and sequencing of their partial mitochondrial cytochrome oxidase subunit one(mtCOI)genes.Pairwise comparisons with mtCOI consensus sequences showed that the majority of these samples had <3.5% sequence divergence from groups currently termed Asia I,Asia II-5,Asia II-7,and Asia II-8.The biotype-B B.tabaci from India clustered into the Middle East-Asia Minor 1 group.A new group of B.tabaci from Coimbatore,collected from pumpkin,was related most closely to the Asia I group(6.2% sequence divergence from the consensus Asia I sequence).To increase our understanding of the epidemiology of tomato leaf curl disease(ToLCD)and the key B.tabaci genetic groups involved in virus spread,the indigenous Asia I and the exotic biotype-B population from South India were used to carry out transmission experiments using Tomato leaf curl Bangalore virus(ToLCBV).The acquisition access periods(AAP),inoculation access periods(IAP),latent periods(LP),and ToLCBV transmission efficiencies of the two populations were compared and the biotype-B had the more efficient transmission characteristics.These results are discussed in relation to recent changes in the epidemiology of tomato leaf curl disease in South India. | R V Chowda-Reddy M Kirankumar Susan E Seal V Muniyappa Girish B Valand M R Govindappa John Colvin | 2012 | Journal of Integrative Agriculture2012，11，2： | 8 |
| 4 | 医务人员呼吸道感染影响因素的巢式病例对照研究显示文摘目的探索医务人员在院内感染呼吸道传染病的影响因素,针对性的提出院感防范重点及感染控制改进建议。方法本研究采用巢式病例对照研究的方法。选取北京市东城区和西城区的9家二级以上医院,将符合条件的医务人员作为一个队列,对其医疗行为进行为期一个月的观察。依据咽拭子病原学检测结粜削定研究对象的呼吸道感染状况,并将他们分为病例组和对照组。通过问卷调查了解并比较肼组人员在职、眦暴露与防护行为等方面的差异。数据分析应用STATA11.0软件完成,危险因素的分析采用非条件Logistic回归。结果共有481名医务人员完成本次研究,随访率为100%。在481名研究对象中有40例经实验室确诊为呼吸道感染,纳入病例组,其他441人纳入对照组。单因素分析显示,医院级别、工作科室、高危操作、接触病人后洗手等四个因素可能与医务人员发生呼吸道感染相关。多因素非条件logistic回归分析发现,共有2个因素进入回归方程,其中从事高危操作(OR=2.42,95%CI1.06~5.50)为发生呼吸道感染的危险因素,接触病人后洗手(OR=0.41,95%CI0.19—0.89)为保护性因素。结论为防止医务人员在院内感染呼吸道传染病,针对其危险因素所采取的干预措施亟待开展。 | 张奕 Chandini Raina MacIntyre 杨鹏 Holly Seale 王小莉 刘文婷 Simon Cauchemez Neil Ferguson 王全意 | 2011 | 国际病毒学杂志2011，18，5： | 4 |
| 5 | Next Generation Transcriptome Sequencing and Quantitative Real-Time PCR Technologies for Characterisation of the Bemisia tabaci Asia 1 mtCOI Phylogenetic Clade显示文摘A programme of functional genomics research is underway at the University of Greenwich,UK,to develop and apply genomics technologies to characterise an economically-important but under-researched Bemisia tabaci(Hemiptera:Aleyrodidae),the Asia 1 mtCOI phylogenetic group.A comparison of this putative species from India with other important B.tabaci populations and insect species may provide targets for the development of more effective whitefly control strategies.As a first step,next-generation sequencing(NGS)has been used to survey the transcriptome of adult female whitefly,with high quality RNA preparations being used to generate cDNA libraries for NGS using the Roche 454 Titanium DNA sequencing platform.Contig assemblies constructed from the resultant sequences(301 094 reads)using the software program CLC Genomics Workbench generated 3 821 core contigs.Comparison of a selection of these contigs with related sequences from other B.tabaci genetic groups has revealed good alignment for some genes(e.g.,HSP90)but misassemblies in other datasets(e.g.,the vitellogenin gene family),highlighting the need for manual curation as well as collaborative international efforts to obtain accurate assemblies from the existing next generation sequence datasets.Nevertheless,data emerging from the NGS has facilitated the development of accurate and reliable methods for analysing gene expression based on quantitative real-time RT-PCR,illustrating the power of this approach to enable rapid expression analyses in an organism for which a complete genome sequence is currently lacking. | Susan Seal Mitulkumar V Patel Carl Collins John Colvin David Bailey | 2012 | Journal of Integrative Agriculture2012，11，2： | 2 |
| 6 | FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation显示文摘Tyrosine kinase inhibitors(TKIs)targeting FLT3 have shown activity but when used alone have achieved limited success in clinical trials,suggesting the need for combination with other drugs.We investigated the combination of FLT3 TKIs(Gilteritinib or Sorafenib),with Venetodax,a BCL-2 selective inhibitor(BCL-2i),on FLT3/ITD leukemia cells.The combination of a FLT3 TKI and a BCL-2i synergistically reduced cell proliferation and enhanced apoptosis/cell death in FLT3/ITD cell lines and primary AML samples.Venetoclax also re-sensitized FLT3 TKI-resistant cells to Gilteritinib or Sorafenib treatment,mediated through MAPK pathway inhibition.Gilteritinib treatment alone dissociated BIM from MCL-1 but increased the binding of BIM to BCL-2.Venetoclax treatment enhanced the binding of BIM to MCL-1 but dissociated BIM from BCL-2.Treatment with the drugs together resulted in dissociation of BIM from both BCL-2 and MCL-1,with an increased binding of BIM to the cell death mediator BAX,leading to increased apoptosis.These findings suggest that Venetoclax mitigates the unintended pro-survival effects of FLT3 TKI mainly through the dissociation of BIM and BCL-2 and also decreased BIM expression.This study provides evidence that the addition of BCL-2i enhances the effect of FLT3 TKI therapy in FLT3/ITD AML treatment. | Ruiqi Zhu Li Li Bao Nguyen Jaesung Seo Min Wu Tessa Seale Mark Levis Amy Duffield Yu Hu Donald Small | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 7 | Temperature-insensitive microwave absorption of TiB2-Al_(2)O_(3)/MgAl_(2)O_(4) ceramics based on controllable electrical conductivity显示文摘The design of the high-temperature microwave absorbing materials (MAMs) with temperature-insensitive and considerable microwave absorption (MA) capacity is a tremendous challenge.Ti B2-Al_(2)O_(3)/Mg Al_(2)O_(4) MAMs are prepared by the spark plasma sintering (SPS).Further,the influences of the Al_(2)O_(3) content on the flexural strength,thermal stability,high-temperature electrical conductivity,dielectric and MA properties are discussed.The results show that the Al_(2)O_(3) content is associated with flexural strength,high-temperature thermal stability,electrical conductivity,dielectric and MA properties.Meanwhile,the temperatureinsensitive and considerable MA properties with the minimum reflection loss (RLmin) ranging from -19.4 to -14.3 dB and the effective absorption bandwidth (EAB,RL<-5 dB) of 3.19–3.55 GHz are attained at 25°C–700°C in 8.2–12.4 GHz as the Al_(2)O_(3) content increases from 70.6 wt%to 80.6 wt%.This is ascribed to the compensating effect of the positive and negative temperature coefficient materials on the high-temperature electrical conductivity as well as the co-play of the dipolar and interfacial polarization at elevated temperatures.Consequently,Ti B2-Al_(2)O_(3)/Mg Al_(2)O_(4) ceramics exhibit the ideal prospect as the high-temperature MAMs. | LIU XiongZhang ZHANG Sealing LUO Hui CHEN Fu LI DongMeng WANG Xian GONG RongZhou | 2021 | Science China(Technological Sciences)2021，64，6： | 2 |
| 8 | Transcriptional Control of Brown Fat Development显示文摘 | Shingo Kajimura Patrick Seale Bruce M. Spiegelman | 2010 | Cell Metabolism2010，，4： | 2 |
| 9 | Using on-site liver 3-D reconstruction and volumetric calculations in split liver transplantation显示文摘BACKGROUND: Split liver transplantation increases the number of grafts available for transplantation. Pre-recovery assessment of liver graft volume is essential for selecting suitable recipients. The purpose of this study was to determine the ability and feasibility of constructing a 3-D model to aid in surgical planning and to predict graft weight prior to an in situ division of the donor liver. METHODS: Over 11 months, 3-D volumetric reconstruction of 4 deceased donors was performed using Pathfinder Scout~? liver volumetric software. Demographic, laboratory, operative, perioperative and survival data for these patients along with donor demographic data were collected prospectively and analyzed retrospectively.RESULTS: The average predicted weight of the grafts from the adult donors obtained from an in situ split procedure were 1130 g(930-1458 g) for the extended right lobe donors and 312 g(222-396 g) for left lateral segment grafts. Actual adult graft weight was 92% of the predicted weight for both the extended right grafts and the left lateral segment grafts. The predicted and actual graft weights for the pediatric donors were 176 g and 210 g for the left lateral segment grafts and 308 g and 280 g for the extended right lobe grafts, respectively. All grafts were transplanted except for the right lobe from the pediatric donors due to the small graft weight.CONCLUSIONS: On-site volumetric assessment of donors provides useful information for the planning of an in situ split and for selection of recipients. This information may expand the donor pool to recipients previously felt to be unsuitable due to donor and/or recipient weight. | Trevor W Reichman Brittany Fiorello Ian Carmody Humberto Bohorquez Ari Cohen John Seal David Bruce George E Loss | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，6： | 2 |
| 10 | Graphene based materials: Past, present and future显示文摘 | Virendra Singh Daeha Joung Lei Zhai Soumen Das Saiful I. Khondaker Sudipta Seal | 2011 | Progress in Materials Science2011，，8： | 2 |
| 11 | 成本-效果分析中药物成本测量的良好研究规范:Medicare和Medicaid计划以及其他美国政府支持者角度——ISPOR药物成本工作组报告之四显示文摘目的:公共项目为美国的药物支出提供了大部分的财政支持。截至目前,仍然没有相关指南来估算由美国公共项目资助的药物的成本。本研究的目的是为估算由美国公共项目支持的药物的成本提供标准,以便将其用于药物经济学评价。方法:本报告由国际药物经济学与结果研究协会(ISPOR)的专项计划——成本-效果分析中药物成本测量的良好研究规范工作组中的美国政府角度即美国医疗保险计划(Medicare)和医疗补助计划(Medicaid)以及其他美国政府支付者角度的专门小组撰写。该小组的任务是对研究者在估算由美国公共项目资助药物的成本时所遇到的方法学及实际问题进行评价,以便提出适用于更透明、更准确和更具一致性的成本计算的标准。结果:该小组提出了以下建议:(1)研究者必须考虑会对由公共项目所支付的药物成本产生影响的管理要求;(2)药物成本必须反映真实的购置成本,包括所有的回扣和折扣;(3)必须确保成本投入的相关透明度;(4)推荐包括公共项目的视角;(5)需要特别关注高成本药物,尤其当某一特殊疾病所用药物占卫生保健支出很大比例时;(6)由于公共项目之间的差异,必须对实际购置成本、实际依从性以及仿制药的可获得性进行敏感性分析。此外还对Medicare和Medicaid提出了特别建议。结论:随着对美国公共项目覆盖政策而进行的药物经济学评价越来越多,必须保证药物成本估算的准确性和一致性。以上建议的执行将允许研究者在药物经济学评价当中使用准确、无偏倚的成本估算。 | C Daniel Mullins Brian Seal Enrique Seoane-Vazquez 郑亚明 宗欣 吴晶 | 2011 | 中国药物经济学2011，，5： | 2 |
| 12 | Changing structure of China's meat imports显示文摘This paper discusses the determinants of meat imports of China. Results indicate that import demand is mostly determined by import price and real GDP. Imported price has a negative effect and real GDP has a positive influence on import quantity. Tariff does not have a significant effect. As GDP and consumption capacity increases, China has a large potential demand for meat imports. Some countries may gain if China's economy continues expanding, while others, like the United States, are the most sensitive to the trade policy of China. | CHENG Ya-hao Zhifeng Gao James Seale Jr. | 2015 | Journal of Integrative Agriculture2015，14，6： | 2 |
| 13 | All-weather model for sky luminance distribution-preliminary configuration and validation 显示文摘 | Perez R Seals R Michalsky J | 1993 | Solar Energy1993，50，3： | 1 |
| 14 | Numerical Calculation of the Probability of Ruin in the Poisson /Exponential Case显示文摘 | | 1972 | Mitteilangen der Vereinigung Schmeicerscher Versicherungs Mathem Atiker1972，，2： | 1 |
| 15 | Open-hole completion system enables multi-stage fracturing and stimulation along horizontal wellbores显示文摘 | SEALE ROCKY PACKERSPLUS | 2007 | Drilling Contractor2007，，8： | 1 |
| 16 | Gender accommodation in online cancer support groups显示文摘 | Seale C | 2006 | Health2006，10，3： | 1 |
| 17 | PRDM16 controls a brown fat/skeletal muscle switch显示文摘 | SEALE P BJORK B YANG W L | 2008 | Nature2008，454，7207： | 1 |
| 18 | Evaluation of Newcastle disease virus chimeras expressing the Hemagglutinin-Neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone显示文摘 | Estevez C King D Seal B Yu Q | 2007 | Virus Res2007，129，2： | 1 |
| 19 | Winter fasting and refeeding effects on urine characteristics in white-tailed deer显示文摘 | DelGiudice G D Mech L D Seal U S Kams P D | 1987 | J Wildl Manage1987，51，： | 1 |
| 20 | Surface Chemical Reactivity in Selected Zero-Valent Iiron Samples Used in Groundwater Remediation显示文摘 | Ruiz N Seal S Reinhart D | 2000 | Journal of Hazardous Materials2000，80，13： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员