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| 1 | 医务人员呼吸道感染影响因素的巢式病例对照研究显示文摘目的探索医务人员在院内感染呼吸道传染病的影响因素,针对性的提出院感防范重点及感染控制改进建议。方法本研究采用巢式病例对照研究的方法。选取北京市东城区和西城区的9家二级以上医院,将符合条件的医务人员作为一个队列,对其医疗行为进行为期一个月的观察。依据咽拭子病原学检测结粜削定研究对象的呼吸道感染状况,并将他们分为病例组和对照组。通过问卷调查了解并比较肼组人员在职、眦暴露与防护行为等方面的差异。数据分析应用STATA11.0软件完成,危险因素的分析采用非条件Logistic回归。结果共有481名医务人员完成本次研究,随访率为100%。在481名研究对象中有40例经实验室确诊为呼吸道感染,纳入病例组,其他441人纳入对照组。单因素分析显示,医院级别、工作科室、高危操作、接触病人后洗手等四个因素可能与医务人员发生呼吸道感染相关。多因素非条件logistic回归分析发现,共有2个因素进入回归方程,其中从事高危操作(OR=2.42,95%CI1.06~5.50)为发生呼吸道感染的危险因素,接触病人后洗手(OR=0.41,95%CI0.19—0.89)为保护性因素。结论为防止医务人员在院内感染呼吸道传染病,针对其危险因素所采取的干预措施亟待开展。 | 张奕 Chandini Raina MacIntyre 杨鹏 Holly Seale 王小莉 刘文婷 Simon Cauchemez Neil Ferguson 王全意 | 2011 | 国际病毒学杂志2011,18,5: | 4 |
| 2 | Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes显示文摘AIM To establish the impact of portal hypertension(PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease(PCLD) listed for liver transplantation. METHODS A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters:(1) presence of radiological or endoscopic documented varices from our own centre or the referral centre;(2) splenomegaly(> 11 cm) on radiology inabsence of splenic cysts accounting for increased imaging size;(3) thrombocytopenia(platelets < 150 × 109/L); or(4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst. RESULTS Forty-seven PCLD patients(F: M = 42: 5) were listed for liver transplantation(LT)(single organ, n = 35; combined liver-kidney transplantation, n = 12) with 19 patients(40.4%) having PH. When comparing the PH group with non-PH group, the mean listing age(PH group, 50.6(6.4); non-PH group, 47.1(7.4) years; P = 0.101), median listing MELD(PH group, 12; non-PH group, 11; P = 0.422) median listing UKELD score(PH group, 48; non-PH group, 46; P = 0.344) and need for renal replacement therapy(P = 0.317) were similar. In the patients who underwent LT alone, there was no difference in the duration of ICU stay(PH, 3 d; non-PH, 2 d; P = 0.188), hospital stay length(PH, 9 d; non-PH, 10 d; P = 0.973), or frequency of renal replacement therapy(PH, 2/8; non-PH, 1/14; P = 0.121) in the immediate post-transplantation period. CONCLUSION Clinically apparent portal hypertension in patients with PCLD listed for liver transplantation does not appear to have a major impact on wait-list or peri-transplant morbidity. | Neil Rajoriya Dhiraj Tripathi Joanna A Leithead Bridget K Gunson Sophie Lord James W Ferguson Gideon M Hirschfield | 2016 | World Journal of Gastroenterology2016,22,45: | 2 |
| 3 | Issues in end-of-life product recovery and reverse logistics 显示文摘 | Neil Ferguson Browne | 2001 | Production Planning and Control2001,12,5: | 1 |
| 4 | Issues in end- of-life product recovery and reverse logistics 显示文摘 | Neil Ferguson Jim Browne | 2001 | Production Planning & Control2001,12,5: | 1 |
| 5 | Epidemic and intervention modelling - a scientific rationale for policy decisions? Lessons from the 2009 influenza pandemic显示文摘 | Kerkhove Maria D Van Ferguson Neil M | 2012 | EN2012,,4: | 1 |
| 6 | 南非Hluhluwe-Umfolozi公园植被对非洲狮群大小的影响(英文)显示文摘非洲狮(Pantheraleo)群处于不断的分裂-聚合过程,其亚群大小与原狮群大小以及诸如狮群捕食成功度、协作幼仔保护及狮群领域防卫等社会性因素有关。我们分析了南非一个保护区(Hluhluwe-Umfolozi公园)15年间的狮群大小,其成年雌狮和成年雄狮群的大小在保护区内呈显著性变化。在开放生境中雌狮结大群,而茂密植被生境中则结小群。雄狮群大小与植被类型无关,但在大的雌狮群分布区域发现大雄狮群。令人惊奇的是,作为幼狮成活率指标的幼狮群大小和雌狮平均幼仔数在保护区内没有显著性差异。我们认为,雌狮群大小的不同是对植被结构的适应,即在开放生境中大群有利于协作狩猎、育幼、共同保护幼仔、应对高强度群间领域防卫竞争。相反,茂密植被中,群间竞争很低,高密度植被覆盖有利于狩猎成功及补偿小狮群对幼仔保护的不足。雌狮平均幼仔数在整个保护区内没有变化。 | Martina TRINKEL Ryan William VAN NIEKERK Paul Herbert FLEISCHMANN Neil FERGUSON Rob SLOTOW | 2007 | 动物学报2007,53,1: | 0 |
| 7 | 传染病流行的数学预测显示文摘传染病流行是疾病在人群中传播的连锁反应。由于疾病在人群中流行的过程相对简单,所以有时可以用数学模型来描述甚至预测。所谓“简单”是指感染和疾病进展以个体从一种状态转变成另一种状态为特征。例如,从未感染或易感状态转变为感染状态,或从接触感染者转变为感染状态,或因感染恢复并且获得免疫力由感染期转入恢复期。因此,模型的建立将包括个体感染状态的分类以及导致感染状态相互转变的过程。建立预测模型的目的旨在预测随着时间的推移,不同人群所占比例的变化以及疾病相关事件的发生率。本文着重讨论了疾病流行的数学模型,但类似的方法也可用于对感染者病毒或细菌感染发病机制的研究。 | Neil M Ferguson 朱卫国(译) 盛瑞媛(校) | 2006 | 国际内科双语杂志(中英文)2006,6,3: | 0 |