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| 1 | Adhesive small bowel obstruction after appendectomy in children: comparison between the laparoscopic and open approach显示文摘 | Kuo Jen Tsao Shawn D. St Peter Patricia A. Valusek Scott J. Keckler Susan Sharp George W. Holcomb Charles L. Snyder Daniel J. Ostlie | 2007 | Journal of Pediatric Surgery2007，，6： | 2 |
| 2 | Safety,immunogenicity,and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates显示文摘Although antivirals are important tools to control severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,effective vaccines are essential to control the current coronavirus disease 2019(COVID-19)pandemic.Plant-derived virus-like particle(VLP)vaccine candidates have previously demonstrated immunogenicity and efficacy against influenza.Here,we report the immunogenicity and protection induced in rhesus macaques by intramuscular injections of a VLP bearing a SARS-CoV-2 spike protein(CoVLP)vaccine candidate formulated with or without Adjuvant System 03(AS03)or cytidine-phospho-guanosine(CpG)1018.Although a single dose of the unadjuvanted CoVLP vaccine candidate stimulated humoral and cell-mediated immune responses,booster immunization(at 28 days after priming)and adjuvant administration significantly improved both responses,with higher immunogenicity and protection provided by the AS03-adjuvanted CoVLP.Fifteen micrograms of CoVLP adjuvanted with AS03 induced a polyfunctional interleukin-2(IL-2)-driven response and IL-4 expression in CD4 T cells.Animals were challenged by multiple routes(i.e.,intratracheal,intranasal,and ocular)with a total viral dose of 106 plaque-forming units of SARS-CoV-2.Lower viral replication in nasal swabs and bronchoalveolar lavage fluid(BALF)as well as fewer SARS-CoV-2-infected cells and immune cell infiltrates in the lungs concomitant with reduced levels of proinflammatory cytokines and chemotactic factors in the BALF were observed in animals immunized with the CoVLP adjuvanted with AS03.No clinical,pathologic,or virologic evidence of vaccineassociated enhanced disease was observed in vaccinated animals.The CoVLP adjuvanted with AS03 was therefore selected for vaccine development and clinical trials. | Stéphane Pillet Prabhu SArunachalam Guadalupe Andreani Nadia Golden Jane Fontenot Pyone Pyone Aye Katharina Röltgen Gabrielle Lehmicke Philipe Gobeil Charlotte Dubé Sonia Trépanier Nathalie Charland Marc-AndréD’Aoust Kasi Russell-Lodrigue Christopher Monjure Robert V.Blair Scott D.Boyd Rudolf P.Bohm Jay Rappaport François Villinger Nathalie Landry Bali Pulendran Brian J.Ward | 2022 | Cellular & Molecular Immunology2022，19，2： | 2 |
| 3 | Intravenous vernakalant:a review of its use in the management of recent-onset atrial fibrillation显示文摘 | DUGGAN ST SCOTT LJ | 2011 | Drugs2011，71，2： | 1 |
| 4 | 显示文摘 | Cox ST Marsh SG Scott I | 1999 | Tissue Antigens1999，53，1： | 1 |
| 5 | Clair,Enhancement of dimensional stability in soluble fluorinated polyimides via the in situ formation of lanthanum(Ⅲ)-oxo-polyimide nanocomposites显示文摘 | Robin E Southward D Scott Thompson David W Thompson Anne K St | 1998 | Chem Mater1998，10，： | 1 |
| 6 | Spotlight on intravenous vernakalant in recent- onset atrial fibrillation 显示文摘 | Duggan ST Scott LJ | 2011 | Drugs Aging2011，25，6： | 1 |
| 7 | Pretreatment of wood and cellulose for production of sugars by fast pyrolysis显示文摘 | JAN piskorz DESMOND St A G Radlein DONALD S Scott | 1989 | J Anal Appl Pyrolysis1989，16，： | 1 |
| 8 | Current role of PET, CT, Mr for invasive bladder cancer显示文摘 | Lawrentschuk N Lee ST Scott AM | 2013 | Curr Urol Rep2013，14，2： | 1 |
| 9 | Intravenous paracetamol显示文摘 | Duggan ST Scott LJ | 2009 | Drugs2009，69，1： | 1 |
| 10 | Morphine/naltrexone显示文摘 | Duggan ST Scott LJ | 2010 | CNS Drugs2010，24，6： | 1 |
| 11 | Depressive symptoms predict smoking status among pregnant women显示文摘 | Linares Scott TJ Heil SH Higgins ST | 2009 | Addict Behav2009，34，8： | 1 |
| 12 | 5-Fluorouracilacil toxici ty on small intestinal mucosa but not white blood cells is decreased by glutami ne显示文摘 | O'Dwyer ST Scott T Smith RJ | 1987 | Clin Res1987，35，： | 1 |
| 13 | Morphine/nahrexone显示文摘 | Duggan ST Scott LJ | 2010 | CNS Drugs2010，24，6： | 1 |
| 14 | Shock metamorphism of ordinary chondrites显示文摘 | St?ffler D Keil K Scott Edward R D | | 0，，12： | 1 |
| 15 | Laparoscopic marsupialization andhemisplenectomy for splenic cysts 显示文摘 | Smith ST Scott DJ Burdick JS | 2001 | J Laparoendosc Adv Surg Tech2001，11，： | 1 |
| 16 | Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson’s disease: a dose escalation, open-label, phase 1/2 trial显示文摘 | Stéphane Palfi Jean Marc Gurruchaga G Scott Ralph Helene Lepetit Sonia Lavisse Philip C Buttery Colin Watts James Miskin Michelle Kelleher Sarah Deeley Hirokazu Iwamuro Jean Pascal Lefaucheur Claire Thiriez Gilles Fenelon Cherry Lucas Pierre Brugières Ina | 2014 | The Lancet2014，，： | 1 |
| 17 | Active avoidance conditioning in zebrafish (Danio rerio)显示文摘 | Xu X Scott ST Kempker L Simons K | | 0，，01： | 1 |
| 18 | Current role of PET, CT, Mr for invasive bladder Cancer显示文摘 | Lawrentschuk N Lee ST Scott AM | 2013 | Curr Urol Rep2013，14，2： | 1 |
| 19 | Academic achievement among first semester undergraduate psychology students: the role of course experience, effort, motives and learning strategies显示文摘 | ?ge Diseth St?le Pallesen Geir Scott Brunborg Svein Larsen | 2010 | Higher Education2010，，3： | 1 |
| 20 | 显示文摘 | Piskorz J St A G Radlien D Scott D S | 1989 | Journal of Analytical and Applied Pyrolysis1989，16，2： | 1 |
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