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| 1 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014，20，46： | 21 |
| 2 | 腹腔镜外科学基础认证项目简介及其对中国外科医师的意义显示文摘腹腔镜外科学基础(FLS)项目是普通外科中第1个经过验证的操作和认知考核项目.FLS由美国胃肠内镜外科医师协会(SAGES)开发并得到美国外科医学委员会(ABS)的支持.ABS要求所有拟参加普通外科医师执业资格考试前必须通过FLS考试.在美国,普通外科医师执业资格考试是取得执业资格的第一步.本文回顾了FLS项目在美国取得的成功经验,并就该项目在中国推广标准化腹腔镜外科技术中的应用和获益进行了介绍. | Linda P Zhang Samuel R G Finlayson Allan Okrainec Steven D Schwaitzberg | 2014 | 中华消化外科杂志2014，13，9： | 5 |
| 3 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘 | Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet | 2009 | Lancet Oncology2009，，5： | 4 |
| 4 | Corrosion rate determination of rare-earth Mg alloys in a Na_(2)SO_(4)solution by electrochemical measurements and inductive coupled plasma-optical emission spectroscopy显示文摘The corrosion resistance of three Mg alloys containing rare-earth elements(WE43,EV31 and ZE41)was studied and compared to that of two Mg-Al alloys(AZ31 and AZ91)and of pure Mg(99.95 wt.%).Current-voltage curves and electrochemical impedance measurements were performed with rotating disk electrodes in an aerated 0.1 M Na_(2)SO_(4)solution.For all the alloys,it was confirmed that the intermetallic particles acted as local cathodes and that more protective films were formed on the alloys surface by comparison with the pure Mg.Corrosion rates were determined from inductive coupled plasma-optical emission spectroscopy measurements and from the electrochemical measurements.Higher corrosion rates were observed for the rare-earth Mg alloys compared to the AZ series alloys.These data allowed the corrosion mechanisms to be discussed. | Samuel Leleu Bertrand Rives Nicolas Causse Nadine Pébère | 2019 | Journal of Magnesium and Alloys2019，7，1： | 3 |
| 5 | Evaluating land surface moisture conditions from the remotely sensed temperature/vegetation index measurements显示文摘 | Samuel N Goward Yongkang Xue Kevin P Czajkowski | 2001 | Remote Sensing of Environment2001，，2： | 2 |
| 6 | Pullout performance of inclined helical screw anchors in sand 显示文摘 | Ashraf M Ghaly Samuel P Clemence | 1998 | Journal of Geotechnical and Geo-environmental Engineering1998，124，7： | 2 |
| 7 | 肥胖Zucker大鼠肾脏血管紧张素Ⅱ2型受体及Mas受体共定位,且功能相互依赖显示文摘血管紧张素Ⅱ2型受体(angiotensinⅡtype 2receptor,AT_2R)与Mas受体(the receptor Mas,MasR)作用复杂,但均具有相似的前利钠作用,尤其是在肥胖/糖尿病大鼠肾脏中AT_2R表达及利钠作用增强。根据一些报道提示的这些受体之间的潜在正相互作用,研究者在肥胖大鼠中验证肾脏AT_2R及MasR生理上相互作用、相互依赖地刺激细胞信号转导及促进利钠作用的假设。 | Patel SN Ali Q Samuel P Steckelings UM Hussain T 赵狄 练桂丽 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 8 | Inhibition of Mast Cell Leukotriene Release by Thiourea Derivatives显示文摘 | Venkatachalam T K Qazi S Samuel P | 2003 | Bioorg Med Chem Lett2003，13，： | 1 |
| 9 | Cloning and sequencing of a Shiga - like toxin type II variant from Esche- richia coli strain responsible for edema disease of swine 显示文摘 | WEINSTEIN D L JACKSON M P SAMUEL J E | 1988 | Bacteri- ol1988，170，9： | 1 |
| 10 | Pregnancy-associated thrombocytopenia: pathogenesis and management 显示文摘 | McCrae K R Samuels P Schreiber A D | 1992 | Blood1992，80，： | 1 |
| 11 | Cloning and sequencing of a Shiga-like toxin type Ⅱ variant from Escherichia coli strain responsible for edema disease of swine显示文摘 | WEINSTEIN D L JACKSON M P SAMUEL J E | 1988 | J Bacteriol1988，170，9： | 1 |
| 12 | Design, analysis and hover performance of a rotary wing micro air vehicle显示文摘 | BOHORQUEZ F SAMUEL P SIROHI J | 2003 | Journal of the American Helicopter Society2003，48，2： | 1 |
| 13 | After twenty years : the future of thethird wave显示文摘 | Samuel Huntington P | 1997 | Journal of Democracy1997，8，4： | 1 |
| 14 | The PIK3CA gene is mutated with high frequency in human breast cancers显示文摘 | Bachman KE Argani P Samuels Y | | 0，，08： | 1 |
| 15 | Biosynthesis of O-antigens:genes and pathways involved in nucleotide sugar precursor synthesis and O-antigen assembly显示文摘 | Samuel G Reeves P | 2003 | Carbohyd Res2003，33，： | 1 |
| 16 | The G_2/M regulator 14-3-3 sigma prevents apoptosis through sequestration of Bax显示文摘 | Samuel T Weber HO Ranch P | 2001 | J Biol Chem2001，276，45： | 1 |
| 17 | Orientation of silk Ⅲat the air-water interface显示文摘 | Regina V Samuel P Wayne M | 1999 | International Journal of Biological Macromolecules1999，24，2： | 1 |
| 18 | Observation of a non-constant mean curvature interface in an ABC tribloek copolymer显示文摘 | Samuel P Gido Dwight W Schwark Edwin L Thomas | 1993 | Macromolecules1993，26，： | 1 |
| 19 | A review of vibration-based tech- niques for helicopter transmission diagnostics显示文摘 | Samuel P D Pines D J | 2005 | Journal of Sound and Vibration2005，282，12： | 1 |
| 20 | Aberrant lymphoid antigen expression of CD7,CD56,CD79a antigens in acute my- eloid leukemia 显示文摘 | JULUIS MC ROBERT EL SAMUEL P | 2005 | Exp Mol Pathol2005，79，1： | 1 |
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