|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis显示文摘AIM: To study the safety of epidural anesthesia(EA),its effect on pancreatic perfusion and the outcome of patients with acute pancreatitis(AP).METHODS: From 2005 to August 2010,patients with predicted severe AP [Ranson score ≥ 2,C-reactive protein > 100 or necrosis on computed tomography(CT)] were prospectively randomized to either a group receiving EA or a control group treated by patientcontrolled intravenous analgesia. Pain management was evaluated in the two groups every eight hours using the visual analog pain scale(VAS). Parameters for clinical severity such as length of hospital stay,use of antibiotics,admission to the intensive care unit,radiological/clinical complications and the need for surgical necrosectomy including biochemical data were recorded. A CT scan using a perfusion protocol was performed on admission and at 72 h to evaluate pancreatic blood flow. A significant variation in blood flow was defined as a 20% difference in pancreatic perfusion between admission and 72 h and was measured in the head,body and tail of the pancreas.RESULTS: We enrolled 35 patients. Thirteen were randomized to the EA group and 22 to the control group. There were no differences in demographic characteristics between the two groups. The Balthazar radiological severity score on admission was higher in the EA group than in the control group(mean score 4.15 ± 2.54 vs 3.38 ± 1.75,respectively,P = 0.347) and the median Ranson scores were 3.4 and 2.7 respectively(P = NS). The median duration of EA was 5.7 d,and no complications of the epidural procedure were reported. An improvement in perfusion of the pancreas was observed in 13/30(43%) of measurements in the EA group vs 2/27(7%) in the control group(P = 0.0025). Necrosectomy was performed in 1/13 patients in the EA group vs 4/22 patients in the control group(P = 0.63). The VAS improved during the first ten days in the EA group compared to the control group(0.2 vs 2.33,P = 0.034 at 10 d). Length of stay and mortality were not statistically different between the 2 groups(26 d vs 30 d,P = 0.65,and 0% for both respectively).CONCLUSION: Our study demonstrates that EA increases arterial perfusion of the pancreas and improves the clinical outcome of patients with AP. | Samira M Sadowski Axel Andres Philippe Morel Eduardo Schiffer Jean-Louis Frossard Alexandra Platon Pierre-Alexandre Poletti Leo Bühler | 2015 | World Journal of Gastroenterology2015，21，43： | 21 |
| 2 | Hydrotherapy Versus Conventional Land-Based Exercise for the Management of Patients With Osteoarthritis of the Knee: A Randomized Clinical Trial显示文摘 | Silva Luciana E Valim Valeria Pessanha Ana Paula C Oliveira Leda M Myamoto Samira Jones Anamaria Natour Jamil | 2008 | Physical Therapy2008，，1： | 2 |
| 3 | Exosomes for targeted siRNA delivery across biological barriers显示文摘 | Samir EL A Samira L Imre M | 2013 | Adv Drug Deliv Rev2013，65，3： | 1 |
| 4 | Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats显示文摘 | Leda S B Garcia Clariss M Comim Samira S Valvassori | | 0，，03： | 1 |
| 5 | Recovery of rat submandibular salivary gland function following removal of obstruction: a sialometrical and sialochemical study 显示文摘 | Samira M Osailan Gordon B Proctor Guy H Carpenter | 2007 | International Journal of Experimental Pathology2007，87，6： | 1 |
| 6 | Fabrication of electrochemical theophylline sensor based on manganese oxide nanoparticles/ionic liquid/chitosan nanocomposite modified glassy carbon electrode显示文摘 | SAMIRA M HAZHIR T ABDOLLAH S | 2014 | Electrochim Acta2014，108，1： | 1 |
| 7 | Mast cell activation by mycobacterium tuberculosis: mediator release and role of CD48显示文摘 | Samira M Rogelio HP Soman NA | 2003 | J Immunol2003，170，11： | 1 |
| 8 | Conditioning DRASTIC model to simulate nilrate pollution case study: Hamadan - Bahar Plain 显示文摘 | Samira A Sayed F M Jahangir A K | 2011 | Environment Earth Science2011，63，6： | 1 |
| 9 | The Use of Soya Bean,Sunflower and Lupin Seeds in the Preparation of Pro- tein Bases for Nutritious Beverages显示文摘 | Fakhriya S T Samira S M Ahmed S E | 1986 | Journal of the Science of Food and Agriculture1986，37，12： | 1 |
| 10 | Studies on the morphology and histology of the ovary of red palm weevil female irradiated with gamma rays 显示文摘 | Samira E M Hussein F Eman A | 2010 | Joumal of Asia-Pacific Entomology2010，13，： | 1 |
| 11 | Long-Term Shedding of Infectious Epstein-Barr Virus after Infectious Mononucleosis显示文摘 | Samira F K Patrice M Jean-Paul B | 2006 | Journal of Infectious Diseases2006，191，6： | 1 |
| 12 | Meat ageing: reconsideration of the current concept显示文摘 | CARLOS H M SAMIRA B ABDELGHANI B | 2006 | Trends in Food Science & Technology2006，17，8： | 1 |
| 13 | Diffusion of I ,2-dime- thoxyethane and I, 2-dimethoxypropane through phosphatidy- choline bilayers: a molecular dynamics study显示文摘 | Susruta S Samira H Giuseppe M | 2012 | The Journal of Chemical Physics B2012，116，： | 1 |
| 14 | Farfield radia- ted from a vertical magnetic dipole in the sea with a rough upper surface显示文摘 | OSAMA M ABO SEIDA SAMIRA TADROS BISHAY KHALED MOHAMED EL MORABIE | 2006 | IEEE Transactions on Geoscience and Remote Sesing2006，44，8： | 1 |
| 15 | Purification, molecular cloning, and cell specific gene expression of the alkaloid-accu mulation associated protein CrPS in Catharanthus roseus 显示文摘 | Diane L Lazhar O Samira M | 2005 | Journal Experimental Botany2005，56，414： | 1 |
| 16 | Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature显示文摘 | Anice CL Samira M John S | 2007 | Plo S Pathogens2007，3，10： | 1 |
| 17 | Overexpression of adiponectin targeted to adipose tissue in transgenic mice : impaired adipocyte differentiation显示文摘 | Isabelle B B Samira A E Anne M P | 2007 | Endocrinology2007，148，4： | 1 |
| 18 | Apparent Diffusion Coefficient: a quantitative parameter for in vivo tumor characterization显示文摘 | Andreas M Herneth Samira Guccione Mark Bednarski | 2002 | European Journal of Radiology2002，，3： | 1 |
| 19 | Expression and purification of recombinant ROP1 of Toxoplasma gondii in bacteria显示文摘 | Reyhaneh M Jalal B Samira A | 2013 | Avicenna Journal of Medical Biotechnology2013，5，4： | 1 |
| 20 | Constructing BiVO4/Graphene/TiO2 nanocomposite photoanode for photoelec- trochemical conversion applications 显示文摘 | Samira Y Monireh F Alireza Z M | 2016 | J Electroanal Chem2016，763，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员