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| 1 | Vitamin D and autoimmune thyroid diseases显示文摘The role of vitamin D as an immune modulator has been emphasized in recent years,and low levels of the hormone were observed in several autoimmune diseases including multiple sclerosis and systemic lupus erythematosus.Vitamin D mediates its effect though binding to vitamin D receptor(VDR),and activation of VDR-responsive genes.While VDR gene polymorphism was found to associate with autoimmune thyroid diseases(AITDs),few studies examined levels of vitamin D in these patients and those that did yielded conflicting results.We therefore undertook to evaluate the levels of vitamin D in patients with AITDs compared to patients with non-AITDs and healthy controls.Serum vitamin D(25-OH)levels were measured in 50 patients with AITDs,42 patients with non-AITDs and 98 healthy subjects,utilizing the LIAISON chemiluminescence immunoassay(DiaSorin,Saluggia,Italy).VitaminD deficiency was designated at levels lower than 10 ng/ml.Antithyroid antibodies,thyroid functions and demographic parameters were evaluated in all patients.The prevalence of vitamin D deficiency was significantly higher in patients with AITDs compared with healthy individuals(72% versus 30.6%;P<0.001),as well as in patients with Hashimoto’s thyroiditis compared to patients with non-AITDs(79% versus 52%;P<0.05).Vitamin D deficiency also correlated to the presence of antithyroid antibodies(P=0.01)and abnormal thyroid function tests(P=0.059).Significantly low levels of vitamin D were documented in patients with AITDs that were related to the presence of anti thyroid antibodies and abnormal thyroid function tests,suggesting the involvement of vitamin D in the pathogenesis of AITDs and the advisability of supplementation. | Shaye Kivity Nancy Agmon-Levin Michael Zisappl Yinon Shapira Endre V Nagy Katalin Danko Zoltan Szekanecz Pnina Langevitz Yehuda Shoenfeld | 2011 | Cellular & Molecular Immunology2011，8，3： | 47 |
| 2 | Nonlinear optical holograms for spatial and spectral shaping of light waves显示文摘Shaping either the spatial or the spectral output of a nonlinear interaction is accomplished by introducing basic concepts of computer-generated holography into the nonlinear optics regime. The possibilities of arbitrarily spatially shaping the result of a nonlinear interaction are presented for different phase-matching schemes allowing for both one- and two-dimensional shaping. Shaping the spectrum of a beam in nonlinear interaction is also possible by utilizing similar holographic techniques. The novel and complete control of the output of a nonlinear interaction opens exciting options in the fields of particle manipulation, optical communications, spectroscopy and quantum information. | Asia Shapira Liran Naor Ady Arie | 2015 | Science Bulletin2015，60，16： | 6 |
| 3 | 中国科研成果的引用增长是否存在“俱乐部效应”?显示文摘越来越多的实证数据显示,中国科研发表的被引频次正在迅速上升。不同的解释相继提出。本研究探讨了另一种可能性——中国研究的被引频次激增是否存在'俱乐部效应',(2)即高影响力的中国科研论文会有更高的内部援引率。以纳米技术这一交叉新兴领域作为研究素材,我们发现中国高被引论文在个体、科研机构以及国家三个层次上较大比例的引用来源于内部网络。描述性和统计检验表明,与美国同类论文相比,中国高被引论文的内部引用更为显著。文末就该'俱乐部现象'进行了诠释并提出相关政策建议。 | 唐莉 Philip Shapira Jan Youtie | 2016 | 财经研究2016，42，10： | 4 |
| 4 | Hyperbaric oxygen therapy as a new treatment approach for Alzheimer's disease显示文摘Hyperbaric oxygen therapy as a new treatment approach for Alzheimer’s disease(AD):Alongside the increase in life expectancy,the prevalence of age-related disorders,such as neurodegenerative diseases,is on the rise.For example,AD,the most common form of dementia in the elderly,accounts for 60–80%of all dementia cases. | Ronit Shapira Shai Efrati Uri Ashery | 2018 | Neural Regeneration Research2018，13，5： | 3 |
| 5 | 基于科学计量的中国人工智能区域知识创新生态系统研究显示文摘本文在提出新兴技术知识创新生态系统研究方法的基础上,选择中国人工智能产业作为案例,以期为中国人工智能区域发展提供政策建议。本文首先建立一个分析框架,以研究新兴技术知识创新生态系统,并使用科学计量学研究方法和社会网络分析方法来研究中国人工智能知识创新生态系统。本文主要分析中国人工智能创新过程中的主要参与者,人工智能知识创新的区域分布,核心区域创新集群以及其形成的过程;并从社会网络角度分析参与者在集群形成过程中扮演的角色和他们之间的关系。结果表明,中国人工智能知识创新集群已经广泛出现,受科技资源分布影响明显,地理邻近性仅在同一行政区范围内明显,区域协同发展战略和地方政府的创新发展政策有助于帮助区域打破行政界限,实现人工智能领域的区域协同创新。 | 岳晓旭 苏竣 Philip Shapira 谢其军 | 2021 | 中国科技论坛2021，，8： | 3 |
| 6 | 唐山与通海两大地震的强余震的差别及其原因探讨显示文摘1970年通海地震序列与1976年唐山地震序列的对比表明,两次地震的余震衰减,余震强度和频度,余震分布区的形状等有区别。对此提出了一种解释:若余震分布区域的长轴长度a与短轴长度b之比a/b越大,则震源体越接近于一个面,在一个面上进行的调整过程应当比较简单,余震的衰减比较快,强余震比较少而小;反之则震源体越表现出一个体的形态,在一个体内进行的调整过程应当比较复杂,余震衰减比较慢,强余震比较多而大。对于那些在主震后能够很快进行定位并勾画出余震区域轮廓的情况,可以尝试利用a/b快速判断后面强余震的多少以及余震衰减的快慢。 | 李保昆 刁桂苓 Avi Shapira 冯向东 | 2009 | 西北地震学报2009，31，2： | 2 |
| 7 | Helicobacter pylori serology in autoimmune diseases – fact or fiction?显示文摘 | Maya Ram Ori Barzilai Yinon Shapira Juan-Manuel Anaya Angela Tincani Ljudmila Stojanovich Stefano Bombardieri Nicola Bizzaro Shaye Kivity Nancy Agmon Levin Yehuda Shoenfeld | 2013 | Clinical Chemistry and Laboratory Medicine2013，，5： | 2 |
| 8 | The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study显示文摘 | Donald S Silverberg Dov Wexler David Sheps Miriam Blum Gad Keren Ron Baruch Doron Schwartz Tatyana Yachnin Shoshana Steinbruch Itzhak Shapira Shlomo Laniado Adrian Iaina | 2001 | Journal of the American College of Cardiology2001，，7： | 2 |
| 9 | Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells显示文摘 | Piyush B. Gupta Christine M. Fillmore Guozhi Jiang Sagi D. Shapira Kai Tao Charlotte Kuperwasser Eric S. Lander | 2011 | Cell2011，，4： | 2 |
| 10 | Control of root-knot nematodes in organic farming systems by organic amendments and soil solarization显示文摘 | Oka Y Shapira N Fine P | 2007 | Crop Protection2007，26，： | 1 |
| 11 | Evaluation of openlabel topiramate for scar therapy显示文摘 | Shapira NA Lessig M Murphy TK | 2003 | Dermatol Online J2003，9，5： | 1 |
| 12 | The trimodal death distribution of trauma victims : Militaryexperience from the lebanon war显示文摘 | Gofrit ON Leihovici D Shapira SC | 1997 | Mil Med1997，162，1： | 1 |
| 13 | Mastoidectomy reconstruction of the posterior wall and obliteration(MAPRO):preliminary results显示文摘 | Kronenberg J Shapira Y Migirov L | | 0，，04： | 1 |
| 14 | Adoptive cell therapy with autologous tumor-infiltratinglymphocytes and high-dose interleukin- 2 for metastatic melanoma:The surgeon~ perspective 显示文摘 | Zippel DB Besser M Shapira R | 2012 | Exp T- her Med2012，3，5： | 1 |
| 15 | The effect of stress on the inflammatory response to Porphyromonas gingivalis in a mouse subcutaneouschambermodel显示文摘 | Shapira L Houri-Haddad Y Frolov I | 1999 | JPeriodontol1999，70，3： | 1 |
| 16 | Polysaccharideoligoamine based conjugates for gene delivery 显示文摘 | TONY AZZAM HAGIT ELIYAHU LIBI SHAPIRA | 2002 | J Med Chem2002，45，9： | 1 |
| 17 | Managerial perspectives on risk and risk taking显示文摘 | March J G Shapira Z | 1987 | Management Science1987，33，： | 1 |
| 18 | 5-HT-1A receptor-mediated effects of antidepressants 显示文摘 | Newman ME Lerer B Shapira B | 1993 | Prog Neuropsychopharmaeol Biol Psychiatry1993，17，1： | 1 |
| 19 | On the nature of burnout-insomnia relationships:A prospretive study of employed adults显示文摘 | Armon G Shirom A Shapira I | 2008 | J Psychosom Res2008，65，1： | 1 |
| 20 | Functional -1 Binding to Liposomes in the Absence of a Protein Receptor and Its Relationship to a Predicted Tertiary Structure 显示文摘 | Chen Y H Shapira R Characterization of Pediocin PA Eisenstein M | 1997 | Applied and Environmental Microbiology1997，63，2： | 1 |
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