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| 1 | Vitamin D and autoimmune thyroid diseases显示文摘The role of vitamin D as an immune modulator has been emphasized in recent years,and low levels of the hormone were observed in several autoimmune diseases including multiple sclerosis and systemic lupus erythematosus.Vitamin D mediates its effect though binding to vitamin D receptor(VDR),and activation of VDR-responsive genes.While VDR gene polymorphism was found to associate with autoimmune thyroid diseases(AITDs),few studies examined levels of vitamin D in these patients and those that did yielded conflicting results.We therefore undertook to evaluate the levels of vitamin D in patients with AITDs compared to patients with non-AITDs and healthy controls.Serum vitamin D(25-OH)levels were measured in 50 patients with AITDs,42 patients with non-AITDs and 98 healthy subjects,utilizing the LIAISON chemiluminescence immunoassay(DiaSorin,Saluggia,Italy).VitaminD deficiency was designated at levels lower than 10 ng/ml.Antithyroid antibodies,thyroid functions and demographic parameters were evaluated in all patients.The prevalence of vitamin D deficiency was significantly higher in patients with AITDs compared with healthy individuals(72% versus 30.6%;P<0.001),as well as in patients with Hashimoto’s thyroiditis compared to patients with non-AITDs(79% versus 52%;P<0.05).Vitamin D deficiency also correlated to the presence of antithyroid antibodies(P=0.01)and abnormal thyroid function tests(P=0.059).Significantly low levels of vitamin D were documented in patients with AITDs that were related to the presence of anti thyroid antibodies and abnormal thyroid function tests,suggesting the involvement of vitamin D in the pathogenesis of AITDs and the advisability of supplementation. | Shaye Kivity Nancy Agmon-Levin Michael Zisappl Yinon Shapira Endre V Nagy Katalin Danko Zoltan Szekanecz Pnina Langevitz Yehuda Shoenfeld | 2011 | Cellular & Molecular Immunology2011，8，3： | 47 |
| 2 | Helicobacter pylori serology in autoimmune diseases – fact or fiction?显示文摘 | Maya Ram Ori Barzilai Yinon Shapira Juan-Manuel Anaya Angela Tincani Ljudmila Stojanovich Stefano Bombardieri Nicola Bizzaro Shaye Kivity Nancy Agmon Levin Yehuda Shoenfeld | 2013 | Clinical Chemistry and Laboratory Medicine2013，，5： | 2 |
| 3 | The benign partial nonrolandic epilepsies显示文摘 | Lerman P Kivity S | 1991 | J Clin Neurophysiol1991，8，3： | 1 |
| 4 | Regulatory T ceils : the suppressor ann of the immune system显示文摘 | Langier S Sade K Kivity S | 2010 | Autoimmun Rev2010，10，2： | 1 |
| 5 | Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice显示文摘 | Hochhauser E Kivity S Offen D | 2003 | Am J Physiol Heart Circ Physiol2003，284，6： | 1 |
| 6 | Regulatory T cells: the suppressor arm of the immune system 显示文摘 | Langier S Sade K Kivity S | 2010 | Autoimmun Rev2010，10，2： | 1 |
| 7 | Cognitive function in idiopathic generalized epilepsy of childhood显示文摘 | Henkin Y Sadeh M Kivity S | 2005 | Dev Med Child Neurol2005，47，2： | 1 |
| 8 | Long-term cognitive outcomes of a cohort of children with cryptogenic infantile spasms treated with high-dose adrenocor-ticotropic hormone显示文摘 | KIVITY S LERMAN P ARIEL R | 2004 | Epilepsia2004，45，3： | 1 |
| 9 | Baxablation protects against myocardial ischemia-reperfusion injury in transgenic mice显示文摘 | Hochhauser E Kivity S Offen D Maulik N Otani H Barhum Y | 2003 | Am J Physiol Heart Circ Physiol2003，284，6： | 1 |
| 10 | Bax ablation protects a- gainst myocardial ischemia--reperfusion injury in transgenic mice 显示文摘 | HochhauserE Kivity S Offen D | 2003 | Am J PhysioI Heart Circ Physiol2003，284，6： | 1 |
| 11 | Abnormal olfactory function demonstrated by manganese-enhanced MRI in mice with experimental neuropsychiatric lupus显示文摘 | Kivity S Tsarfaty G Agmon-Levin N | 2010 | Ann NY Acad Sci2010，1193，1： | 1 |
| 12 | Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice显示文摘 | Hochhauser E Kivity S Offen D | 2008 | Am J Physiol Heart Circ Physiol2008，284，6： | 1 |
| 13 | Epidemiology of bronchial asthma and chronic rhinitis in schoolchildren of different ethnic origins from two neighboring towns in Isra- el 显示文摘 | Kivity S Sade K Abu - Arisha F | 2001 | Pediatr Pulmonol2001，32，3： | 1 |
| 14 | Benign occipital epilepsies of childhood : clinical features and genetics 显示文摘 | Taylor I Berkovic SF Kivity S Scheffer IE | 2008 | Brain2008，131，9： | 1 |
| 15 | Regulatory T cells:the suppressor arm of the immune system 显示文摘 | Langier S Sade K Kivity S | 2010 | Autoimmun Rev2010，10，2： | 1 |
| 16 | Bax ablation protects against myocardial ischemia-repeffusion injury in transgenic mice显示文摘 | HOCHHAUSER E KIVITY S OFFEN D | 2003 | Am J Physiol Heart Circ Physiol2003，284，6： | 1 |
| 17 | Regulatory T ceils in allergic asthma显示文摘 | Langier S Sade K Kivity S | 2012 | Chest2012，，3： | 1 |
| 18 | PRRT2 muta- tions cause benign familial infantile epilepsy and infantile convulsions with choreoathetosis syndrome 显示文摘 | Heron SE Grinton BE Kivity S | 2012 | Am J Hum Genet2012，90，1： | 1 |
| 19 | Sensitization to Dermatophagoi- des, Blomia tropicalis, and other mites in atopic patients显示文摘 | Sade K Roitman D Kivity S | 2010 | J Asthma2010，47，8： | 1 |
| 20 | Regulatory T cells in allergic asthma显示文摘 | Langier S Sade K Kivity S | 2012 | Isr Med Assoc J2012，14，： | 1 |
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