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42篇 您的检索式:作者名="SCULLIN"
    题名 作者 年代 出处 被引量
1Re-challenge chemotherapy with gemcitabine plus carboplatin in patients with non-small cell lung cancer显示文摘Despite recent improvements to current therapies and the emergence of novel agents to manage advanced non-small cell lung cancer(NSCLC),the patients′overall survival remains poor.Re-challenging with first-line chemotherapy upon relapse is common in the management of small cell lung cancer but is not well reported for advanced NSCLC.NSCLC relapse has been attributed to acquired drug resistance,but the repopulation of sensitive clones may also play a role,in which case re-challenge may be appropriate.Here,we report the results of re-challenge with gemcitabine plus carboplatin in 22 patients from a single institution who had previously received gemcitabine plus platinum in the first-line setting and had either partial response or a progression-free interval of longer than 6 months.In this retrospective study,the charts of patients who underwent second-line chemotherapy for NSCLC in our cancer center between January 2005 and April 2010 were reviewed.All the patients who received a combination of gemcitabine and carboplatin for re-challenge were included in the study.These patients were offered second-line treatment on confirmation of clear radiological disease progression.The overall response rate was 15%and disease control rate was 75%.The median survival time was 10.4 months,with 46%of patients alive at 1 year.These results suggest that re-challenge chemotherapy should be considered in selected patients with radiological partial response or a progression-free survival of longer than 6 months to the initial therapy.Khurum Khan Gerard G Hanna Lynn Campbell Paula Scullin Adnan Hussain Ruth L Eakin Jonathan McAleese 2013Chinese Journal of Cancer2013,32,10:3
2Contributions of SERCA pump and ryanodine-sensitive stores to presynaptic residual Ca2+显示文摘Scullin CS Partridge LD 2010Cell Calcium2010,47,4:1
3Sleep, cognition, and normal aging:integrating a half century of multidisciplinary research 显示文摘Scullin MK Bliwise DL 2015PerspectPsychol Sci2015,10,1:1
4查看详情显示文摘Yu C Scullin M L Huijben M 0,,19:1
5A HRG-based costing model for estimating pharmacy costs associated with surgical procedures显示文摘Scullin C Scott MG Gribbin M 2004J Clin Pharm Ther2004,29,:1
6Phase Ⅱ study of gemcitabin and cisplatin in locally advanced/metastatic oesophageal cancer显示文摘Millar J Scullin P Morrison A 2005Br J Cancer2005,93,10:1
7Phase II study of gemcitabine and cisplatin in locally advanced/metastatic oesophageal cancer 显示文摘Millar J Scullin P Morrison A 2005Br J Cancer2005,93,10:1
8New advances in the second- line treatment of small cell lung cancer 显示文摘Hurwitz JL McCoy F Scullin P 2009Oncologist2009,14,10:1
9Focal/nonfocal cue effects in prospective memory: Monitoring difficulty or different re- trieval processes显示文摘SCULLIN M K MCDANIEL M A SHELTON J T 2010Journal of Experimental Psychology : Learning Memory and Cognition2010,36,3:1
10Inter- leukin-8 signaling promotes androgen-independent prolif- eration of prostate cancer cells via induction of androgen receptor expression and activation 显示文摘SEATON A SCULLIN P MAXWELL P J 2008Carcinogenesis2008,29,6:1
11Surfactant-assisted synthesis of water-soluble and biocompatible semiconductor quantum dot micelles显示文摘Fan H Y Leve E W Scullin C 2005Nano Lett2005,5,4:1
12Interleukin- 8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation 显示文摘Seaton A Scullin P Maxwell PJ 2008Carcinogenesis2008,29,6:1
13New advances in the second-line treatment of small cell lung cancer显示文摘Hurwitz JL McCoy F Scullin P 0,,:1
14Paclitaxel,carboplatin and topotecan in the treatment of patients with small cell lung cancer:a phase Ⅱtrial of the Minnie Pearl Cancer Research Network显示文摘Hainsworth JD Morrissery LH Scullin DC 2002Cancer2002,94,9:1
15PhaseⅡstudy of gemcitabine and cisplatin in locally advanced/metastatic oesophageal cancer显示文摘Millar J Scullin P Morrison A 2005Br J Cancer2005,93,10:1
16The development of antichotinergies in the management of COPD 显示文摘Scullin JE 2007Int J Chron Obstruct Pulmon Dis2007,2,1:1
17Phase Ⅱ study of gemcitabine and cisplatin in locally advanced/metastatic oesophageal cancer显示文摘Millar J Scullin P Morrison A 2005Br J Cancer2005,93,10:1
18Phase Ⅱ study of gemcitabine and cisplatin in locally advanced/metastatic oesophageal cancer显示文摘Millar J Scullin P Morrison A 2005Br J Cancer2005,93,10:1
19Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression andactivation显示文摘SEATON A SCULLIN P MAXWELL P J 0,,06:1
20Phase lI study of gemcitabine and cisplatin in locally advanced/metastatic oesophageal cancer显示文摘Millar J Scullin P Morrison A 2005Br J Cancer2005,93,10:1
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