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| 1 | Effects of probiotic supplementation on abdominal pain severity in pediatric patients with irritable bowel syndrome:a systematic review and meta-analysis of randomized clinical trials显示文摘Background Probiotic supplementation has been used to alleviate abdominal pain in children and adolescents with irritable bowel syndrome(IBS),but the evidence is not compelling.Thus,a systematic review and meta-analysis of randomized clinical trials(RCTs)were performed to investigate the effects of probiotic supplementation on abdominal pain in pediatric patients with IBS.Methods PubMed/MEDLINE,Web of Science,Scopus,Cochrane Library,and Embase were the available databases searched to find relevant randomized clinical trials up to April 2021.The effect size was expressed as weighted mean differenee(WMD)and 95% confidence interval(CI).Results Seven RCTs with 441 participants were included,from which the meta-analysis demonstrated that probiotic supplementation has a significant effect on reducing abdominal pain in pediatric patients with IBS(WMD=-2.36:95%CI-4.12 to-0.60;P=0.009).Although our study involved children and adolescents(≤18 years),the effects of probiotic supplementation seem to be more potent in patients under 10 years old(WMD=-2.55;95%CI-2.84 to -2.27)compared to patients aged 10-18 years(WMD=-1.70;95%CI-2.18 to -1.22).The length of supplementation longer than four weeks was more effective(WMD=-2.43;95%CI-2.76 to -2.09).Conclusion Probiotic supplementation can reduce abdominal pain in pediatric patients with IBS. | Somayeh Fatahi Amirhossein Hosseini Mohammad Hassan Sohouli Aliakbar Sayyari Katayoun Khatami Zahra Fazeli Farsani Hamzeh Amiri Naghi Dara Ivan G.O.de Souza Heitor O.Santos | 2022 | World Journal of Pediatrics2022，18，5： | 5 |
| 2 | Efficacy and safety of treatment of hepatitis C virus infection in renal transplant recipients显示文摘AIM: To assess the efficacy and safety of combinedpegylated interferon and ribavirin therapy in hepatitis C virus (HCV) infection in renal transplant recipients. METHODS: This is a retrospective chart review of post renal transplant patients who were positive for anti-HCV and HCV-RNA, and who have received treatment with combination of pegylated interferon and ribavirin between October 2003 and December 2008. Only patients with stable graft function and absence of evidence of cirrhosis and who received the therapy for continuous 48 wk were included. Nineteen patients (13 male and 6 female) were identified and included. The patient's complete blood count, liver and kidney prof ile, and cal- culated glomerular f iltration rate (GFR) were monitored every 6-8 wk while on treatment. HCV-RNA was tested at 12 wk for early virological response, at 48 wk for end of treatment response (ETR), and then retested at 24, and 48 wk after completion of therapy for sustained virological response (SVR). Liver biopsies were obtained before treatment from all patients and graft kidney biopsies were performed as required. RESULTS: Of the entire cohort, 9 patients (47.4%) showed an ETR and 8 had SVR (42.1%). Of the 8 patients with abnormal alanine aminotransferase (ALT) levels at baseline, 78.9% had their ALT normalized (including the virological non responders). ALT was normal in all responders at the end of therapy and at 24 wk post therapy (100%). Only one patient (5.3%) developed an increase in creatinine and decline in GFR from baseline towards the end of treatment. This patient's kidney biopsy revealed borderline rejection. There was no impact on response by HCV-genotype, initial HCV RNA load, age or sex of the patient or duration post transplant before commencement of therapy. All patients tolerated treatment in the same way as non-transplant with no unusual or increased occurrence of side effects. CONCLUSION: The combination of pegylated interferon and ribavirin is effective in suppressing HCV-RNA,with a low risk of graft rejection or failure in HCV infected renal transplant recipients. | Abdulrahman A Aljumah Mohamed A Saeed Ahmed I Al Flaiw Ibrahim H Al Traif Abduljaleel M Al Alwan Salem H Al Qurashi Ghormallah A Al Ghamdi Fayez F Al Hejaili Mohammed A Al Balwi Abdulla A Al Sayyari | 2012 | World Journal of Gastroenterology2012，18，1： | 2 |
| 3 | Usefulness of susceptibility weighted imaging for voxel placement in spectroscopy 显示文摘 | Josey L A1 Sayyari A Buchley R | 2009 | AHNR2009，30，： | 1 |
| 4 | Vapour treatments with methyl salicy-late or methyl jasmonate alleviated chilling injury and enhancedantioxidant potential during postharvest storage of pomegranates显示文摘 | SAYYARI M BABALAR M KALANTARI S GUILLEN F SERRANO M VALERO D | 2011 | Food Chemistry2011，124，3： | 1 |
| 5 | Effect of salicylic acid treatment on reducing chilling injury in stored pomegranates 显示文摘 | Sayyari M Babalar M Kalantari S | 2009 | Postharvest Biology and Technology2009，53，3： | 1 |
| 6 | Screening panel-reactive antibody negative,single-antigen positive: a case report显示文摘 | Jawdat D Qurashi SA Sayyari AA | 2014 | Prog Transplant2014，24，4： | 1 |
| 7 | Effect of salicylic acid treatment on reducing chilling injury in stored pomegranates显示文摘 | SAYYARI M BABALAR M KALANTARI S | 2009 | Postharvest Biol Techno2009，53，： | 1 |
| 8 | Effect of salicylic acid treatment on reducing chillinginjury in stored pomegra-nates显示文摘 | SAYYARI M BABALAR M KALANTARI S | 2009 | Postharvest BiologyandTechnology2009，53，3： | 1 |
| 9 | Vapour treatments with methyl salicylate or methyl jasmonate alleviated chilling injury and enhanced antioxidant po- tential during postharvest storage of pomegranates 显示文摘 | Sayyari M Babalar M Kalantari S | 2011 | Food Chemisty2011，124，3： | 1 |
| 10 | Distinguishing recurrent primary brain tumor from radiation injury:a preliminary study using a susceptibility-weighted MR imaging-guided apparent diffusion coefficient analysis strategy显示文摘 | Al Sayyari A Buckley R McHenery C | | 0，，6： | 1 |
| 11 | Prevalence of vitamin D deficiency in Saudi adults显示文摘 | Alsuwadia AO Farag YM Al Sayyari AA | 2013 | Saudi Med J2013，34，8： | 1 |
| 12 | Clinically relevant physical benefits of exercise interventions in breast cancer survivors 显示文摘 | Kirkham AA Bland KA Sayyari S | 2015 | Curt Oncol Rep2015，18，2： | 1 |
| 13 | Usefulness of susceptibilityweighted Imaging for voxel placement in MR spectroscopy 显示文摘 | Josey L Al Sayyari A Buckley R | 2009 | AJNR2009，30，： | 1 |
| 14 | Role of heat treatment, calcium chloride and potassium permanganate on storage life and fruit firmness of Golden Delicious apple (Malus domestica Borkh)显示文摘 | Sayyari M Rahemi M | 2003 | Journal of Science and Technology of Agriculture and Natural Resources2003，6，4： | 1 |
| 15 | Prestorage oxalic acid treatment maintained visual quality, bioactive compounds, and antioxidant potential of pomegranate after long-term storage at 2 ℃ 显示文摘 | Sayyari M Valero D Babalar M | 2010 | Journal of Agricultural and Food Chemistry2010，58，11： | 1 |
| 16 | Acetyl salicylic acid alleviates chilling injury and maintains nutritive and bioactive compounds and antioxidant activity during postharvest storage of pomegranates显示文摘 | Sayyari M Castillo S Valero D | 2011 | Postharvest Biology and Technology2011，60，2： | 1 |
| 17 | Effect of salicylic acid treatment on reducing chilling injury in stored pomegranates显示文摘 | M. Sayyari M. Babalar S. Kalantari M. Serrano D. Valero | 2009 | Postharvest Biology and Technology2009，，3： | 1 |
| 18 | Effect of salicylic acid treatment on reducing chilling injury in stored pomeg-ranates显示文摘 | SAYYARI M BABALAR M KALANTARI S | | 0，，03： | 1 |
| 19 | Effect of salicylic acid treatment on reducing chilling injury in stored pomegranates显示文摘 | SAYYARI M BABALAR M KALANTARI S | | 0，，03： | 1 |
| 20 | Effect of salicylic acid treatment on reducing chilling injury in stored pomegranates显示文摘 | SAYYARI M BABALAR M KALANTARI S | 2009 | Postharvest Biol Technol2009，53，3： | 1 |
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