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| 1 | T-cell ageing in end-stage renal disease patients:Assessment and clinical relevance显示文摘End-stage renal disease(ESRD) patients have a defective T-cell-mediated immune system which is related to excessive premature ageing of the T-cell compartment.This is likely to be caused by the uremia-associated pro-inflammatory milieu,created by loss of renal function.Therefore,ESRD patients are highly susceptible for infections,have an increased risk for virus-associated cancers,respond poorly to vaccination and have an increased risk for atherosclerotic diseases.Three ageing parameters can be used to assess an immunological T-cell age.First,thymic output can be determined by assessing the T-cell receptor excision circlescontent together with CD31 expression within the naive T cells.Second,the telomere length of T cells and third the T-cell differentiation status are also indicators of T-cell ageing.Analyses based on these parameters in ESRD patients revealed that the immunological T-cell age is increased by on average 20 years compared to the chronological age.After kidney transplantation(KTx) the aged T-cell phenotype persists although the pro-inflammatory milieu is diminished.This might be explained by epigenetic modifications at hematopoietic stem cells level.Assessment of an immunological T-cell age could be an important tool to identify KTx recipients who are at risk for allograft rejection or to prevent over-immunosuppression. | Ruud WJ Meijers Michiel GH Betjes Carla C Baan Nicolle HR Litjens | 2014 | World Journal of Nephrology2014，3，4： | 2 |
| 2 | Determination of polar organophosphorus pesticides in vegetables and fruits using liquid chromatography with tandem mass spectrometry: selection of extraction solvent显示文摘 | Mol Hans G J Ruud C J Odile M | 2003 | Journal of Chromatography A2003，1015，： | 1 |
| 3 | A review of selected non-destructive methods forresidual stress measurement显示文摘 | RUUD C | 1982 | NDT&E1982，15，1： | 1 |
| 4 | Structuring inβ - Si- tosterol + γ-Oryzanol -based emulsion gels during vari- ousstages of a temperature cycle 显示文摘 | Bot A Ruud den Adel Regkos C | 2011 | Food Hydrocolloids2011，25，4： | 1 |
| 5 | On three - dimensional surface reconstruction methods显示文摘 | Bolle Ruud M Vemuri Baba C | 1991 | IEEE Transaction Patent Analogy Machine International1991，13，1： | 1 |
| 6 | Determination of daminozide in apples and apple leaves by liquid chromatographymass spectrometry显示文摘 | HANS G J M RUUD C J V D ROB J V | 1999 | Journal of Chromatography A1999，833，1： | 1 |
| 7 | Fiber-optic oxygen sensor using molybdenum chloride cluster luminescence显示文摘 | Chosh R N Baker G L Ruud C | 1999 | Applied Physics Letters1999，75，19： | 1 |
| 8 | Monitoring and evaluation of the environmental dissipation of the marine antifoulant 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) in a Danish Harbor显示文摘 | Ruud J C A Freek A Bert van H | 2004 | Chemosphere2004，57，： | 1 |
| 9 | Thrombotic effects of asparaginase in two acute lymphoblastic leukemia protocols (NOPHO ALL-1992 versus NOPHO ALL-2000) : a single-institution study显示文摘 | Ruud E Holmstrom H de Lange C | 2006 | Pediatr Hematol Oncol2006，23，3： | 1 |
| 10 | Determination of polar organophosphorus pestieides in vegetables and fruits using liquid chromatography with tauden mass spectrometry: selection of extraction solvent 显示文摘 | Hans G J Mol Ruud C J van Dam Steijgcr O M | 2003 | Journal of Chromatorgraphy A2003，1015，12： | 1 |
| 11 | Preparation and implementation of seven ecological compensation plans for dutch highways显示文摘 | RUUD C | 2002 | Environmental Management2002，29，6： | 1 |
| 12 | Mass flow rate measurements in gas-liquid flows by means of a venturi or orifice plate coupled to a void fraction sensor显示文摘 | JORGE L G O JúLIO C P RUUD V | | 0，，： | 1 |
| 13 | Relationships between residual stress,microstructure and mechanical properties of electron beam-physical vapor deposition thermal barrier coatings显示文摘 | Johnson C A Ruud J A Bruce R | 1998 | Surface and Coatings Technology1998，，13： | 1 |
| 14 | Bayesian recognition of local 3-D shape by approximating image intensity functions with quadric polynomials显示文摘 | Ruud M B David B C | 1984 | IEEE Transactions on Pattern Analysis and Machine Intelligence1984，6，4： | 1 |
| 15 | A review of selected non-destructive methods for residual stress measurement显示文摘 | RUUD C O | 1982 | NDT International1982，15，1： | 1 |
| 16 | Experimental investigation of the machining induced residual stress tensor under mechani~ cal loading 显示文摘 | Fu W Cohen P H Ruud C O | 2009 | Journal of Manufacturing Processes2009，11，2： | 1 |
| 17 | Determination of polar organophos- phorus pesticides in aqueous samples by direct injection using liquid chromatography - tandem mass spectrometry 显示文摘 | BennoA Ruud C Rob J | 2001 | J Chromatogr A2001，918，1： | 1 |
| 18 | Preparation and characterrization of a bis(silsesquioxane)tungsten corn- plex显示文摘 | Mark C Ruud H M Herold | 1997 | Chemical Communication1997，，： | 1 |
| 19 | A model for foam formation,stability,and breakdown in glass-melting furnaces 显示文摘 | John van der Schaaf Ruud G C Beerkens | 2006 | Journal of Colloidand Interface Science2006，295，： | 1 |
| 20 | Fibrils of -y - oryzanol + 13 - sitosterol in edible oil organogels 显示文摘 | Bot A Ruud den Adel Eli C Roijers | 2008 | Journal of American Oil Chemists'' Society2008，85，： | 1 |
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