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4376篇 您的检索式:作者名="Fu W"
    题名 作者 年代 出处 被引量
1Effective treatment of manganese-induced occupational parkinsonism with p-aminosalicylic acid: a case of 17-year follow-up study.显示文摘Jiang YM Mo XA Du FQ Fu X Zhu XY Gao HY Xie JL Liao FL Pira E Zheng W 2006中国生物学文摘2006,20,8:23
2SOX11可表达于Cyclin D1阴性母细胞样套细胞淋巴瘤显示文摘近期的研究表明SOX11表达有助于套细胞淋巴瘤(MCL)的诊断,包括具有典型形态学改变的cyclin D1阴性MCL。本文作者探讨了SOX11在B细胞非霍奇金淋巴瘤(B-NHL)某些亚型中的表达模式及其特异性,并将其作为免疫表型特征分析cyclin D1阴性的母细胞样MCL(该组病例系首次报道)的识别价值。Zeng W Fu K Quintanilla-Fend L 孙琦(摘译) 樊祥山(审校) 2012临床与实验病理学杂志2012,28,2:14
3Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor显示文摘SRC-3/AIB1 (在乳癌 1 的类固醇受体激活剂 3/amplified ) 是在癌症病人贡献药抵抗和差的没有疾病的幸存的发展的真 oncogene。Autophagy 也是让肿瘤 suppressor 工作的重要房间死亡机制。在这研究,我们识别了巨噬细胞移植禁止的因素(MIF ) 作为 SRC-3 的新奇目标基因并且在房间幸存表明了它的重要性。明确地,我们证明 MIF 是 autophagic 房间死亡的强壮的 suppressor。我们进一步证明接着, MIF 的抑制导致了 autophagic 房间死亡,提高了 chemosensitivity 并且禁止了在一个异种皮移植老鼠 tumorigenesis 模型的 tumorigenesis。我们的学习证明 MIF 表示的那条规定和 autophagic 房间死亡的抑制是 SRC-3 由贡献增加的 chemoresistance 和 tumorigenicity 的有势力机制。Mei-Yi Wu Junjiang Fu Jianming Xu Bert W O'MaUey Ray-Chang Wu 2012Cell Research2012,22,6:12
4An epigenomic approach to therapy for tamoxifen-resistant breast cancer显示文摘Tamoxifen 是为雌激素受体 alpha 的前线治疗(ERα) 在绝经前的女人的积极的胸肿瘤。然而,到 tamoxifen 的抵抗发生在许多病人。嗯仍然与获得的 tamoxifen 抵抗在乳癌房间的生长起一个关键作用,建议那 ERα为治疗仍然是一个有效目标 tamoxifen 抵抗(Tam-R ) 乳癌。以识别 ERα 的新奇管理者;发信号,通过对 histone 甲基修饰词的一幅小规模的 siRNA 屏幕,我们发现了 WHSC1, histone H3K36 methyltransferase, ERα 的一个积极管理者;在乳癌房间发信号。我们证明 WHSC1 被招募到 ERα由 BET 蛋白质 BRD3/4 的基因,并且便于 ERα基因表示。小分子的赌注蛋白质禁止者 JQ1 potently 压制了经典 ERα发信号的小径和在文化的 Tam-R 乳癌房间的生长。用一个 Tam-R 乳癌异种皮移植老鼠模型,我们与 JQ1 和 ER degrader fulvestrant 由 JQ1 和联合治疗的强壮的长持续的效果在 vivo 反胸癌症活动示威了。一起拿,我们提供 epigenomic 蛋白质 BRD3/4 和 WHSC1 是雌激素受体发信号的必要管理者并且是为 Tam-R 乳癌的治疗的新奇治疗学的目标的证据。Qin Feng Zheng Zhang Martin J Shea Chad J Creighton Cristian Coarfa Susan G Hilsenbeck Rainer Lanz Bin He Lei Wang Xiaoyong Fu Agostina Nardone Yongcheng Song James Bradner Nicholas Mitsiades Constantine S Mitsiades C Kent Osborne Rachel Schiff Bert W O'Malley 2014Cell Research2014,24,7:10
5Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels显示文摘Fu H Li W Lao Y Luo J Lee NT Kan KK Tsang HW Tsim KW Pang Y Li Z Chang DC Li M Han Y 2006中国生物学文摘2006,20,10:10
6QUANTUM MECHANICAL MODEL AND SIMULATION OF GaAs/AlGaAs QUANTUM WELL INFRARED PHOTODETECTOR-Ⅱ ELECTRICAL ASPECTS显示文摘A complete quantum mechanical model for GaAs/AlGaAs quantum well infrared photodetectors(QWIPs) was presented. The photocurrent was investigated by the optical transition(absorption coefficient)between the ground state and the excited states due to the nonzero component of the radiation field along the sample growth direction. By studying the inter diffusion of the Al atoms across the GaAs/AlGaAs heterointer faces, the mobility of the drift diffusion carriers in the excited states was calculated. As a result, the measurement results of the dark current and the photocurrent spectra are explained theoretically.Fu Y Willander M LU W 2002红外与毫米波学报2002,21,6:4
7伴有浆细胞分化的套细胞淋巴瘤显示文摘Young K H Chan W C Fu K 黄文斌(摘译) 2006临床与实验病理学杂志2006,22,5:2
8鱼、蛋、牛奶、坚果、蔬菜和水果摄入量大,以及低盐膳食模式与高血压的患病率和控制率相关显示文摘食物对高血压患病率和控制率的影响尚不清晰。本文旨在中国人群中调查鱼、蛋、牛奶、坚果、蔬菜和水果摄入量大以及低盐膳食模式是否与高血压有关。方法:从2012年9月到2014年12月共招募15303名受试者进行病例对照研究,分为高血压组(n=1604)和正常血压组(n=13660),其中高血压组又分为血压控制亚组(n=397)和血压未控制亚组(n=1207)。收集过去1 年里每周平均鱼、蛋、牛奶、坚果、蔬菜、水果和盐摄入量数据。鱼、蛋、牛奶、坚果、蔬菜、水果和盐的平均摄入量分别为117、150、35、20、2100、300和58g/周。Yu G Fu H Huang W Zhang N Deng D Li G Lei H 2019中华高血压杂志2019,27,5:2
9Coronary bifurcation angle from 3-D predicts clinical outcomes after stenting bifurcation lesions显示文摘CHEN Shao-liang Teguh Santoso ZHANG Jun-jie YE Fei XU Ya-wei FU Qiang KAN Jing Chitprapai Paiboon ZHOU Yong DING Shi-qing Tak W Kwan 2012Chinese Medical Journal2012,,12:2
10An Approximation of the Customer Waiting Time for Online Restaurants Owning Delivery System显示文摘Online restaurants, which receive online orders and deliver food directly to the customer’s residence, are becoming increasingly popular. To be successful, online restaurants need to provide reliable and prompt deliveries. Careful design of the meal preparation and order delivery systems is needed to avoid excessive cust omer waiting time bet ween ordering and delivery. This paper considers the meal preparation and delivery processes simultaneously to approximate average customer waiting time for deliveries. The authors first discuss the system performance with one cook and unit-capacity delivery vehicles, using an M/G/1queue and a GI/G/1queue. Numerical experiments show that our approximation can adequately describe real waiting times. Then, series queues with multiple cooks and multi-capacity delivery vehicles, e.g., an M/G/n queue and a GI/Gn/1 queue, are examined. Results show that except for situations with a large meal preparation time and a small vehicle capacity, compared with the result of simulation, the approximation in this paper is acceptable with a deviation of less than 20%. The marginal decrease in waiting time associated with hiring more vehicles is est.imated under different meal preparation speeds, sizes of service area and vehicle capacities.ZHANG Tianhua ZHAO Fu ZHANG Juliang MENDIS Gamini RU Yihong SUTHERLADN John W 2019Journal of Systems Science & Complexity2019,32,3:2
11The application of linear motor in high-speed precision cylindrical grinding显示文摘Fu D W Wu Y H Ai Q L 2001Key Engineering Materials2001,,:2
12Interoperability of Design Intent in Integrated Product and Process Design显示文摘Concurrent engineering is currently an overwhelming t rend in product development since it takes the down-stream product development issues and product life-cycle issues into consideration in up-front design pro cess. At this stage, evaluation, verification and validation of design concepts and design schemes is critical to the right-to-market product development. I dentification and extraction of design intent from the part digital mock-ups in different data formats and created in different CAD systems for DFX considerati on, evaluation, verification, and validation is crucial too. Traditionally, fro m manufacturing point of view, feature identification and extraction is to get t he features and feature-related information for manufacturing planning and inte gration. Presently, from the viewpoint of product development and product servi ce life cycle, design intent identification and extraction is to get all the des ign-related information for DFX consideration in early design stage, such as de sign for assembly, design for service, design for tooling, design for functional ity and design for environment etc. Therefore, how to successfully extract desi gn intent such as design and machining features and design-related information from the prototyping digital mock-ups created by different CAD systems for DFX consideration in upstream design stage is a very useful topic in integrated prod uct and process design and development. Presently, there are heterogeneous CAD systems in the market and the interoperat ion among the different CAD systems is indispensable. The interoperability of d ifferent CAD systems is by way of data exchanged technology such as STEP and IGE S. The critical weakness of this interoperation technology is that much of the design intent is lost in the interoperation process. Once the product digital m ock-ups is exchanged via data exchange technology such as IGES or STEP, the des ign intent including the dimension-driven design features and other attributes embedded in the part model are lost in the data translation process. Models rea d out of CAD systems come into other systems as featureless chunks of geometry e ntities. Obviously, the interoperation technology does not satisfy the industry need. It has been reported that this poor interoperation technology, which pro vides poor CAD models in neutral-format geometry had cost the automobile indust ry alone $1 billon per year. Fortunately, some researchers have been aware of t he criticality of this since only the United States industry spends billons of d ollars as a result of poor interoperability between computer-aided engineering software tools. In the past, product development was often done within a single company by co-located design team. In more recent years, there has been a busi ness paradigm shift in product development as the product development is being d one more often by geographically and temporally distributed design teams. There is a high level of outsourcing, not only of manufacturing but also of actual pr oduct development effort. Besides, product development across companies, and ev en within a single company, is often done within a heterogeneous software tool e nvironment. How to improve the interoperability of design intent created in het erogeneous software tool environment geographically has become a critical issue in next-generation product development system. Design intent in this research is defined as the outcome of design process. Des ign process goes from the identification of needs to satisfaction of that needs. Design intent satisfies this kind of needs. In this research, design intent i s created in a CAD system and embedded in part CAD model. The detailed design i ntent here includes design and manufacturing features and the feature-relat ed information such as feature parameters, feature relationships and some relate d characteristics such as associativity. Interoperability refers to the ability to share and communicate in the heterogeneous environment or heterogeneous softM W Fu W F Lu A Y C Nee S K Ong 2002厦门大学学报(自然科学版)2002,41,S1:2
13QUANTUM MECHANICAL MODEL AND SIMULATION OF GaAs/AlGaAs QUANTUM WELL INFRARED PHOTO-DETECTOR-ⅠOPTICAL ASPECTS显示文摘A complete quantum mechanical model for GaAs?AlGaAs quantum well infrared photodetectors(QWIPs) is presented here. The model consisted of four parts: (1) Starting with the description of the electromagnetic field of the infrared radiation in the QWIP, effective component of the vector potential <| A z |> along the QWIP growth direction ( z axis) due to the optical diffraction grating was calculated. (2) From the wave transmissions and the occupations of the electronic states, it was discussed that the dark current in the QWIP is determined by the drift diffusion current of carriers thermally excited from the ground sublevel in the quantum well to extended states above the barrier. (3) The photocurrent was investigated by the optical transition (absorption coefficient between the ground state to excited states due to the nonzero <| A z |> ). (4) By studying the inter diffusion of the Al atoms across the GaAs?AlGaAs heterointerfaces,the mobility of the drift diffusion carriers in the excited states was calculated, so the measurement results of the dark current and photocurrent spectra can be explained theoretically. With the complete quantum mechanical descriptions of (1 4), QWIP device design and optimization are possible.Fu Y Willander M Li Ning Lu W 2002红外与毫米波学报2002,21,5:2
14Role and relevance of polarity and hindrance of vinyl monomers in graft copolymerization onto potato starch显示文摘Fu Z S Liang W D Yang A M 2002J Appl Polym Sci2002,85,4:2
15Effects of the phase-separated melt on crystallization behavior and morphology in short chain branched metallocene polyethylenes显示文摘Fu Q Chiu F C McCreight K W Guo M Tseng W W Cheng S Z Keating M Y Hsieh E T and DesLauriers P J 0,,:2
16The Multi-staged Formation Process of Titanium Oxide Nanotubes and its Thermal Stability 显示文摘Li W Fu T Xie F 2007Materials Letters2007,61,:1
17Defunctionalization of functionalized carbon nanotubes显示文摘Fu K Huang W J Lin Y 2001Nano Letters2001,1,8:1
18The veterinary antibiotic oxytetracycline and Cu influence functional diversity of the soil microbial community 显示文摘KONG W D ZHU Y G FU B J 2006Environmental Pollution2006,143,:1
19Endoascular therapy for stanford type B aortic dissection in 102 cases显示文摘Fu W Shi Y Wang Y 2005Asian J Surg2005,28,4:1
20Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway显示文摘Chen CJ Yu W Fu YC 2009Biochem Biophys Res Commun2009,378,3:1
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