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1Serum and ascites levels of macrophage migration inhibitory factor, TNF-α and IL-6 in patients with chronic virus hepatitis B and hepatitis cirrhosis显示文摘Objective: To study the potential role of macrophagemigration inhibitory factor (MIF), tumor necrosisfactor-α (TNF-α) and interleukin-6 (IL-6) in thedevelopment of chronic virus hepatitis B (CH) andhepatitis cirrhosis (HC).Methods: The serum concentrations of MIF, TNF-αand IL-6 in 18 patients with chronic virus hepatitis Band in 14 patients with hepatitis cirrhosis without as-citic fluid, and the serum and ascites cytokine con-centrations in 22 HC patients with ascitic fluid weredetected by enzyme linked immunity sorbed assay.Results: The cytokine concentrations of the patientswere significantly higher than those of the controls.The serum levels of MIF, TNF-α and IL-6 of the 22patients with ascitic fluid were higer than those of 14HC patients without ascites. In the 18 patients withCH, the serum cytokine concentrations were the low-est. The serum cytokine concentrations of the 22 HCpatients with ascites were significantly higher thanthose of the 14 HC patients without ascites (P<0. 01). Their serum cytokine concentrations were sig-nificantly higher than those in the 18 patients withCH (P<0. 01). The concentration of IL-6 in asciteswas the highest among all the groups. The serum le-vels of MIF, TNF-α and IL-6 are correlated with al-anine aminotransferase (ALT) in the patients withCH, but not in those with HC with or without asci-tes.Conclusions: These results indicated that MIF, TNF-α and IL-6 may participate in the pathologicalprocess of CH and cirrhosis, that IL-6 seems to playan important role in ascites formation, and that se-rum levels of MIF, TNF-α and IL-6 appear to reflectthe severity of tissue injury in HBV disease.Wei Zhang Bei Yue Gui-Qiang Wang Shu-Lan Lu the Department of Infectious Dispeases, Ruijing Hospital, Shanghai Second Medical University, Shanghai 200025, China Department of Intectious Diseases, Second Affiliated Hospital, Harbin Medical University, Harbin 150086, China 2002Hepatobiliary & Pancreatic Diseases International2002,1,4:18
2Fengyun Meteorological Satellite Products for Earth System Science Applications显示文摘Following the progress of satellite data assimilation in the 1990s, the combination of meteorological satellites and numerical models has changed the way scientists understand the earth. With the evolution of numerical weather prediction models and earth system models, meteorological satellites will play a more important role in earth sciences in the future. As part of the space-based infrastructure, the Fengyun (FY) meteorological satellites have contributed to earth science sustainability studies through an open data policy and stable data quality since the first launch of the FY-1A satellite in 1988. The capability of earth system monitoring was greatly enhanced after the second-generation polar orbiting FY-3 satellites and geostationary orbiting FY-4 satellites were developed. Meanwhile, the quality of the products generated from the FY-3 and FY-4 satellites is comparable to the well-known MODIS products. FY satellite data has been utilized broadly in weather forecasting, climate and climate change investigations, environmental disaster monitoring, etc. This article reviews the instruments mounted on the FY satellites. Sensor-dependent level 1 products (radiance data) and inversion algorithm-dependent level 2 products (geophysical parameters) are introduced. As an example, some typical geophysical parameters, such as wildfires, lightning, vegetation indices, aerosol products, soil moisture, and precipitation estimation have been demonstrated and validated by in-situ observations and other well-known satellite products. To help users access the FY products, a set of data sharing systems has been developed and operated. The newly developed data sharing system based on cloud technology has been illustrated to improve the efficiency of data delivery.Di XIAN Peng ZHANG Ling GAO Ruijing SUN Haizhen ZHANG Xu JIA 2021Advances in Atmospheric Sciences2021,38,8:14
3Formation of Natural Bitumen and its Implication for Oil/gas Prospect in Dabashan Foreland显示文摘Natural bitumen is the evolutionary residue of hydrocarbon of sedimentary organic matter.Several kinds of bitumen with different occurrences,including bitumen in source rock,migration bitumen filled in fault,oil-bed bitumen and paleo-reservoir bitumen,are distributed widely in the Dabashan foreland.These kinds of bitumen represent the process of oil/gas formation,migration and accumulation in the region.Bitumen in source rock filled in fractures and stylolite and experienced deformation simultaneously together with source rock themselves.It indicated that oil/gas generation and expelling from source rock occurred under normal buried thermal conditions during prototype basin evolution stages prior to orogeny.Occurrences of bitumen in source rock indicated that paleo-reservoir formation conditions existed in the Dabashan foreland.Migration bitumen being widespread in the fault revealed that the fault was the main channel for oil/gas migration,which occurred synchronously with Jurassic foreland deformation.Oil-bed bitumen was the kind of pyrolysis bitumen that distributed in solution pores of reservoir rock in the Dabashan foreland depression,the northeastern Sichuan Basin.Geochemistry of oil-bed bitumen indicated that natural gas that accumulated in the Dabashan foreland depression formed from liquid hydrocarbon by pyrolysis process.However,paleo-reservior bitumen in the Dabashan forleland was the kind of degradation bitumen that formed from liquid hydrocarbon within the paleo-reservior by oxidation,alteration and other secondary changes due to paleo-reservior damage during tectonics in the Dabashan foreland.In combination with the tectonic evolution of the Dabashan foreland,it is proposed that the oil/gas generated,migrated and accumulated to form the paleo-reservoir during the Triassic Indosinian tectonic movement.Jurassic collision orogeny,the Yanshan tectonic movement,led to intracontinental orogeny of the Dabashan area accompanied by geofluid expelling and paleo-reservoir damage in the Dabashan foreland.The present work proposed that there is liquid hydrocarbon exploration potential in the Dabashan foreland,while there are prospects for the existence of natural gas in the Dabashan foreland depression.LI Rongxi DONG Shuwen ZHANG Xue ZHU Ruijing 2012Acta Geologica Sinica(English Edition)2012,86,2:7
4Estrogen upregulates MICA/B expression in human non-small cell lung cancer through the regulation of ADAM17显示文摘雌激素涉及支持肺癌症房间分割和转移。云母和 MICB 为 NKG2D 作为 ligands 工作,在生来的杀手(NK ) 上表示的重要 immunoreceptor 房间。然而,雌激素是否调整 MICA/B 表示并且影响肿瘤免疫者逃跑,仍然保持未知。在这研究,我们测量了非小的房间肺癌症(NSCLC ) 房间线与雌激素对待的云母, MICB 和 ADAM17in 的 mRNA 层次。LTEP-a2 和 A549 上的 MICA/B 的表面表示用流动 cytometry 被检测。我们证明 mRNA 和在肺腺癌房间线的 MICA/B 的能分泌的蛋白质层次是由 estradiol 的 upregulated。Estradiol 提高了 ADAM17 的表示,它与 MICA/B 的分泌物被联系。MICA/B downregulated 的这分泌物 NK92 房间的表面上的 NKG2D 受体并且损害了 NK 房间的细胞毒素的活动。Estradiol 提高了 ADAM17 的表示,它与 MICA/B 的分泌物被联系。而且,在 estradiol 和云母的表示的集中之间的重要关联在 NSCLC 病人的肿瘤纸巾被发现。因此,我们断定雌激素能通过 ADAM17 调整 MICA/B 的表示和分泌物,它帮助肺癌症房间逃离调停 NKG2D 的有免疫力的监视。Jing Ren Yunzhong Nie Mingming Lv Sunan Shen Ruijing Tang Yujun Xu Yayi Hou Shuli Zhao Tingting Wang 2015Cellular & Molecular Immunology2015,12,6:6
5EBV-Induced Human CD8^+ NKT Cells Synergise CD4^+ NKT Cells Suppressing EBV-Associated Tumours upon Induction of Thl-Bias显示文摘Wei Xiao Li Li Rui Zhou Ruijing Xiao Yujuan Wang Xiang Ji Mengjun Wu Lan Wang Wei Huang Xiaoling Zheng Xinti Tan Lang Chen Tao Xiong Jie Xiong Youxin Jin Jinquan Tan Yuling He 2009Cellular & Molecular Immunology2009,6,5:5
6Pyrrolidine dithiocarbamate protects pancreatic β-cells from oxidative damage through regulation of FoxO1 activity in type 2 diabetes rats显示文摘Pyrrolidine dithiocarbamate (PDTC ) 罐头降低血葡萄糖水平并且在糖尿病的 rats.However 改进胰岛素敏感,在糖尿病的老鼠位于 PDTC 治疗的这效果下面的机制仍然保持不明确。在这研究,我们 PDTC 与 experimentaltype 在老鼠对胰腺的小岛房间的氧化损坏由授与保护的 evaluatedthe 机制 2 糖尿病 mellitus (DM ) 。在老鼠的 DM 被伴有单个 intraperitoneal (i.p ) 的长期的高脂肪的饮食得到 streptozotocin 的低剂量的注射。在 PDTC (50 mg/kg/day i.p ) 的一个 7 天的政府以后,血 glucoselevels 被测量,胰腺的纸巾为各种各样的生物化学、酶的 activitiesusing immunohistochemistry, immunofluorescence,和西方的污点技术的决心是镇定的。apoptotic 的百分比胰腺的小岛房间被流动 cytometry 检测。结果证明糖尿病的老鼠提高了血葡萄糖层次和 insulinresistance,随 malondialdehyde 内容, nitrotyrosine 生产,和可诱导的氮的 oxidesynthase 表示的增加伴随了。在 superoxide dismutase 和谷胱甘肽 peroxidase 活动的减少也在 DM 老鼠被观察,与提高的房间 apoptosis 达到顶点。PDTC 处理显著地减少了氧化损坏和房间 apoptosis,并且也通过下面调整的 FoxO1 acetylation 和建议的起来调整的原子 PDX-1 level.These 数据增加了胰岛素生产那 PDTC 能保护小岛房间免受氧化损坏的伤害并且在一个 DM 老鼠模型通过 regulationof PDX-1 和 FoxO1 改进胰岛素生产。Haiyan Ding Tienian Zhu Xiaomei Yin Jiankun Liu Lizhong Zhang Michel Bemier Ruijing Zhao 2014Acta Biochimica et Biophysica Sinica2014,46,7:4
7Research on a New Process of Preparation for Nano-SiO_2 with High Activity and Mesopores显示文摘With substitution of La by Tb in (La1-xTbx)0.67Sr0.33MnO3, the room temperature magnetoresistance AR/R0 drops at first, then undergoes an increase near x≈0.1, and finally drops again. The value of room temperature magnetoresistance at a field H=12 kOe for (La0.9Tb0.1)0.67Sr0.33MnO3 is -3.56%. The enhancement of the room temperature magnetoresistance induced by an appropriate Tb substitution in (La1-xTbx)0.67Sr0.33MnO3 is correlated with the shifts of the Curie temperature and metal-insulator temperature to near room temperature. The drop of the room temperature magnetoresistance at large Tb doping-contents may be due to its lower TC and TMI far from the room temperature.Ruijing ZHANG Ke YANG Tianyng XIONG Institute of Metal Resarch,Chinese Academy of Sciences,Shenyang 110016, China 2004Journal of Materials Science & Technology2004,20,3:4
8Adaptive Pseudo Inverse Control for a Class of Nonlinear Asymmetric and Saturated Nonlinear Hysteretic Systems显示文摘This paper aims at eliminating the asymmetric and saturated hysteresis nonlinearities by designing hysteresis pseudo inverse compensator and robust adaptive dynamic surface control(DSC)scheme.The'pseudo inverse'means that an on-line calculation mechanism of approximate control signal is developed by applying a searching method to the designed temporary control signal where the true control signal is included.The main contributions are summarized as:1)to our best knowledge,it is the first time to compensate the asymmetric and saturated hysteresis by using hysteresis pseudo inverse compensator because the construction of the true saturated-type hysteresis inverse model is very difficult;2)by designing the saturated-type hysteresis pseudo inverse compensator,the construction of true explicit hysteresis inverse and the identifications of its corresponding unknown parameters are not required when dealing with the saturated-type hysteresis;3)by combining DSC technique with the tracking error transformed function,the'explosion of complexity'problem in backstepping method is overcome and the prespecified tracking performance is achieved.Analysis of stability and experimental results on the hardware-inloop platform illustrate the effectiveness of the proposed adaptive pseudo inverse control scheme.Xiuyu Zhang Ruijing Jing Zhiwei Li Zhi Li Xinkai Chen Chun-Yi Su 2021IEEE/CAA Journal of Automatica Sinica2021,8,4:4
9Recovery of neodymium,dysprosium,and cobalt from NdFeB magnet leachate using an unsymmetrical dialkylphosphinic acid extractant,INET-3显示文摘Rare earths (REs) and Co are critical strategic resources.Their recovery is crucial for ensuring that their supplies are adequate and for reducing environmental pollution.End-of-life NdFeB magnets are important secondary RE sources.The separation of Dy,Nd,and Co from NdFeB leachate using a relatively new extractant (2,3-dimethylbutyl)(2,4,4’-trimethylpentyl)phosphinic acid (INET-3),was investigated in this study.The separation parameters,such as equilibrium pH,phase ratio,INET-3 concentration,and number of counter-current extraction stages,were optimised.The results show that INET-3 can separate Dy,Nd,and Co efficiently.For the preferential extraction of Dy from synthetic iron-free NdFeB leachate,the optimum equilibrium pH is 2.60.Under this condition,separation of Dy from the leachate requires four counter-current extraction stages at A/O (volume ratio of aqueous to organic)=1:2.This is demonstrated by a simulated four-stage counter-current extraction process.At equilibrium pH=2.52and A/O=1:2,98%of Dy is recovered with 95%purity.As to the subsequent separation of Nd from the leachate,nearly 100%is recovered with 99%purity through a simulated three-stage counter-current extraction process at equilibrium pH=5.33 and A/O=1:1.Approximately 95%of Co remains in the raffinate with 99.98%purity.Zhengyu Liu a Jiaming Wu a Xinyu Liu Wen Wanga Ziwei Li Ruijing Xu Yue Ding Junlian Wang 2020Journal of Rare Earths2020,38,10:3
10The flux-E_p relation within GRB060218 in comparison with typical GRB pulses显示文摘The prompt gamma-ray/X-ray emission of gamma-ray burst(GRB) 060218 was simultaneously observed by the Burst Alert Telescope(BAT) and X-ray Telescope(XRT) onboard Swift.Its peak energy of the joint νfν spectrum(Ep) clearly evolves with time from tens of keV to-1 keV,crossing both the BAT and XRT bands.The best fit yields log Ep=(4.61± 0.23)+(-1.29±0.08) log t,with a correlation coefficient of 0.98 and a chance probability of p<10-4.We derive its bolometric flux(F)in the 0.01-10 4 keV band,and find that its F-Ep relation,with a power-law index of 0.37,is much shallower than that observed in typical GRB pulses.Discussion of this shallowness is presented.DONG Wei,LIANG EnWei & LU RuiJing Physical Science & Technology College,Guangxi University,Nanning 530004,China 2010Science China(Physics,Mechanics & Astronomy)2010,53,S1:3
11Environmental taxation and regional inequality in China显示文摘In order to combat environmental pollution, China enacted the Environmental Protection Tax Law in early 2018. Yet the impacts of the environmental tax on individual regions with different socioeconomic statuses, which are crucial for social justice and public acceptance, remain unclear. Based on a MultiRegional Input-Output(MRIO) table and a nationally regulated tax payment calculation method, this study analyzes the distributional impacts of an environmental tax based upon province’s consumption from both inter-provincial and rural-urban aspects. The national tax revenue based on the current levy mechanism is estimated to be only one seventh of the economic loss from premature mortality caused by ambient particulate matter(PM2.5). The taxation may slightly alleviate urban-rural inequality but may not be helpful with reducing inter-provincial inequality. We further analyze two alternative levy mechanisms. If each province imposes taxes to products it consumes(rather than produces, as in the current mechanism), with the tax rate linearly dependent on its per capita consumption expenditure, this would moderately increase the national tax revenue and significantly reduce inter-provincial inequality.To better compensate for the economic costs of air pollution and reduce regional inequality, it would be beneficial to increase the tax rate nationwide and implement a levy mechanism based on provincially differentiated levels of consumption and economic status.Jingxu Wang Jintai Lin Kuishuang Feng Peng Liu Mingxi Du Ruijing Ni Lulu Chen Hao Kong Hongjian Weng Mengyao Liu Giovanni Baiocchi Yu Zhao Zhifu Mi Jing Cao Klaus Hubacek 2019Science Bulletin2019,64,22:3
12Template-directed Synthesis of Three Metal Oxalates via 4-Connected Building Units显示文摘TIAN Ruijing WANG Fuxiang DU Chunyu FENG Lijuan LIU Ying ZHANG Cailing PAN Qinhe 2014Chemical Research in Chinese Universities2014,30,6:3
13WONCA研究论文摘要汇编——癌症晚期患者在家中临终前的症状及其难以忍受的程度与性质:基层医疗研究展望显示文摘背景基层医生可以在家中为癌症患者提供以缓解症状为目的的医疗服务。以荷兰为例,在家去世的癌症患者(占全部癌症患者的45%)大约每7人中就有1人在离世过程中表现出难以忍受的痛苦。本试验将从接受基层医疗服务的临终癌症患者的常见症状分布,症状及其难以忍受程度的强弱、随病程进展的变化情况及其性质之间的关系两个方面展开研究。方法 44名全科医生3年中不断选取预期寿命〈6个月的癌症患者。根据《痛苦状况-V》(SOS-V),每隔2个月对69种症状在选取患者中表现出的强弱及难以忍受程度进行量化。同样按照5分评价的方法〔从1分(一点不痛苦)到5分(不能更痛苦)〕,对总体症状难以忍受的程度也进行量化。Ruijs CD Kerkhof AJ van der Wal G 周淑新 2014中国全科医学2014,17,17:2
14Fast synthesis of monodisperse TiO_2 submicrospheres via a modified sol-gel approach显示文摘Monodisperse titania glycolate submicrospheres were synthesized by a modified sol-gel route, in which ultrasonic treatment was introduced to improve the reaction efficiency. The as-prepared products were characterized by means of Fourier transform infrared spectrum (FT-IR), transmission electron microscopy (TEM), powder X-ray diffraction (XRD), and scanning electron microscopy (SEM). The results indicate that the as-prepared products are titania glycolate submicrospheres with diameters of 230-330 nm. The average particle diameter is estimated to be about 280 nm. Ultrasonic treatment has an important influence on the morphology of the produced titania glycolates. After calcination at 450°C for 2 h, these titania glycolates were completely converted into anatase TiO2. The morphology of TiO2 particles was well reserved during the calcination process except for a reduction of 18% in the average particle size.WANG Hong'en LI Bo YAN Zaoxuea LU Zhouguang CHENG Ruijing QIAN Donga 2008Rare Metals2008,27,1:2
15FLNa negatively regulated proliferation and metastasis in lung adenocarcinoma A549 cells via suppression of EGFR显示文摘Filamin A (FLNa ) 是无所不在地表示的细胞质的蛋白质,它 24 次象 Ig 一样重复跟随的一个 N 终端肌动朊绑定领域(ABD ) 创作。FLNa 作为连接 transmembrane 受体的细胞骨架蛋白质工作,包括 integrins,到 F 肌动朊并且用作发信号的中介。最近的研究作为与超过 90 蛋白质交往并且在细胞的发信号的 transduction 起重要作用的支架蛋白质识别了 FLNa。在人的 FLNa 基因的变化或缺点被显示了引起众多的发展缺点。而且, FLNa 的异常表示在许多癌症被观察了例如甲状旁腺的肿瘤,颈的癌症,和乳癌。然而,它在肺腺癌的角色很少被讨论了。在现在的学习,我们的在里面 vitro 并且在 vivo,研究证明在肺癌症房间线 A549 房间的那 silencing FLNa 表情由提高表皮的生长因素受体和英皇家空军之阶级最低之兵发信号小径的激活支持了 A549 房间的增长,移植,和侵略。这些结果在肺癌症和揭开的新奇机制使 FLNa 的新奇功能清楚些,这些结果为肺腺癌为预言和治疗提供了可能的目标。Yuna Zhang Tienian Zhu Jingpu Liu Jiankun Liu Dongmei Gao Tongyi Su Ruijing Zhao 2018Acta Biochimica et Biophysica Sinica2018,50,2:2
16Comparison of Four Forward Models for Breast Imaging in Ultrasound Computed Tomography显示文摘Ultrasound computed tomography(USCT)is considered to have great potential for breast cancer screening.Compared with ray-based methods,Waveform inversion(WI)methods obtain high spatial resolution images because they consider higher-order diffraction effects.For the WI method,considering more properties of the medium in a forward model can estimate more accurate images.However,longer reconstruction time is required.Therefore,to reduce the reconstruction time,three hypotheses are set in this work to develop the medium under different conditions.We compare the reconstructed images using the four forward models to analyze the effects of the various considered medium properties,which include the sound speed,density of the medium,acoustic absorption and dispersion.To reduce the difficulty of hardware manufacturing,a square border ultrasonic transducer array is adopted in the USCT data acquisition system.Penalized leastsquares optimization problems are constructed to obtain numerical solutions of the sound speed and bulk modulus distributions.The reconstruction of the bulk modulus makes the reconstructed sound speed images more accurate.Computer simulations are conducted to compare reconstructed images using the four forward models under different noise conditions.A numerical breast phantom is used to evaluate the performance.The results suggest that for breast imaging,the forward model(which only considers the heterogeneous sound speed)is a compromise option between image accuracy and computational time.LI Ruijing CHEN Houjin PENG Yahui LI Jupeng 2019Chinese Journal of Electronics2019,28,4:2
17Enabling Mg metal anodes rechargeable in conventional electrolytes by fast ionic transport interphase显示文摘Rechargeable magnesium batteries have received extensive attention as the Mg anodes possess twice the volumetric capacity of their lithium counterparts and are dendrite-free.However:Mg anodes sufferfrom surface passivation film in most glyme-based conventional electrolytes;leading to irreversible plating/stripping behavior of Mg.Here we report a facile and safe method to obtain a modified Mg metal anode with a Sn-based artificial layer via ion-exchange and alloying reactions.In the artificial coating layer,Mg2Sn alloy composites offer a channel for fast ion transport and insulating MgCl2/SnCb bestows the necessary potential gradient to prevent deposition on the surface.Significant improved ion conductivity of the solid electrolyte interfaces and decreased overpotential of Mg symmetric cells in Mg(TFSI)2/DME electrolyte are obtained.The coated Mg anodes can sustain a stable plating/stripping process over 4000 cycles at a high current density of 6 mA cm^-2.This finding provides an avenue to facilitate fast ion diffusion kinetics of Mg metal anodes in conventional electrolytes.Ruijing Lv Xuze G uan Jiahua Zhang Yongyao Xia Jiayan Luo 2020National Science Review2020,7,2:2
18Numerical Study of Square Border Ultrasonic Transducer Element Arrays for Breast Imaging in Ultrasound Computed Tomography with Waveform Inversion Method显示文摘Ultrasound computed tomography (USCT) is a promising approach for early breast cancer screening. Existing studies that estimate breast images using Waveform inversion (WI) methods utilize a Circular ultrasonic transducer element array (CUTA) to collect the measurement data. However, very accurate transducer element positioning and directivity are required for signal calibration in the hardware system of these studies, thereby causing difficulties in hardware manufacturing. The purpose of this study is to estimate high-resolution USCT images using a WI method with a Square border ultrasonic transducer element array (SUTA), which reduces the difficulty of hardware manufacturing and creates accurate correspondence between the continuous and discrete forms of the transducer element positions. Therefore, in this study, an SUTA is adopted to collect the measurement data of breast imaging using the WI method. A penalized least-squares optimization problem is constructed to obtain the numerical solution of a sound speed distribution. Computer simulations are conducted to compare images reconstructed from the measurement data that are collected using an SUTA and a CUTA. The performance is evaluated using a numerical breast phantom. Results suggest that the biases of the images reconstructed are less than 1% with the evenly distributed SUTA and 1% with the CUTA, under a noise condition.LI Ruijing CHEN Houjin PENG Yahui LI Jupeng 2019Chinese Journal of Electronics2019,28,5:2
19Demand and distributional effects of water pricing policies 显示文摘RUIJS A ZIMMIRMANN A BERG M 2008Ecological Economics2008,66,2:1
20Isolation and characterization of abscisic acid-deficient Arabidopsis mutants at two new loci显示文摘Leon-Kloosterziel K M Gil M A Ruijs G J 1996Plant J1996,10,:1
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