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| 1 | Protective effects of kidney-tonifying Chinese herbal preparation on substantia nigra neurons in a mouse model of Parkinson's disease显示文摘The Chinese herbs Herba Epimedii, Fructus Ligustri Lucidi and Rhizoma Polygonati were injected into Parkinson's disease mice established via intraperitoneal injection of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine hydrochloride. The selective monoamine oxidase B inhibitor selegiline was used as a positive control drug. After successive administration for 4 weeks, Herba Epimedii could downregulate the expression of caspase-3 and increase the brain-derived neurotrophic factor level, as well as increase tyrosine hydroxylase activity in the substantia nigra of Parkinson's disease mouse models. Rhizoma Polygonati could downregulate the expression of caspase-3 and FasL, and increase neural growth factor and brain-derived neurotrophic factor levels. Fructus Ligustri Lucidi could downregulate caspase-3 expression. Rhizoma Polygonati and Fructus Ligustri Lucidi did not produce obvious effects on tyrosine hydroxylase activity. Herba Epimedii and Fructus Ligustri Lucidi yielded similar effects on apoptosis-promoting factors to those elicited by selegiline. Herba Epimedii and Rhizoma Polygonati significantly increased the levels of neurotrophic factors compared with selegiline. Herba Epimedii significantly increased tyrosine hydroxylase activity compared with selegiline. It is indicated that the kidney-tonifying Chinese herbal preparation can downregulate the expression of apoptosis-promoting factors, increase neurotrophic factors levels in the substantia nigra and striatum, as well as increase tyrosine hydroxylase activity in the substantia nigra of Parkinson's disease mouse models, thereby exerting a stronger or similar neuroprotective effects compared with selegiline. | Jing Cai Yun Tian Ruhui Lin Xuzheng Chen Zhizhen Liu Jindong Xie | 2012 | Neural Regeneration Research2012，7，6： | 5 |
| 2 | Collaborative Control of Novel Uninterrupted Propulsion System for All-Climate Electric Vehicles显示文摘Over the past decade,the electric vehicle industry of China has developed rapidly,reaching one of the highest technological levels in the world.Nevertheless,most electric buses currently serve urban areas,being unsuitable for all-climate operations.In response to the objective of massively adopting electric vehicles for transportation during all the events of the 2022 Beijing Winter Olympics,a dual-motor coaxial propulsion system for all-climate electric vehicles is proposed.The system aims to meet operating requirements such as high speed and adaptability to mountainous roads under severely cold environments.The system provides three operating modes,whose characteristics are analyzed under different conditions.In addition,dual-motor collaborative control strategy with collaborative gearshift and collaborative power distribution is proposed to eliminate power interruption during gearshift process and achieve intelligent power distribution,thus improving the gearshift quality and reducing energy consumption.Finally,gear position calibration for all-climate operation and proper gearshift is introduced.Experimental results demonstrate the advantages of the proposed dual-motor coaxial propulsion system regard-ing gearshift compared with the conventional single-motor automatic transmission. | Cheng Lin Xiao Yu Mingjie Zhao Jiang Yi Ruhui Zhang | 2022 | Automotive Innovation2022，5，1： | 4 |
| 3 | Electroluminescence efficiency in bilayer organic light-emitting devices with LiF/Al cathode显示文摘An analytical model to calculate electroluminescence (EL) efficiency of bilayer organic light-emitting devices, considering the influence of introducing LiF insulating buffer layer at metal/organic interface on the barrier height for electron injection, was presented. The relations of EL efficiency versus the applied voltage and injection barrier or internal interfacial barrier or the thickness of organic layer were discussed. The results indicate that: (1) when δ e/δ h < 2, metal/organic (M/O) interface is ohmic contact; when δ e/δ h > 2, M/O becomes contact limited; and when δ e/δ h = 2 (Φ h ~ 0.2 eV, Φ e ~ 0.3 eV), there is a transition from ohmic contact to contact limited; (2) η EL decreases with the increase of δ′e / δ′h; however, when δ′e / δ′h > 2.5 (H ′h~ 0.2 eV, H ′e~ 0.4 eV), the changes of η EL are very small, which shows that η EL is dominated by the carrier’s injection; (3) when increasing Lh/L, η R has a descending trend at low voltage and a rising one at higher voltage. For a given Lh/L, η EL first increases and then decreases with the increasing applied voltage, and as Lh/L further increases, the variation tendency of η EL is more obvious. These conclusions are in agreement with the reported theoretic and experimental results. | LI HongJian ZHU RuHui YAN LingLing ZHANG HaiYan | 2007 | Science China(Physics,Mechanics & Astronomy)2007，50，1： | 4 |
| 4 | Synthesis of polyurea from 1,6-hexanediamine with CO_2 through a two-step polymerization显示文摘Activation and transformation of CO_2 is one of the important issues in the field of green and sustainable chemistry. Herein, CO_2 as a carbonoxygen resource was converted to CO_2-polyurea with 1,6-hexanediamine through a two-step polymerization. The reaction parameters such as temperature, pressure and reaction time were examined; and several kinds of catalysts were screened in the absence and presence of NMP solvent. The formed oligomer and the final polyurea were characterized by FT-IR, VT-DRIFTS, NMR, XRD, AFM and their thermal properties were examined by TGA and DSC. It was confirmed that the final polyurea has a high thermal stability; the melting temperature is 269℃ and the decomposition temperature is above 300℃. It is a brittle polymer with a tensile strength of 18.35 MPa at break length of 1.64%. The polyurea has a stronger solvent resistance due to the ordered hydrogen bond in structure. The average molecular weight should be enhanced in the postpolymerization as the appearance, hydrogen bond intensity, crystallinity, melting point and the thermal stability changed largely compared to the oligomer. The present work provides a new kind of polyurea, it is expected to have a wide application in the field of polymer materials. | Shan Jiang Ruhui Shi Haiyang Cheng Chao Zhang Fengyu Zhao | 2017 | Green Energy & Environment2017，2，4： | 2 |
| 5 | Gua Lou Gui Zhi decoction suppresses LPS-induced activation of the TLR4/NF-κBpathway in BV-2 murine microglial cells显示文摘 | Haixia Hu Zuanfang Li Xiaoqin Zhu Ruhui Lin Jiumao Lin Jun Peng Jing Tao Lidian Chen | 2013 | International Journal of Molecular Medicine2013，，6： | 2 |
| 6 | Differentiation of Induced Pluripotent Stem Cells into Male Germ Cells In Vitro through Embryoid Body Formation and Retinoic Acid or Testosterone Induction显示文摘 | Peng Li Hongliang Hu Shi Yang Ruhui Tian Zhenzhen Zhang Wei Zhang Meng Ma Yong Zhu Xizhi Guo Yiran Huang Zuping He Zheng Li Xuan Jin | 2012 | BioMed Research International2012，，： | 2 |
| 7 | MTCrossBit: A dynamic binary translation system based on multithreaded optimization显示文摘Dynamic optimization has been proposed to overcome many limitations caused by static optimization and is widely applied in dynamic binary translation (DBT) to effectively enhance system performance.However,almost all the existing dynamic optimization techniques or methods employed in DBT systems for a single-threaded executive environment considerably increase the complexity of the hardware or the striking runtime overhead.We propose a multithreaded DBT framework with no associated hardware called the MTCrossBit,where a helper thread for building a hot trace is employed to significantly reduce the overhead.In addition,the main thread and helper thread are each assigned to different cores to use the multi-core resources efficiently to attain better performance,two novel methods yet to be implemented in the MTCrossBit are presented: the dual-special-parallel translation caches and the new lock-free threads communication mechanism—assembly language communication (ASLC).We then apply quantitative analysis to prove that MTCrossBit can speed up the original CrossBit.Simultaneously,we present results from the implementation of the MTCrossBit on the uniprocessor machines with multi-cores utilizing the benchmark-SPECint 2000,and illustrate that we achieved some success with the above concurrent architecture. | GUAN HaiBing MA RuHui YANG HongBo YANG YinDong LIU Liang CHEN Ying | 2011 | Science China(Information Sciences)2011，54，10： | 2 |
| 8 | Suppression of NF-κB pathway by crocetin contributes to attenuation of lipopolysaccharide-induced acute lung injury in mice显示文摘 | Ruhui Yang Lina Yang Xiangchun Shen Wenyuan Cheng Bohua Zhao Kazi Hamid Ali Zhiyu Qian Hui Ji | 2011 | European Journal of Pharmacology2011，，2： | 1 |
| 9 | Inhibitory effect on protein kinase Cθ by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes显示文摘 | Lina Yang Zhiyu Qian Hui Ji Ruhui Yang Yuhuan Wang Liang Xi Liang Sheng Bohua Zhao Xiaoming Zhang | 2010 | European Journal of Pharmacology2010，，1： | 1 |
| 10 | Subdivision Surface-Based Isogeometric Boundary Element Method for Steady Heat Conduction Problems with Variable Coefficient显示文摘The present work couples isogeometric analysis(IGA)and boundary element methods(BEM)for three dimensional steady heat conduction problems with variable coefficients.The Computer-Aided Design(CAD)geometries are built by subdivision surfaces,and meantime the basis functions of subdivision surfaces are employed to discretize the boundary integral equations for heat conduction analysis.Moreover,the radial integration method is adopted to transform the additional domain integrals caused by variable coefficients to the boundary integrals.Several numerical examples are provided to demonstrate the correctness and advantages of the proposed algorithm in the integration of CAD and numerical analysis. | Xiuyun Chen Xiaomeng Yin Kunpeng Li Ruhui Cheng Yanming Xu Wei Zhang | 2021 | Computer Modeling in Engineering & Sciences2021，，10： | 1 |
| 11 | Influence of hyper- homocysteinemia on left ventricular diastolic function in Chi- nese patients with hypertension显示文摘 | RUHUI L JINFA J JIAHONG X | 2014 | Herz2014，5，： | 1 |
| 12 | Cache isolation for vir- tualization of mixed general-purpose and real-time systems 显示文摘 | Ma Ruhui Ye Wei Liang Alei | 2013 | Journal of Systems Architecture2013，59，10： | 1 |
| 13 | Jiangu Guben cap- sule containing serum into the experimental study on the effect of bone cells in rats 显示文摘 | Shen Xiangchun Yang Ruhui Peng Jiao | 2010 | Chinese Journal of traditional Chinese Medi- cine2010，2，： | 1 |
| 14 | Polymorphisms in inter eu kin 17A gene and coal workers' pneumoconiosis risk in a clinese population显示文摘 | Ruhui Han Xiaoming Ji Baiqun Wu | 2015 | BMC Pulmonary Medicine2015，15，： | 1 |
| 15 | GITR promoter poly morphism contributes to risk of coal worker's pneumoconiosis: A case-control study from China 显示文摘 | Baiqun Wu Xiaoming Ji Ruhui Han | 2014 | Immunology Letters2014，162，： | 1 |
| 16 | Credit Scheduling for High Performance Network Virtualization显示文摘 | Hibo Chang Jian Li Ruhui Ma Adjustable | 2012 | IEEE2012，，： | 1 |
| 17 | Network anomaly detection for wavelet neural network based on QPSO 显示文摘 | Liu Yuan Ma Ruhui Lin Xing | 2011 | Journal of Liaoning Technical University:Natural Science2011，28，2： | 1 |
| 18 | Design of a method for encrypted P2P traffic identification using k-means algorithm显示文摘 | DU Ye ZHANG Ruhui | 2013 | Telecommunication Systems2013，53，1： | 1 |
| 19 | Machine Learning Enhanced Boundary Element Method:Prediction of Gaussian Quadrature Points显示文摘This paper applies a machine learning technique to find a general and efficient numerical integration scheme for boundary element methods.A model based on the neural network multi-classification algorithmis constructed to find the minimum number of Gaussian quadrature points satisfying the given accuracy.The constructed model is trained by using a large amount of data calculated in the traditional boundary element method and the optimal network architecture is selected.The two-dimensional potential problem of a circular structure is tested and analyzed based on the determined model,and the accuracy of the model is about 90%.Finally,by incorporating the predicted Gaussian quadrature points into the boundary element analysis,we find that the numerical solution and the analytical solution are in good agreement,which verifies the robustness of the proposed method. | Ruhui Cheng Xiaomeng Yin Leilei Chen | 2022 | Computer Modeling in Engineering & Sciences2022，，4： | 1 |
| 20 | Immunohistochemistry analysis of protein p27kip1 in oral squamous cell carcinoma显示文摘 | Liu Wenshu Zhang Ruhui GE Xi yuan | | 0，，： | 1 |
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