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1TD-AltBOC:A new COMPASS B2 modulation显示文摘AltBOC(15,10) is the baseline of COMPASS B2 signal modulation.It is a BOC-like signal having different PN codes in the lower and the upper main split lobes,which allow one signal service per lobe.The two lobes can be received and processed separately like two BPSK(10) signals,or coherently processed to achieve better performance.Interoperability among COMPASS B2,Galileo E5 and GPS L5 is also achievable using AltBOC modulation.However,Galileo's 4-code AltBOC has drawbacks such as low efficiency and great receiver complexity.This paper presents a new modulation type named TD-AltBOC (Time Division AltBOC).The signal generation scheme and receiving method are presented,and are compared with AltBOC in the areas of power spectrum,ranging accuracy,anti-multipath performance,anti-interference performance,processing flexibility and complexity.Analysis results show TD-AltBOC has similar spectrum characteristics,interoperability,flexibility and anti-interference performance with AltBOC.When the frontend bandwidth is more than 50 MHz,TD-AltBOC can achieve better ranging accuracy and anti-multipath performance.It also has such advantages as high efficiency and low receiver complexity.TD-AltBOC could be a good solution to COMPASS B2 navigation signal.TANG ZuPing ZHOU HongWei WEI JiaoLong YAN Tao LIU YuQi RAN YiHang ZHOU YanLing 2011Science China(Physics,Mechanics & Astronomy)2011,54,6:20
2Generation of male germ cells from induced pluripotent stem cells (iPS cells): an in vitro and in vivo study显示文摘最近的研究报导了从老鼠和人的房间能区分进初发的细菌房间的那导致的 pluripotent 茎(iPS ) 。然而, iPS 房间是否能够生产男细菌房间,不被知道。这研究的目的进 spermatogonial 干细胞和迟了阶段的男细菌房间的老鼠 iPS 房间是调查区别潜在的。我们使用了在 vitro 区别并且在 vivo 移植联合的一条途径。胚胎植物或动物身体(EB ) 用白血球过多症禁止者因素(LIF ) 从 iPS 房间被获得免费媒介。量的 PCR 表明在 Oct4 表示的减少和 Stra8 的增加和在 EB 的 Vasa mRNA 源于 iPS 房间。iPS 导出房间的 EB 被区分进 spermatogonial 干细胞(SSC ) ,,的酸由他们 VASA,以及 CDH1 和 GFRα 的表示证实了的 retinoic 导致; 1,它是 SSC 的标记。而且,从 iPS 房间导出的这些细菌房间被移植进与 busulfan 被预先对待的老鼠的接受者睾丸。尤其是, iPS 导出房间的 SSC 能区分进从 spermatogonia 到圆 spermatids,由 VASA 和 SCP3 表示出现的男细菌房间。这研究证明 iPS 房间有潜力区分进迟了阶段的男细菌房间。从 iPS 房间的男细菌房间的推导在男不孕的处理有潜在的应用程序并且为揭开提供一个模型位于男细菌房间开发下面的分子的机制。Yong Zhu Hong-Liang Hu Peng Li Shi Yang Wei Zhang Hui Ding Ru-Hui Tian Ye Ning Ling-Ling Zhang Xi-Zhi Guo Zhan-Ping Shi Zheng Li Zuping He 2012Asian Journal of Andrology2012,14,4:13
3Trends in the major causes of death in China, 1982-2010显示文摘Since the introduction of a series of reform and open policies in its economic system in 1976,China has been in a boom period of social and economic fields.Rapid development in economy and the consequent improvement in living conditions,nutrition,and health care help to decrease infant mortality and deaths from infectious diseases,and notably effected the patterns of mortality.For example,respiratory diseases,acute infectious diseases,and tuberculosis were the leading causes of death in 1957,while diseases of heart,cerebrovascular disease,and malignant neoplasm were the fifth,sixth,and seventh leading causes of death.1 Up to 1975,cerebrovascular diseases,diseases of heart,and malignant neoplasm were the top three death causes,followed by respiratory diseases,digestive diseases,and pulmonary tuberculosis.1 A prospective cohort study involving a representative sample of the adult Chinese population was conducted in 2005,which revealed that the five leading causes of death were malignant neoplasm,diseases of heart,cerebrovascular disease,accidents,and infectious diseases among men and diseases of heart,cerebrovascular disease,malignant neoplasm,pneumonia and influenza,and infectious diseases among women.Lian Zuping Xie Youke Lu Yunxin Huang Dingping Shi Huanzhong 2014Chinese Medical Journal2014,,4:13
4The effective pressure law for permeability of clay-rich sandstones显示文摘To study the relative sensitivity of permeability to pore pressure Pp and confining pressure Pc for clay-rich rocks,permeability measurements were performed on samples of four clay-rich sandstones.A new method(hereafter denoted the 'slide method') was developed and used for analyzing the permeability data obtained.The effective pressure coefficients for permeability nk were calculated.The values of nk were found to be greater than 1.0 and insensitive to changes in pressure.These results confirmed observations previously made on clay-rich rocks.Also,the coefficients nk obtained had different characteristics for different samples because of differences in the types of clay they contained.The effective pressure law(σeff=Pc-nkPp) determined using the slide method gave better results about k(σeff) than classic Terzaghi's law(σeff=Pc-Pp).Zhao Jinzhou Xiao Wenlian Li Min Xiang Zuping Li Lijun Wang Jun 2011Petroleum Science2011,8,2:9
5Exosomes:key players in cancer and potential therapeutic strategy显示文摘Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in intercellular communication.The components of exosomes,including proteins,DNA,mRNA,microRNA,long noncoding RNA,circular RNA,etc.,which play a crucial role in regulating tumor growth,metastasis,and angiogenesis in the process of cancer development,and can be used as a prognostic marker and/or grading basis for tumor patients.Hereby,we mainly summarized as followed:the role of exosome contents in cancer,focusing on proteins and noncoding RNA;the interaction between exosomes and tumor microenvironment;the mechanisms that epithelial-mesenchymal transition,invasion and migration of tumor affected by exosomes;and tumor suppression strategies based on exosomes.Finally,the application potential of exosomes in clinical tumor diagnosis and therapy is prospected,which providing theoretical supports for using exosomes to serve precise tumor treatment in the clinic.Jie Dai Yangzhou Su Suye Zhong Li Cong Bang Liu Junjun Yang Yongguang Tao Zuping He Chao Chen Yiqun Jiang 2020Signal Transduction and Targeted Therapy2020,5,1:8
6Derivation of male germ cells from induced pluripotent stem (iPS) cells: a novel and crucial source for generating male gametes显示文摘Zuping He 2012Asian Journal of Andrology2012,14,4:3
7NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients显示文摘Ru-Hui Tian Shi Yang Zi-Jue Zhu Jun-Long Wang Yun Liu Chencheng Yao Meng Ma Ying Guo Qingqing Yuan Yanan Hai Yi-Ran Huang Zuping He Zheng Li 2015Asian Journal of Andrology2015,17,6:2
8Advances in studies on hepatic stem cells显示文摘The question whether hepatic stem cells exist or not has been debated for several decades. Current researches confirm that there are hepatic stem cells in the liver. Oval cells, putative bipotential hepatic stem cells, are probably located within canals of Hering, portal tracts or branches of biliary trees. Bone marrow is a potential source of oval cells, indicating that there exists a close relationship between liver and hematopoiesis in adulthood. Hepatic stem cells are able to proliferate in vitro and can be induced to differentiate into hepatocytes. This will provide a promising approach of cell transplantation, tissue engineering and gene therapy for liver diseases. In this review, the evidence of their presence, origin, identification, proliferation in vitro, differentiation by induction, application prospects of hepatic stem cells and future directions for the field are discussed.HE Zuping, TANG Yuefeng, LIU Yabing and FENG Meifu(State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China) 2003Progress in Natural Science:Materials International2003,13,3:2
9Differentiation of Induced Pluripotent Stem Cells into Male Germ Cells In Vitro through Embryoid Body Formation and Retinoic Acid or Testosterone Induction显示文摘Peng Li Hongliang Hu Shi Yang Ruhui Tian Zhenzhen Zhang Wei Zhang Meng Ma Yong Zhu Xizhi Guo Yiran Huang Zuping He Zheng Li Xuan Jin 2012BioMed Research International2012,,:2
10Plasticity of male germline stem cells and their applications in reproductive and regenerative medicine显示文摘Spermatogonial 干细胞(SSC ) ,也已知的同样男的 germline 干细胞,是小 subpopulation 与自强的潜力打 spermatogonia 在哺乳动物的睾丸维持干细胞水池和区别进 spermatids。自从他们能仅仅在生精的小管以内产生精子, SSC 以前被认为是 unipotent 干细胞。然而,因为众多的研究证明了与生长因素有教养的 SSC 能获得 pluripotency 成为胚胎的像茎的细胞,这个概念最近被质问了。在里面 vivo 并且在 vitro,从同伴和我们的研究清楚地表明了那 SSC 直接装 transdifferentiate 进词法,另外的系的 phenotypic,和功能的房间。到另外的纸巾的房间的直接变换为再生药有重要意义。从精子缺乏病人的 SSC 能被导致与授精和发展潜力区分进 spermatids。因此, SSC 能由于他们的唯一、大的潜力在繁殖、再生的药有重要应用。在这评论,我们探讨 SSC 的重要粘性,与他们的自强,区别, dedifferentiation, transdifferentiation,和翻译的药研究的焦点。Zheng Chen Zheng Li Zuping He 2015Asian Journal of Andrology2015,17,3:2
11A ROBUST PHASE-ONLY DIRECT DATA DOMAIN ALGORITHM BASED ON GENERALIZED RAYLEIGH QUOTIENT OPTIMIZATION USING HYBRID GENETIC ALGORITHM显示文摘A robust phase-only Direct Data Domain Least Squares (D3LS) algorithm based on gen- eralized Rayleigh quotient optimization using hybrid Genetic Algorithm (GA) is presented in this letter. The optimization efficiency and computational speed are improved via the hybrid GA com- posed of standard GA and Nelder-Mead simplex algorithms. First, the objective function, with a form of generalized Rayleigh quotient, is derived via the standard D3LS algorithm. It is then taken as a fitness function and the unknown phases of all adaptive weights are taken as decision variables. Then, the nonlinear optimization is performed via the hybrid GA to obtain the optimized solution of phase-only adaptive weights. As a phase-only adaptive algorithm, the proposed algorithm is sim- pler than conventional algorithms when it comes to hardware implementation. Moreover, it proc- esses only a single snapshot data as opposed to forming sample covariance matrix and operating matrix inversion. Simulation results show that the proposed algorithm has a good signal recovery and interferences nulling performance, which are superior to that of the phase-only D3LS algorithm based on standard GA.Shao Wei Qian Zuping Yuan Feng 2007Journal of Electronics(China)2007,24,4:2
12The interwell interference effect on numerical well test curve of oil-water phase显示文摘Zhang Liehui Xiang Zuping Li Yun Li Xiaoping Liu Qiguo 2006Journal of Hydrodynamics (Series A)2006,21,6:1
13Cyclic di-adenosine monophosphate regulates the osteogenic and adipogenic differentiation of hPDLSCs via MAPK and NF-κB signaling显示文摘Cyclic di-adenosine monophosphate(c-di-AMP)is a bacterial second messenger that can be recognized by infected host cells and activate the immunoinflammatory response.The purpose of this study is to demonstrate the effect of c-di-AMP on the differentiation of human periodontal ligament stem cells(hPDLSCs)and its underlying mechanisms.In the present study,we find that the gingival crevicular fluid(GCF)of patients with chronic periodontitis has a higher expression level of c-di-AMP than that of healthy people.In vitro,c-di-AMP influences the differentiation of hPDLSCs by upregulating Toll-like receptors(TLRs);specifically,it inhibits osteogenic differentiation by activating NF-κB and ERK/MAPK and promotes adipogenic differentiation through the NF-κB and p38/MAPK signaling pathways.Inhibitors of TLRs or activated pathways reduce the changes induced by c-di-AMP.Our results establish the potential correlation among bacterial c-di-AMP,periodontal tissue homeostasis and chronic periodontitis pathogenesis.Sirui Chen Zuping Wu Yuying He Li Zhu Jiahe Wang Hengyi Lin Jing Xie Chenchen Zhou Shujuan Zou 2023Acta Biochimica et Biophysica Sinica2023,55,3:1
14Advancements in Immune Tolerance显示文摘Ping-Ying Pan Junko Ozao Zuping Zhou 0,,02:1
15Effects of different hematocrit levels on glucose measurements with handheld meters for point of care testing显示文摘Zuping Tang Judith H Lee Richard F Louie 2000Arch Pathol Lab Med2000,124,:1
16POTEH hypomethylation, a new epigenetic biomarker for glioma prognosis 显示文摘XIAOPING L HAILIN T ZUPING Z 2011Brain Res2011,1391,:1
17A Semi-supervised Method for Drug-target Interaction Prediction with Consistency in Nnetworks显示文摘Chen Hailin Zhang Zuping 2013Plo S ONE2013,8,5:1
18POTEH hypomethylation, a new epigenetic biomarker for glioma prognosis 显示文摘Xiaoping L Hailin T Zuping Z 2011Brain Res2011,1391,:1
19GROWTH OF DIAMOND-LIKE FILMS BY DC PLASMA CHEMICAL VAPOR DEPOSITION显示文摘Diamond-like films have been deposited by dc plasma chemical vapor deposition(CVD).During deposition,the characteristics of the plasma have been measured by means of the Langmuir single probe.The structure of the deposits has been studied by X-ray diffraction,Raman spectroscopy and Fourier transform infrared spectroscopy.ZHAN Rujuan GAO Kelin ZOU Zuping WANG Yanxia LIU Jiezhou XIANG Zhilin LIU Hongtu WU Zhiqiang YE Jian ZHOU Guien WANG Changsui 1990Chinese Physics Letters1990,7,10:1
20Advancements in Immune Tolerance显示文摘Pan Ping-Ying Ozao Junko Zhou Zuping 2008Adv Drug Deliv Rev2008,60,2:1
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