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| 1 | Performance of the Montreal classification for inflammatory bowel diseases显示文摘AIM:To validate the Montreal classification system for Crohn's disease(CD) and ulcerative colitis(UC) within the Netherlands.METHODS:A selection of 20 de-identified medical records with an appropriate representation of the inflammatory bowel disease(IBD) sub phenotypes were scored by 30 observers with different professions(gastroenterologist specialist in IBD,gastroenterologist in training and IBD-nurses) and experience level with IBD patient care.Patients were classified according to the Montreal classification.In addition,participants were asked to score extra-intestinal manifestations(EIM) and disease severity in CD based on their clinical judgment.The inter-observer agreement was calculated by percentages of correct answers(answers identical to the 'expert evaluation') and Fleiss-kappa(k).Kappa cutoffs:< 0.4-poor; 0.41-0.6-moderate; 0.61-0.8-good; > 0.8 excellent.RESULTS:The inter-observer agreement was excellent for diagnosis(k = 0.96),perianal disease(k = 0.92) and disease location in CD(k = 0.82) and good for age of onset(k = 0.67),upper gastrointestinal disease(k = 0.62),disease behaviour in CD(k = 0.79) and disease extent in UC(k = 0.65).Disease severity in UC was scored poor(k = 0.23).The additional items resulted in a good inter-observer agreement for EIM(k = 0.68) and a moderate agreement for disease severity in CD(k = 0.44).Percentages of correct answers over all Montreal items give a good reflection of the inter-observer agreement(> 80%),except for disease severity(48%-74%).IBD-nurses were significantly worse in scoring upper gastrointestinal disease in CD compared to gastroenterologists(P = 0.008) and gastroenterologists in training(P = 0.040).Observers with less than 10 years of experience were significantly better at scoring UC severity than observers with 10-20 years(P = 0.003) and more than 20 years(P = 0.003) of experience with IBD patient care.Observers with 10-20 years of experience with IBD patient care were significantly better at scoring upper gastrointestinal disease in CD than observers with less than 10 years(P = 0.007) and more than 20 years(P = 0.007) of experience with IBD patient care.CONCLUSION:We found a good to excellent interobserver agreement for all Montreal items except for disease severity in UC(poor). | Lieke M Spekhorst Marijn C Visschedijk Rudi Alberts Eleonora A Festen Egbert-Jan van der Wouden Gerard Dijkstra Rinse K Weersma | 2014 | World Journal of Gastroenterology2014，20，41： | 4 |
| 2 | Effect of NaCl-induced osmotic stress on intracellular concentrations of glycine betaine and potassium in Escherichia coli,Enterococcus faecalis,and staphylococci显示文摘 | Kunin C M Rudy J | 1991 | J Lab Clin Med1991，118，： | 1 |
| 3 | The origin of oxidative stress in neurodesenerative disease: Mark Anthony Smith 1965 - 2010 显示文摘 | Zhu X W Rudy J Lee C H | 2011 | Free Radical Bio Med2011，51，2： | 1 |
| 4 | A model of the ventricular cardiac action potential :depolarization ,repolarization,and their interaction显示文摘 | LUO C RUDY Y | 1991 | Cite Res1991，68，： | 1 |
| 5 | Diversity of helicobacter pylori vac A and cag A gene and relationship to Vac A and Cag A protein expression, cytotoxin production, and associated diseases 显示文摘 | Rudi J Kolb C Malwald M | 1998 | J Clin Microbiol1998，36，： | 1 |
| 6 | The effect of electromagnetic stirring and mechanical vibration on arc welds 显示文摘 | Brown D C Crossley F A Rudy J F | 1962 | Welding Journal1962，41，6： | 1 |
| 7 | The application of pH-stat leaching tests to assess the pH-dependent release of trace metals from soils, sediments and waste materials显示文摘 | Val~rie C Rudy S | 2008 | Journal of Hazardous Materials2008，158，： | 1 |
| 8 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 9 | The effect of electromagnetic stirring and mechanical vibration on arc welding 显示文摘 | Brown D C Croossley F A Rudy J F et at | 1962 | Welding Journal1962，41，6： | 1 |
| 10 | Toward the understanding of the thermal degradation of commercially available fire-resistant cable显示文摘 | Andre R Rudi C | 2000 | Material Letters2000，46，： | 1 |
| 11 | Bowed injury in gynecologic laparoscopy显示文摘 | IVO B ALAN C RUDI C | 2003 | J Am Assco Gynecol Laparosc2003，10，： | 1 |
| 12 | Resolution, quantification and confirmation of betamethasone and dexamethasone in equine plasma by liquid chromatography/tandem mass spectrometry显示文摘 | Luo Y Uboh C E Soma L R Guan F Rudy J A Tsang D S | 2005 | Rapid Commun Mass Spectrom2005，19，： | 1 |
| 13 | Surface modification of carbon black by oxidation and its influence on the activity of immobilized catalase and iron-phthalocyanines 显示文摘 | Rosario C S Rudy F P Patricia E N | 1996 | Journal of Molecular Catalysis A : Chemical1996，110，2： | 1 |
| 14 | Toward the understanding of the thermal degradation of Commercially Available Fire-resistant Cable显示文摘 | Catherine H Andre R Rudi C et al | 2000 | Material Letters2000，46，： | 1 |
| 15 | Toward the under- standing of the thermal degradation of commercially avail- able fire-resistant cable显示文摘 | Catherine H Andre R Rudi C | 2000 | Material Letters2000，46，： | 1 |
| 16 | Peripheral blood lymphocyte subsets in adolescents: a longitudinal analysis from the REACH project显示文摘 | Rudy B J Wilson C M Durako S | 2002 | Clin Diagn Lab Immunol2002，9，5： | 1 |
| 17 | The effect of dectromagnetic stirring and mechanical vibration on arc welds显示文摘 | Brown D C Crossley F A Rudy J F | 1962 | Welding Journal1962，41，6： | 1 |
| 18 | A dynamic model of the cardiac ventricular action potential: ISimulation of ionic currents and concentration changes显示文摘 | Luo C Rudy Y | 1994 | Circulation Research1994，74，： | 1 |
| 19 | The application of pHstat leaching tests to assess the pH-dependent release ot trace metals irom soils, sediments and waste materials显示文摘 | Val6rie C Rudy S | 2008 | Journal of Hazardous Materials2008，158，1： | 1 |
| 20 | A dynamic model of the cardiac ventricular action potential: IIAfterdepolarization, triggered activity, and potentiation显示文摘 | Luo C Rudy Y | 1994 | Circulation Research1994，74，： | 1 |
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