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1Stability of weak solutions to climate dynamics model with effects of topography and non-constant external force显示文摘In this paper, a climate dynamics model with the effects of topography and a non-constant external force, which consists of the Navier-Stokes equations and a temperature equation arising from the evolution process of the atmosphere, was considered.Under certain assumptions imposed on the initial data and by using some delicate estimates and compactness arguments, we proved the L^1-stability of weak solutions to the atmospheric equations.LIAN RuXu ZENG QingCun JIN JiangBo 2018Science China Earth Sciences2018,61,1:6
2Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332显示文摘Dear Editor,Since December 2019,the pandemic of coronavirus disease 2019(COVID-19)has taken a heavy toll on global health,creating an urgent need to develop effective strategies for prevention and treatment.The etiological agent,known as severe acute respiratory syndrome coronavirus 2(SARSCoV-2),has infected nearly 229.2 million people worldwide with more than 4.7 million deaths as of September 15,2021.Older age and preexisting health conditions are associated with worse clinical prognosis including higher mortality rates(Zhou et al.,2020).The global race to combat this pandemic has led to rapid deployment of numerous effective vaccines against SARS-CoV-2(Tregoning et al.,2021).However,the emergence of viral variants,including the Delta variant(B.1.617.2),compromised vaccine effectiveness with resurgence of SARS-CoV-2 infection among highly vaccinated population(Keehner et al.,2021).Therefore,development of therapeutics against the more conserved viral targets would be essential to contain the spread of COVID-19 and reduce mortality.Yao Zhao Chao Fang Qi Zhang Ruxue Zhang Xiangbo Zhao Yinkai Duan Haofeng Wang Yan Zhu Lu Feng Jinyi Zhao Maolin Shao Xiuna Yang Leike Zhang Chao Peng Kailin Yang Dawei Ma Zihe Rao Haitao Yang 2022Protein & Cell2022,13,9:6
3Selective Electrochemical Reduction of Nitrogen to Ammonia by Adjusting the Three-Phase Interface显示文摘The electrochemical nitrogen reduction reaction(NRR)provides a sustainable and alternative avenue to the Haber-Bosch process for ammonia(NH_(3))synthesis.Despite the great efforts made on catalysts and electrolytes,unfortunately,current NRR suffers from low selectivity due to the overwhelming competition with the hydrogen evolution reaction(HER).Here,we present an adjusted three-phase interface to enhance nitrogen(N_(2))coverage on a catalyst surface and achieve a record-high Faradic efficiency(FE)up to 97%in aqueous solution.The almost entirely suppressed HER process combined with the enhanced NRR activity,benefiting from the efficient three-interface contact line,is responsible for the excellent selectivity toward NH_(3),as evidenced by the theoretical and experimental results.Our strategy also demonstrates the applicability to other catalysts that feature strong H adsorption ability,to boost the FE for NH_(3) synthesis above 90%and to improve the NRR activity by engineering the catalysts.Haiyan Wang Yuzhuo Chen Ruxue Fan Jiadong Chen Zhe Wang Shanjun Mao Yong Wang 2019Research2019,,1:4
4Modeling and numerical simulation of a novel solar-powered absorption air conditioning system driven by a bubble pump with energy storage显示文摘This paper presents a novel solar-powered absorption air conditioning system driven by a bubble pump with energy storage. It solves the problem of unreliable solar energy supply by storing the working fluids and hence, functions 24 h per day. First, the working principles are described and the dynamic models for the primary energy storage components are developed. Then, the system is evaluated based on a numerical simulation. Based on the meteorological data of a typical day in a subtropical area, with the area of a solar collector being set at 19.15 m2, whilst the initial charging mass, mass fraction and temperature of the solution are respectively set at 379.5 kg, 54.16% and 34.5 ℃, it is found that the respective coefficients of performance (COP) of the air conditioning system and the en- tire system (including the solar panel) are 0.7771 and 0.4372. In particular, the energy storage density of the system is 206.69 MJ/m3 which is much greater than those of chilled water or hot water storage systems under comparable conditions. This makes the new system much more compact and efficient. Finally, an automatic control strategy is given to achieve the highest COP when solar energy fluctuates.QIU Jia LIANG Jian CHEN GuangMing DU RuXu 2009Chinese Science Bulletin2009,54,3:4
5Clinical classification and gene mutation of Chinese probands with Charcot-Marie-Tooth disease Analysis of 57 cases显示文摘Charcot-Marie-Tooth(CMT) disease is the most common inherited peripheral neuropathic disorder.CMT is clinically and genetically heterogeneous.To date,27 genes associated with the disease have been cloned.The present study carried out clinical classification according to clinical,electrophysiological and pathological features,conducted inheritance classification according to inheritance patterns,and performed mutation analysis of 13 CMT disease genes(PMP22,CX32,HSPB1,MNF2,MPZ,HSPB8,GDAP1,NFL,EGR2,SIMPLE,RAB7,LMNA,MTMR2) in 57 Chinese probands with CMT.Five cases of AD-CMT1 and 13 cases of sporadic CMT1 were diagnosed as CMT1A;five cases of X-CMT1,one case of X-CMT2 and one case of sporadic CMT1 were diagnosed as CMTX1;four cases of AD-CMT2 were diagnosed as CMT2F;one case of AD-CMT2 and one case of sporadic CMT2 were diagnosed as CMT2A2;one case of AD-CMT2 was diagnosed as CMT2L;one case of AD-CMT2 was diagnosed as CMT2J;one case of AR-CMT1 was diagnosed as CMT4A.Among the 57 CMT probands,seven genotypes were determined among 34 patients,with a detection rate of 59.6%.The results indicated that the clinical classification and inheritance classification are indispensable for selecting potential disease genes for mutation detection,and for efficient molecular diagnosis.Ruxu Zhang Xiaobo Li Xiaohong Zi Shunxiang Huang Fufeng Zhang Kun Xia Qian Pan Beisha Tang 2011Neural Regeneration Research2011,6,9:4
6Central Pattern Generator(CPG)Control of a Biomimetic Robot Fish for Multimodal Swimming显示文摘This paper introduces the design and control of a biomimetic robot fish for multimodal swimming.The biomimetic design consists of three parts:the rigid head,the wire-driven body and the compliant tail.The control is an improved Central Pattern Generator(CPG)with the high-level control command:(M,co,B,R),where M is the amplitude,co is the angular velocity,B is the offtet and R is the time ratio between two phases forming one flapping cycle.This method differs from previous research in two aspects:(1)The CPG control is firstly implemented on the wire-driven robot fish.(2)The improved CPG model synthesizes symmetrical flapping in cruising and asymmetrical flapping in turning for the robot fish.The asymmetrical flapping refers to the asymmetry of the offset and the time ratio.This combination of the design and the control has several advantages over the existing multimodal swimming robot fishes.First,it uses just one driving motor for undulatory oscillation while the others need to use two or more motors.Second,with just one motor,the CPG control can be easily implemented.Third,the use of the time ratio,R,makes the robot fish turn more naturally and effectively.Experimental results show the robot fish achieved the maximum speed of 1.37 Body Length/Second(BL.s-1)and the largest turning rate of 4577s.Additionally,in many swimming conditions,its Strouhal Number falls in the range from 0.2 to 0.4,which implies the robot fish is efficient.Fengran Xie Yong Zhong Ruxu Du Zheng Li 2019Journal of Bionic Engineering2019,16,2:4
7Numerical simulation of the effect of void fraction and inlet velocity on two-phase turbulence in bubble-liquid flows显示文摘有水泡是否提高或减少液体骚乱的矛盾的意见。在这篇论文,空部分的效果和水泡液体上的入口速度,在一条二维的隧道的多重水泡液体喷气的二阶段的骚乱被使用二阶段的秒顺序时刻骚乱模型学习。结果证实在实验观察并且在参考书报导在低空部分和低入口速度,水泡提高液体骚乱的现象,而在高空的部分和高入口速度水泡减少液体骚乱。Lixing Zhou Rongxian Li Ruxu Du 2006Acta Mechanica Sinica2006,22,5:3
8Intermediate Charcot-Marie-Tooth disease显示文摘Charcot-Marie-Tooth(CMT) disease is a common neurogenetic disorder and its heterogeneity is a challenge for genetic diagnostics. The genetic diagnostic procedures for a CMT patient can be explored according to the electrophysiological criteria: very slow motor nerve conduction velocity(MNCV)(<15 m/s), slow MNCV(15–25 m/s), intermediate MNCV(25–45 m/s), and normal MNCV(>45 m/s). Based on the inheritance pattern, intermediate CMT can be divided into dominant(DI-CMT) and recessive types(RI-CMT). GJB1 is currently considered to be associated with X-linked DI-CMT, and MPZ, INF2, DNM2, YARS, GNB4, NEFL, and MFN2 are associated with autosomal DI-CMT. Moreover, GDAP1, KARS, and PLEKHG5 are associated with RI-CMT. Identification of these genes is not only important for patients and families but also provides new information about pathogenesis. It is hoped that this review will lead to a better understanding of intermediate CMT and provide a detailed diagnostic procedure for intermediate CMT.Lei Liu Ruxu Zhang 2014Neuroscience Bulletin2014,30,6:3
9Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model显示文摘Dear Editor,Respiratory syncytial virus(RSV)is the leading cause of serious lower respiratory tract disease in children under 5 years of age worldwide,causing an estimated 3.2 million hospitalizations and 120,000 deaths in children globally per year.Furthermore,nearly all children can be infected with RSV by 2 years of age,and individuals can be repeatedly re-infected with RSV throughout life,which poses great threats to infants,the elderly.Ruxue Zhang Yumin Zhang Wei Zheng Weijuan Shang Yan Wu Ning Li Jun Xiong Hualiang Jiang Jingshan Shen Gengfu Xiao Yuanchao Xie Leike Zhang 2022Signal Transduction and Targeted Therapy2022,7,5:2
10Bioinspired Closed-loop CPG-based Control of a Robot Fish for Obstacle Avoidance and Direction Tracking显示文摘This paper presents a study on bioinspired closed-loop Central Pattern Generator(CPG)based control of a robot fish for obstacle avoidance and direction tracking.The biomimetic robot fish is made of a rigid head with a pair of pectoral fins,a wire-driven active body covered with soft skin,and a compliant tail.The CPG model consists of four input parameters:the flapping amplitude,the flapping angular velocity,the flapping offset,and the time ratio between the beat phase and the restore phase in flapping.The robot fish is equipped with three infrared sensors mounted on the left,front and right of the robot fish,as well as an inertial measurement unit,from which the surrounding obstacles and moving direction can be sensed.Based on these sensor signals,the closed-loop CPG-based control can drive the robot fish to avoid obstacles and to track designated directions.Four sets of experiments are presented,including avoiding a static obstacle,avoiding a moving obstacle,tracking a designated direction and tracking a designated direction with an obstacle in the path.The experiment results indicated that the presented control strategy worked well and the robot fish can accomplish the obstacle avoidance and direction tracking effectively.Jiayong Chen Bo Yin Chengcai Wang Fengran Xie Ruxu Du Yong Zhong 2021Journal of Bionic Engineering2021,18,1:2
11Medical Additive Manufacturing: From a Frontier Technology to the Research and Development of Products显示文摘1.Research and development(R&D)and the challenges of raw materials for medical additive manufacturing Raw materials for medical additive manufacturing have a wide range of commonalities that are also seen in many other fields,making them an important basis in the field of three-dimensional(3D)printing.Problems and challenges related to material types,powder properties,formability,viscoelasticity,and so forth also share common features.For example,many metal materials are used in the field of aviation,while metals,polymers,and inorganic materials are used in the field of biomedicine.The most widely used materials in biomedicine are biocompatible.Various homogeneous and non-homogeneous composites are also available for 3D printing,and impose an additional challenge in additive manufacturing;the use of heterogeneous composites in 3D printing is particularly challenging.Guixing Qiu Wenjiang Ding Wei Tian Ling Qin Yu Zhao Lianmeng Zhang Jian Lu Daijie Chen Guangyi Yuan Chengtie Wu Bingheng Lu Ruxu Du Jimin Chen Mo Elbestawi Zhongwei Gu Dichen Li Wei Sun Yuanjin Zhao Jie He Dadi Jin Bin Liu Kai Zhang Jianmo Li Kam WLeong Dewei Zhao Dingjun Hao Yingfang Ao Xuliang Deng Huilin Yang ShaoKeh Hsu Yingqi Chen Long Li Jianping Fan Guohui Nie Yun Chen Hui Zeng Wei Chen Yuxiao Lai 2020Engineering2020,6,11:1
12Effect of Co content on the structure and electrochemical properties of La 1.5 Mg 0.5 Ni 7? x Co x ( x =0, 1.2, 1.8) hydrogen storage alloys显示文摘Faliang Zhang Yongchun Luo Kai Sun Dahui Wang Ruxu Yan Long Kang Jianhong Chen 2006Journal of Alloys and Compounds2006,,1:1
13Microstructure, thermal and dielectric properties of homogeneous bismaleimide-triazine/barium titanate nanocomposite films显示文摘Xiaoliang Zeng Shuhui Yu Rong Sun Ruxu Du 2011Materials Chemistry and Physics2011,,1:1
14Kinematic analysis of an auto-winding system with the pawl-lever mechanism and its applications in energy harvesting显示文摘Lei M C Xie Longhan Du Ruxu 2010International Journal of Mechanical Sciences2010,52,12:1
15A new sheet metal forming system based on incremental punching,part 2 machine building and experiment results 显示文摘Luo Yuanxin He Kai Du Ruxu 2010The International Journal of Ad- vanced Manufacturing Technology2010,51,5678:1
16Development of a validated HPLC-PAD-APCI/MS method for the identification and determination of iridoid glycosides in Lamiophlomis rotate显示文摘Li Maoxing Zhang Ruxue Li Caixia 2010Anal Methods2010,2,:1
17Rehmannia glutinosa: review of botany,chemistry and pharmacology显示文摘Zhang RuXue Li MaoXing Jia ZhengPing 2008J Ethnopharmacol2008,117,2:1
18Influence of mixed organic cations on the nonlinear optical properties of lead tri-iodide perovskites显示文摘Metal halide perovskite materials have been widely studied recently due to their excellent optoelectronic properties.Among these materials,organic-inorganic hybrid perovskites have attracted much attention because of their relatively soft framework,which makes them more suitable for nonlinear optical(NLO)applications.However,there is rare physical mechanism study on the coexistence of two-photon absorption(TPA)and saturable absorption(SA)in organic-inorganic hybrid perovskite materials.To clarify this issue,the NLO properties of mixed cation perovskite MA1-xFAxPbI3[MA=CH3NH3,FA=CH(NH2)2,x=0,0.2,0.4,0.6,and 0.8]thin films are investigated in this paper.Based on the nonlinear transmittance and femtosecond-transient absorption spectrum measurements,it is found that the MA1-xFAxPbI3 materials exhibit NLO behavior dependent on excitation intensity.The TPA coefficient of MA1-xFAxPbI3 decreases with the increase of formamidinium(FA)content,while the relevant saturable intensity increases.In addition,it is revealed that the linear absorption process from valence band 2 to valance band 1 still exists even under a very low excitation intensity.With the increase of excitation intensity,the light transmittance at 1300 nm decreases first and then increases sharply,which also supports the explanation for the coexistence of TPA and SA.It is expected that our findings will promote the application of perovskite materials in nonlinear optoelectronic devices.XUANYU ZHANG SHUYU XIAO RUXUE LI TINGCHAO HE GUICHUAN XING AND RUI CHEN 2020Photonics Research2020,8,9:1
19显示文摘Wang Dahui Luo Yongchun Yan Ruxu 2007Transactions of Nonferrous Metals Society of China2007,17,:1
20Ameliorating effect and potential mechanism of Rehmannia glutinosa oligosaccharides on the impaired glucose metabolism in chronic stress rats fed with high-fat diet显示文摘Ruxue Zhang Jun Zhou Maoxing Li Haigang Ma Jianguo Qiu Xiaohong Luo Zhengping Jia 2013Phytomedicine2013,,:1
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