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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Antimicrobial activity and phytochemical studies of some lichens from south of Spain显示文摘 | SAENZ M T GARCIA M D ROWE J G | 2006 | Fitoterapia2006，77，： | 1 |
| 3 | Cerebrospinal fluid leak after acoustic neuroma surgery:influence of tumor size and surgical approach on incidence and response to treatment显示文摘 | ROWED D W NEDZELSKI J M | 2001 | J Neurosurgery2001，94，2： | 1 |
| 4 | Progress in cystic fibrosis and the CF Therapeutics Development Network 显示文摘 | Rowe S M Borowitz D S Burns J L ct al | 2012 | Thorax2012，67，10： | 1 |
| 5 | The bfl-1 gene is transcriptionally upregulated by the Epstein-Barr virus LMP1, and its expression promotes the survival of a Burkitt's lymphoma cell line显示文摘 | Dsouza B Rowe M Walls D | 2000 | J Virol2000，74，14： | 1 |
| 6 | 'Symbiotic'application of thermoelectric conversion for fluid preheating/power generation 显示文摘 | Min G Rowe D M | 2001 | Energy Conversion and Management2001，，1： | 1 |
| 7 | Electrical transport properties of SnBi4Te7 and PbBi4Te7 with different deviations from stoichiometry显示文摘 | Kuznetsov V L Kuznetsova L A ROWE D M | | 0，，： | 1 |
| 8 | Applications of nuclear-powered thermoelectric generators in space显示文摘 | Rowe D M | 1991 | Applied Energy1991，40，4： | 1 |
| 9 | 显示文摘 | Zou H Rowe D M Min G | 2001 | Journal of Vacuum Sci- ence and Technology A2001，19，3： | 1 |
| 10 | Extraction and HPLC Analysis of Halofuginone in Chicken Serum显示文摘 | Beier R C Rowe L D Abd El-Aziz Nasr M I | 1994 | J Liquid Chromatogr1994，17，13： | 1 |
| 11 | Value Orientations, Awareness of Consequences, and Participation in a Whale Watching Education Program in Oregon 显示文摘 | Christensen A Rowe S Needham M D | 2007 | Human Dimensions of Wildlife2007，12，4： | 1 |
| 12 | 查看详情显示文摘 | Rowe D M Shukla V S Savvides N | | 0，，5809： | 1 |
| 13 | Facile Synthesis of Carboxylic Linker on Halofuginone:A Method to Derivatize Haptens Containing both Amine and Hydroxy Functionalities显示文摘 | Rowe L D Beier R C Elissalde M H | 1993 | Synthetic Conmunications1993，23，15： | 1 |
| 14 | Is the current BMI obesity classification appropriate for black and white post- menopausal women? 显示文摘 | EVANS E M ROWE D A GACETTE S B etal | 2006 | Int J Obes (Lond)2006，30，5： | 1 |
| 15 | Thermoelectric figure-of-merit under large temperature differences 显示文摘 | MIN G ROWE D M KONTOSTAVLAKIS K | 2004 | J Phys D:Appl Phys2004，37，8： | 1 |
| 16 | Production and Characterization of Monoclonal Antibodies Against the Poultry Coccidiostat Halofuginone显示文摘 | Rowe L D Beier R C Elissalde M H | 1994 | J Agric Food Chem1994，42，： | 1 |
| 17 | High-temperature refractory metal-intermetallic composites显示文摘 | JACKSON M R BEWLAY B P ROWE R G SKELLY D W LIPSITT H A | 1996 | JOM1996，48，1： | 1 |
| 18 | Thermoelectric figure-of-merit under large temperature differences显示文摘 | MIN G ROWE D M KONTOSTAVLAKIS K | 2004 | Journal of Physics D Applied Physics2004，37，8： | 1 |
| 19 | Detection of Halofuginone Residues in Chicken Serum by a Monoclonal-based Immunoassay and High-perfomance Liquid Chromatography显示文摘 | Beier R C Rowe L D Abd El-Aziz Nasr M I | 1996 | Food & Agricultural Immunology1996，8，： | 1 |
| 20 | Exploiting temperature dependency in the detection of NQR signals显示文摘 | JAKOBSSON A MOSSBERG M ROWE M D | 2006 | IEEE Transactions on Signal Processing2006，54，5： | 1 |
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