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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | A prospective,randomized,placebo controlled,double-blind study of pelvic electromagnetic therapy for the treatment of chronic pelvic pain syndrome with 1 year of followup显示文摘 | Rowe E Smith C Laverick L | 2005 | J Urol2005，173，6： | 1 |
| 3 | Recent developments in acute myelogenous leukemia therapy 显示文摘 | King M E Rowe J M | 2007 | Oncologist2007，12，2： | 1 |
| 4 | Effects of sibutramine on body weight and serum lipids: a double-blind, randomized, placebo-controlled study in 322 overweight and obese patients with dyslipidemia显示文摘 | Dujovne CA Zavoral JH Rowe E eta l | 2001 | Am Heart J2001，142，3： | 1 |
| 5 | Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland 显示文摘 | MAGA E A SHOEMAKER C F ROWE J D | 2006 | Journal of Dairy Science2006，89，2： | 1 |
| 6 | Effects of dietary sodium bicarbonate and calcium chloride on physiological responses of lactating dairy cows in hot weather显示文摘 | ESCOBASA A COPPOCK C E ROWE L D | 1984 | Dairy Sci1984，67，： | 1 |
| 7 | Finite-element modelling of metal flow in three-dimensional forming显示文摘 | HARTLEY P P STURGESS C E N ROWE R W | 1985 | Int J Mach Tool Des Res1985，25，： | 1 |
| 8 | Sustaining IT advantage: the role of structure differenees显示文摘 | CLEMON E ROW M | 1991 | MIS Quarterly1991，15，3： | 1 |
| 9 | Testing the safety-net role of hedgerow tree roots by 15N placement different soil depths显示文摘 | Rowe E C Hairaih K Giner K E | 1999 | Agroforestry System1999，43，： | 1 |
| 10 | Experimen tal Investigation of Heat Transfer in Grinding显示文摘 | Rowe W B Black S C E Mills B | 1995 | CIRP Annals- Manufacturing Technology1995，44，1： | 1 |
| 11 | Ultrahigh-vacuum studies of enhanced Raman scattering from pyridine on Ag surfaces显示文摘 | Rowe J E Shank C V Zwemer D A | 1980 | Phys Rev Lett1980，44，： | 1 |
| 12 | Mohs surgery is the treatment of choice for recurrent(previously treated)basal cell carcinoma显示文摘 | Rowe D E Carroll I U Day C L Jr | 1989 | J Dermatol Surg Oncol1989，15，4： | 1 |
| 13 | Temperature Control in cBN Grinding显示文摘 | Rowe W B Black S C E Mills B | 1996 | Advanced Manufaeturing Technology1996，，12： | 1 |
| 14 | Investigation of the tissue effects of anew device for intracorporeal lithotripsy: the Swiss Lithoclast 显示文摘 | Denstedt JD Razvi HA Rowe E | 1995 | J Urol1995，153，2： | 1 |
| 15 | Cyclooxygenase 2 and intermittent hypoxia-induced spatial deficits in the rat显示文摘 | Li RC Row BW Gozal E | 2003 | Am J Respir Crit Care Med2003，168，4： | 1 |
| 16 | Linear scheduling model: Development of controlling activity path显示文摘 | Harmelink D J Rowings J E | 1998 | Journal of Construction Engineering and Management1998，124，4： | 1 |
| 17 | Epstein-Barr virus-positive Burkitt's lymphoma cells not recognized by virus-specific T-cell surveillance显示文摘 | Rooney C M Rowe M Wallace L E | 1985 | Nature1985，317，： | 1 |
| 18 | Spatial pre-training attenuates hippocampal impairments in rats exposed to intermittent hypoxia显示文摘 | Row BW Goldbart A Gozal E | 2003 | Neurosci Lett2003，339，1： | 1 |
| 19 | Successful treatment of al- opecia areata with efalizumab显示文摘 | Kolde G Meffert H Rowe E | 2008 | J Eur Acad Dermatol Venereol2008，22，3： | 1 |
| 20 | A test of morphological hypotheses for tribal and subtribal relationships of Aphidinae(Insecta:Hemiptera:Aphididae) using DNA seguences显示文摘 | von Dohlen C D Rowe C A Heie O E | | 0，，： | 1 |
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