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| 1 | Quantitative Proteomics Using Isobaric Labeling:A Practical Guide显示文摘In the past decade,relative proteomic quantification using isobaric labeling technology has developed into a key tool for comparing the expression of proteins in biological samples.Although its multiplexing capacity and flexibility make this a valuable technology for addressing various biological questions,its quantitative accuracy and precision still pose significant challenges to the reliability of its quantification results.Here,we give a detailed overview of the different kinds of isobaric mass tags and the advantages and disadvantages of the isobaric labeling method.We also discuss which precautions should be taken at each step of the isobaric labeling workflow,to obtain reliable quantification results in large-scale quantitative proteomics experiments.In the last section,we discuss the broad applications of the isobaric labeling technology in biological and clinical studies,with an emphasis on thermal proteome profiling and proteogenomics. | Xiulan Chen Yaping Sun Tingting Zhang Lian Shu Peter Roepstorff Fuquan Yang | 2021 | Genomics, Proteomics & Bioinformatics2021，19，5： | 5 |
| 2 | Mass spectrometry of nucleic acids显示文摘 | NORDHOFF E KIRPEKAR F ROEPSTORFF P | 1996 | Mass Spectrom Rev1996，15，2： | 1 |
| 3 | Identification of degradation during post-mortem storage of pig meat显示文摘 | Lametsch R Roepstorff P Bendixen E | 2002 | J of Agricultural and Food Chemistry2002，50，： | 1 |
| 4 | Experimental selection of mebendazole resistant gill monogeneans from the European eel, Anguilla Anguilla 显示文摘 | Buchmann K Roepstorff A Wailer P J | 1992 | Journal of Fish Diseases1992，15，5： | 1 |
| 5 | Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle:influence of physical activity and gender显示文摘 | Kiens B Roepstorff and Nielsen JN | 2004 | J Appl Physiol2004，97，： | 1 |
| 6 | Imaging the intentional stance in a competitive game显示文摘 | GALLAGHER H L JACK A I ROEPSTORFF A | 2002 | Neurolmage2002，16，3： | 1 |
| 7 | Detecting deception: the scope and limits显示文摘 | SIP K E ROEPSTORFF A MCGREGOR W | 2008 | Trends in cognitive sciences2008，12，2： | 1 |
| 8 | Language as a tool for interacting minds显示文摘 | Tyl'en K Weed E Wallentin M Roepstorff A & Frith C | | 0，，01： | 1 |
| 9 | Proteomic analysis of S-nitrosylated proteins in Arabidopsis thaliana undergoing hypersensitive response显示文摘 | Romero-Puertas M C Campostrini N Matte A Righetti P G Perazolli M Zolla L Roepstorff P Delledonne M | | 0，，： | 1 |
| 10 | Paralle memory systems for talking about location and age in preeuneus, caudate and Broea's region显示文摘 | Wallentin M Roepstorff A Glover R | 2006 | Neuroimage2006，32，： | 1 |
| 11 | Localization of O-glycosylation sites in peptides by electron capture dissociation in a Fourier transform mass spectrometer显示文摘 | MIRGORODSKAYA E ROEPSTORFF P ZUBAREY R A | 1999 | Anal Chem1999，71，20： | 1 |
| 12 | Studies of plasma membrane fatty acid-binding protein and other lipid-binding proteins in human skeletal muscle显示文摘 | Roepstorff C Helge J and Vistisen B | 2004 | Proceedings of the Nutrition Society2004，63，： | 1 |
| 13 | Introspection and CognitiveBrain Mapping:from Stimulus-response to Script-report显示文摘 | Jack A I Roepstorff A | 2002 | Trends in Cognitive Sciences2002，6，8： | 1 |
| 14 | Insect Cuticular Proteins 显示文摘 | Ansersen S O Hojrup P Roepstorff P | 1995 | Insect Biocbem Mol Biol1995，25，2： | 1 |
| 15 | Effects of phase space discretization on the long-time behavior of dynamical systems显示文摘 | BECK C ROEPSTORFF G | 1987 | Physica D1987，25，13： | 1 |
| 16 | Development of human protein reference database as an initial platform for approaching systems biology in humans 显示文摘 | PERI S NAVARRO J D AMANCHY R KRISTIANSEN T Z JONNALAGADDA C K SURENDRANATH V NIRAN JAN V MUTHUSAMY B GANDHI T K GRONBORG M IBARROLA N DESHPANDE N SHANKER K SHIVASHANKAR H N RASHMI B P RAMYA M A ZHAO Z CHANDRIKA K N PADMA N HARSHA H C YATISH A J KAVITHA M P MENEZES M CHOUDHURY D R SURESH S GHOSH N SARAVANA R CHANDRAN S KRISHNA S JoY M ANAND S K MADAVAN V JOSEPH A WONG G W SCHIEMANN W P CONSTANTINESCU S N HUANG L KHOSRAVI-FAR R STEEN H TEWARI M GHAFFARI S BLOBE G C DANG C V GARCIA J G PEVSNER J JENSEN O N ROEPSTORFF P DESHPANDE K S CHINNAIYAN A M HAMOSH A CHAKRAVARTI A PANDEY A | 2003 | Genome Research2003，13，10： | 1 |
| 17 | Differentiation of cuticular structures during the growth of the third-stage larva of Ascaris suum(Nematoda,Ascaridoidea) after emerging from the egg显示文摘 | Fagerholm HP Nansen P Roepstorff A | 2000 | J Parasitol2000，86，3： | 1 |
| 18 | Identification of protein degradation during postmortem storage of pig meat显示文摘 | Lametsch R Roepstorff P Bendixen E | 2002 | J Agric Food Chem2002，50，20： | 1 |
| 19 | Frontal alpha oscillations distinguish leaders from followers: Multivariate decoding of mutually interacting brains显示文摘 | Ivana Konvalinka Markus Bauer Carsten Stahlhut Lars Kai Hansen Andreas Roepstorff Chris D. Frith | 2014 | NeuroImage2014，，： | 1 |
| 20 | Proteome analysis of the purine stimulon from Lactococcus lactis显示文摘 | BEYER N H ROEPSTORFF P HAMMER K | 2003 | Proteomics2003，3，： | 1 |
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