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| 1 | Role of quorum sensing in bacterial infections显示文摘Quorum sensing(QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate that QS enhances virulence of bacterial pathogens in animal models as well as in human infections; however, its relative importance for bacterial pathogenesis is still incomplete. In this review, we discuss the present evidence from in vitro and in vivo experiments in animal models, as well as from clinical studies, that link QS systems with human infections. We focus on two major QS bacterial models, the opportunistic Gram negative bacteria Pseudomonas aeruginosa and the Gram positive Staphylococcus aureus, which are also two of the main agents responsible of nosocomial and wound infections. In addition, QS communication systems in other bacterial, eukaryotic pathogens, and even immune and cancer cells are also reviewed, and finally, the new approaches proposed to combat bacterial infections by the attenuation of their QS communication systems and virulence are also discussed. | Israel Castillo-Juárez Toshinari Maeda Edna Ayerim Mandujano-Tinoco María Tomás Berenice Pérez-Eretza Silvia Julieta García-Contreras Thomas K Wood Rodolfo García-Contreras | 2015 | World Journal of Clinical Cases2015，3，7： | 15 |
| 2 | Gas chromatography/plasma spectrometry-an important analytical tool for elemental speciation studie显示文摘 | Jorgelina C A Wuilloud Rodolfo G Wuilloud Anne P Vonderheide | 2004 | Spectrochimica Aeta Part B: A- tomic Spectroscopy2004，59，6： | 1 |
| 3 | IL-4-trans-duced tumor cell vaccine induces immunoregulatory type 2T lymphocytes that cure lung metastases upon adoptive transfer显示文摘 | Zilocchi C Accornero P | 1999 | J Immunol1999，163，4： | 1 |
| 4 | Duble-blind,multicenter,randomized trial to compare the effect of two doses of ACTH versus placebo in controlling delayed emesis after high doze cisplatin显示文摘 | Rodolfo P Giorgio C Caterina C | 1997 | J Clin Oncol1997，16，： | 1 |
| 5 | Voltage stability study of the pjm system following extreme disturbances显示文摘 | Rodolfo J K Qiu Wenzheng Mahendra P | 2007 | IEEE Trans on Power Systems2007，22，1： | 1 |
| 6 | Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo 显示文摘 | PAGLIA P CCHIODONIO M RODOLFO W | 1996 | J Exp Med1996，183，： | 1 |
| 7 | Tissue transglutaminase is a multifunctional BH3-ordy protein 显示文摘 | Rodolfo C Mormone E Matarrcse P | 2004 | J Biol Chem2004，279，54： | 1 |
| 8 | On study of design and im- plementation of virtual fixtures 显示文摘 | Rodolfo P Shahram P | 2009 | Virtual Reality2009，13，2： | 1 |
| 9 | Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo 显示文摘 | Paglia P Chiodoni C Rodolfo M | 1996 | J Exp Med1996，183，2： | 1 |
| 10 | Murine dendrtic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo 显示文摘 | Chioldoni C Rodolfo M | 1996 | J Exp Med1996，83，： | 1 |
| 11 | Water reservoir control under economic, social and environmental显示文摘 | ANDREA C FRANCESCA P RODOLFO S S | 2008 | Auto- matica2008，44，5： | 1 |
| 12 | Mortality pattern and stand turnover rates in a wet tropical forest in Costa Rica显示文摘 | DIANA L MILTON L RODOLFO P | 1985 | Journal of Ecology1985，73，3： | 1 |
| 13 | Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo显示文摘 | Chiodonio M Rodolfo | 1996 | J Exp Med1996，183，： | 1 |
| 14 | Microsatellite analysis of the parental contribution of Piaractus mesopo- tamicus to the production of offspring in the semi-natural system of Reproduction显示文摘 | Jayme A P Ricardo P R Rodolfo N S | 2010 | Braz Arch Biol Technol2010，53，： | 1 |
| 15 | Murine dendritic cells loeded in vitro with soluble protein prime cytotoxic Tlymphocytes against tumor antigen in vivo显示文摘 | Paglia P Chiodoni C Rodolfo M | 1996 | J Exp Med1996，1883，： | 1 |
| 16 | Marine dendritic cells loaded in vitro with soluble protein cytotoxic T lymphocytes against tumor antigen in vivo 显示文摘 | Paglia P Chiodoni C Rodolfo M | 1996 | J Exp Med1996，183，1： | 1 |
| 17 | Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic Tlymphocytes against tumor antigen in vivo显示文摘 | Chiodoni C Rodolfo M | 1996 | J Exp Med1996，183，1： | 1 |
| 18 | Tissue transglutaminase is a multifunctional BH3-only protein显示文摘 | Rodolfo C Mormone E Matarrese P | 2004 | J Biol Chem2004，279，54： | 1 |
| 19 | Phase 1 and pharmacodynamic trial of everolimus in combination with cetuximab in patients with advanced cancer显示文摘 | Christine A. Ciunci Rodolfo F. Perini Anjali N. Avadhani Hyunseon C. Kang Weijing Sun Maryann Redlinger Kathleen Harlacker Keith T. Flaherty Bruce J. Giantonio Mark A. Rosen Chaitanya R. Divgi Hee Kwon Song Sarah Englander Andrea Troxel Mitchell Schnall P | 2014 | Cancer2014，，1： | 1 |
| 20 | Murine dendritic cells loaded in vitro with souble protein prime cytotoxic T lymphocytes against tumor antigen in vivo显示文摘 | Pajlia P Chiodoni C Rodolfo M | 1996 | J Exp Med1996，183，： | 1 |
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