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| 1 | Endocrine radionuclide scintigraphy with fusion single photon emission computed tomography/computed tomography显示文摘AIM: To review the benefits of single photon emission computed tomography(SPECT)/computed tomography(CT) hybrid imaging for diagnosis of various endocrine disorders.METHODS: We performed MEDLINE and Pub Med searches using the terms: 'SPECT/CT'; 'functional anatomic mapping'; 'transmission emission tomography'; 'parathyroid adenoma'; 'thyroid cancer'; 'neuroendocrine tumor'; 'adrenal'; 'pheochromocytoma'; 'paraganglioma'; in order to identify relevant articles published in English during the years 2003 to 2015. Reference lists from the articles were reviewed to identify additional pertinent articles. Retrieved manuscripts(case reports, reviews, meta-analyses and abstracts) concerning the application of SPECT/CT to endocrine imaging were analyzed to provide a descriptive synthesis of the utility of this technology.RESULTS: The emergence of hybrid SPECT/CT camera technology now allows simultaneous acquisition of combined multi-modality imaging, with seamless fusion of three-dimensional volume datasets. The usefulness of combining functional information to depict the biodistribution of radiotracers that map cellular processes of the endocrine system and tumors of endocrine origin, with anatomy derived from CT, has improved the diagnostic capability of scintigraphy for a range of disorders of endocrine gland function. The literature describes benefits of SPECT/CT for ^(99m)Tc-sestamibi parathyroid scintigraphy and ^(99m)Tc-pertechnetate thyroid scintigraphy, ^(123)I- or ^(131)I-radioiodine for staging of differentiated thyroid carcinoma, ^(111)In- and ^(99m)Tclabeled somatostatin receptor analogues for detection of neuroendocrine tumors, ^(131)I-norcholesterol(NP-59) scans for assessment of adrenal cortical hyperfunction, and ^(123)I- or ^(131)I-metaiodobenzylguanidine imaging for evaluation of pheochromocytoma and paraganglioma.CONCLUSION: SPECT/CT exploits the synergism between the functional information from radiopharmaceutical imaging and anatomy from CT, translating to improved diagnostic accuracy and meaningful impact on patient care. | Ka-Kit Wong Arpit Gandhi Benjamin L Viglianti Lorraine M Fig Domenico Rubello Milton D Gross | 2016 | World Journal of Radiology2016，8，6： | 3 |
| 2 | Radiofrequency catheter ablation of the atria eliminates pacing induced sustained atrial fibrill-tion and reduces connexin43 in dogs 显示文摘 | Elvan MD Huang MD Milton L | 1997 | Circulation1997，96，17： | 1 |
| 3 | Construction of an evidence-based integrated morphology cleavage embryo score for implantation potential of embryos scored and transferred on day 2 after oocyte retrieval显示文摘 | Holte J Berglund L Milton K | 2007 | Hum Repred2007，22，2： | 1 |
| 4 | Capillary column gas chromatography of environmental polycyclic aromatic compounds 显示文摘 | Lee L Milton Daniel Vassilaros L Douglasr W L | 1982 | Intern J Environ Anal Chem1982，11，： | 1 |
| 5 | Percutaneous Pelvic Fixation Using Working Portals in a Circumferential Pelvic Antishock Sheet显示文摘 | Michael J Gardner Greg Osgood Robert Molnar Milton L Chip Routt | 2009 | Journal of Orthopaedic Trauma2009，，9： | 1 |
| 6 | Scattering of electromagnetic waves from two concentric spheres 显示文摘 | Arthur L Aden Milton Kerker | 1951 | Journal of Applied Physics1951，22，10： | 1 |
| 7 | Casimir effect in dielectrics显示文摘 | de Raad L L Milton K A | 1978 | Ann Phys1978，115，： | 1 |
| 8 | Gene transcription of neuroglobin is upregulated by hypoxia and anoxia in the brain of the anoxia - tolerant turtle trachemys scripta 显示文摘 | Milton S L Nayak G Lutz P L | 2006 | Bomediacal Sci2006，13，4： | 1 |
| 9 | Radiofrequency catheter ablation of the atria eliminates pacing induced sustained atrial fibrillation and reduces connexin43 in dogs 显示文摘 | Elvan MD Huang MD Milton L | 1997 | Circulation1997，96，17： | 1 |
| 10 | Microstructural Analyses and Wear Behavior of the Cemented Carbide Tools after Laser Surface Treatment and PVD Coating显示文摘 | DAVI N ANSELMOD MILTON L | 2013 | Applied Surface Science2013，282，： | 1 |
| 11 | Chemotactic motility is required for invasion of the host by the fish pathogen Vibrio anguillarum显示文摘 | O'Toole R Milton D L Wolf-Watz H | 1996 | Molecular Microbiol- ogy1996，19，3： | 1 |
| 12 | Glycogen metabolism and ultimate pH of muscle in Merino,first-cross,and second-cross whether lambs as affected by stress before slaughter显示文摘 | Gardener G E Kennedy L Milton J T B | 1999 | Australian Journal of Agricultural Research1999，50，： | 1 |
| 13 | Neuroprotective sig- naling pathways are modulated by adenosine in the anoxia tolerant turtle显示文摘 | Nayak G H Prentice H M Milton S L | 2011 | J Cereb Blood Flow Metab2011，31，2： | 1 |
| 14 | The impact of & singlel&yer or double-i&yer closure on uterine upture显示文摘 | Bujold E BujoId C H&milton EF et &l | 2002 | Am J Obstet Gynecol2002，186，6： | 1 |
| 15 | Cloning of a metalloprotease gene involved in the virulence mechanism of Vibrio anguillarum显示文摘 | Milton D L Norqvist A Wolf-Watz H | 1992 | J Bacteriol1992，174，22： | 1 |
| 16 | Chemical class separation and Characterization of organic compounds in synthetic fuels显示文摘 | Larter Douglas W Lee Milton L Bartle Keith D | 1981 | Analytical Chemistry1981，53，： | 1 |
| 17 | A functionally distinct member of the DP family ofE2F subunits显示文摘 | Milton A Luoto K Ingram L | | 0，，22： | 1 |
| 18 | Capitalizing on diversity: Interpersonal congruence in small work groups显示文摘 | POLZER J T MILTON L P SWANN JR W B | 2002 | Administrative Science Quarterly2002，47，2： | 1 |
| 19 | The stresses on the surface of a sphere: An solution via Green's functions显示文摘 | Milton K A DeRaad L L Schwinger J | 1978 | Ann Phys1978，115，2： | 1 |
| 20 | Chemical class separation and characterization of organic compounds in synthetic fuels显示文摘 | Later Douglas W Lee Milton L Bartle Kelth D | 1981 | Anal Chem1981，53，： | 1 |
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