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| 1 | Serum vitamin D content is associated with semen|parameters and serum testosterone levels in men显示文摘The present study aimed to evaluate the influence of serum vitamin D levels on semen quality and testosterone levels.This is a crosssectional study conducted at Androscience,Science and Innovation Center in Andrology and High-Complex Clinical and Andrology Laboratory in Sao Paulo,Brazil,with 508 male patients,aged 18-60 years,from 2007 to 2017.Seminal parameters and serum sexual hormones were correlated with serum vitamin D concentrations in 260 men selected by strict selection criteria.Patients were divided into normozoospermic group(NZG,n=124)and a group with seminal abnormalities(SAG,n=136).Evaluation included complete physical examination,past medical history,habits and lifestyle factors,two complete seminal analysis with sperm functional tests,serum levels of 25-hydroxy-vitamin D_(3)(25(OH)VD_(3)),total and free testosterone,luteinizing hormone(LH),follicle-stimulating hormone(FSH),sex hormone-binding globulin(SHBG),total cholesterol,homeostatic model assessment of insulin resistance(HOMA-IR)index,and karyotype.The mean concentration of 25(OH)VD_(3)was significantly lower in the SAG(P<0.001)and positively correlated with all baseline seminal parameters and total testosterone levels.In addition,serum vitamin D_(3)concentration was found to be positively correlated with sperm concentration(β=2.103;P<0.001),total number of spermatozoa with progressive motility(β=2.069;P=0.003),total number of motile spermatozoa(β=2.571;P=0.015),and strict morphology(β=0.056;P=0.006),regardless of other variables.This is the first comparative study to address the issue of serum vitamin D_(3)content between normozoospermic patients and those with sperm abnormalities.It clearly demonstrates a direct and positive relationship between serum vitamin D level and overall semen quality,male reproductive potential,and testosterone levels. | Inari M Ciccone Elaine MF Costa Juliana R Pariz Thiago A Teixeira Joel R Drevet Parviz Gharagozloo Robert J Aitken Jorge Hallak | 2021 | Asian Journal of Andrology2021，23，1： | 2 |
| 2 | Three-dimensional MR imaging of pulmonary vessels and parenchyma with NC100150 injection (Clariscan)显示文摘 | Bremerich J Roberts TP Wendland MF | 2000 | J Magn Reson Imaging2000，11，6： | 1 |
| 3 | Development of a health-protective drinking water level for perchlorate显示文摘 | David T Robert AH Anna MF | | 0，，： | 1 |
| 4 | Reconstruction of a neocosdyle using transport distraction osteogenesis 显示文摘 | Stucki-McCortnik SU Robert MF Ronald DM | 1999 | Semis Orthod1999，5，1： | 1 |
| 5 | Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punetata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes显示文摘 | Fishman GA Roberts MF Derlacki D J | 2004 | Arch Ophthalmol2004，122，1： | 1 |
| 6 | DNMT1 is required to maintain CPG methylation and aberrant gene silencing in human cancer cell显示文摘 | Robert MF Morin S Beaulieu N | | 0，，： | 1 |
| 7 | DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells显示文摘 | Robert MF Morin S Beaulieu N | 2003 | Nat Genet2003，33，： | 1 |
| 8 | Habitual abortions in 678 healthy patients: investigation and prevention显示文摘 | Reznikoff-Etievant MF Cayol V Zou GM Abuaf N Robert A Johanet C Milliez J | 1999 | Human Reproduction1999，14，8： | 1 |
| 9 | The cyclohexane moiety of rapamycin is derived from shikimic acid in Streptomyces hygroscopicus显示文摘 | Paiva NL Roberts MF Demain AL | 1993 | Journal of Industrial Microbiology & Biotechnology1993，12，6： | 1 |
| 10 | Early intestinal bacterial colonization and necrotizing enterocolitis in premature infants:the putative role of Clostridium显示文摘 | De La Cochetiere MF Piloquet H Des Robert C | 2004 | Pediatr Res2004，56，3： | 1 |
| 11 | DNMTI is required to maintain CpG methylation and aberrant gene silencing in human cancer cells显示文摘 | Robert MF Morin S Beaulieu N | | 0，，01： | 1 |
| 12 | The relation-ship between dose of vitamin E and suppression of oxida-tive stress in humans显示文摘 | Roberts LJ 2nd Oates JA Linton MF | 2007 | Free Radical Biol Med2007，43，10： | 1 |
| 13 | Potentiation of the antimalarial activity ofqinghaosu by methoxylated flavones显示文摘 | ELFORD BC ROBERTS MF PHILLIPSON JD | 1987 | T Roy Soc Trop MedH1987，81，3： | 1 |
| 14 | Three-dimensional MR imaging of pulmonary vessels and parenchyma with NC100150 injection (Clariscan)显示文摘 | Bremerich J Roberts TP Wendland MF | 2000 | J Magn Reson Imaging2000，11，6： | 1 |
| 15 | Antimalarial activity of Artemisia armua flavonoids from whole plants and cell cultures显示文摘 | L1U KCSC YANG SL ROBERTS MF | 1999 | Plant Cell Rep1999，11，12： | 1 |
| 16 | Antimalarial activity of Artemisia annua flavonoids from whole plants and cell cultures显示文摘 | LIU KCS YANG SL ROBERTS MF | 1992 | Plant Cell Rep1992，11，： | 1 |
| 17 | 3 -Hydroxy -3 -methylglu- taryl - coenzyme A lyase(HL) :Cloning of human and chicken liver ttL cDNAs and characterization of a mutation causing human HL deficiency 显示文摘 | Mitchell GA Robert MF Hruz PW | 1993 | J Biol Chem1993，268，6： | 1 |
| 18 | Novel mutations in the cellular retinaldehyde-binding protein gene (RLBPI) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes显示文摘 | Fishman GA Roberts MF Derlacki DJ | 2004 | Arch Ophthalmol2004，122，1： | 1 |
| 19 | Reracking of transmembrane domains of P-glycoprotein during the transport ATPase cycle显示文摘 | Rosenberg MF Velarde GF Robert CM | 2001 | EMBO2001，20，： | 1 |
| 20 | Association between maternal diabetes and the respiratory-distress syndrome in the newborn显示文摘 | Robert MF Neff RK Hubbell JP | 1976 | NEnglJ Med1976，294，7： | 1 |
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