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| 1 | Overview of extended release tacrolimus in solid organ transplantation显示文摘Tacrolimus(Prograf?, Astellas Pharma Europe Ltd, Staines, United Kingdom; referred to as tacrolimusBID) is an immunosuppressive agent to prevent and treat allograft rejection in kidney transplant recipients in combination with mycophenolate mofetil, corticosteroids,with or without basiliximab induction. The drug has also been studied in liver, heart and lung transplant; however, these are currently off-label indications. An extended release tacrolimus formulation(Advagraf?, Astagraf XL?) allows for once-daily dosing, with the potential to improve adherence. Extended release tacrolimus has similar absorption, distribution, metabolism and excretion to tacrolimus-BID. Phase Ⅰ pharmacokinetic trials comparing extended release tacrolimus and tacrolimus-BID have demonstrated a decreased maximum concentration(C max) and delayed time to maximum concentration(t max) with the extended release formulation; however, AUC0-24 was comparable between formulations. Overall extended release tacrolimus has a very similar safety and efficacy profile to tacrolimus-BID. It is not recommended in the use of liver transplant patient's due to the increased risk of mortality in female recipients. There has been minimal data regarding the use of extended release tacrolimus in heart and lung transplant recipients. With the current data available for all organ groups the extended release tacrolimus should be dosed in a 1:1 fashion, the exception may be the cystic fibrosis population where their initial dose may need to be higher. | Neha Patel Abigail Cook Elizabeth Greenhalgh Megan A Rech Joshua Rusinak Lynley Heinrich | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 2 | Continuous glucose monitoring in diabetic women fol|owing antenatal corticosteroid therapy: a pilot study 显示文摘 | Refuerzo JS Garg A Rech B | 2012 | Am J Perinatol2012，，29： | 1 |
| 3 | Nucleation and growth of faults in brittle rocks 显示文摘 | Reches Z Lockner D A | 1994 | J GeophysRes1994，99，18： | 1 |
| 4 | Photodynamic therapy of onychomycosis caused by Trichophyton rubrum显示文摘 | Piraccini BM Rech G Tosti A | 2008 | J Am Acad Dermatol2008，59，5： | 1 |
| 5 | Continuous glucose monitoring indiabetic wonlen following antenatal corticosteroid therapy: a pilotSmdy显示文摘 | Kefuerzo JS Garg A Rech B | 2012 | AmJ Perinatol2012，，29： | 1 |
| 6 | RANi-mediated silencing of the myo- inositol phosphate synthase gene (GmMIPS) in trans-genic soybean inhibited seed development and reduced phytate content 显示文摘 | Nunes A C S Vianna G R Cuneo F Amaya F J Capdeville G Rech E L Arogao F J L | 2006 | P[anta2006，224，1： | 1 |
| 7 | Clinical use of anti-CD25 an- tibody daclizumab to enhance immune responses to tu- mor antigen vaccination by targeting regulatory T cells 显示文摘 | Rech A J Vonderheide RH | 2009 | Ann N Y Acad Sci2009，1174，： | 1 |
| 8 | Laparoscopic cystectomy and iteal conduit: case report 显示文摘 | Sanchez de B E Gallego P J L Reche R A | 1995 | J Endourol1995，9，1： | 1 |
| 9 | Human thymic stromal lymphopoietin preferentially stimulates myeloid cells显示文摘 | Reche P A Soumelis V Gorman D M | 2001 | J Immunol2001，167，： | 1 |
| 10 | The vascular expression pattern directed by the Eucalyptus gunnii cinnamyl alcohol dehydrogenase EgCAD2 promoter is conserved among woody and herbaceous plant species显示文摘 | Lauvergeat V Rech P Jauneau A | 2002 | Plant Mol Biol2002，50，： | 1 |
| 11 | Wear resistance of coatings in high-speed gear hobbing显示文摘 | Rech J Djouadi M A Picot J | 2001 | Wear2001，250，1： | 1 |
| 12 | Sequences variability analysis of human class I and class II MHC molecules: Functional and structural correlates of amino acids polymorphisms显示文摘 | Reche P A Reinherz E L | 2003 | J Mol Biol2003，331，3： | 1 |
| 13 | 显示文摘 | SANCHEZ D B E GALLEGO P J RECHE R A | 1993 | Arch Esp Urol1993，46，7： | 1 |
| 14 | Effect of the treatment with achyrocline satureioides (free and nanocapsules essential oil) and diminazene aceturate on hematological and biochemical parameters in rats infected by trypanosoma evansi显示文摘 | Guilherme M. Do Carmo Matheus D. Baldissera Rodrigo A. Vaucher Virginia Cielo Rech Camila B. Oliveira Michele Rorato Sagrillo Aline A. Boligon Margareth L. Athayde Marta P. Alves Raqueli T. Fran?a Sonia T.A. Lopes Claiton I. Schwertz Ricardo E. Mendes Sil | 2014 | Experimental Parasitology2014，，： | 1 |
| 15 | Genome-wide characterization of a viral cytotoxic T lymphocyte epitope显示文摘 | Zhong W M Reche P A Lai C C | 2003 | The Journal of Biological Chemistry2003，278，45： | 1 |
| 16 | Evolution ofChaka Salt Lake in NW China in response to climatic changeduring the Latest Pleistocene-Holocene显示文摘 | Liu Xingqi Dong Hailiang Rech J A | 2008 | Quaternary Sci-ence Reviews2008，27，： | 1 |
| 17 | Rigid,self-assembled hydrogel composed of a modified aromatic dipeptide显示文摘 | Mahler A Reches M Rechter M | 2006 | Adv Mater2006，18，11： | 1 |
| 18 | Volumetric reconstruction and interactive endering of trees from photographs显示文摘 | RECHE MARTINEZ A MARTIN I DRETTAKIS G | 2004 | ACM Transactions on Graphics2004，23，3： | 1 |
| 19 | Low-Cost Printing of Poly ( Dimethylsiloxane) Barriers to Define Microchannels in Paper显示文摘 | Bruzewicz D A Reches M Whitesides G M | 2008 | Anal Chem2008，80，9： | 1 |
| 20 | Volumetric reconstruction and interactive rendering of trees from photographs显示文摘 | Reche A Martin I Drettakis G | 2004 | ACM Transactions on Graphics2004，23，： | 1 |
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