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| 1 | 基于博弈论的信息安全技术评价模型显示文摘信息安全在企业信息系统建设中越来越重要,如何评价信息安全技术成为当前的一个研究课题.文中基于博弈论,对由防火墙、入侵检测系统和容忍入侵技术构成的三层安全体系结构进行了分析,提出了对信息安全技术进行评价的模型.在对入侵检测系统分析评价的基础上,重点分析了防火墙、入侵检测与容忍入侵的相互影响和关系.研究表明,IDS的检测率、误报率与防火墙的性能有密切关系,系统安全配置直接影响信息安全机制的性能和成本效益,容忍入侵机制取决于入侵的损失评估、系统的成本和防火墙与IDS的性能.信息安全机制的优化配置对于信息安全的效果具有重要影响. | 朱建明 Srinivasan Raghunathan | 2009 | 计算机学报2009，32，4： | 42 |
| 2 | Controversies in fluid therapy: Type, dose and toxicity显示文摘Fluid therapy is perhaps the most common intervention received by acutely ill hospitalized patients; however, a number of critical questions on the efficacy and safety of the type and dose remain. In this review, recent insights derived from randomized trials in terms of fluid type, dose and toxicity are discussed. We contend that the prescription of fluid therapy is context-specific and that any fluid can be harmful if administered inappropriately. When contrasting ‘‘crystalloid vs colloid'', differences in efficacy are modest but differences in safety are significant. Differences in chloride load and strong ion difference across solutions appear to be clinically important. Phases of fluid therapy in acutely ill patients are recognized, including acute resuscitation, maintaining homeostasis, and recovery phases. Quantitative toxicity(fluid overload) is associated with adverse outcomes and can be mitigated when fluid therapy basedon functional hemodynamic parameters that predict volume responsiveness and minimization of non-essential fluid. Qualitative toxicity(fluid type), in particular for iatrogenic acute kidney injury and metabolic acidosis, remain a concern for synthetic colloids and isotonic saline, respectively. Physiologically balanced crystalloids may be the ‘‘default'' fluid for acutely ill patients and the role for colloids, in particular hydroxyethyl starch, is increasingly unclear. We contend the prescription of fluid therapy is analogous to the prescription of any drug used in critically ill patients. | Robert C McDermid Karthik Raghunathan Adam Romanovsky Andrew D Shaw Sean M Bagshaw | 2014 | World Journal of Critical Care Medicine2014，3，1： | 5 |
| 3 | Combined heat and power economic dispatch problem using firefly algorithm显示文摘 | Afshin YAZDANI T. JAYABARATHI V. RAMESH T. RAGHUNATHAN | 2013 | Frontiers in Energy2013，7，2： | 5 |
| 4 | Combined heat and power economic dispatch problem using the invasive weed optimization algorithm显示文摘 | T. JAYABARATHI Afshin YAZDANI V. RAMESI T. RAGHUNATHAN | 2014 | Frontiers in Energy2014，8，1： | 4 |
| 5 | Critical role of OX40 signaling in the TCR-independent phase of human and murine thymic Treg generation显示文摘Regulatory T cells(Tregs)play a pivotal role in immune-tolerance,and loss of Treg function can lead to the development of autoimmunity.Natural Tregs generated in the thymus substantially contribute to the Treg pool in the periphery,where they suppress self-reactive effector T cells(Teff)responses.Recently,we showed that OX40L(TNFSF4)is able to drive selective proliferation of peripheral Tregs independent of canonical antigen presentation(CAP-independent)in the presence of low-dose IL-2.Therefore,we hypothesized that OX40 signaling might be integral to the TCR-independent phase of murine and human thymic Treg(tTreg)development.Development of tTregs is a two-step process:Strong T-cell receptor(TCR)signals in combination with co-signals from the TNFRSF members facilitate tTreg precursor selection,followed by a TCR-independent phase of tTreg development in which their maturation is driven by IL-2.Therefore,we investigated whether OX40 signaling could also play a critical role in the TCR-independent phase of tTreg development.OX40−/−mice had significantly reduced numbers of CD25−Foxp3low tTreg precursors and CD25+Foxp3+mature tTregs,while OX40L treatment of WT mice induced significant proliferation of these cell subsets.Relative to tTeff cells,OX40 was expressed at higher levels in both murine and human tTreg precursors and mature tTregs.In ex vivo cultures,OX40L increased tTreg maturation and induced CAP-independent proliferation of both murine and human tTregs,which was mediated through the activation of AKT-mTOR signaling.These novel findings show an evolutionarily conserved role for OX40 signaling in tTreg development and proliferation,and might enable the development of novel strategies to increase Tregs and suppress autoimmunity. | Prabhakaran Kumar Alejandra Marinelarena Divya Raghunathan Vandhana K Ragothaman Shikha Saini Palash Bhattacharya Jilao Fan Alan L Epstein Ajay V Maker Bellur S Prabhakar | 2019 | Cellular & Molecular Immunology2019，16，2： | 4 |
| 6 | Aerodynamics of high-speed railway train显示文摘 | Raghu S Raghunathan H.-D Kim T Setoguchi | 2002 | Progress in Aerospace Sciences2002，，6： | 4 |
| 7 | Studies on the seasonal variations in the proximate composition of ascidians from the Palk Bay,Southeast coast of India显示文摘Objective:To investigate the seasonal fluctuations of the proximate composition of the ascidians muscle.Methods:The moisture content was estimated by drying 1 g of fresh tissue at a constant temperature at 105(?)for 24 h.The loss of weight was taken as moisture content.The total protein was estimated using the Biuret method.The total carbohydrate in dried sample was estimated spectrophotometrically following the phenol-sulphuric acid method.The lipid in the dried sample tissue was gravimetrically estimated following the chloroform-methanol mixture method.Ash content was determined gravimetrically by incinerating 1 g dried sample in muffle furnace at about 550℃for 6 h and results are expressed in percentage.Results:It was found very difficult to compare the monthly variations,as all the ten species,exhibited wide fluctuations in their proximate compositions.For the sake of convenience,average seasonal values were calculated by summing the monthly values.Conclusions:The proximate composition of the 10 commonly available ascidians showed high nutritive value and hence these groups especially solitary ascidians can be recommended for human consumption in terms of pickles,soup,curry and others after ensuring the safety of consumers. | Ananthan G Karthikeyan MM Selva Prabhu A Raghunathan C | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 3 |
| 8 | RETRACTED: The Effect of Cyclooxygenase-2 Inhibition on Acute and Chronic Donor-Site Pain after Spinal-Fusion Surgery显示文摘 | Scott S. Reuben Evan F. Ekman Karthik Raghunathan Robert B. Steinberg Jordan L. Blinder John Adesioye | 2006 | Regional Anesthesia and Pain Medicine2006，，1： | 2 |
| 9 | The effect of cyclooxygenase-2 inhibition on acute and chronic donorsite pain after spinal-fusion surgery显示文摘 | Reuben SS Ekman EF Raghunathan K | 2006 | Reg Anesth Pain Med2006，31，1： | 1 |
| 10 | The Impacts of the Full Returns Policy on a Supply Chain with Information Asymmetry显示文摘 | Xiaohang Yue Srinivasan Raghunathan | 2007 | European Journal of Operational Research2007，180，： | 1 |
| 11 | A feedback-based scheme for improving TCP performance in ad hoc wireless networks显示文摘 | Chandran K Raghunathan S Venkatesan S | 2001 | IEEE Personal Communications Magazine2001，8，1： | 1 |
| 12 | Diffusionthrough CaSC>4 formed during the reaction of CaO withS02and 02显示文摘 | Hsia C? St Pierre GR Raghunathan K | 1993 | AIChE Journal1993，39，4： | 1 |
| 13 | Aerodynamics of high-speed railway train显示文摘 | Raghu S Raghunathan H D Setoguchic K T | 2002 | Progress in Aerospace Sciences2002，38，： | 1 |
| 14 | Ge- nomic DNA amplification from a single bacterium 显示文摘 | Raghunathan A Ferguson HR Jr Bornarth C J | 2005 | Appl Environ Microbiol2005，71，6： | 1 |
| 15 | The ef- fect of cyclooxygenase-2 inhibition on acute and chronic donor site pain after spinal fusion surgery显示文摘 | REUBEN SS EKMAN EF RAGHUNATHAN K | 2006 | Reg Anesth Pain Med2006，31，3： | 1 |
| 16 | Emerging tech- niques for long lived wireless sensor network显示文摘 | Raghunathan V Ganeriwal S Srivastava M | 2006 | IEEE Com- munications Magazine2006，44，4： | 1 |
| 17 | Information sharing in a supply chain: A note on its value when demand is non-stationary显示文摘 | Raghunathan S | 2001 | Management Science2001，47，： | 1 |
| 18 | Security in embedded systems: design challenges显示文摘 | Ravi S Raghunathan A Kocher P | 2004 | ACM Transactions on Embedded Computing Systems2004，3，3： | 1 |
| 19 | Energy Macro-modeling of Embedded Operating Systems显示文摘 | Tan T K Raghunathan A Jha N K | 2005 | ACM Transactions on Embedded Computing Systems2005，4，1： | 1 |
| 20 | Chemical diffusion in the bcc phase of the Zr-Ti alloy 显示文摘 | RAGHUNATHAN V R TIWARI G R SHARMA B D | 1972 | Metallurgical and Materials Transactions B1972，3，： | 1 |
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